UA77468C2 - Use of n-(indolcarbonyl) piperazin derivatives - Google Patents
Use of n-(indolcarbonyl) piperazin derivatives Download PDFInfo
- Publication number
- UA77468C2 UA77468C2 UA20040604937A UA20040604937A UA77468C2 UA 77468 C2 UA77468 C2 UA 77468C2 UA 20040604937 A UA20040604937 A UA 20040604937A UA 20040604937 A UA20040604937 A UA 20040604937A UA 77468 C2 UA77468 C2 UA 77468C2
- Authority
- UA
- Ukraine
- Prior art keywords
- formula
- compounds
- unsubstituted
- indol
- piperazin
- Prior art date
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- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 claims description 19
- 125000004194 piperazin-1-yl group Chemical group [H]N1C([H])([H])C([H])([H])N(*)C([H])([H])C1([H])[H] 0.000 claims description 15
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- 238000007911 parenteral administration Methods 0.000 description 1
- 125000004817 pentamethylene group Chemical group [H]C([H])([*:2])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[*:1] 0.000 description 1
- 125000003538 pentan-3-yl group Chemical group [H]C([H])([H])C([H])([H])C([H])(*)C([H])([H])C([H])([H])[H] 0.000 description 1
- 125000001147 pentyl group Chemical group C(CCCC)* 0.000 description 1
- 229940066842 petrolatum Drugs 0.000 description 1
- JTJMJGYZQZDUJJ-UHFFFAOYSA-N phencyclidine Chemical compound C1CCCCN1C1(C=2C=CC=CC=2)CCCCC1 JTJMJGYZQZDUJJ-UHFFFAOYSA-N 0.000 description 1
- 229950010883 phencyclidine Drugs 0.000 description 1
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- 125000001501 propionyl group Chemical group O=C([*])C([H])([H])C([H])([H])[H] 0.000 description 1
- 125000003373 pyrazinyl group Chemical group 0.000 description 1
- 125000002206 pyridazin-3-yl group Chemical group [H]C1=C([H])C([H])=C(*)N=N1 0.000 description 1
- 125000004941 pyridazin-5-yl group Chemical group N1=NC=CC(=C1)* 0.000 description 1
- BKXVVCILCIUCLG-UHFFFAOYSA-N raloxifene hydrochloride Chemical compound [H+].[Cl-].C1=CC(O)=CC=C1C1=C(C(=O)C=2C=CC(OCCN3CCCCC3)=CC=2)C2=CC=C(O)C=C2S1 BKXVVCILCIUCLG-UHFFFAOYSA-N 0.000 description 1
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Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/496—Non-condensed piperazines containing further heterocyclic rings, e.g. rifampin, thiothixene or sparfloxacin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Neurology (AREA)
- Organic Chemistry (AREA)
- Biomedical Technology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Neurosurgery (AREA)
- Epidemiology (AREA)
- Psychiatry (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Anesthesiology (AREA)
- Pain & Pain Management (AREA)
- Hospice & Palliative Care (AREA)
- Child & Adolescent Psychology (AREA)
- Diabetes (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Indole Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE10157673A DE10157673A1 (de) | 2001-11-24 | 2001-11-24 | Verwendung von N-(Indolcarbonyl-)piperazinderivaten |
| PCT/EP2002/012009 WO2003045392A2 (de) | 2001-11-24 | 2002-10-28 | Verwendung von n-(indolcarbonyl-)piperazinderivaten |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| UA77468C2 true UA77468C2 (en) | 2006-12-15 |
Family
ID=7706831
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| UA20040604937A UA77468C2 (en) | 2001-11-24 | 2002-10-28 | Use of n-(indolcarbonyl) piperazin derivatives |
Country Status (23)
| Country | Link |
|---|---|
| US (1) | US20050014766A1 (zh) |
| EP (1) | EP1448201B1 (zh) |
| JP (1) | JP2005511640A (zh) |
| KR (1) | KR100953172B1 (zh) |
| CN (1) | CN1319532C (zh) |
| AR (1) | AR037404A1 (zh) |
| AU (1) | AU2002349012B2 (zh) |
| BR (1) | BR0214347A (zh) |
| CA (1) | CA2468380A1 (zh) |
| DE (2) | DE10157673A1 (zh) |
| ES (1) | ES2297018T3 (zh) |
| HK (1) | HK1073243A1 (zh) |
| HU (1) | HUP0402388A3 (zh) |
| IL (2) | IL162125A0 (zh) |
| MX (1) | MXPA04004766A (zh) |
| MY (1) | MY141210A (zh) |
| NZ (1) | NZ533667A (zh) |
| PE (1) | PE20030710A1 (zh) |
| PL (1) | PL207565B1 (zh) |
| RU (1) | RU2317083C2 (zh) |
| UA (1) | UA77468C2 (zh) |
| WO (1) | WO2003045392A2 (zh) |
| ZA (1) | ZA200404967B (zh) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE10246357A1 (de) * | 2002-10-04 | 2004-04-15 | Merck Patent Gmbh | Verwendung von 5-HT2Rezeptorantagonisten |
| DE102004047517A1 (de) | 2004-09-28 | 2006-03-30 | Merck Patent Gmbh | Neuartige Kristallform von (3-Cyan-1H-indol-7-yl)-[4-(4-fluorphenethyl)-piperazin-1-yl]-methanon, Hydrochlorid |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE3582371D1 (de) * | 1984-07-06 | 1991-05-08 | Otsuka Pharma Co Ltd | Oxindolverbindungen, diese enthaltende zusammensetzungen sowie verfahren zur herstellung derselben. |
| GB9718712D0 (en) * | 1997-09-03 | 1997-11-12 | Merck Sharp & Dohme | Theraputic Agents |
| CN1289475C (zh) * | 1998-04-29 | 2006-12-13 | 奥索-麦克尼尔药品公司 | 在肥胖症和其它病症的治疗中用作神经肽yy5受体配体的n－取代的氨基1,2,3,4－四氢化萘 |
| GB9825413D0 (en) * | 1998-11-19 | 1999-01-13 | Lilly Co Eli | Pharmaceutical compounds |
| DE19934432A1 (de) * | 1999-07-22 | 2001-02-01 | Merck Patent Gmbh | Indolderivate |
| DE19934433A1 (de) * | 1999-07-22 | 2001-01-25 | Merck Patent Gmbh | N-(Indolcarbonyl-)piperazinderivate |
| HUP0202678A3 (en) * | 1999-09-30 | 2004-06-28 | Pfizer | Certain alkylene diamine-substituted pyrazolo[1,5,-a]-1,5-pyrimidines and pyrazolo[1,5-a]-1,3,5-triazines, pharmaceutical compositions containing them and their use |
-
2001
- 2001-11-24 DE DE10157673A patent/DE10157673A1/de not_active Withdrawn
-
2002
- 2002-10-28 RU RU2004119303/15A patent/RU2317083C2/ru not_active IP Right Cessation
- 2002-10-28 ES ES02781293T patent/ES2297018T3/es not_active Expired - Lifetime
- 2002-10-28 KR KR1020047006419A patent/KR100953172B1/ko not_active IP Right Cessation
- 2002-10-28 NZ NZ533667A patent/NZ533667A/en not_active IP Right Cessation
- 2002-10-28 US US10/496,572 patent/US20050014766A1/en not_active Abandoned
- 2002-10-28 BR BR0214347-0A patent/BR0214347A/pt not_active IP Right Cessation
- 2002-10-28 WO PCT/EP2002/012009 patent/WO2003045392A2/de active IP Right Grant
- 2002-10-28 JP JP2003546894A patent/JP2005511640A/ja active Pending
- 2002-10-28 DE DE50211298T patent/DE50211298D1/de not_active Expired - Lifetime
- 2002-10-28 UA UA20040604937A patent/UA77468C2/uk unknown
- 2002-10-28 CA CA002468380A patent/CA2468380A1/en not_active Abandoned
- 2002-10-28 MX MXPA04004766A patent/MXPA04004766A/es active IP Right Grant
- 2002-10-28 PL PL369675A patent/PL207565B1/pl not_active IP Right Cessation
- 2002-10-28 IL IL16212502A patent/IL162125A0/xx unknown
- 2002-10-28 CN CNB028230620A patent/CN1319532C/zh not_active Expired - Fee Related
- 2002-10-28 AU AU2002349012A patent/AU2002349012B2/en not_active Ceased
- 2002-10-28 EP EP02781293A patent/EP1448201B1/de not_active Expired - Lifetime
- 2002-10-28 HU HU0402388A patent/HUP0402388A3/hu unknown
- 2002-11-20 PE PE2002001114A patent/PE20030710A1/es not_active Application Discontinuation
- 2002-11-20 MY MYPI20024337A patent/MY141210A/en unknown
- 2002-11-22 AR ARP020104495A patent/AR037404A1/es unknown
-
2004
- 2004-05-23 IL IL162125A patent/IL162125A/en not_active IP Right Cessation
- 2004-06-23 ZA ZA200404967A patent/ZA200404967B/en unknown
-
2005
- 2005-07-11 HK HK05105839A patent/HK1073243A1/xx not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| WO2003045392A2 (de) | 2003-06-05 |
| WO2003045392A3 (de) | 2003-09-18 |
| IL162125A (en) | 2010-12-30 |
| ZA200404967B (en) | 2005-08-05 |
| NZ533667A (en) | 2006-11-30 |
| MXPA04004766A (es) | 2004-07-30 |
| PE20030710A1 (es) | 2003-08-21 |
| DE10157673A1 (de) | 2003-06-05 |
| RU2004119303A (ru) | 2005-04-20 |
| HUP0402388A2 (hu) | 2005-03-29 |
| HK1073243A1 (en) | 2005-09-30 |
| EP1448201B1 (de) | 2007-11-28 |
| CA2468380A1 (en) | 2003-06-05 |
| BR0214347A (pt) | 2004-10-26 |
| US20050014766A1 (en) | 2005-01-20 |
| HUP0402388A3 (en) | 2009-08-28 |
| MY141210A (en) | 2010-03-31 |
| PL369675A1 (en) | 2005-05-02 |
| JP2005511640A (ja) | 2005-04-28 |
| IL162125A0 (en) | 2005-11-20 |
| CN1319532C (zh) | 2007-06-06 |
| CN1589147A (zh) | 2005-03-02 |
| PL207565B1 (pl) | 2011-01-31 |
| AR037404A1 (es) | 2004-11-10 |
| KR100953172B1 (ko) | 2010-04-20 |
| ES2297018T3 (es) | 2008-05-01 |
| EP1448201A2 (de) | 2004-08-25 |
| WO2003045392A8 (de) | 2004-12-29 |
| DE50211298D1 (de) | 2008-01-10 |
| KR20040072624A (ko) | 2004-08-18 |
| RU2317083C2 (ru) | 2008-02-20 |
| AU2002349012A1 (en) | 2003-06-10 |
| AU2002349012B2 (en) | 2008-01-24 |
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