UA74335C2 - Мультичастинкова композиція контрольованого вивільнення флувоксаміну та спосіб лікування станів, які лікуються за допомогою селективних інгібіторів зворотного захоплення серотоніну - Google Patents
Мультичастинкова композиція контрольованого вивільнення флувоксаміну та спосіб лікування станів, які лікуються за допомогою селективних інгібіторів зворотного захоплення серотонінуInfo
- Publication number
- UA74335C2 UA74335C2 UA2001128821A UA2001128821A UA74335C2 UA 74335 C2 UA74335 C2 UA 74335C2 UA 2001128821 A UA2001128821 A UA 2001128821A UA 2001128821 A UA2001128821 A UA 2001128821A UA 74335 C2 UA74335 C2 UA 74335C2
- Authority
- UA
- Ukraine
- Prior art keywords
- controlled release
- serotonin reuptake
- selective serotonin
- release formulation
- formulation containing
- Prior art date
Links
- 239000000203 mixture Substances 0.000 title abstract 5
- 229940124834 selective serotonin reuptake inhibitor Drugs 0.000 title abstract 5
- 239000012896 selective serotonin reuptake inhibitor Substances 0.000 title abstract 5
- 238000009472 formulation Methods 0.000 title abstract 4
- 238000013270 controlled release Methods 0.000 title abstract 3
- 229960004038 fluvoxamine Drugs 0.000 title abstract 2
- CJOFXWAVKWHTFT-XSFVSMFZSA-N fluvoxamine Chemical compound COCCCC\C(=N/OCCN)C1=CC=C(C(F)(F)F)C=C1 CJOFXWAVKWHTFT-XSFVSMFZSA-N 0.000 title abstract 2
- 201000010099 disease Diseases 0.000 title 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 title 1
- 238000000034 method Methods 0.000 title 1
- 239000002245 particle Substances 0.000 abstract 2
- 150000003839 salts Chemical class 0.000 abstract 2
- 238000000338 in vitro Methods 0.000 abstract 1
- 238000001727 in vivo Methods 0.000 abstract 1
- 239000008185 minitablet Substances 0.000 abstract 1
- 239000008188 pellet Substances 0.000 abstract 1
- 229920000642 polymer Polymers 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
- A61K31/137—Arylalkylamines, e.g. amphetamine, epinephrine, salbutamol, ephedrine or methadone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/15—Oximes (>C=N—O—); Hydrazines (>N—N<); Hydrazones (>N—N=) ; Imines (C—N=C)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/167—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction with an outer layer or coating comprising drug; with chemically bound drugs or non-active substances on their surface
- A61K9/1676—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction with an outer layer or coating comprising drug; with chemically bound drugs or non-active substances on their surface having a drug-free core with discrete complete coating layer containing drug
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/5073—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings
- A61K9/5078—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings with drug-free core
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/5084—Mixtures of one or more drugs in different galenical forms, at least one of which being granules, microcapsules or (coated) microparticles according to A61K9/16 or A61K9/50, e.g. for obtaining a specific release pattern or for combining different drugs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
Abstract
Мультичастинкова композиція контрольованого вивільнення селективного інгібітору зворотного захоплення серотоніну (SSRI) для перорального введення, яка включає частинки, що складаються з ядра, яке містить флувоксамін або його фармацевтично прийнятну сіль, і покриття, що забезпечує контрольоване вивільнення вказаного SSRI протягом періоду часу не менше, ніж приблизно 12 годин, після перорального введення. Композиція придатна для одноразового або дворазового прийому на день. Композиція може містити суміш двох або більше видів частинок, гранул або міні-таблеток, які мають різні характеристики вивільнення in vitro та/або in vivo.
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US13502899P | 1999-05-20 | 1999-05-20 | |
IE19990406A IE990406A1 (en) | 1999-05-20 | 1999-05-20 | Multiparticulate controlled release selective serotonin reuptake inhibitor formulations. |
PCT/IE2000/000060 WO2000071099A1 (en) | 1999-05-20 | 2000-05-10 | Multiparticulate controlled release selective serotonin reuptake inhibitor formulations |
Publications (1)
Publication Number | Publication Date |
---|---|
UA74335C2 true UA74335C2 (uk) | 2005-12-15 |
Family
ID=27620490
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
UA2001128821A UA74335C2 (uk) | 1999-05-20 | 2000-05-10 | Мультичастинкова композиція контрольованого вивільнення флувоксаміну та спосіб лікування станів, які лікуються за допомогою селективних інгібіторів зворотного захоплення серотоніну |
Country Status (4)
Country | Link |
---|---|
US (2) | US7465462B1 (uk) |
IE (1) | IE990406A1 (uk) |
UA (1) | UA74335C2 (uk) |
ZA (1) | ZA200110401B (uk) |
Families Citing this family (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
IE990406A1 (en) * | 1999-05-20 | 2000-12-27 | Elan Corp Plc | Multiparticulate controlled release selective serotonin reuptake inhibitor formulations. |
US8158149B2 (en) * | 2004-05-12 | 2012-04-17 | Chelsea Therapeutics, Inc. | Threo-DOPS controlled release formulation |
US20060105036A1 (en) | 2003-05-12 | 2006-05-18 | Stephen Peroutka | Threo-dops controlled release formulation |
CA2598273A1 (en) * | 2005-02-17 | 2006-08-24 | Merck & Co., Inc. | Method of treating atherosclerosis, dyslipidemias and related conditions |
US20080081067A1 (en) * | 2006-10-03 | 2008-04-03 | Gupta Manishkumar | Sustained release pharmaceutical compositions of venlafaxine and process for preparation thereof |
WO2010138439A1 (en) * | 2009-05-28 | 2010-12-02 | Aptapharma, Inc. | Multiparticulate controlled-release selective serotonin reuptake inhibitor formulations |
CN102579406A (zh) * | 2012-01-17 | 2012-07-18 | 广州科的信医药技术有限公司 | 一种盐酸氯米帕明缓释胶囊及其制备方法 |
Family Cites Families (20)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
NL7503310A (nl) | 1975-03-20 | 1976-09-22 | Philips Nv | Verbindingen met antidepressieve werking. |
US4851228A (en) * | 1984-06-20 | 1989-07-25 | Merck & Co., Inc. | Multiparticulate controlled porosity osmotic |
US5271946A (en) * | 1988-04-20 | 1993-12-21 | Asta Pharma Aktiengesellschaft | Controlled release azelastine-containing pharmaceutical compositions |
US5133974A (en) | 1989-05-05 | 1992-07-28 | Kv Pharmaceutical Company | Extended release pharmaceutical formulations |
US5958458A (en) * | 1994-06-15 | 1999-09-28 | Dumex-Alpharma A/S | Pharmaceutical multiple unit particulate formulation in the form of coated cores |
GB9514842D0 (en) | 1995-07-20 | 1995-09-20 | Smithkline Beecham Plc | Novel formulation |
PE57198A1 (es) | 1996-03-25 | 1998-10-10 | American Home Prod | Formula de liberacion prolongada |
HRP970493A2 (en) * | 1996-09-23 | 1998-08-31 | Wienman E. Phlips | Oral delayed immediate release medical formulation and method for preparing the same |
US5776969A (en) * | 1997-02-27 | 1998-07-07 | Eli Lilly And Company | Treatment of sleep disorders |
US5910319A (en) | 1997-05-29 | 1999-06-08 | Eli Lilly And Company | Fluoxetine enteric pellets and methods for their preparation and use |
PL337799A1 (en) | 1997-07-01 | 2000-09-11 | Pfizer Prod Inc | Sertralin dosage forms of retarded release |
IL152330A0 (en) | 1997-07-01 | 2003-05-29 | Pfizer | Sertraline salts and sustained-release dosage forms of sertraline |
US6599529B1 (en) * | 1997-09-11 | 2003-07-29 | Nycomed Danmark A/S | Modified release multiple-units compositions of non-steroid anti-inflammatory drug substances (NSAIDs) |
US6066339A (en) * | 1997-10-17 | 2000-05-23 | Elan Corporation, Plc | Oral morphine multiparticulate formulation |
US5948440A (en) * | 1997-12-17 | 1999-09-07 | Ranbaxy Laboratories Limited | Modified release matrix formulation of cefaclor and cephalexin |
IE990406A1 (en) * | 1999-05-20 | 2000-12-27 | Elan Corp Plc | Multiparticulate controlled release selective serotonin reuptake inhibitor formulations. |
US6080736A (en) * | 1999-10-27 | 2000-06-27 | Janus Pharmaceuticals, Inc. | Methods and compositions for treating and preventing anxiety and anxiety disorders using optically pure (R) tofisopam |
US6458384B2 (en) * | 2000-02-23 | 2002-10-01 | Impetus Ag | Pharmaceutical with predetermined activity profile |
US6306436B1 (en) * | 2000-04-28 | 2001-10-23 | Teva Pharmaceuticals Usa, Inc. | Stabilized, acid-free formulation for sustained release of bupropion hydrochloride |
US6482440B2 (en) * | 2000-09-21 | 2002-11-19 | Phase 2 Discovery, Inc. | Long acting antidepressant microparticles |
-
1999
- 1999-05-20 IE IE19990406A patent/IE990406A1/en not_active IP Right Cessation
-
2000
- 2000-05-10 US US09/744,169 patent/US7465462B1/en not_active Expired - Fee Related
- 2000-05-10 UA UA2001128821A patent/UA74335C2/uk unknown
-
2001
- 2001-12-19 ZA ZA200110401A patent/ZA200110401B/xx unknown
-
2008
- 2008-05-02 US US12/114,483 patent/US20080206335A1/en not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
US7465462B1 (en) | 2008-12-16 |
IE990406A1 (en) | 2000-12-27 |
US20080206335A1 (en) | 2008-08-28 |
ZA200110401B (en) | 2003-03-03 |
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