UA66932C2 - Complex of eletriptan and sulphobutylether-beta-cyclodextrin, pharmaceutical composition, method for their manufacture and method for treating migraine - Google Patents

Complex of eletriptan and sulphobutylether-beta-cyclodextrin, pharmaceutical composition, method for their manufacture and method for treating migraine

Info

Publication number
UA66932C2
UA66932C2 UA2001129200A UA2001129200A UA66932C2 UA 66932 C2 UA66932 C2 UA 66932C2 UA 2001129200 A UA2001129200 A UA 2001129200A UA 2001129200 A UA2001129200 A UA 2001129200A UA 66932 C2 UA66932 C2 UA 66932C2
Authority
UA
Ukraine
Prior art keywords
complex
sulphobutylether
eletriptan
cyclodextrin
beta
Prior art date
Application number
UA2001129200A
Other languages
English (en)
Original Assignee
Pfizer
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer filed Critical Pfizer
Publication of UA66932C2 publication Critical patent/UA66932C2/xx

Links

Classifications

    • BPERFORMING OPERATIONS; TRANSPORTING
    • B82NANOTECHNOLOGY
    • B82YSPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES
    • B82Y5/00Nanobiotechnology or nanomedicine, e.g. protein engineering or drug delivery
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/69Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit
    • A61K47/6949Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit inclusion complexes, e.g. clathrates, cavitates or fullerenes
    • A61K47/6951Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit inclusion complexes, e.g. clathrates, cavitates or fullerenes using cyclodextrin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/08Drugs for disorders of the alimentary tract or the digestive system for nausea, cinetosis or vertigo; Antiemetics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/04Centrally acting analgesics, e.g. opioids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/06Antimigraine agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/18Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/22Anxiolytics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/24Antidepressants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/30Drugs for disorders of the nervous system for treating abuse or dependence
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/04Anorexiants; Antiobesity agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/12Antihypertensives
UA2001129200A 1999-06-29 2000-06-02 Complex of eletriptan and sulphobutylether-beta-cyclodextrin, pharmaceutical composition, method for their manufacture and method for treating migraine UA66932C2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB9915231.6A GB9915231D0 (en) 1999-06-29 1999-06-29 Pharmaceutical complex
PCT/IB2000/000746 WO2001000243A1 (fr) 1999-06-29 2000-06-02 Complexe pharmaceutique

Publications (1)

Publication Number Publication Date
UA66932C2 true UA66932C2 (en) 2004-06-15

Family

ID=10856302

Family Applications (1)

Application Number Title Priority Date Filing Date
UA2001129200A UA66932C2 (en) 1999-06-29 2000-06-02 Complex of eletriptan and sulphobutylether-beta-cyclodextrin, pharmaceutical composition, method for their manufacture and method for treating migraine

Country Status (44)

Country Link
US (2) US6713461B1 (fr)
EP (1) EP1189640B1 (fr)
JP (2) JP4454900B2 (fr)
KR (1) KR20020015067A (fr)
CN (1) CN1198654C (fr)
AP (1) AP2001002369A0 (fr)
AR (1) AR033337A1 (fr)
AT (1) ATE290884T1 (fr)
AU (1) AU770169B2 (fr)
BG (1) BG106151A (fr)
BR (1) BR0011845A (fr)
CA (1) CA2376847C (fr)
CO (1) CO5170494A1 (fr)
CZ (1) CZ20014572A3 (fr)
DE (1) DE60018744T2 (fr)
DZ (1) DZ3320A1 (fr)
EA (1) EA003908B1 (fr)
EC (1) ECSP003551A (fr)
EE (1) EE200100697A (fr)
ES (1) ES2235879T3 (fr)
GB (1) GB9915231D0 (fr)
GE (1) GEP20043377B (fr)
GT (1) GT200000102A (fr)
HR (1) HRP20010951A2 (fr)
HU (1) HUP0201629A3 (fr)
IL (1) IL146341A0 (fr)
IS (1) IS6163A (fr)
MA (1) MA26801A1 (fr)
MX (1) MXPA01013274A (fr)
NO (1) NO20016430L (fr)
NZ (1) NZ515235A (fr)
OA (1) OA11964A (fr)
PA (1) PA8496801A1 (fr)
PE (1) PE20010346A1 (fr)
PL (1) PL352902A1 (fr)
SK (1) SK18932001A3 (fr)
SV (1) SV2002000112A (fr)
TN (1) TNSN00142A1 (fr)
TR (1) TR200103827T2 (fr)
UA (1) UA66932C2 (fr)
UY (1) UY26224A1 (fr)
WO (1) WO2001000243A1 (fr)
YU (1) YU87501A (fr)
ZA (1) ZA200110454B (fr)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9915231D0 (en) * 1999-06-29 1999-09-01 Pfizer Ltd Pharmaceutical complex
US7115587B2 (en) * 2002-08-20 2006-10-03 Bristol-Myers Squibb Company Aripiprazole complex formulation and method
GB0329918D0 (en) * 2003-12-24 2004-01-28 West Pharm Serv Drug Res Ltd Intranasal compositions
CN1296391C (zh) * 2004-03-04 2007-01-24 中国人民解放军第二军医大学 氟代羧烷基环糊精醚类化合物及其制备方法和应用
GB0613925D0 (en) 2006-07-13 2006-08-23 Unilever Plc Improvements relating to nanodispersions
CN101957330B (zh) * 2010-06-12 2013-10-09 南京巨环医药科技开发有限公司 磺丁基倍他环糊精含量的测定方法
WO2017122161A1 (fr) * 2016-01-15 2017-07-20 Cadila Healthcare Limited Composition intranasale comprenant des agonistes de récepteur 5ht1b/1d
US20190224171A1 (en) * 2018-01-22 2019-07-25 Insys Development Company, Inc. Liquid rizatriptan compositions

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5376645A (en) * 1990-01-23 1994-12-27 University Of Kansas Derivatives of cyclodextrins exhibiting enhanced aqueous solubility and the use thereof
KR0166088B1 (ko) * 1990-01-23 1999-01-15 . 수용해도가 증가된 시클로덱스트린 유도체 및 이의 용도
HU210921B (en) 1990-03-28 1995-09-28 Chinoin Gyogyszer Es Vegyeszet Process for preparing inclusion complexes of n-ethoxycarbonyl-3-morpholino-sydnonimine formed with cyclodextrines and pharmaceutical compositions containing them
HU212730B (en) 1990-03-28 1996-10-28 Chinoin Gyogyszer Es Vegyeszet Process for producing inclusion complexes of cyclodextrine or its derivative and 3-morpholino-sydnonimine or its salt or its tautomer and pharmaceutical compositions containing them
AU651637B2 (en) 1990-10-15 1994-07-28 Pfizer Inc. Indole derivatives
EP0687174B1 (fr) 1993-03-05 2001-06-13 Hexal Ag Complexes cristallins d'insertion de cyclodextrine de l'hydrochlorure de ranitidine, et leur procede de preparation
MX9504664A (es) 1994-03-07 1997-05-31 Dow Chemical Co Conjugados de dendrimeros bioactivos y/o dirigidos.
GB9417310D0 (en) 1994-08-27 1994-10-19 Pfizer Ltd Therapeutic agents
CN1230123A (zh) 1996-07-11 1999-09-29 荷兰发马克有限公司 含碱性药物的酸加成盐的药物组合物
US5998462A (en) 1996-12-16 1999-12-07 Allelix Biopharmaceuticals Inc. 5-alkyl indole compounds
GB9704498D0 (en) 1997-03-05 1997-04-23 Glaxo Wellcome Spa Chemical compound
EA002174B1 (ru) 1997-07-03 2002-02-28 Пфайзер Инк. Фармацевтические композиции, содержащие гемисульфат элетриптана и кофеин
GB9816556D0 (en) * 1998-07-30 1998-09-30 Pfizer Ltd Therapy
GB9915231D0 (en) * 1999-06-29 1999-09-01 Pfizer Ltd Pharmaceutical complex

Also Published As

Publication number Publication date
WO2001000243A1 (fr) 2001-01-04
CA2376847C (fr) 2007-09-25
NZ515235A (en) 2003-08-29
EP1189640A1 (fr) 2002-03-27
TNSN00142A1 (fr) 2005-11-10
MA26801A1 (fr) 2004-12-20
JP4454900B2 (ja) 2010-04-21
YU87501A (sh) 2004-05-12
EE200100697A (et) 2003-02-17
PA8496801A1 (es) 2002-02-21
PE20010346A1 (es) 2001-03-26
DZ3320A1 (fr) 2001-01-04
US20040186076A1 (en) 2004-09-23
AU770169B2 (en) 2004-02-12
PL352902A1 (en) 2003-09-22
NO20016430L (no) 2002-02-26
GT200000102A (es) 2001-12-14
BR0011845A (pt) 2002-03-05
OA11964A (en) 2006-04-17
GB9915231D0 (en) 1999-09-01
EP1189640B1 (fr) 2005-03-16
CA2376847A1 (fr) 2001-01-04
CZ20014572A3 (cs) 2002-08-14
BG106151A (en) 2002-05-31
MXPA01013274A (es) 2002-06-04
KR20020015067A (ko) 2002-02-27
EA003908B1 (ru) 2003-10-30
TR200103827T2 (tr) 2002-05-21
DE60018744D1 (de) 2005-04-21
ATE290884T1 (de) 2005-04-15
AP2001002369A0 (en) 2001-12-31
IS6163A (is) 2001-11-16
SV2002000112A (es) 2002-02-05
AR033337A1 (es) 2003-12-17
AU4774100A (en) 2001-01-31
HUP0201629A2 (hu) 2003-03-28
NO20016430D0 (no) 2001-12-28
UY26224A1 (es) 2001-01-31
HRP20010951A2 (en) 2005-04-30
ES2235879T3 (es) 2005-07-16
CN1359303A (zh) 2002-07-17
GEP20043377B (en) 2004-04-13
ZA200110454B (en) 2002-12-20
ECSP003551A (es) 2002-01-25
JP2006257091A (ja) 2006-09-28
SK18932001A3 (sk) 2002-09-10
DE60018744T2 (de) 2006-05-18
CO5170494A1 (es) 2002-06-27
EA200101106A1 (ru) 2002-06-27
JP2003503364A (ja) 2003-01-28
CN1198654C (zh) 2005-04-27
HUP0201629A3 (en) 2003-11-28
US6713461B1 (en) 2004-03-30
IL146341A0 (en) 2002-07-25

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