UA113876C2

UA113876C2 - Похідні карбамат/сечовини

Похідні карбамат/сечовини Download PDF

Info

Publication number: UA113876C2
Authority: UA; Ukraine
Prior art keywords: carboxylate; oxo; compound; dihydropyridazin; piperidin
Prior art date: 2012-07-20

Application number

UAA201412965A

Other languages

English (en)

Ukrainian (uk)

Priority date

2012-07-20

Filing date

2013-07-18

Publication date

2017-03-27

2013-07-18 Application filed filed Critical

2013-07-18 Priority claimed from PCT/IB2013/055916 external-priority patent/WO2014013469A1/en

2017-03-27 Publication of UA113876C2 publication Critical patent/UA113876C2/uk

Links

KXDHJXZQYSOELW-UHFFFAOYSA-M Carbamate Chemical compound NC([O-])=O KXDHJXZQYSOELW-UHFFFAOYSA-M 0.000 title 1
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-1 1-(6-oxo-1,6-dihydropyridazin-3-yl)piperidin-4-yl Chemical group 0.000 claims description 56
HRHRDQYFKULMGY-UHFFFAOYSA-N 4-cyclobutylpiperazine-1-carboxylic acid Chemical compound C1CN(C(=O)O)CCN1C1CCC1 HRHRDQYFKULMGY-UHFFFAOYSA-N 0.000 claims description 56
208000035475 disorder Diseases 0.000 claims description 56
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VZCYOOQTPOCHFL-OWOJBTEDSA-N Fumaric acid Chemical compound OC(=O)\C=C\C(O)=O VZCYOOQTPOCHFL-OWOJBTEDSA-N 0.000 claims description 31
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150000002367 halogens Chemical class 0.000 claims description 29
KRKNYBCHXYNGOX-UHFFFAOYSA-N citric acid Chemical group OC(=O)CC(O)(C(O)=O)CC(O)=O KRKNYBCHXYNGOX-UHFFFAOYSA-N 0.000 claims description 28
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ZSRNFLXZSHHQPI-UHFFFAOYSA-N piperidin-4-yl 4-cyclobutylpiperazine-1-carboxylate Chemical compound C1CN(C2CCC2)CCN1C(=O)OC1CCNCC1 ZSRNFLXZSHHQPI-UHFFFAOYSA-N 0.000 claims description 20
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BVUJMFFRMZRNAT-UHFFFAOYSA-N [1-(1-methyl-6-oxopyridazin-3-yl)piperidin-4-yl] 4-cyclobutylpiperazine-1-carboxylate Chemical compound C1=CC(=O)N(C)N=C1N1CCC(OC(=O)N2CCN(CC2)C2CCC2)CC1 BVUJMFFRMZRNAT-UHFFFAOYSA-N 0.000 claims description 14
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