TWM610166U - Microcapsule structure - Google Patents

Abstract

This creation is a kind of microcapsule structure. The microcapsule structure is composed of kiesonic acid as the shell layer, and its inner core is coated with essential oils and vegetable oils as active ingredients. The essential oils include Lavender Spike essential oil, Melaleuca alba essential oil, There are four essential oils: rock rose essential oil and permanent flower essential oil, and the vegetable oil includes three kinds of vegetable oils: Gotu Kola oil, St. John's Wort oil and Qiongya Begonia oil. With its microcapsule structure, the above-mentioned essential oils and vegetable oils as effective active ingredients can be coated in it, prolonging the storage time, and the microcapsule structure has a slow release effect, which can extend the time for the essential oils and vegetable oils to act on the skin surface. Essential oils and vegetable oils have the effects of promoting collagen proliferation, antibacterial and anti-inflammatory effects.

Description

Microcapsule structure

This creation is about a microcapsule structure, especially a microcapsule structure coated with essential oils and vegetable oils as effective active ingredients that can effectively promote collagen proliferation, help cell regeneration, antibacterial and anti-inflammatory.

Essential oil is a kind of aromatic oil extracted from flowers and plants. There are many flowers and plants in nature, but not every plant contains essential oils. Extracting those plants that are rich in essential oils and has deep curative effects will get very pure Essential oils. As for the extracted parts, the essential oils extracted from different parts of the plant including flowers, roots, stems, leaves, trees, barks, and fruits have different effects.

As early as thousands of years ago, people have discovered that essential oils have specific medical effects, but it was not until the last Shi Ji that people did research on this aromatic substance, and it was possible to confirm this concentrated aromatic substance extracted from plants. , Does have clinical medical utility. Specifically, essential oils can promote skin regeneration, reduce physical and mental stress, and at the same time have the effect of eliminating toxins in the body, and can relax our spirits.

There are many advantages to using essential oils for treatment, care and maintenance. The main reason is that essential oils can interact with the body’s immune system, which is different from the process of chemical synthesis and processing. Therefore, compared with chemical drugs, essential oils have less side effects and are harmful to the human body. The therapeutic effect of the drug is milder.

Essential oils generally have certain antiseptic properties, as well as antibacterial and anti-inflammatory properties. At the same time, essential oils are extremely volatile. If placed directly in the air or exposed to sunlight, essential oils will evaporate quickly. Therefore, when storing essential oils, you must store essential oils in a dry and cool place. At the same time, essential oils are insoluble in water. It can be dissolved in liquids such as pure alcohol, fat and oil.

The mechanism of essential oil's antibacterial activity is very complicated, and until now, it has not been fully understood. It is generally believed to be related to the hydrophilic and hydrophobic molecules in the chemical composition of essential oils. Essential oils are composed of post-type compounds, which are soluble in lipids and other media, which can interfere with the enzyme activity of bacteria, such as the activity of respiration. In the composition of essential oils, in single-layer compounds, the functional groups contained in the chemical structural formula and the hydrophobicity and hydrophilicity of the hydrocarbon skeleton will all affect the antibacterial properties.

From the above content, it can be known that the essential oil itself is extremely volatile, so it needs to be stored in a specific way, such as in a sealed bottle. In addition, the drugs applied to human skin are mostly stored in bottles, etc. However, after opening, the drugs will inevitably come into contact with the air, thus increasing the chance of oxidative deterioration. After being applied to the skin, the drug will gradually deteriorate due to exposure to the external environment, and then lose its effectiveness. This shortens the time of action of the drug, and often requires replenishment, which is more inconvenient to use.

At present, volatile drugs applied to the skin on the market cannot provide a design that is not easy to deteriorate and has a longer effect time. Therefore, in view of the above-mentioned shortcomings, the creator of this book developed this creation after intensive research.

In view of this, the main purpose of this creation is to provide a microcapsule structure, which mainly uses kesonic acid as the shell layer of the microcapsule, and uses a variety of essential oils and a variety of vegetable oils as the active ingredients. It is formed by coating the microcapsules as the core. In this way, the above-mentioned active ingredients can be coated to ensure that the active ingredients are not affected by other external environments, resulting in qualitative changes. In addition, through its microcapsule structure, the above-mentioned essential oils and vegetable oils as effective active ingredients can be coated in it, prolonging the storage time, and the microcapsule structure has the effect of slow release, so that users can use the above microcapsule structure At this time, the essential oils and vegetable oils in the core of the microcapsules as effective active ingredients are slowly released to contact with the skin, prolonging the time for the essential oils and vegetable oils to act on the skin surface, thereby obtaining good antibacterial, anti-inflammatory and therapeutic effects.

There are four kinds of essential oils used in the microcapsule structure of this creation, while three kinds of vegetable oils are used. Both essential oils and vegetable oils have the effects of promoting collagen proliferation, helping cell regeneration, antibacterial and anti-inflammatory effects, and can promote epidermal cell regeneration and make The wound tissue fluid quickly converges and helps the wound to regenerate and heal. According to the specific use ratio and the type of specific essential oils and vegetable oils, after further blending the essential oils and vegetable oils, it has a better synergistic effect, which can accelerate wound repair and is not easy to leave scars. .

There are four kinds of essential oils used in this creation: lavender essential oil, melaleuca essential oil, rock rose essential oil, and permanent flower essential oil; and three kinds of vegetable oils: Gotu Kola oil, St. John's Wort oil and Qiongya Begonia oil. The effects of various essential oils and vegetable oils are introduced as follows.

Lavandula Spike (Lavandula latifolia L.Medicus), the main ingredients are monoterpene pine oil terpene, campene, β-bisabolene and monoterpene alcohol. It is mainly produced in Bulgaria and contains ketones with strong mucosal regeneration. The substance can resist mucosal inflammation; when used in severe burns, it can enhance the cell defense function, resist mucosal inflammation, and has a good analgesic effect. It is suitable for wound care for first-degree severe burns to help wound regeneration and healing.

Niaouli (scientific name Melaleuca quinquenervia), the main ingredients are sesame oil, alpha pine oil terpene, beta pine oil terpene, linalool and quinquenerol, the main production area is commonly found in Australia And New Caledonia, it has the effect of antibacterial and promoting wound scabs, can promote blood circulation, increase the strength of white blood cell antibodies, has a strong healing power, and is also an anti-inflammatory and antibacterial component of a variety of drugs.

Cistus (Scientific name Cistus ladaniferus L.), whose main ingredients are alpha pine oil terpene ketones sesquiterpenes and monoterpene alcohols, are mainly produced in Portugal and Spain. It has potent hemostatic and wound healing effects. Arterial inflammation or internal and external bleeding can help stop the bleeding. In addition, it has the effect of quickly converging mucus in the wound of mucosal tissue or when there is too much mucus in the wound.

Immortelle (Scientific name Helichrysum italicum G.Don), the main ingredients are β-diketone, Italian ketone, β-syringe hydrocarbon and neryl acetate. The main production area is common in Corsica, which has a good promotion of cells and mucous membranes. It is regenerative and has a good effect of resolving stasis and swelling. It can improve blood stasis, hematoma and other problems; it can also help the skin heal from scars, acne and eczema.

Gotu Kola (Asiatic Pennywort, scientific name Centella asiatica), the main components of which are triterpene saponins, polyacetylene alkenes (such as madecassoside, asiatic acid, madecassoside and asiatic saponins) and volatile oils, which are found in tropical and subtropical regions. It is widely distributed in the region. Clinical studies have found that the asiaticoside in Gotu Kola can change the ultrastructure of fibroblasts, inhibit the abnormal proliferation of protein, reduce the proliferation of fibroblasts when protein synthesis and secretion functions are greatly weakened, and avoid tissue skin fibers. Phenomena such as roughening (roughening). Among them, asiaticoside can effectively repair skin scars, reduce the activity of scar material synthase, and increase the protein expression rate of inhibiting its synthase to reduce scar hyperplasia; in addition, the hydroxyl contained in Gotu Kola root Asiatic acid, asiatic acid, madecassoside and asiaticoside can also significantly inhibit the proliferation of fibroblasts in the process of wound repair, and have the effect of promoting collagen proliferation.

St. John Wort (Scientific name Hypericum perforatum), namely Chinese Hypericum perforatum or Hypericum perforatum, the main ingredient is hypericin, can be used in the treatment of trauma (such as trauma or burn Injuries) and neuralgia. It also has the effects of anti-depression, anti-depression, soothing pain, relaxing muscles, promoting blood circulation and inhibiting inflammation.

Indiapoon Beatyleaf (Indiapoon Beatyleaf, scientific name Calophyllum inophyllum L.), also known as Enofilum, is mainly composed of thymol, terpenes, alcohols, aromatic acids and pyranocoumarin derivatives, which have a powerful analgesic effect It has the anti-inflammatory effect to promote scar repair. It is suitable for inflamed skin lesions, pimples, acne and difficult-to-heal wounds. It can help promote wound healing, eliminate burns and scars created after surgery, and is used to treat ulcers and serious wounds.

The advantages of this creation: The above-mentioned wounds are wounds caused by surgery or trauma, such as contusions, open suture wounds, etc., which are often difficult to take care of. If the appearance of the wound is not properly cleaned, it is easy to cause wound infection, and at the same time, this kind of wound healing speed Slow, the general care mostly only uses saline to clean the wound and bandaged with gauze; in addition, large-area wounds usually have more tissue fluid, and when the dressing is changed, it is easier to cause pain due to pulling and re-injury the wound, thereby delaying the wound The speed of healing. Therefore, by directly applying the microcapsule structure of this creation to the wound, the wound tissue fluid can quickly converge, and the epidermal cells of the wound can be regenerated quickly, so that the wound can heal quickly; and the antibacterial effect of essential oils and vegetable oils can prevent The wound is worsened by bacterial infection, reducing the chance of infection.

1: Microcapsule structure

2: shell

3: core

4: Spike lavender essential oil

5: Green Flower White Melaleuca Essential Oil

6: Rock rose essential oil

7: permanent flower essential oil

8: Gotu Kola oil

9: St. John's Wort Oil

10: Qiongya Begonia Oil

Figure 1 is a three-dimensional perspective schematic diagram of the microcapsule structure created; Figure 2 is a perspective cross-sectional schematic diagram of the microcapsule structure created; Figure 3 is a front cross-sectional schematic diagram of the microcapsule structure created.

The microcapsule structure of this creation can be fully understood by the following description of the implementation mode, so that those who are familiar with the art can complete the microcapsule structure described in this creation; however, the implementation of this creation cannot be achieved by the following implementation methods. Restricting its implementation type, those who are familiar with this technique can still deduce other implementation methods based on the spirit of the disclosed implementation methods, and these implementation methods should fall within the scope of this creation.

In order to have a more complete and clear disclosure of the technical content, the purpose of creation and the effects achieved in this creation, we will explain them in detail below, and please refer to the disclosed diagrams and figure numbers.

Please refer to Figure 1, Figure 2, and Figure 3, which are respectively a three-dimensional perspective schematic diagram, a three-dimensional cross-sectional schematic diagram, and a front cross-sectional schematic diagram of the microcapsule structure created in this order. The microcapsule structure 1 of the present invention includes: a shell layer 2 that forms a hollow spherical structure; and a core 3 that is the hollow spherical structure formed by the shell layer 2 Defined by the internal space.

Wherein, the shell layer 2 is composed of Chitosonic Acid (CA, also known as Chitosonic Acid). The molecular size of Chitosonic Acid is only 50-200nm, which can penetrate the stratum corneum and enter the dermis. The macromolecules form a 3D water-locking layer on the surface of the skin, and the small kesonic acid molecules can combine with water molecules to form nano-water microspheres, which tightly wrap the water molecules and effective ingredients and penetrate into the dermis. Fill the skin with moisture from the inside to the outside, so that the active ingredients can be used to the extreme; in addition, when kesononic acid is used as the carrier of various active ingredients, kesononic acid can slowly release its various active ingredients and prolong the activity of the active ingredients It also has excellent anti-free radical ability and antibacterial effect, and its antibacterial effect is close to 100%, so it is better to use kesononic acid as a carrier system for various active ingredients.

The core 3 contains a plurality of essential oils and vegetable oils as effective active ingredients that have the functions of promoting collagen proliferation, helping cell regeneration, antibacterial and anti-inflammatory; the essential oils are Lavender Spike essential oil 4 and Melaleuca alba essential oil 5 Four essential oils, namely, Rock Rose essential oil 6 and permanent flower essential oil 7, and the vegetable oils are respectively three medicinal vegetable oils including Gotu Kola oil 8, St. John’s Wort oil 9, and Qiongya Begonia oil 10.

In one embodiment, the preparation steps of the microcapsule structure 1 of the present creation are as follows:

Step 1. Combine four essential oils such as Spikeflower Lavender Essential Oil 4, Green Flower White Melaleuca Essential Oil 5, Rock Rose Essential Oil 6, and Permanent Flower Essential Oil 7 with Gotu Kola oil 8, St. John's Wort Oil 9 and Qiongya Begonia Oil 10 and other three vegetable oils. The specific ratio is well blended to form a compound combination essential oil;

Step 2. Add kesononic acid to the compound essential oil prepared in step 1, and add sodium tripolyphosphate to form a mixture.

Step 3. Pour the mixture prepared in step 2 into a digital homogenizer, and coat the compound essential oil inside the kiesonic acid by an ion exchange method to form the microcapsule structure 1.

In one embodiment, the mixing ratio of the Gotu Kola oil 8, the St. John's Wort oil 9 and the Qiongya Begonia oil 10 is 2:3:1 in order by weight; for example, the Gotu Kola oil When the total weight of oil 8, the St. John's Wort oil 9 and the Qiongya Begonia oil 10 is 100 g, the actual weights are 33 g, 50 g, and 17 g in order.

In one embodiment, the four essential oils including the Lavender Spike essential oil 4, the Melaleuca alba essential oil 5, the Rock Rose essential oil 6, and the Eternal Flower essential oil 7 are based on the Gotu Kola oil 8, the 8% (in weight percentage) of the total weight of the St. John’s Wort Oil 9 and the Qiongya Begonia Oil 10 are mixed with them; for example, the Gotu Kola Oil 8, the St. John’s Wort Oil 9 and the Qiongya Begonia Oil 10 When the total weight of the three is 100g, the actual total weight of the lavender essential oil 4, the melaleuca virginiana essential oil 5, the rock rose essential oil 6 and the permanent flower essential oil 7 is 8g.

In one embodiment, the mixing ratios of the four essential oils, including the Lavender Spike essential oil 4, the Melaleuca alba essential oil 5, the Rock Rose essential oil 6, and the Eternal Flower essential oil 7, are in order by weight ratio. 4:3:2:2; for example, when the total weight of the four essential oils of lavender lavender 4, the melaleuca virginiana essential oil 5, the rock rose essential oil 6 and the permanent flower essential oil 7 is 8g, the actual weight depends on The order is 2.8g, 2.2g, 1.5g, 1.5g.

In one embodiment, in the microcapsule structure 1, the diameter of the shell layer 2 is between 80 and 300 nm; preferably, the diameter of the shell layer 2 is between 90 and 250 nm; more preferably In particular, the diameter of the shell layer 2 is between 100 nm and 200 nm.

In one embodiment, the rotation speed of the digital homogenizer is set to 5000 rpm, and the amount of sodium tripolyphosphate used is 0.5% (by weight percentage) of the total weight of the four essential oils and the three vegetable oils. Under the preparation parameters of 1% (by weight percentage) of the total weight of the four essential oils and the three kinds of vegetable oils, the microcapsule structure 1 prepared therefrom has a better package of 57.5%. Coverage rate.

In one embodiment, the microcapsule structure 1 can be applied to various dressings or external medicines in addition to being directly applied to wounds; when applied to various dressings, the microcapsule structure 1 has Slowly release the active ingredients contained in it, so it can reduce the number of dressing changes and speed up wound healing; and used in various external medicines, the drug type can be liquid, ointment, emulsion, cream, gel Gel (e.g. hydrogel) and other forms, but not limited to this.

The above are only part of the implementation of this creation, and are not intended to limit this creation. Those modified with slight changes based on the creative spirit and characteristics of this creation should also be included in the scope of this application.

In summary, this creative implementation can indeed achieve the expected use effect, and the specific structure disclosed by it has not been seen in similar products, nor has it been disclosed before the application. It is in full compliance with the provisions of the Patent Law. In accordance with the requirements, Yan filed an application for a new patent in accordance with the law, and asked for favors for examination and granted a patent.

1: Microcapsule structure

2: shell

3: core

4: Spike lavender essential oil

5: Green Flower White Melaleuca Essential Oil

6: Rock rose essential oil

7: permanent flower essential oil

8: Gotu Kola oil

9: St. John's Wort Oil

10: Qiongya Begonia Oil

Claims (4)

A microcapsule structure comprising: a shell layer forming a hollow spherical structure; and a core defined by the inner space of the hollow spherical structure, wherein the shell layer is formed by It is composed of Chitosonic Acid; the core contains a plurality of essential oils and a plurality of vegetable oils as effective active ingredients. The microcapsule structure according to claim 1, wherein the plurality of essential oils are lavender essential oil, melaleuca essential oil, rock rose essential oil, and permanent flower essential oil. The microcapsule structure according to claim 1, wherein the plurality of vegetable oils are Gotu Kola oil, St. John's Wort oil and Qiongya Begonia oil. The microcapsule structure according to claim 1, wherein the diameter of the shell layer is between 100 nm and 200 nm.

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