TWM498056U - Blood spin bowl - Google Patents

Description

Blood centrifugation

The present invention is a blood centrifuge, especially a centrifugal crucible having a collecting portion, which can be made into a small blood centrifuge, and has a larger main centrifugal portion, which can increase the internal blood volume, and has better The separation of blood components.

Conventional blood centrifugation is usually used to separate various components in the blood in a variety of forms. However, the conventional technique is to centrifuge blood to make a large blood centrifuge, and the blood centrifuge can usually be separated. Out of the ball and plasma, it is impossible to directly separate high-concentration platelet plasma and platelet-poor plasma, because the boundary between the two is less obvious. Moreover, the structure of the blood centrifuge is simple, and usually has a smooth outer shell and core. It is easy to generate turbulent flow during centrifugation, and it is impossible to accurately separate blood components.

If you want to directly separate high-concentration platelet plasma and platelet-poor plasma, you can usually use only a traditional centrifuge to place the blood in a centrifuge tube. After centrifugation, the syringe is inserted into the centrifuge tube and the collection form. It is collected manually, and red blood cells are more likely to be extracted during the extraction process, and high-concentration platelet plasma and platelet-poor plasma cannot be collected in large quantities.

In addition, when the conventional blood centrifuge is combined with an optical sensing instrument, the blood component cannot be accurately separated, and because of its large volume, the blood sample required is required to be large, and the components in the blood cannot be completely separated.

In order to solve the above problems, the purpose of this creation is to produce a blood centrifuge that can accurately separate blood components, and to achieve turbulence in the process in order to achieve miniaturization of the centrifuge device, reduce the need for blood samples, and centrifuge. Therefore, the present invention is a blood centrifuge, comprising: a casing having an opening at the top of the casing; a core, the core being disposed inside the casing, and a collecting portion at a center of a top surface of the core a central sleeve is formed at a central portion of the collecting portion, and a core portion is formed between the core and the outer casing, and the centrifugal portion is connected to the collecting portion; and a stator is disposed on the stator In the opening, the stator has an inlet vessel, an outlet vessel, and a seal set, the inlet vessel is coupled to the central cannula, the outlet vessel is coupled to the collection portion, and the gasket set secures the stator head to the Opening.

The main technical means of this creation is that the creation has a collection part, which can collect the centrifuged substances in advance, is more flexible in operation and use, and is not easily contaminated when collected, and has a high concentration.

The secondary technical means of the present invention is that the outer casing of the present invention has an upper shell portion, a lower shell portion and a bottom shell, and the joint portion of the upper shell portion and the lower shell portion extends outward to form a shell bevel. a top portion of the upper shell portion, the lower shell portion is connected to the bottom shell, and the core is stepped, the core having an upper core portion, a middle core portion and a lower core portion, the upper core portion being connected to the middle core portion Extending outwardly to form a first core inclined surface, the junction of the middle core portion and the lower core portion extending outward to form a second core inclined surface, the collecting portion is located at a top surface of the upper core portion, and the centrifugal portion is The second core inclined surface, the middle core portion, the lower core portion, the outer shell slope surface and the lower shell portion form a main centrifugal portion, the stepped core and the bell-shaped outer casing, when the creation is made into a small centrifugal crucible At the same time, it can have a larger main centrifugal part, which can increase the internal blood volume, and can accurately reach the blood component separation state during centrifugation, and the outer surface of the outer shell can block the heavier blood substance and let the blood The lighter component of the liquid rises along the slope of the outer casing and has a better separation of blood components.

Compared with the conventional blood centrifuge, this creation has a collection part or a stepped core and a bell-shaped outer casing, so that the creation can be made into a miniaturization and more accurately separate the blood components. With the use of centrifuges, it is even possible to directly and accurately collect high-concentration platelet plasma and platelet-poor plasma. Conventional blood centrifugation is not possible because of its large size and simple structure.

10‧‧‧ blood centrifugation

1‧‧‧Shell

11‧‧‧ openings

2‧‧‧core

21‧‧‧ Collection Department

22‧‧‧Central casing

100‧‧‧ Centrifugal Department

3‧‧‧ 静子头

31‧‧‧Into the blood vessels

311‧‧‧Central tube

32‧‧‧Vascular

33‧‧‧Sealing pad set

12‧‧‧Upper shell

13‧‧‧ Lower shell

14‧‧‧ bottom case

15‧‧‧Shell bevel

23‧‧‧The Ministry of Nuclear Affairs

24‧‧‧Nuclear Department

25‧‧‧The Ministry of Nuclear Affairs

26‧‧‧First core bevel

27‧‧‧Second core bevel

1000‧‧‧Main Centrifugal Department

321‧‧‧Upper skirt

322‧‧‧Under skirt

331‧‧‧elastic gasket

332‧‧‧Fixed gasket

333‧‧‧ceramic seals

34‧‧‧Shell cover

35‧‧‧Fixed parts

20‧‧‧ fixture

30‧‧‧ Centrifuge

141‧‧‧ Groove

28‧‧‧Drainage trough

29‧‧‧Guide trough

40‧‧‧ Centrifugal seat

30‧‧‧ Centrifuge

20‧‧‧ fixture

60‧‧‧ optical sensing instruments

142‧‧‧Bumps

The first figure is a perspective view of the first embodiment of the present creation

The second figure is an exploded view of the second embodiment of the creation.

The third figure is a sectional view of the first embodiment of the present creation

The fourth figure is a partial view of the third embodiment of the creation.

The fifth figure is a perspective view of the fourth embodiment of the present creation

The sixth figure is a schematic diagram of the fifth embodiment of the present creation

The seventh figure is a partial cross-sectional view of the sixth embodiment of the present creation

First, please refer to the perspective view of the first embodiment of the first drawing, the exploded view of the second embodiment of the second drawing, and the cross-sectional view of the first embodiment of the third drawing. The three figures disclose that the system is a kind of The blood centrifuge 10 includes: a casing 1 having an opening 11 at the top of the casing 1; a core 2 disposed inside the casing 1 and having a collecting portion at the center of the top surface of the core 2 21, a central sleeve 22 is formed at the center of the collecting portion 21, and a core portion 22 is formed between the core 2 and the outer casing 1. The centrifugal portion 100 is connected to the collecting portion 21; a stator 3, the stator 3 is disposed in the opening 11, and the static The sub-head 3 has a blood inlet tube 31, an outflow blood vessel 32, and a gasket set 33. The blood inlet tube 31 is connected to the central sleeve 22, and the blood outlet tube 32 is connected to the collecting portion 21, and the gasket group 33 fixes the stator. The head 3 is at the opening 11.

The figure shows that the outer casing 1 is bell-shaped and has an upper casing portion 12, a lower casing portion 13 and a bottom casing 14. The upper casing portion 12 and the lower casing portion 13 extend outward to form a casing bevel 15 The opening 11 is formed at the top of the upper casing portion 12, the lower casing portion 13 is connected to the bottom casing 14, and the core 2 is stepped. The core 2 has an upper core portion 23 and a core portion 24. And a lower core portion 25, the upper core portion 23 and the central core portion 24 are extended outwardly to form a first core inclined surface 26, and the middle core portion 24 and the lower core portion 25 are extended outward to form a second core. a core inclined surface 27, the collecting portion 21 is located at a top surface of the upper core portion 23, and the centrifugal portion 100 is at the second core inclined surface 27, the middle core portion 24, the lower core portion 25, the outer shell inclined surface 15 and the lower shell The portion 13 forms a main centrifugal portion 1000.

In this embodiment, the blood vessel 32 is disposed outside the blood vessel 31, and the blood vessel 32 is connected to the collecting portion 21 to extend outward to form an upper skirt 321 and a lower skirt 322, and the upper skirt 321 and The lower skirt 322 is received in the collecting portion 21 and the opening 11, and the sealing group 33 fixes the stator 3 to the opening 11. The outer casing 1 can be made of a transparent material and can be matched with other optical sensing instruments.

Since the first embodiment has a stepped core 2 and a bell-shaped outer casing 1, when the present invention 10 is made into a small centrifugal crucible, it can have a larger main centrifugal portion 1000, which can increase the internal blood volume and centrifuge. At the same time, the blood component separation state can be accurately achieved, and the outer shell slope 15 can block the heavier blood substance from rising upward, and allow the lighter blood component to rise along the outer shell slope surface 15, thereby having a better blood component separation effect.

2 is an exploded view of the second embodiment of the present invention. The gasket assembly 33 of the present invention further includes an elastic gasket 331 , a fixed gasket 332 and a ceramic sealing ring 333 . The elastic sealing pad 331 is located at the uppermost layer, which can slow down and buffer the shaking of the outer casing 1 and the core 2 during centrifugation, and prevent the static head 3 from being damaged by friction with other parts of the present invention. The fixed sealing pad 332 is located on the second layer, and the fixing is fixed. The sealing pad 332 is combined with the elastic sealing pad 331 and is disposed to fix the edge of the elastic sealing pad 331 to maintain the edge of the elastic sealing pad 331 in a fixed shape. Finally, the ceramic sealing ring 333 is located at the The ceramic gasket 333 is fixed on the opening 11 and is in close contact with the fixed gasket 332. The ceramic gasket 333 is made of a wear-resistant material. When the outer casing 1 and the core 2 are rotated at a high speed, the ceramic gasket 333 is not easy. The high temperature is generated, and the durability is better, and it is not easy to be burst due to excessive pressure abnormality, and has a sealing effect. The end of the blood inlet tube 31 can be connected with a central tube 311, and the central tube 311 is along the middle. The sleeve 22 extends toward the bottom case 14, this design can slow the blood into the central sleeve 22, the sleeve 22 easily aroused turbulence at the center.

In addition, the figure also shows that a suitable cover 34 is provided at the appropriate position of the stator head 3. The cover 34 covers the gasket set 33, so that when the seal set 33 is damaged, the blood inside the creation 10 is ejected upward. The stator 3 is further provided with a fixing member 35. The fixing member 35 can fix the stator 3 to a clamp 20. When the present invention 10 is mounted on a centrifuge 30, the stator 3 It can be fixed by the jig 20 to rotate the outer casing 1 and the core 2 with respect to the stator 3 (please refer to the fifth figure).

Moreover, the center of the bottom case 14 projects downwardly relative to the central sleeve 22 to form a recess 141 which facilitates centralized recovery when blood is centrifuged.

In the first embodiment of the present invention, the core portion 23 and the upper shell portion 12 are left with each other. The air gap forms the centrifugal portion 100, and the lighter blood substance can be centrifuged and flowed to the collecting portion 21, and then guided and discharged through the upper skirt 321 and the lower skirt 322, or as disclosed in the second embodiment, The upper core portion 23 and the upper shell portion 12 are in close contact with each other, and the upper core portion 23 and the first core inclined surface 26 are provided with at least one drainage groove 28, and one end of the drainage groove 28 is connected to the main centrifugal portion 1000. The draining groove 28 is connected to the collecting portion 21 at the other end. The two embodiments of the present invention 10 can be combined with centrifuges of different preset pressures and different preset flow rates. The first embodiment of the present invention can be applied to a low flow rate. The centrifuge of the low pressure can be used in the centrifuge with higher flow rate and higher pressure, and the drainage groove 28 can avoid the disturbance of turbulent flow when collecting blood, and the function of the lower skirt 322 and The upper skirt 321 is the same.

Please refer to the third figure, which is a cross-sectional view of the first embodiment of the present invention. The figure shows that the blood from the blood vessel 31 enters the central sleeve 22 and then passes through the gap between the bottom shell 14 and the core 2 (belongs to centrifugation). The portion 100) enters the main centrifugal portion 1000, then rises into the collecting portion 21, and enters between the upper skirt 321 and the lower skirt 322 to discharge the blood vessel 32, and the outer surface of the outer shell 15 blocks the upward weight of the blood substance, and The lighter component of the blood rises along the bevel 15 of the outer casing.

Please refer to the fourth figure, which is a partial view of the third embodiment of the present invention. The bottom surface of the core 2 is further provided with a plurality of guiding grooves 29, and one end of the plurality of guiding grooves 29 is connected to the central casing. 22. The other ends of the plurality of guide grooves 29 are connected to the main centrifugal portion 1000. The structure of the present embodiment allows blood to enter the main centrifugal portion 1000 on average, thereby reducing turbulent flow inside the main centrifugal portion 1000.

Please refer to the fifth drawing, which is a perspective view of the fourth embodiment of the present invention. At least one protrusion 142 is disposed on the periphery of the bottom case 14 of the creation 10, which can be engaged with the centrifugal seat 40, and the prior art is The centrifugal crucible is fixed by means of vacuum holding to the centrifugal seat. This design allows the creation. The 10 is more stably placed on the centrifugal seat 40.

Please refer to the sixth figure. The sixth figure is a schematic diagram of the fifth embodiment of the present invention. The figure shows that the creation 10 can be combined with a centrifuge 30. The centrifuge 30 includes a centrifugal seat 40, a clamp 20 and optical sensing. The instrument 60, the centrifugal seat 40 can be coupled to the present invention 10 through the protrusion 142 on the periphery of the bottom case 14, and the clamp 20 can clamp the fixing member 35 to fix the static head 3, and the outer casing 1 can be transparent. The material can be combined with an optical sensing instrument 60, and the optical sensing instrument 60 can detect changes within the creation 10.

Referring to the seventh embodiment, a partial cross-sectional view of the sixth embodiment of the present invention, the bottom surface of the collecting portion 21 of the present invention 10 is inclined downward from the periphery toward the stator head 3, and the connecting portion of the blood vessel 32 and the collecting portion 21 is disposed at At the lowest point of the collecting portion 21, this embodiment will no longer have the upper skirt 321 and the lower skirt 322. During centrifugation, the centrifuged material is temporarily stored in the collecting portion 21, and the blood vessel 32 is not temporarily discharged. When the centrifuge 30 stops supplying blood, the centrifuged material is extracted by the blood vessel 32. The advantage of this embodiment is that the centrifugal substance can be collected in batches and is not easily contaminated by other substances, and the concentration of the centrifugal substance obtained is surprisingly high. it is good.

It can be seen from the above description that the blood centrifuge 10 provided by the present invention has industrial use value, but the above description is only a description of the preferred embodiment of the present invention, and those skilled in the art can according to the above description. And for all other improvements, these changes are still within the spirit of this creation and the scope of patents defined below.

10‧‧‧ blood centrifugation

1‧‧‧Shell

2‧‧‧core

100‧‧‧ Centrifugal Department

3‧‧‧ 静子头

31‧‧‧Into the blood vessels

32‧‧‧Vascular

12‧‧‧Upper shell

13‧‧‧ Lower shell

14‧‧‧ bottom case

15‧‧‧Shell bevel

23‧‧‧The Ministry of Nuclear Affairs

24‧‧‧Nuclear Department

25‧‧‧The Ministry of Nuclear Affairs

26‧‧‧First core bevel

27‧‧‧Second core bevel

1000‧‧‧Main Centrifugal Department

34‧‧‧Shell cover

35‧‧‧Fixed parts

141‧‧‧ Groove

Claims (10)

A blood centrifuge device comprising: a casing having an opening at the top of the casing; a core disposed inside the casing, the core having a collecting portion at the center of the top surface, the center of the collecting portion Forming a central sleeve penetrating to the bottom of the core, and forming a centrifugal portion between the core and the outer casing, the centrifugal portion connecting the collecting portion; and a stator head, the stator head is disposed in the opening, and the stator The head has an inlet vessel, an outflow vessel, and a seal set, the inlet vessel being coupled to the central cannula, the outlet vessel being coupled to the collection portion, the gasket set securing the stator head to the opening. The blood centrifuge according to claim 1, wherein the outer casing has an upper casing portion, a lower casing portion and a bottom casing, and the upper casing portion and the lower casing portion extend outward to form a casing bevel. The opening is opened at the top of the upper casing portion, and the lower casing portion is connected to the bottom casing. The blood centrifuge according to claim 2, wherein the core is stepped, and the core has an upper core portion, a middle core portion and a lower core portion, and the upper core portion is connected to the middle core portion. Extending outwardly to form a first core bevel, the junction of the middle core portion and the lower core portion extends outward to form a second core inclined surface, the collecting portion is located at a top surface of the upper core portion, and the centrifugal portion is The second core bevel, the middle core portion, the lower core portion, the outer casing bevel and the lower casing portion form a main centrifugal portion. The blood centrifuge according to claim 1, wherein the blood vessel is disposed outside the blood vessel, and the blood vessel is connected to the collecting portion to extend outward to form an upper skirt and a skirt. The upper skirt and the lower skirt are received within the collection portion and the opening. The blood centrifuge according to claim 1, wherein the seal set further comprises a An elastic gasket, a fixed gasket and a ceramic sealing ring are disposed at a proper position of the stator head, and the casing covers the gasket group. The blood centrifuge according to claim 2, wherein a center of the bottom case projects downward with respect to the central sleeve to form a groove. The blood centrifuge according to claim 1, wherein the bottom surface of the core is further provided with a plurality of flow guiding grooves. The blood centrifuge according to claim 1, wherein the core is provided with at least one drainage groove, and one end of the drainage groove is connected to the centrifugal portion, and the drainage groove is connected to the collection portion. The blood centrifuge according to claim 2, wherein at least one bump is disposed on a periphery of the bottom case. The blood centrifuge according to claim 1, wherein the bottom surface of the collecting portion is inclined downward from the periphery toward the stator head, and the outlet of the blood vessel and the collecting portion is disposed at a lowest point of the collecting portion.