M289330 • 八、新型說明： 【新型所屬之技術領域】 ^ 本創作係提供一種高抗壓性含抗生素骨水泥人工關 '節，尤指其技術上提供一種尺寸準確、内含金屬支撐架、 且一體成型製作之高抗壓性含抗生素骨水泥人工關節作為 第一階段髖關節深部感染重建手術使用。 【先前技術】 人工髖關節置換手術後，因髖關節深部感染而導致必 Φ 須施行重建手術，始終是骨科醫師的極大挑戰。臨床處理 上，去除所有的人工關節感染元件及細胞組織是根絕感染 來源的最有效方法。傳統上，治療髖關節深部感染的方法， 主要是以二階段重建手術重新置換人工髖關節。處理程 序，乃是將已遭感染的人工關節元件及細胞組織去除後， 將數量眾多、含有抗生素的顆粒狀骨水泥暫時填充於骨髓 腔内被感染而遭去除之元件及細胞組織所殘留的空間，俟 Φ 病毒完全消滅後，取出此暫時性填充之顆粒狀骨水泥，重 新置入永久性之人工髖關節。第一階段過程中，含抗生素 的顆粒狀骨水泥雖可於局部區域有效釋放高濃度的抗生 素，但由於顆粒狀骨水泥本身無法承受任何微弱的壓力負 荷，導致髖關節於此階段喪失活動機能；致使軟組織扭曲 變形及骨質嚴重疏鬆，最後將導致二階段永久性人工髖關 節的重建手術更為困難。 為解決此一臨床上所遭遇的棘手問題，創作人先前作 法曾針對髖關節深部感染之病患，利用一體成型之暫時性 M289330 填充骨水泥，施以二階段人工tt關節的重建手術，經術後 臨床追縱，證實效果良好◦治療的方法，乃是捨棄傳統上 以數量眾多之顆粒狀骨水泥填充於骨髓腔之過程，改以利 '用單一且幾何形狀接近骨髓腔殘留空間之含抗生素骨水泥 暫時填充於骨髓腔内，俟病毒完全消滅後，取出此幾何形 狀符合骨髓腔殘留空間之暫時性填充骨水泥後，再施以第 二階段之重建手術，重新置入永久性人工髖關節。 由於第一階段所採用之含抗生素骨水泥為其製作方 . 法為一體成型，其抗壓性遠優於顆粒狀骨水泥，有效解決 傳統治療所發生之軟組織扭曲變形及骨質嚴重疏鬆等後遺 症。上述新式之二階段重建手術方法，其臨床效果雖然優 異，唯骨水泥係以橡膠模具一體成型製造，模具本身無法 高溫消毒且製得之骨水泥成品抗壓性仍有一定限制。 是以，針對上述習知結構所存在之問題點，如何開發 一種更具理想實用性之創新結構，實消費者所殷切企盼， Φ 亦係相關業者須努力研發突破之目標及方向。 有鑑於此，創作人本於多年從事相關產品之製造開發 與設計經驗，針對上述之目標，詳加設計與審慎評估後， 終得一確具實用性之本創作。 【新型内容】 欲解決之技術問題點：由於顆粒狀骨水泥本身無法承 受任何微弱的壓力負荷，導致髖關節於此階段喪失活動機 能；致使軟組織扭曲變形及骨質嚴重疏鬆，最後將導致二 階段永久性人工髖關節的重建手術更為困難。 M289330 創作人先前採用一體成型含抗生素骨水泥t其抗 遠優於顆粒狀骨水泥，有效解決傳統治療所發生之軟 扭曲變形及骨質嚴重疏鬆等後遺症，惟，骨水泥係以 '模具一體成型製造，模具本身無法高溫消毒且製得之 泥成品抗壓性仍有一定限制。 解決問題之技術特點：提供一尺寸準確、内含金 撐架、且一體成型製作之高抗壓性含抗生素骨水泥人 節，針對髖關節深部感染施以二階段重建手術。 •本項高抗壓性含抗生素骨水泥人工關節具備以下特色 一、以一體成型骨水泥取代顆粒狀骨水泥填充於骨髓 目前全球仍無類似之髖關節深部感染治療觀念，臨床 機制深具獨創性。第二、依骨髓腔幾何形狀一體成型 之含抗生素骨泥人工關節，内部另包埋高強度金屬支 可大幅提高抗壓性，大幅提高治療髖關節深部感染手 功率。第三、治療髖關節深部感染之方法，制式化骨 Φ 人工關節成型技術之開發，極具價值◦第四、一體成 壓製作。過程中，完全參照病患之體型設計，其抗壓 優於顆粒狀骨水泥，有效解決傳統治療所發生之軟組 曲變形及骨質嚴重疏鬆等後遺症。 對照先前技術之功效：以一體成型骨水泥取代習 粒狀骨水泥填充於骨髓腔，目前全球仍無類似之髖關 部感染治療觀念，臨床治療機制深具獨創性，依骨髓 何形狀一體成型製成之含抗生素骨泥人工關節，内部 埋高強度金屬支架，可大幅提高抗壓性，大幅提高治 壓性 組織 橡膠 骨水 屬支 工關 :第 腔， 治療 製成 架， 術成 水泥 型模 性遠 織扭 式顆 節深 腔幾 另包 療髖 7 M289330 關節深部感染手術成功率，習式無法承受任何微弱壓 荷，治療髖關節深部感染之方法，制式化骨水泥人工 成型技術之開發，極具價值，本創作採一體成型模壓 習式則無。 有關本創作所採用之技術、手段及其功效，茲舉 佳實施例並配合圖式詳細說明於后，相信本創作上述 的、構造及特徵，當可由之得一深入而具體的瞭解。 【實施方式】 本創作係提供一種高抗壓性含抗生素骨水泥人 節設計者。 為使 貴審查委員對本創作之目的、特徵及功效 有更進一步之瞭解與認識，茲請配合圖式簡單說明詳 後： 因髖關節深部感染而施行重建手術的首要目的 底消滅致病細菌並有效恢復體關節之原有功能。為達 目的，去除所有的感染元件及細胞組織後，以一階段 階段方式重新植入新人工關節是常被使用的治療手段 據臨床文獻報告，以二階段重建手術方式治療髖關節 感染，其術後成功率可達82%至96%，遠高於以一階段 療方式。以下三個條件是導致二階段重建手術高成功 主要要素： 一、外來感染元件的徹底清除： 在二階段重建手術中的第一階段處理過程中，須完全 底的取出所有的外來感染元件，尤其又以遭感染骨水 力負 關節 製作 一較 之目 工關 能夠 述如 是徹 此一 或二 。依 深部 的治 率的 且徹 泥的 M289330 去除最為關鍵。M c D ο n a 1 d e t a 1 .於1 9 8 9年的臨床報告指 出，第一階段處理過程中，未完全清除遭感染骨水泥的7 名病患中，有 3名病患於二階段重建手術後再次感染 ’ （45%);反之，7 5名完全清除遭感染骨水泥的病患中，卻 僅有8名於術後再次感染（1 1 % )。 二、 含抗生素骨水泥的使用： 於第一階段處理過程中去除遭感染的人工關節元件及細胞 組織後，使用含抗生素的骨水泥暫時填充於骨髓腔内，將 ® 可於局部感染區域有效釋放高濃度的抗生素，有效達到消 滅病毒的目的。1 9 8 1年B u c h ο 1 z e t a 1.首次提出利用骨水 泥做為傳送抗生素載子的臨床報告，手術成功率為 7 7%。 其後又有學者利用顆粒狀、含抗生素的骨水泥做為暫時填 充物，於第二階段植入永久性人工髖關節前，暫時填充於 骨ft腔内，達到消滅病毒的目的。 三、 ESR及CRP的的使用： φ 利用ESR及CRP來監測治療功效並估算第二階段植入永久 性人工髖關節的時機，是二階段重建手術成功與否的重要 因素。以往諸多文獻建議二階段重建手術中，第一階段與 第二階段的時間間隔應視病源毒性、感染嚴重度及病患對 於治療的反應……等諸多因素而有所差異，以一個月至一 年最為適當。 綜上所述，含抗生素骨水泥的使用在第一階段的治療中， 極為重要◦此階段若未利用骨水泥做為暫時性填充物，下 肢將因去除被感染之元件及細胞組織所殘留的空間而喪失 M289330 " 重要功能，在第二階段重建手術施行之前的時段内，病患 將承受無法忍受之痛苦。因此臨床處理上，治療髖關節深 '部感染的方法，主要是以二階段重建手術重新置換人工髖 '關節。在第一階段的處理方法，乃是將已遭感染的人工關 節元件及細胞組織去除後，將數量眾多、含有抗生素的顆 粒狀骨水泥暫時填充於骨髓腔内被感染而遭去除之元件及 細胞組織所殘留的空間，俟病毒完全消滅後，取出此暫時 性填充之顆粒狀骨水泥後，再施以第二階段的治療---重新 ® 置入永久性之人工髖關節。第一階段過程中，含抗生素的 顆粒狀骨水泥雖可於局部區域有效釋放高濃度的抗生素， 但是由於顆粒狀骨水泥本身無法承受任何微弱的壓力負 荷，導致髖關節於此階段喪失活動機能；致使軟組織扭曲 變形及骨質嚴重疏鬆，最後將導致二階段永久性人工髖關 節的重建手術更為困難。 為解決上述臨床所遭遇的棘手問題，創作人曾針對髖關節 _ 深部感染之病患，利用一體成型之暫時性填充骨水泥，施 以二階段人工髖關節的重建手術，經術後臨床追蹤，證實 效果良好。治療的方法，乃是捨棄傳統上以數量眾多之顆 粒狀骨水泥填充於骨髓腔之過程，改以利用單一且幾何形 狀接近骨髓腔殘留空間之含抗生素骨水泥暫時填充於骨髓 腔内，俟病毒完全消滅後，取出此幾何形狀符合骨髓腔殘 留空間之暫時性填充骨水泥後，再施以第二階段之重建手 術，重新置入永久性人工髖關節。由於第一階段所採用之 含抗生素骨水泥為其製作方法為一體成型，其抗壓性遠優 10 M289330 於顆粒狀骨水泥，有效解決傳統治療所發生之軟組織扭曲 變形及骨質嚴重疏鬆等後遺症。 ' 針對上述新式之二階段重建手術方法中所需使用的 ^骨水泥一體成型模具，創作人過去曾經進行兩度改良，其 中第一代成型模具為利用現有之金屬人工髖關節直接翻模 製造，所使用之材質為矽橡膠◦由於模具本身無法直接承 受高溫消毒，以醋酸浸泡方式消毒，操作不便。 參閱第一圖所示，係該本創作之骨水泥成型模具平面 不意圖^為改良弟一代模具無法南溫消毒的缺點’另開發 金屬材質之第二代骨水泥成型模具，該模具包含有公模（1 0 )與母模（2 0 )合模而成，公模（1 0 )、母模（2 0 ) 兩半模於合模後，形成一端為半球頭（1 1 )，另端為半球 頭之内腔（1 2 )。合模後之模具外部一端附骨水泥注射口 (1 3 )，另端附透氣口 （ 1 4 )。 參閱第二圖所示，係該本創作之支撐架立體示意圖， 0 由於骨水泥材質屬易砰材料’為加強所製得骨水泥植入物 之機械強度，在利用第二代模具製造骨水泥植入物的過程 中，於模具料腔内預埋金屬材質支撐架（3 0 )，支撐架（3 0 )前端亦形成一半球頭（3 1 )及一彎曲之桿身（3 2 )， 而末端形成漸縮桿身接一反向半球頭形狀之牽引件（3 3 )，藉該牽引件（3 3 )得在取出骨水泥人工關節而有折 斷情形時，以牽引件（3 3 )得順利將斷的部份一併拉出。 參閱第三圖所示，係為本創作之骨水泥人工關節平面 示意圖，上述製作人工關節，俟骨水泥硬化脫模後，即獲 M289330 得一抗壓性較佳之内含金屬材質支撐架（3 Ο )之骨水泥 人工關節（4 0 )，骨水泥人工關節（4 0 )内含抗生素者。 ~ 利用此第二代模具一體成型製得之骨水泥人工關 4節，施以二階段人工髖關節的重建手術，經術後臨床追蹤， 證實效果良好。 參閱第四圖所示，係為髖臼壓桿平面示意圖，其中， 骨寬臼壓桿（5 0 ) —端為半球頭（5 1 )。手術間，當骨水 泥於黏稠狀態塗怖於髖臼端時，此項髖臼壓桿（5 0 )用 ® 於擠壓髖臼外部骨水泥，使髖臼外緣之骨水泥壓成規則半 球。 本創作功效增進之事實如下： 第一、以一體成型骨水泥取代顆粒狀骨水泥填充於骨 髓腔，目前全球仍無類似之髖關節深部感染治療觀念，臨 床治療機制深具獨創性。 第二、依骨髓腔幾何形狀一體成型製成之含抗生素骨 φ 水泥人工關節，内部另包埋高強度金屬支架，可大幅提高 抗壓性，大幅提高治療髖關節深部感染手術成功率。 第三、治療髖關節深部感染之方法，制式化骨水泥人 工關節成型技術之開發，極具價值。 第四、一體成型模壓製作。過程中，完全參照病患之 體型設計，其抗壓性遠優於顆粒狀骨水泥，有效解決傳統 治療所發生之軟組織扭曲變形及骨質嚴重疏鬆等後遺症。 由其上述可知，本創作之高抗壓性含抗生素骨水泥人 工關節，確為業界首見而符合新型專利之新穎性要件者， M289330 ‘ 而其全面性之創新設計。符合新型專利之進步性要件，而 其深具成效，符合較佳之產業利用性者。 ' 前文係針對本創作之較佳實施例為本創作之技術特徵 4 進行具體之說明；惟，熟悉此項技術之人士當可在不脫離 本創作之精神與原則下對本創作進行變更與修改，而該等 變更與修改，皆應涵蓋於如下申請專利範圍所界定之範疇 中 〇 綜上所述，本創作係提供一種高抗壓性含抗生素骨水 — 泥人工關節，其嫁已達到本創作之所有目的，另其組合結 構之空間型態未見於同類產品，亦未曾公開於申請前，已 符合專利法之規定，爰依法提出申請。 【圖式簡單說明】 第一圖：係該本創作之骨水泥成型模具平面示意圖。 第二圖：係該本創作之支撐架立體示意圖。 第三圖：係為本創作之骨水泥人工關節平面示意圖。 Φ 第四圖：係為髖臼壓桿平面示意圖。 【主要元件符號說明】 (1 0 )公模 （1 1 )半球頭 (1 2 )内腔 （1 3 )骨水泥注射口 (14)透氣口 （20)母模 (30)支撐架 （31)半球頭 (3 2 )桿身 （3 3 )牽引件 (4 0 )骨水泥人工關節（5 0 )髖臼壓桿 (5 1 )半球頭 13M289330 • VIII. New Description: 【New Technical Fields】 ^ This creative department provides a high-pressure antibiotic-containing bone cement artificial joint section, especially that it provides a dimensionally accurate, embedded metal support frame, and The one-piece high-pressure-resistant antibiotic-containing cement joint is used as the first stage of deep reconstruction of hip joint infection. [Prior Art] After artificial hip joint replacement surgery, it is always a great challenge for orthopedic surgeons to perform reconstruction surgery due to deep hip infection. In clinical treatment, removal of all artificial joint infection components and cellular tissue is the most effective way to eradicate the source of infection. Traditionally, the method of treating deep hip infections has been to replace the artificial hip joints with a two-stage reconstruction surgery. The treatment procedure is to remove the infected artificial joint elements and cell tissues, and temporarily fill a large amount of antibiotic-containing granular bone cement in the space of the bone marrow cavity to be infected and removed. After the 俟Φ virus is completely eliminated, the temporarily filled granular cement is removed and the permanent artificial hip joint is reinserted. In the first stage, the antibiotic-containing granular cement can effectively release high concentrations of antibiotics in local areas, but the granular bone cement itself cannot withstand any weak pressure load, resulting in the loss of activity of the hip joint at this stage; The resulting soft tissue distortion and severe osteoporosis will eventually lead to more difficult reconstruction of the second-stage permanent artificial hip joint. In order to solve the thorny problem encountered in this clinical practice, the creator's previous practice was to treat the patients with deep hip infection, using the one-piece temporary M289330 to fill the bone cement, and apply the reconstruction of the two-stage artificial tt joint. After clinical follow-up, the method of confirming the effect of good treatment is to abandon the traditional process of filling the marrow cavity with a large number of granular cement, and to improve the use of antibiotics with a single and geometric shape close to the residual space of the bone marrow cavity. The bone cement is temporarily filled in the bone marrow cavity, and after the prion is completely eliminated, the temporary filling of the bone cement with the geometric shape conforming to the residual space of the bone marrow cavity is taken, and then the second stage reconstruction operation is performed, and the permanent artificial hip joint is repositioned. . Because the antibiotic-containing bone cement used in the first stage is made by one method, the pressure resistance is much better than that of granular bone cement, which effectively solves the sequelae of soft tissue distortion and severe osteoporosis which occur in traditional treatment. Although the clinical effect of the above-mentioned new two-stage reconstruction surgery method is superior, the bone cement is integrally molded by a rubber mold, and the mold itself cannot be autoclaved and the pressure resistance of the obtained bone cement product is still limited. Therefore, in view of the problems existing in the above-mentioned conventional structure, how to develop an innovative structure with more ideal and practicality, the consumers are eagerly awaiting, Φ is also the relevant industry to strive to develop breakthrough goals and directions. In view of this, the creator has been engaged in the manufacturing development and design experience of related products for many years. After detailed design and careful evaluation of the above objectives, the creator will have a practical and practical creation. [New content] The technical problem to be solved: Since the granular bone cement itself cannot withstand any weak pressure load, the hip joint loses its active function at this stage; causing the soft tissue to be distorted and the bones to be severely loose, which will eventually lead to the second stage permanent Reconstructive surgery for sexual hip joints is more difficult. M289330 creators have previously adopted one-piece antibiotic-containing bone cement, which is far superior to granular cement, which effectively solves the sequelae of soft distortion and severe osteoporosis in traditional treatment. However, bone cement is manufactured by 'mould integrally molding'. The mold itself cannot be autoclaved and the pressure resistance of the prepared mud product is still limited. The technical feature of solving the problem: providing a high-pressure antibiotic-containing cemented cement with an accurate size, containing gold brackets and integrally formed, and performing a two-stage reconstruction operation for deep hip infection. • This high-pressure-resistant antibiotic-containing bone cement artificial joint has the following characteristics: 1. The bone cement is replaced by granular cement in one body. The bone marrow cement is filled in the bone marrow. There is still no similar concept of deep hip infection in the world, and the clinical mechanism is original. . Secondly, the artificial joint containing antibiotic bone mud integrated with the geometry of the bone marrow cavity, and the high-strength metal branch embedded inside can greatly improve the compression resistance and greatly improve the hand power for treating deep hip infection. Third, the method of treating deep infection of the hip joint, the standardized bone Φ The development of the artificial joint forming technology is extremely valuable, and the fourth is integrated into the pressure production. In the process, the patient's body design is completely referenced, and its compression resistance is superior to that of granular bone cement, which effectively solves the sequelae of soft tissue deformation and severe osteoporosis which occur in traditional treatment. Compared with the efficacy of the prior art: the integrated bone cement replaces the granular cement in the bone marrow cavity. At present, there is no similar concept of treatment of the hip infection in the world. The clinical treatment mechanism is original and unique. The artificial joint containing antibiotic bone mud and internal high-strength metal stent can greatly improve the compression resistance, and greatly improve the pressure-bearing tissue rubber bone water to support the work: the first cavity, the treatment frame, the cement mold Sexual far-twisted knuckle deep cavity several other treatment hips 7 M289330 Joint deep infection surgery success rate, the formula can not withstand any weak pressure, the method of treating deep hip infection, the development of standard bone cement artificial molding technology, Very valuable, this creation adopts one molding molding practice. With regard to the techniques, means and functions of the present invention, it is believed that the above-mentioned embodiments, constructions and features of the present invention can be obtained from a detailed and detailed understanding. [Embodiment] This creation provides a high-pressure antibiotic-containing cemented cement designer. In order to enable your review committee to have a better understanding and understanding of the purpose, characteristics and efficacy of this creation, please briefly explain the details of the following: The primary purpose of performing reconstruction surgery due to deep hip infection is to eliminate pathogenic bacteria and effectively Restore the original function of the body joints. For the purpose of removing all infected components and cell tissue, re-implanting new artificial joints in a one-stage phase is a commonly used treatment. According to clinical literature reports, two-stage reconstruction surgery is used to treat hip infections. The success rate can reach 82% to 96%, which is much higher than the one-stage treatment. The following three conditions are the main factors leading to the high success of the two-stage reconstruction surgery: 1. Thorough removal of foreign infection components: During the first phase of the two-stage reconstruction surgery, all foreign infection components must be completely removed, especially It is also possible to describe the negative joints of infected bones and waters as one or two. The removal of the M289330, which is based on the deep treatment rate and the mud, is the most critical. M c D ο na 1 deta 1. In the clinical report of 1989, during the first phase of treatment, 3 of the 7 patients who did not completely remove the infected bone cement were rebuilt in two stages. Re-infection after surgery (45%); conversely, only 7 of the 75 patients who completely cleared the infected bone cement were re-infected after surgery (11%). Second, the use of antibiotic-containing bone cement: After removing the infected artificial joint components and cell tissue during the first stage of treatment, the bone cement containing antibiotics is temporarily filled in the marrow cavity, and the ® can be effectively released in the local infected area. High concentrations of antibiotics effectively achieve the purpose of eliminating the virus. 1 9 8 1 B u c h ο 1 z e t a 1. The clinical report of using bone cement as a carrier for antibiotics was first proposed. The success rate was 7 7%. Later, some scholars used granular, antibiotic-containing bone cement as a temporary filling. Before the permanent artificial hip joint was implanted in the second stage, it was temporarily filled in the bone ft cavity to eliminate the virus. III. Use of ESR and CRP: φ The use of ESR and CRP to monitor treatment efficacy and estimate the timing of second-stage permanent hip joint implantation is an important factor in the success of a two-stage reconstruction procedure. In the past, many literatures suggest that in the second-stage reconstruction surgery, the interval between the first phase and the second phase should be different depending on factors such as the toxicity of the source, the severity of the infection, and the response of the patient to the treatment, etc., from one month to one. The year is most appropriate. In summary, the use of antibiotic-containing bone cement is extremely important in the first stage of treatment. If bone cement is not used as a temporary filling at this stage, the lower limbs will be removed by removing the infected components and cellular tissues. Space and loss of M289330 " important function, the patient will suffer unbearable pain during the period before the second stage reconstruction surgery. Therefore, in clinical treatment, the method for treating deep 'frontal infections of the hip joints is mainly to replace the artificial hip joints by two-stage reconstruction surgery. In the first stage of treatment, after the infected artificial joint elements and cell tissues are removed, a large number of granular bone cement containing antibiotics are temporarily filled in the bone marrow cavity and infected and removed. After the prion is completely destroyed, the space left in the tissue is removed, and then the temporary filling of the granular cement is taken out, and then the second stage of treatment is applied - re-positioning the permanent artificial hip joint. During the first stage, the antibiotic-containing granular cement can effectively release high concentrations of antibiotics in local areas, but the granular bone cement itself cannot withstand any weak pressure load, resulting in loss of activity of the hip joint at this stage; The resulting soft tissue distortion and severe osteoporosis will eventually lead to more difficult reconstruction of the second-stage permanent artificial hip joint. In order to solve the thorny problems encountered in the above clinical practice, the creator used a one-time temporary filling of bone cement and a reconstruction of the two-stage artificial hip joint for patients with hip-deep infection. It proved to be effective. The treatment method is to abandon the process of filling the bone marrow cavity with a large number of granular cements, and temporarily fill the bone marrow cavity with the antibiotic bone cement with a single and geometric shape close to the residual space of the bone marrow cavity, prion After complete elimination, the temporary filling of the bone cement with the geometry of the residual space of the medullary cavity was taken out, and then the second stage reconstruction operation was performed to re-insert the permanent artificial hip joint. Because the antibiotic-containing bone cement used in the first stage is integrally formed by its production method, its pressure resistance is superior to 10 M289330 in granular bone cement, which effectively solves the sequelae of soft tissue distortion and severe osteoporosis which occur in traditional treatment. The creators have made two improvements in the past for the new bone cement integrated molding tool used in the new two-stage reconstruction surgery method. The first generation molding dies were made by using the existing metal artificial hip joint directly. The material used is 矽 rubber ◦ because the mold itself cannot directly withstand high temperature sterilization, and is sterilized by acetic acid soaking, which is inconvenient to operate. Referring to the first figure, the bone cement molding die plane of this creation is not intended to improve the shortcomings of the younger generation mold that cannot be disinfected by the south temperature. The second generation of bone cement molding die of the metal material is further developed. The mold (10) is combined with the master mold (20). The male mold (10) and the female mold (20) are half-mesh heads (1 1 ) and the other ends are formed. It is the inner cavity of the hemisphere (1 2 ). After the mold is closed, the outer end of the mold is attached with a cement injection port (1 3 ), and the other end is provided with a vent (1 4 ). Referring to the second figure, it is a three-dimensional schematic diagram of the support frame of the present invention. 0 Since the bone cement material is an easy-to-smoke material to strengthen the mechanical strength of the bone cement implant, the second generation mold is used to manufacture the bone cement. During the process of implanting, a metal support frame (30) is embedded in the cavity of the mold, and a front end of the support frame (30) also forms a half ball head (3 1 ) and a curved shaft body (3 2 ). The end portion forms a traction member (3 3 ) which is in the shape of a reverse hemisphere head, and the traction member (3 3 ) is used to take the bone cement joint joint and break, and the traction member (3 3 ) It is necessary to pull out the broken parts together. Referring to the third figure, it is a schematic plan view of the artificial cement joint of the creation. After the artificial joint is prepared, the humeral cement is hardened and demoulded, and then the M289330 obtains a metal-resistant support frame with better compression resistance. Ο) The cement joint of the cement (40), the cement joint (40) contains antibiotics. ~ The bone cement used in this second-generation mold integrated molding was manually closed for 4 sections, and the reconstruction of the second-stage artificial hip joint was performed. After clinical follow-up, the effect was confirmed to be good. Referring to the fourth figure, it is a plan view of the acetabular compression rod, wherein the bone width compression rod (50) is the hemispherical head (5 1 ). In the operation room, when the bone cement is applied to the acetabular end in a viscous state, the acetabular compression rod (50) is used to squeeze the outer bone cement of the acetabulum to press the bone cement of the outer edge of the acetabulum into a regular hemisphere. . The facts of this creative effect enhancement are as follows: First, the replacement of granular cement by integral bone cement is filled in the bone marrow cavity. At present, there is no similar concept of deep hip infection treatment in the world, and the clinical treatment mechanism is profound. Secondly, the antibiotic bone φ cement artificial joint formed by the bone marrow cavity geometry is integrally embedded with a high-strength metal stent, which can greatly improve the compression resistance and greatly improve the success rate of the deep hip infection treatment. Third, the method of treating deep infection of the hip joint, the development of the artificial bone cement artificial joint forming technology, is of great value. Fourth, integrated molding and molding. In the process, the patient's body design is completely referenced, and its compression resistance is much better than that of granular bone cement, which effectively solves the sequelae of soft tissue distortion and severe osteoporosis which occur in traditional treatment. It can be seen from the above that the high-pressure-resistant antibiotic-containing cement joints of this creation are indeed the first in the industry and meet the novelty requirements of the new patent, M289330 ‘and its comprehensive innovative design. It meets the progressive requirements of the new patent, and it is highly effective and meets the needs of better industrial use. The foregoing is a description of the technical features of the present invention for the preferred embodiment of the present invention; however, those skilled in the art can make changes and modifications to the present invention without departing from the spirit and principles of the present invention. These changes and modifications shall be covered in the scope defined by the following patent application scope. The creation provides a high-pressure antibiotic-containing bone-mud artificial joint, which has reached the present creation. For all purposes, the spatial pattern of the combined structure is not found in similar products, nor has it been disclosed before the application, has complied with the provisions of the Patent Law, and has applied for it according to law. [Simple description of the diagram] The first picture: is a schematic plan view of the bone cement molding mold of the present creation. The second picture is a three-dimensional diagram of the support frame of the present creation. The third picture: the schematic diagram of the artificial cement joint of the creation. Φ The fourth picture is a plan view of the acetabular pressure bar. [Main component symbol description] (1 0) Male mold (1 1) Hemispherical head (1 2 ) Inner cavity (1 3) Bone cement injection port (14) Ventilation port (20) Female mold (30) Support frame (31) Hemispherical head (3 2 ) shaft (3 3 ) traction member (40) bone cement artificial joint (50) acetabular compression rod (5 1) hemisphere head 13