TWI865470B - 治療眼睛疾病之肽及醫藥組合物 - Google Patents

治療眼睛疾病之肽及醫藥組合物 Download PDF

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Publication number
TWI865470B
TWI865470B TW108141290A TW108141290A TWI865470B TW I865470 B TWI865470 B TW I865470B TW 108141290 A TW108141290 A TW 108141290A TW 108141290 A TW108141290 A TW 108141290A TW I865470 B TWI865470 B TW I865470B
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TW
Taiwan
Prior art keywords
yde
compound
substituted
pharmaceutically acceptable
certain embodiments
Prior art date
Application number
TW108141290A
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English (en)
Chinese (zh)
Other versions
TW202031675A (zh
Inventor
白泰坤
崔種允
閔景昱
朴駿鎬
Original Assignee
南韓商柳柳製藥股份有限公司
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Publication of TW202031675A publication Critical patent/TW202031675A/zh
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04—Linear peptides containing only normal peptide links
    • C07K7/06—Linear peptides containing only normal peptide links having 5 to 11 amino acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0048—Eye, e.g. artificial tears
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/08—Solutions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Ophthalmology & Optometry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Epidemiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Immunology (AREA)
TW108141290A 2018-11-14 2019-11-13 治療眼睛疾病之肽及醫藥組合物 TWI865470B (zh)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201862767180P 2018-11-14 2018-11-14
US62/767,180 2018-11-14

Publications (2)

Publication Number Publication Date
TW202031675A TW202031675A (zh) 2020-09-01
TWI865470B true TWI865470B (zh) 2024-12-11

Family

ID=70732068

Family Applications (1)

Application Number Title Priority Date Filing Date
TW108141290A TWI865470B (zh) 2018-11-14 2019-11-13 治療眼睛疾病之肽及醫藥組合物

Country Status (10)

Country Link
EP (1) EP3880690A4 (enExample)
JP (1) JP7522732B2 (enExample)
KR (1) KR20210087539A (enExample)
CN (1) CN113474356B (enExample)
AU (1) AU2019378162B2 (enExample)
BR (1) BR112021009341A2 (enExample)
MX (1) MX2021005077A (enExample)
SG (1) SG11202104178TA (enExample)
TW (1) TWI865470B (enExample)
WO (1) WO2020099925A2 (enExample)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US12037415B2 (en) 2017-05-17 2024-07-16 Yuyu Pharma, Inc. Peptide and pharmaceutical composition for treating an eye disease comprising the same as an active pharmaceutical ingredient
US11613558B2 (en) 2018-11-14 2023-03-28 Yuyu Pharma, Inc. Peptides and pharmaceutical compositions for treating eye diseases
BR112021023477A2 (pt) 2019-05-21 2022-02-15 Eyebio Korea Novo composto peptídico, composição farmacêutica para prevenir ou tratar inflamação, composição de alimento para prevenir ou amenizar a inflamação e composição de cosmético tendo um efeito anti inflamatório
WO2021191689A2 (en) * 2020-03-05 2021-09-30 Yuyu Pharma, Inc. Treatment of inflammatory diseases with peptides and pharmaceutical compositions
MX2024006997A (es) * 2021-12-13 2024-06-19 Eyebiokorea Inc Composicion para el tratamiento de la degeneracion macular que comprende un nuevo peptido.
KR102662922B1 (ko) * 2022-05-31 2024-05-03 주식회사 세네릭스 신규의 d-아미노산 유도체 및 이를 포함하는 약학 조성물

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6037135A (en) * 1992-08-07 2000-03-14 Epimmune Inc. Methods for making HLA binding peptides and their uses
KR101690539B1 (ko) * 2015-07-30 2016-12-29 주식회사 아이바이오코리아 건성안 예방 또는 치료용 약학조성물
ES2822289T3 (es) * 2016-04-08 2021-04-30 Eyebio Korea Péptido a base de colágeno tipo II alfa-1 para su uso en el tratamiento de la degeneración macular
KR101795653B1 (ko) * 2016-05-19 2017-11-09 인제대학교 산학협력단 콜라겐 타입 ii 펩타이드-아플리버셉트의 키메라 단백질을 유효성분으로 함유하는 혈관신생 억제용 조성물
KR20180074928A (ko) * 2016-12-26 2018-07-04 주식회사 아이바이오코리아 건성안 예방 또는 치료용 동물 의약품 조성물
US12037415B2 (en) * 2017-05-17 2024-07-16 Yuyu Pharma, Inc. Peptide and pharmaceutical composition for treating an eye disease comprising the same as an active pharmaceutical ingredient

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
期刊 Lee et al., "Anti-inflammatory effect of hydroxyproline-GQDGLAGPK in desiccation stress-induced experimental dry eye mouse", Scientific Reports, 2017, 7, no.7413.

Also Published As

Publication number Publication date
MX2021005077A (es) 2021-08-11
CN113474356A (zh) 2021-10-01
WO2020099925A3 (en) 2020-06-25
KR20210087539A (ko) 2021-07-12
EP3880690A2 (en) 2021-09-22
JP2022507404A (ja) 2022-01-18
SG11202104178TA (en) 2021-05-28
JP7522732B2 (ja) 2024-07-25
TW202031675A (zh) 2020-09-01
BR112021009341A2 (pt) 2021-08-10
EP3880690A4 (en) 2023-09-13
CN113474356B (zh) 2024-12-17
WO2020099925A2 (en) 2020-05-22
CA3119921A1 (en) 2020-05-22
AU2019378162B2 (en) 2025-01-30
AU2019378162A1 (en) 2021-05-20

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