TWI859508B - 骨骼疾病治療用醫藥組成物 - Google Patents

骨骼疾病治療用醫藥組成物 Download PDF

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Publication number
TWI859508B
TWI859508B TW111105929A TW111105929A TWI859508B TW I859508 B TWI859508 B TW I859508B TW 111105929 A TW111105929 A TW 111105929A TW 111105929 A TW111105929 A TW 111105929A TW I859508 B TWI859508 B TW I859508B
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TW
Taiwan
Prior art keywords
cells
mesenchymal stem
stem cells
cell
pharmaceutical composition
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TW111105929A
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English (en)
Chinese (zh)
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TW202302123A (zh
Inventor
竹谷健
小田泰昭
伊谷有未
陶山𨺓史
Original Assignee
日商PuREC股份有限公司
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Publication of TW202302123A publication Critical patent/TW202302123A/zh
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/28Bone marrow; Haematopoietic stem cells; Mesenchymal stem cells of any origin, e.g. adipose-derived stem cells
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/48Reproductive organs
    • A61K35/51Umbilical cord; Umbilical cord blood; Umbilical stem cells
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • A61P19/08Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06Animal cells or tissues; Human cells or tissues

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Developmental Biology & Embryology (AREA)
  • Cell Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Virology (AREA)
  • Biotechnology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Epidemiology (AREA)
  • Hematology (AREA)
  • Zoology (AREA)
  • Biomedical Technology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Rheumatology (AREA)
  • Reproductive Health (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
TW111105929A 2021-02-19 2022-02-18 骨骼疾病治療用醫藥組成物 TWI859508B (zh)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2021024794 2021-02-19
JP2021-024794 2021-02-19

Publications (2)

Publication Number Publication Date
TW202302123A TW202302123A (zh) 2023-01-16
TWI859508B true TWI859508B (zh) 2024-10-21

Family

ID=82930724

Family Applications (1)

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TW111105929A TWI859508B (zh) 2021-02-19 2022-02-18 骨骼疾病治療用醫藥組成物

Country Status (7)

Country Link
US (1) US20240316109A1 (https=)
JP (1) JP7636032B2 (https=)
KR (1) KR20230133892A (https=)
AU (1) AU2022222868B2 (https=)
CA (1) CA3211195A1 (https=)
TW (1) TWI859508B (https=)
WO (1) WO2022177032A1 (https=)

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2015043768A (ja) * 2013-08-02 2015-03-12 有未 伊谷 ヒト間葉系幹細胞を特異的に認識するモノクローナル抗体並びにこれを用いたヒト間葉系幹細胞の分離及び/または品質評価を行う方法

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS6363950U (https=) 1986-06-17 1988-04-27
WO2016017795A1 (ja) 2014-08-01 2016-02-04 有未 伊谷 ヒト間葉系幹細胞の品質評価方法、及び、そのためのモノクローナル抗体
WO2021144995A1 (ja) * 2020-01-16 2021-07-22 PuREC株式会社 高純度間葉系幹細胞

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2015043768A (ja) * 2013-08-02 2015-03-12 有未 伊谷 ヒト間葉系幹細胞を特異的に認識するモノクローナル抗体並びにこれを用いたヒト間葉系幹細胞の分離及び/または品質評価を行う方法

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
期刊 Mabuchi et al. LNGFR+THY-1+VCAM-1hi+ Cells Reveal Functionally Distinct Subpopulations in Mesenchymal Stem Cells Stem Cell Reports 1(2) 2013 152-165
期刊 Taketani et al. Ex Vivo Expanded Allogeneic Mesenchymal Stem Cells With Bone Marrow Transplantation Improved Osteogenesis in Infants With Severe Hypophosphatasia Cell Transplantation 24 2015 1931-1943;期刊 Mabuchi et al. LNGFR+THY-1+VCAM-1hi+ Cells Reveal Functionally Distinct Subpopulations in Mesenchymal Stem Cells Stem Cell Reports 1(2) 2013 152-165 *

Also Published As

Publication number Publication date
KR20230133892A (ko) 2023-09-19
JP7636032B2 (ja) 2025-02-26
AU2022222868A1 (en) 2023-09-07
CA3211195A1 (en) 2022-08-25
JPWO2022177032A1 (https=) 2022-08-25
US20240316109A1 (en) 2024-09-26
WO2022177032A1 (ja) 2022-08-25
TW202302123A (zh) 2023-01-16
AU2022222868B2 (en) 2026-03-19

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