TWI825256B - Diagnostic tray assembly - Google Patents

Abstract

Disclosed is a diagnostic tray assembly. According to one aspect of the present invention, disclosed is a diagnostic tray assembly which includes a first tray and a second tray provided in parallel to each other, each of the first and second trays having an accommodation part in which a diagnostic membrane is accommodated, and a connection unit provided between the first tray and the second tray, and having one end portion connected to the first tray and the other end portion connected to the second tray.

Description

Disk composition for diagnosis

The present invention relates to a diagnostic tray composition, and more particularly to a diagnostic tray composition capable of containing an allergen-coated membrane.

Cross-references to related applications

This application claims the priority rights of Korean Patent Application No. 10-2019-0000843 filed on January 3, 2019 and Korean Patent Application No. 10-2019-0133081 filed on October 24, 2019. The above application is hereby incorporated by reference in its entirety.

Diagnostic chips for analyzing components within a sample are usually produced by coating a fixed body in the shape of a diaphragm with an antigen or the like. Subsequently, various biological information can be obtained by reacting the antigen coated on the fabricated diagnostic chip with the sample to be analyzed.

In order to react with the sample on the diagnostic wafer, the diagnostic wafer is loaded on a tray and then mounted on an automated device in which the reaction with the sample takes place. The reaction with the sample is completed in the automated equipment, and the disk with the disk wafer loaded thereon is then removed again.

According to the related art, methods have been used in which, in order to mount several disks on an automated device for reaction with a sample, a plurality of disks are loaded on a single on a frame, and then the frame is loaded on the automation equipment.

However, since this method must involve the steps of loading the disks onto the frame one by one, mounting the frame on the automated equipment, removing the frame from the automated equipment after completing the reaction with the sample, and removing the disks from the frame one by one, The existing problem is that diagnosis requires many steps and a lot of time to analyze the components in the sample.

Furthermore, according to the related art, since a space in which a frame that does not directly react with the sample is installed is necessary within the automated equipment, there is also a problem in terms of space utilization within the automated equipment.

Therefore, when compared to the related art, the problem to be solved by the present invention is to reduce the steps and time required in diagnosis for analyzing components within a sample.

Another problem to be solved by the present invention is maximizing the space utilization within the automated equipment where the reaction with the sample takes place, when compared to the related art.

According to one aspect of the present invention, in order to achieve the above-described object, a disk composition for diagnosis is provided. The disk composition for diagnosis includes: a first disk and a second disk, each of which has a receiving part that accommodates a diaphragm for diagnosis, and the first disk and the second disk are arranged parallel to each other; and a connection unit provided between the first disk and the second disk and having a connection to the first disk one end portion and connected to the other end portion of the second disk, wherein each of the first disk and the second disk has an elongated plate having a predetermined width (W), a predetermined thickness (t) and a predetermined length (L) rod shape shape, the second disk is disposed on the side portion of the first disk in the width (W) direction of the first disk, wherein the connection unit is disposed between the first disk and the second disk, and the connection unit is made of ABS.

The ratio of the length (L) to the width (W) in each of the first tray and the second tray may be 10 to 30, and the length (L) in each of the first tray and the second tray The ratio to thickness (t) can be from 20 to 40.

The connection unit may include a notch part having a concave shape, where the connection unit has a smaller thickness than other areas of the connection unit.

The notch part may be defined in the central portion of the connecting unit in the length (L) direction of the connecting unit.

The notch part may be defined at each of the two end portions of the connecting unit in the length (L) direction of the connecting unit.

The notch part may be defined in each of the areas spaced apart from a corresponding point at which the connection unit is connected to the first disk to a center of the connection unit in a length (L) direction of the connection unit and the second set.

The notch component may have a V-shaped cross-section.

The notch component may have a U-shaped cross-section.

The notch means may be defined only in the top or bottom surface of the connection unit.

Notch features may be defined in each of the top and bottom surfaces of the connection unit.

The notch part defined in the bottom surface of the connection unit may be positioned at a position corresponding to the position of the notch part defined in the top surface of the connection unit.

The connection unit may have a flat surface.

The disc composition for diagnosis may be a disc composition for diagnosing allergy.

According to the present invention, the steps and time required in diagnosis for analyzing components within a sample can be reduced when compared to related techniques.

Also, according to the present invention, space utilization within the automated equipment where the reaction with the sample occurs can be maximized when compared to related technologies.

10: Disk composition for diagnosis

100: first set

110: First containing part

120: First protruding part

200:Second set

210: Second receiving part

220: Second protruding part

300:Connection unit

300a: Notched parts

L: length

t:Thickness

W: Width

FIG. 1 is a perspective view illustrating the appearance of a disk composition for diagnosis according to the present invention when viewed from above.

2 is a perspective view illustrating the appearance of the disk composition for diagnosis according to the present invention when viewed from below.

Figure 3 is a plan view illustrating the structure of a disk composition for diagnosis according to the present invention.

4 is a cross-sectional view illustrating the structure of a diagnostic disc composition taken along line A-A of FIG. 3. FIG.

5 is an enlarged view illustrating a first example of a connection unit for a diagnostic disk composition according to the first embodiment of the present invention.

6 is an enlarged view illustrating a second example of a connection unit for a diagnostic disk composition according to the first embodiment of the present invention.

7 is an enlarged view illustrating a third example of a connection unit for a diagnostic disk composition according to the first embodiment of the present invention.

8 is an enlarged view illustrating a fourth example of a connection unit for a diagnostic disk composition according to the first embodiment of the present invention.

9 is an enlarged view illustrating a first example of a connection unit for a diagnostic disk composition according to the second embodiment of the present invention.

10 is an enlarged view illustrating a second example of a connection unit for a diagnostic disk composition according to the second embodiment of the present invention.

11 is an enlarged view illustrating a third example of a connection unit for a diagnostic disk composition according to the second embodiment of the present invention.

12 is an enlarged view illustrating a fourth example of a connection unit for a diagnostic disk composition according to the second embodiment of the present invention.

13 is an enlarged view illustrating a first example of a connection unit for a diagnostic disk composition according to the third embodiment of the present invention.

14 is an enlarged view illustrating a second example of a connection unit for a diagnostic disk composition according to the third embodiment of the present invention.

15 is an enlarged view illustrating a third example of a connection unit for a diagnostic disk composition according to the third embodiment of the present invention.

16 is an enlarged view illustrating a fourth example of a connection unit for a diagnostic disk composition according to the third embodiment of the present invention.

Hereinafter, the structure of the disk composition for diagnosis according to the present invention will be described with reference to the drawings.

Disk composition for diagnosis

Figure 1 is an illustration of a diagnostic tray according to the present invention when viewed from above. 2 is a perspective view illustrating the appearance of the disk composition for diagnosis according to the present invention when viewed from below. 3 is a plan view illustrating the structure of the disk composition for diagnosis according to the present invention, and FIG. 4 is a cross-sectional view illustrating the structure of the disk composition for diagnosis taken along line A-A of FIG. 3 .

As illustrated in FIGS. 1 to 4 , the disk composition 10 for diagnosis according to the present invention may include a plurality of disks, including a first disk 100 and a second disk 200 . In FIGS. 1 to 4 , a disk composition 10 for diagnosis consisting of 10 disks is illustrated. However, the number of disk compositions 10 for diagnosis according to the present invention is not limited to the drawings, and the present invention may be composed of various numbers of disks.

Furthermore, the description of the first disk 100 and the second disk 200 in this specification can also be applied in the same manner to other disks constituting the disk composition 10 for diagnosis according to the present invention.

As illustrated in Figure 1, the first disk 100 and the second disk 200 may be adjacent to each other and disposed in parallel.

Moreover, FIG. 1 illustrates the appearance of the first receiving part 110 and the second receiving part 210 respectively defined in the first tray 100 and the second tray 200.

And, as illustrated in FIG. 2 , the first protruding part 120 and the second protruding part 220 having downward protruding shapes may be defined in the first tray 100 and the second tray 200 respectively. Here, as illustrated in FIG. 1 , the upper portions of the first protruding part 120 and the second protruding part 220 have a downwardly concave structure, and therefore a space may be defined in the corresponding first protruding part 120 and the second protruding part 220 within. The space may be the first receiving part 110 and the second receiving part 210 .

According to the present invention, the disk composition for diagnosis 10 may further include components for connecting a plurality of disks constituting the disk composition for diagnosis. That is, disk compositions for diagnosis 10 may comprise a connection unit disposed between any two disks and having one end portion connected to one disk and another end portion connected to the other disk. Therefore, the two disks are connected to each other. As an example in FIGS. 1 to 4 , the connection unit 300 is illustrated as being disposed between the first disk 100 and the second disk 200 . That is, the disk composition 10 for diagnosis according to the present invention has a structure in which a plurality of disks are arranged in parallel and spaced apart from each other at regular intervals, and a connection unit is provided between the plurality of disks to connect the plurality of disks. Moreover, as illustrated in FIGS. 1 to 3 , a plurality of disks including the first disk 100 and the second disk 200 may be connected in parallel to each other in the width W direction of the disks through the connection unit 300 . Therefore, the second tray 200 can be disposed on the side portion of the first tray 100 in the width W direction with the connection unit 300 disposed therebetween.

According to the present invention, since the disks are connected to each other by the connection unit, the disks constituting the disk composition for diagnosis can be loaded once on an automated device for sample reaction. Therefore, steps and time can be significantly reduced when compared to the case where disks for sample reactions are loaded separately on the automated device. For example, in the case where ten disks are loaded on the automation device, the steps of mounting the ten disks on a single frame one by one and then loading the frame on the automation device are required according to the related art. However, in the case of manufacturing a disk composition for diagnosis in which ten disks are connected to each other by the connection unit according to the present invention, it is sufficient to load the disk composition for diagnosis on the automation device at once, and therefore significantly This greatly reduces the steps and time required for sample reactions in automated devices.

Also, according to the present invention, since a separate frame for accommodating the disk is not required during loading of the disk on the automation device, the space occupied by the frame within the automation device is removed, and therefore the internal space utilization within the automation device can be improved maximize.

Here, as illustrated in Figures 1 to 3, the disk composition according to the present invention Each of the plurality of disks 10 may have an elongated rod shape. For example, as illustrated in FIGS. 3 and 4 , each of the first disk 100 and the second disk 200 may have an elongated rod shape having a predetermined width W, a predetermined thickness t, and a predetermined length L. The first disk 100 may have a predetermined length L. And the second disk has an elongated rod shape can be understood to mean that the first disk and the second disk have a significantly larger length L when compared to the width W and thickness t.

More preferably, the ratio of the length L to the width W in each of the first tray 100 and the second tray 200 may be 10 to 30, and the ratio of the length L to the thickness t may also be 20 to 40. Here, the plurality of disks constituting the disk composition 10 according to the present invention may have the same size and shape. Therefore, the above description of the width, thickness and length of each of the first and second disks also applies in the same manner to all disks making up the disk composition. Referring again to FIGS. 1 to 4 , multiple connection units according to the present invention may be disposed between two disks. For example, as illustrated in FIGS. 1 to 3 , two connection units 300 are disposed between the first disk 100 and the second disk 200 . That is, two connection units may be respectively provided in the upper region and the lower region of each of the first tray 100 and the second tray 200 . However, different from the above description, the three connection units 300 may be respectively provided in the upper area, the middle area and the lower area of each of the first tray 100 and the second tray 200 .

Here, as illustrated in FIGS. 5 to 16 , the connection unit 300 of the disk composition 10 for diagnosis according to the present invention may have a notch part 300 a having a concave shape at which the connection unit is Have a smaller thickness than the thickness of other areas of the connection unit.

Depending on the state of use of the diagnostic disk composition of the present invention, some of the disks of the diagnostic disk composition may need to be separated. Here, since the recess in the connection unit 300 has a relatively small thickness when compared to other areas of the connection unit 300 The mouth part 300a is easier to break, so some of the disks of the diagnostic disk composition can be easily separated according to the usage state of the diagnostic disk composition.

As illustrated in FIGS. 5 to 8 , according to the first embodiment of the present invention, the notch part 300 a of the connection unit 300 may be defined in the central portion of the connection unit 300 in the length L direction. Here, the notch part 300a may be defined in only the top surface or only the bottom surface of the connection unit 300 as illustrated in FIGS. 5 and 7 , and the notch part 300a may also be defined in FIGS. 6 and 8 is defined in both the top surface and the bottom surface of the connection unit 300 . In the case where the notch part 300a is defined in only the top surface or only the bottom surface of the connection unit 300, the connection unit 300 can be easily cut if necessary while maintaining the durability of the connection unit 300 as much as possible. In the case where the notch component 300a is defined in both the top and bottom surfaces of the connection unit 300, the connection unit 300 can be quickly cut if necessary.

Here, the notch part 300a according to the first embodiment of the present invention may have a V shape as illustrated in FIGS. 5 and 6 . In the case where the notch part 300a has a V-shape, since stress accumulation occurs in the "V-shaped" valley region in which the shape of the notch part 300a is significantly changed, the connection unit 300 may be configured at the notch part 300a as necessary. May be cut quickly.

On the other hand, the notch part 300a according to the first embodiment of the present invention may have a U shape as illustrated in FIGS. 7 and 8 . Here, the "U-shape" may be understood as a concept that includes a lower end portion defined with an angular shape as illustrated in FIGS. 7 and 8 and a lower end portion defined with a circular shape. In the case where the notch part 300a has a U shape, unlike the case of a V shape, since stress accumulation occurs relatively weakly or does not occur at the notch part 300a, the connection unit 300 can be easily cut if necessary, while The durability of the connection unit 300 is maintained as much as possible.

Also, as illustrated in FIGS. 9 to 12 , according to the second embodiment of the present invention, the notch part 300 a of the connection unit 300 may be defined in both end portions of the connection unit 300 in the length L direction. That is, according to the second embodiment of the present invention, the notch part 300a of the connection unit 300 can be directly connected to the first tray 100 and the second tray 200. Here, the notch part 300a may be defined in only the top surface or only the bottom surface of the connection unit 300 as illustrated in FIGS. 9 and 11 , and the notch part 300a may also be defined in FIGS. 10 and 12 is defined in each of the top surface and the bottom surface of the connection unit 300 . In the case where the notch part 300a is defined in only the top surface and only the bottom surface of the connection unit 300 and in the case where the notch part 300a is defined in each of the top surface and the bottom surface of the connection unit 300 The description of the effect in the case is replaced by the above description of the effect in the first embodiment of the invention.

Moreover, each of the notch parts 300a according to the second embodiment of the present invention may have a V shape as illustrated in FIGS. 9 and 10 or may also have a U shape as illustrated in FIGS. 11 and 12 . The description of the effect in the case where the notch part 300a has a V-shape and the case in which the notch part 300a has a U-shape is also replaced by the above description of the effect in the first embodiment of the invention.

Also, as illustrated in FIGS. 13 to 16 , according to the third embodiment of the present invention, the notch member 300 a is defined in each of the areas spaced from the corresponding point to the center of the connection unit 300 in the length L direction. Among them, the connection unit 300 is connected to the first disk 100 and the second disk 200 at the corresponding points. Here, the notch part 300a may be defined in only the top surface or only the bottom surface of the connection unit 300 as illustrated in FIGS. 13 and 15 , and the notch part 300a may also be defined in FIGS. 14 and 16 is defined in each of the top surface and the bottom surface of the connection unit 300 . In the case where the notch part 300a is defined in only the top surface and only the bottom surface of the connection unit 300 and in the case where the notch part 300a is defined in each of the top surface and the bottom surface of the connection unit 300 The description of the effect in the case is replaced by the above description of the effect in the first embodiment of the invention.

Moreover, each of the notch parts 300a according to the third embodiment of the present invention may have a V shape as illustrated in FIGS. 13 and 14 or may also have a U shape as illustrated in FIGS. 15 and 16 . The description of the effect in the case where the notch part 300a has a V-shape and the case in which the notch part 300a has a U-shape is also replaced by the above description of the effect in the first embodiment of the invention.

Here, in the case where the notch part 300a is defined in both the top surface and the bottom surface of the connection unit 300 according to the present invention, the notch part defined in the bottom surface of the connection unit 300 is defined in a at a position corresponding to the position of the notch component defined in the top surface of the connection unit 300, as illustrated in Figures 6, 8, 10, 12, 14 and 16. In this case, the cutting characteristics of the connection unit 300 at the notch part can be maximized.

However, unlike the above, the surface of the connection unit 300 according to the present invention may have a flat shape in which the notch part is not defined.

Here, the connection unit 300 according to the present invention may be made of a material that has a hardness such that the material can be cut by a person according to a state of use while having a hardness sufficient to enable the connection between the disks to be maintained.

Also, the connection unit 300 according to the present invention may be made of a material that has such a property that when a region of the connection unit 300 is impacted, the region plastically deforms to a certain degree or a higher degree and then breaks without transmitting the impact. Ductility and brittleness to areas other than the impacted area.

Also, the connection unit 300 according to the present invention may be made of a material that is biocompatible so that even if it comes into contact with a sample disposed in a chip for diagnosis, a reaction does not occur, and therefore the diagnosis of the sample The results are not affected.

For example, the connection unit 300 according to the present invention may include one or more materials selected from the group consisting of polycarbonate, polyethylene, polypropylene, and ABS. More preferably, the connection unit 300 may be made of polycarbonate, polyethylene or polypropylene, or may be made of a mixture of polycarbonate and ABS. Here, the disk and the connection unit of the disk composition for diagnosis according to the present invention may have the same material. In the case where the disk and the connecting unit are of the same material, efficiency can be improved when manufacturing the disk composition.

More preferably, the connection unit 300 according to the present invention may be made of ABS material. In particular, ABS materials are less ductile and more brittle when compared to polypropylene or the like. Therefore, in the case where the connection unit 300 is made of such ABS material, the connection unit 300 can be easily cut to meet the user's needs, and thus the separation between the disks can be easily performed.

Specifically, as explained above, each of the plurality of disks including the first disk and the second disk in the disk composition according to the present invention has an elongated rod shape. In the case where a plurality of disks having an elongated rod shape are connected to each other in the width W direction of the disk (see FIGS. 3 and 4 ) by the connection unit 300 having an ABS material, the ease of separation of the disks can be determined according to the user. needs are significantly maximized.

That is, according to the present invention, (i) since the plurality of disks constituting the disk composition are connected in parallel to each other by connecting units in the width direction of the disk (that is, in one dimension), only along the width direction of the disk The connecting units provided require cutting in order to separate the disks. Therefore, when compared to a case in which a plurality of disks are connected parallel to each other in the thickness direction or longitudinal direction of the disk and in the width direction of the disk (that is, in both dimensions) At this time, the disk can be separated further easily.

Furthermore, according to the present invention, (ii) since the connection unit of the connection pad is made of ABS material with low ductility and high brittleness, the connection unit can be broken without the user exerting a large amount of force. Therefore, when compared to the case where the connection unit is made of a material other than ABS material, the disk can be separated further easily.

Furthermore, according to the present invention, (iii) since each of the plurality of disks constituting the disk composition has an elongated rod shape, the user can cut the connecting unit in a state where the user can easily hold the disk in his hand. Therefore, when compared to a case in which each of the disks does not have an elongated rod shape but has a cuboid shape with small differences between width, thickness, and length, the disks can be separated further easily.

Also, the connection unit 300 according to the present invention may be made of the same material as the disk 100 and the disk 200 constituting the disk composition 10. In this case, the types of materials and processes required to manufacture disk compositions according to the present invention can be minimized.

However, unlike the above, the connection unit 300 according to the present invention may be made of a different material from that of each of the disk 100 and the disk 200 constituting the disk composition 10 . In this case, due to the boundary between the disk 100 and the disk 200 and the connection unit 300, when a person applies force to the connection unit to cut the connection unit according to the usage state, impact is not applied to the disk 100 and the disk 200. Therefore, the problem of damage of the disk 100 and the disk 200 occurring during cutting of the connection unit 300 can be solved.

Here, the disc composition for diagnosis according to the present invention may be a disc composition for diagnosis of allergy. That is, the present invention can be applied to the field of allergy diagnosis, in which a membrane coated with an allergen (for example, an allergy-causing material such as an antigen or the like) is placed in a tray, and thus the presence of an allergy can be diagnosed Or it doesn't exist.

And, as described above, each of the first tray 100 and the second tray 200 The ratio of length L to width W in one may be 10 to 30. In the case where the ratio of the length L to the width W is less than 10, the number of allergens disposed within the tray must be limited, and therefore it is impossible to realize a highly integrated tray for diagnosis. On the other hand, in the case where the ratio of the length L to the width W is greater than 30, the length of the disk becomes relatively too long, and therefore quality problems of the disk may occur. For example, in a case where the ratio of the length L to the width W is greater than 30, a problem may occur in which the disk bends without maintaining a straight shape or the like. Therefore, the above feature, in which the ratio of the length L to the width W in each of the first disk 100 and the second disk 200 is from 10 to 30, can be considered not only an option but also of crucial significance.

Although the present invention has been described through the specific embodiments and drawings described above, the present invention is not limited thereto, and it is obvious that those skilled in the art to which the present invention belongs can understand the technical ideas of the present invention and the appended patent scope, etc. Make various changes and modifications within the effective scope.

10: Disk composition for diagnosis

100: first set

110: First containing part

200:Second set

210: Second receiving part

Claims (8)

A disk composition for diagnosis, including: a first disk and a second disk, each of which has a receiving part for receiving a diaphragm for diagnosis, and the first disk and the second disk are parallel to each other provided; and a connection unit provided between the first disk and the second disk and having one end portion connected to the first disk and another end portion connected to the second disk, wherein Each of the first disk and the second disk has an elongated rod shape having a predetermined width (W), a predetermined thickness (t), and a predetermined length (L), and the second disk is in the first The disk is disposed on the side portion of the first disk in the width (W) direction, wherein the connection unit is disposed between the first disk and the second disk, and the connection unit is made of ABS , wherein the connecting unit includes a recessed part having a concave shape, the connecting unit has a smaller thickness at the recessed part than a thickness of other areas of the connecting unit, and wherein the recessed part is defined at each of the two end portions of the connecting unit in the length (L) direction of the connecting unit. The disk composition for diagnosis as claimed in claim 1, wherein the ratio of the length (L) to the width (W) in each of the first disk and the second disk is 10 to 30, and the ratio of the length (L) to the thickness (t) in each of the first disk and the second disk is from 20 to 40. The disk composition for diagnosis as claimed in claim 1, wherein said notch The components have a V-shaped cross-section. The disk composition for diagnosis as claimed in claim 1, wherein the notch part has a U-shaped cross-section. The disk composition for diagnosis as claimed in claim 1, wherein the notch part is defined only in the top surface or the bottom surface of the connection unit. The disk composition for diagnosis according to claim 1, wherein the disk composition for diagnosis is a disk composition for diagnosis of allergy. A disk composition for diagnosis, comprising: a first disk and a second disk, each of which has a receiving part for receiving a diaphragm for diagnosis, and the first disk and the second disk are parallel to each other provided; and a connection unit provided between the first disk and the second disk and having one end portion connected to the first disk and another end portion connected to the second disk, wherein Each of the first disk and the second disk has an elongated rod shape having a predetermined width (W), a predetermined thickness (t), and a predetermined length (L), and the second disk is in the first The disk is disposed on the side portion of the first disk in the width (W) direction, wherein the connection unit is disposed between the first disk and the second disk, and the connection unit is made of ABS , wherein the connecting unit includes a recessed component having a concave shape, the connecting unit has a smaller thickness at the recessed component than a thickness at other areas of the connecting unit, wherein the recessed component is at The length (L) direction of the connection unit is defined in each of the areas spaced from the corresponding point to the center of the connection unit , the connection unit is connected to the first disk and the second disk at the corresponding points. A disk composition for diagnosis, comprising: a first disk and a second disk, each of which has a receiving part for receiving a diaphragm for diagnosis, and the first disk and the second disk are parallel to each other provided; and a connection unit provided between the first disk and the second disk and having one end portion connected to the first disk and another end portion connected to the second disk, wherein Each of the first disk and the second disk has an elongated rod shape having a predetermined width (W), a predetermined thickness (t), and a predetermined length (L), and the second disk is in the first The disk is disposed on the side portion of the first disk in the width (W) direction, wherein the connection unit is disposed between the first disk and the second disk, and the connection unit is made of ABS , wherein the connection unit includes a recessed part having a concave shape, the connection unit having a smaller thickness at the recessed part than a thickness of other areas of the connection unit, wherein the recessed part defines In each of the top surface and the bottom surface of the connection unit, and wherein the notch component defined in the bottom surface of the connection unit is disposed at a position corresponding to The location of the notch component defined in the top surface of the connection unit.

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