TWI808668B - 乾式敷料 - Google Patents
乾式敷料 Download PDFInfo
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- TWI808668B TWI808668B TW111107863A TW111107863A TWI808668B TW I808668 B TWI808668 B TW I808668B TW 111107863 A TW111107863 A TW 111107863A TW 111107863 A TW111107863 A TW 111107863A TW I808668 B TWI808668 B TW I808668B
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- hydrocolloid
- hydrophilic colloid
- dry dressing
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- 239000000416 hydrocolloid Substances 0.000 claims abstract description 49
- 239000004372 Polyvinyl alcohol Substances 0.000 claims abstract description 32
- 229920002451 polyvinyl alcohol Polymers 0.000 claims abstract description 32
- 229920000036 polyvinylpyrrolidone Polymers 0.000 claims abstract description 32
- 239000001267 polyvinylpyrrolidone Substances 0.000 claims abstract description 32
- 235000013855 polyvinylpyrrolidone Nutrition 0.000 claims abstract description 32
- 235000015097 nutrients Nutrition 0.000 claims abstract description 31
- 239000000758 substrate Substances 0.000 claims abstract description 14
- 239000000084 colloidal system Substances 0.000 claims description 21
- 239000000203 mixture Substances 0.000 claims description 19
- 229920002134 Carboxymethyl cellulose Polymers 0.000 claims description 9
- 239000001768 carboxy methyl cellulose Substances 0.000 claims description 8
- 235000010948 carboxy methyl cellulose Nutrition 0.000 claims description 8
- 239000008112 carboxymethyl-cellulose Substances 0.000 claims description 8
- 239000000230 xanthan gum Substances 0.000 claims description 7
- 229920001285 xanthan gum Polymers 0.000 claims description 7
- 235000010493 xanthan gum Nutrition 0.000 claims description 7
- 229940082509 xanthan gum Drugs 0.000 claims description 7
- 229920002907 Guar gum Polymers 0.000 claims description 6
- 239000000665 guar gum Substances 0.000 claims description 6
- 235000010417 guar gum Nutrition 0.000 claims description 6
- 229960002154 guar gum Drugs 0.000 claims description 6
- 150000001413 amino acids Chemical class 0.000 claims description 3
- -1 dispensing Substances 0.000 claims description 3
- 229910021645 metal ion Inorganic materials 0.000 claims description 3
- 229920001495 poly(sodium acrylate) polymer Polymers 0.000 claims description 3
- 108090000623 proteins and genes Proteins 0.000 claims description 3
- 102000004169 proteins and genes Human genes 0.000 claims description 3
- NNMHYFLPFNGQFZ-UHFFFAOYSA-M sodium polyacrylate Chemical compound [Na+].[O-]C(=O)C=C NNMHYFLPFNGQFZ-UHFFFAOYSA-M 0.000 claims description 3
- 239000011248 coating agent Substances 0.000 claims description 2
- 238000000576 coating method Methods 0.000 claims description 2
- 238000007639 printing Methods 0.000 claims description 2
- 238000005470 impregnation Methods 0.000 claims 1
- 238000007650 screen-printing Methods 0.000 claims 1
- 239000007921 spray Substances 0.000 claims 1
- 239000004615 ingredient Substances 0.000 abstract description 6
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 29
- JEGUKCSWCFPDGT-UHFFFAOYSA-N h2o hydrate Chemical compound O.O JEGUKCSWCFPDGT-UHFFFAOYSA-N 0.000 description 15
- 108010004729 Phycoerythrin Proteins 0.000 description 11
- 229910052740 iodine Inorganic materials 0.000 description 10
- 239000011630 iodine Substances 0.000 description 10
- ZCYVEMRRCGMTRW-UHFFFAOYSA-N 7553-56-2 Chemical compound [I] ZCYVEMRRCGMTRW-UHFFFAOYSA-N 0.000 description 9
- 239000000654 additive Substances 0.000 description 9
- 230000000996 additive effect Effects 0.000 description 8
- 238000001035 drying Methods 0.000 description 7
- 239000011734 sodium Substances 0.000 description 7
- 230000000172 allergic effect Effects 0.000 description 4
- 208000010668 atopic eczema Diseases 0.000 description 4
- 238000000034 method Methods 0.000 description 4
- 238000009472 formulation Methods 0.000 description 3
- 239000003755 preservative agent Substances 0.000 description 3
- 239000000341 volatile oil Substances 0.000 description 3
- KIUKXJAPPMFGSW-DNGZLQJQSA-N (2S,3S,4S,5R,6R)-6-[(2S,3R,4R,5S,6R)-3-Acetamido-2-[(2S,3S,4R,5R,6R)-6-[(2R,3R,4R,5S,6R)-3-acetamido-2,5-dihydroxy-6-(hydroxymethyl)oxan-4-yl]oxy-2-carboxy-4,5-dihydroxyoxan-3-yl]oxy-5-hydroxy-6-(hydroxymethyl)oxan-4-yl]oxy-3,4,5-trihydroxyoxane-2-carboxylic acid Chemical compound CC(=O)N[C@H]1[C@H](O)O[C@H](CO)[C@@H](O)[C@@H]1O[C@H]1[C@H](O)[C@@H](O)[C@H](O[C@H]2[C@@H]([C@@H](O[C@H]3[C@@H]([C@@H](O)[C@H](O)[C@H](O3)C(O)=O)O)[C@H](O)[C@@H](CO)O2)NC(C)=O)[C@@H](C(O)=O)O1 KIUKXJAPPMFGSW-DNGZLQJQSA-N 0.000 description 2
- FYGDTMLNYKFZSV-URKRLVJHSA-N (2s,3r,4s,5s,6r)-2-[(2r,4r,5r,6s)-4,5-dihydroxy-2-(hydroxymethyl)-6-[(2r,4r,5r,6s)-4,5,6-trihydroxy-2-(hydroxymethyl)oxan-3-yl]oxyoxan-3-yl]oxy-6-(hydroxymethyl)oxane-3,4,5-triol Chemical compound O[C@@H]1[C@@H](O)[C@H](O)[C@@H](CO)O[C@H]1OC1[C@@H](CO)O[C@@H](OC2[C@H](O[C@H](O)[C@H](O)[C@H]2O)CO)[C@H](O)[C@H]1O FYGDTMLNYKFZSV-URKRLVJHSA-N 0.000 description 2
- 229920002498 Beta-glucan Polymers 0.000 description 2
- OYPRJOBELJOOCE-UHFFFAOYSA-N Calcium Chemical compound [Ca] OYPRJOBELJOOCE-UHFFFAOYSA-N 0.000 description 2
- DGAQECJNVWCQMB-PUAWFVPOSA-M Ilexoside XXIX Chemical compound C[C@@H]1CC[C@@]2(CC[C@@]3(C(=CC[C@H]4[C@]3(CC[C@@H]5[C@@]4(CC[C@@H](C5(C)C)OS(=O)(=O)[O-])C)C)[C@@H]2[C@]1(C)O)C)C(=O)O[C@H]6[C@@H]([C@H]([C@@H]([C@H](O6)CO)O)O)O.[Na+] DGAQECJNVWCQMB-PUAWFVPOSA-M 0.000 description 2
- FYYHWMGAXLPEAU-UHFFFAOYSA-N Magnesium Chemical compound [Mg] FYYHWMGAXLPEAU-UHFFFAOYSA-N 0.000 description 2
- ZLMJMSJWJFRBEC-UHFFFAOYSA-N Potassium Chemical compound [K] ZLMJMSJWJFRBEC-UHFFFAOYSA-N 0.000 description 2
- 238000010521 absorption reaction Methods 0.000 description 2
- 239000004480 active ingredient Substances 0.000 description 2
- 239000011575 calcium Substances 0.000 description 2
- 229910052791 calcium Inorganic materials 0.000 description 2
- 230000000694 effects Effects 0.000 description 2
- 239000000284 extract Substances 0.000 description 2
- 229920002674 hyaluronan Polymers 0.000 description 2
- 229960003160 hyaluronic acid Drugs 0.000 description 2
- 239000007788 liquid Substances 0.000 description 2
- 239000011777 magnesium Substances 0.000 description 2
- 229910052749 magnesium Inorganic materials 0.000 description 2
- 238000004519 manufacturing process Methods 0.000 description 2
- 239000011591 potassium Substances 0.000 description 2
- 229910052700 potassium Inorganic materials 0.000 description 2
- 238000004321 preservation Methods 0.000 description 2
- 230000036555 skin type Effects 0.000 description 2
- 229910052708 sodium Inorganic materials 0.000 description 2
- 238000003860 storage Methods 0.000 description 2
- 230000008961 swelling Effects 0.000 description 2
- 238000012360 testing method Methods 0.000 description 2
- 241000894006 Bacteria Species 0.000 description 1
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 description 1
- 241000282372 Panthera onca Species 0.000 description 1
- 239000003963 antioxidant agent Substances 0.000 description 1
- 238000006243 chemical reaction Methods 0.000 description 1
- 239000002537 cosmetic Substances 0.000 description 1
- 229920006037 cross link polymer Polymers 0.000 description 1
- 230000006866 deterioration Effects 0.000 description 1
- 238000011156 evaluation Methods 0.000 description 1
- 238000002474 experimental method Methods 0.000 description 1
- 239000012530 fluid Substances 0.000 description 1
- 238000007654 immersion Methods 0.000 description 1
- 150000002500 ions Chemical class 0.000 description 1
- 238000012986 modification Methods 0.000 description 1
- 230000004048 modification Effects 0.000 description 1
- 230000007935 neutral effect Effects 0.000 description 1
- 230000003204 osmotic effect Effects 0.000 description 1
- 238000004806 packaging method and process Methods 0.000 description 1
- 238000004904 shortening Methods 0.000 description 1
- 230000037384 skin absorption Effects 0.000 description 1
- 231100000274 skin absorption Toxicity 0.000 description 1
- 238000002791 soaking Methods 0.000 description 1
- 239000007787 solid Substances 0.000 description 1
- 238000009736 wetting Methods 0.000 description 1
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Abstract
一種乾式敷料，用以貼附於人體皮膚。乾式敷料包含一襯底層以及一接觸層。接觸層設置於襯底層上。接觸層包含一親水膠體以及一營養素。營養素混合於親水膠體。親水膠體乾燥地形成於襯底層上。親水膠體的成分包含聚乙烯醇與聚乙烯吡咯烷酮，親水膠體的成分中聚乙烯醇與聚乙烯吡咯烷酮佔親水膠體的重量比例為96%以上，且親水膠體的成分中聚乙烯醇與聚乙烯吡咯烷酮的重量比值為0.725到0.785。
Description
本發明係關於一種敷料，特別是一種具有乾燥親水膠體的乾式敷料。
醫療或美容用途的敷料係用來貼附於皮膚，以達到治療或保養皮膚的功效。由於這些敷料內含的營養素大多需要以液體為載體來供皮膚吸收，因此這些敷料往往是浸有精華液，以濕潤的形式密封在包裝中以待使用。
然而，為避免濕式敷料的精華液內茲生細菌，精華液常會含有防腐劑，在使用敷料時容易造成特定體質者過敏不適。再者，濕式敷料亦含有一定的重量，不易攜帶。萬一在攜帶過程中不小心受到擠壓造成包裝破裂，除了需要另行清潔流出的精華液，包裝破裂的濕式敷料也難以再供使用，相當不便。
本發明在於提供一種乾式敷料，便於攜帶與儲放，亦不易造成使用者的過敏不適。
本發明之一實施例所揭露之乾式敷料，用以貼附於人體皮膚，乾式敷料包含一襯底層以及一接觸層。接觸層設置於襯底層上。接觸層包含一親水膠體以及一營養素。營養素混合於親水膠體。親水膠體乾燥地形成於襯底層上。親水膠體的成分包含聚乙烯醇與聚乙烯吡咯烷酮，且親水膠體的成分中聚乙烯醇與聚乙烯吡咯烷酮佔親水膠體的重量比例為96%以上，且親水膠體的成分中聚乙烯醇與聚乙烯吡咯烷酮的重量比值為0.725到0.785。
根據上述實施例所揭露的乾式敷料，藉由將混合有營養素的親水膠體乾燥地形成於襯底層上，在沾濕使用前不必擔心重量過重或包裝破裂等問題，而有利於攜帶與儲放。此外，乾燥的乾式敷料也有利於保存，不需額外添加防腐劑，從而沒有容易造成特定膚質使用者過敏不適的問題。
此外，成分包含重量比值為0.725到0.785的聚乙烯醇與聚乙烯吡咯烷酮的親水膠體在2到3秒即可吸水膨脹完畢，不需過度等待親水膠體的吸水時間，並且親水膠體吸水後重量適中且不易在皮膚上滑動，適合供使用者敷用以釋放營養素。
以上關於本發明內容的說明及以下實施方式的說明係用以示範與解釋本發明的原理，並且提供本發明的專利申請範圍更進一步的解釋。
以下將介紹本發明之一實施例，請參照圖1，係根據本發明之一實施例所繪示之乾式敷料的側視示意圖。
本實施例提供一種乾式敷料10，包含一襯底層100以及一接觸層200。接觸層200設置於襯底層100上，且接觸層200包含在同一層中彼此混合的一親水膠體210以及一營養素220。
具體來說，營養素220在濕式狀態下混合於親水膠體210，以能充分地分布在親水膠體210中，但本發明不以此為限，營養素亦可在乾式狀態下混合於親水膠體。包含有彼此混合之親水膠體210與營養素220的接觸層200例如以網印、塗佈、點膠、噴印與含浸等方式印刷在襯底層100上，如圖2所示；並藉由將襯底層100與接觸層200放置於乾燥環境下讓親水膠體210乾燥地形成於襯底層100上，如圖3所示，水分WW向上蒸發，其中圖2至圖3係圖1之乾式敷料的製造過程。
乾式敷料10例如用以沾濕後貼附於人體皮膚。請一併參照圖4，係圖1之乾式敷料的使用過程。如圖4所示，使用者先在乾式敷料10上添加水分或精油WE，接著會如圖2所示，親水膠體210吸水後膨脹並形成高滲透壓，使得親水膠體210內部的親水交聯聚合物產生流體壓力將營養素220輸送出去，而可讓吸水後的乾式敷料10貼附於人體皮膚以釋放出營養素220。其中，以乾式敷料含有約4到5公克(g)的親水膠體為例，在分別添加7.5、15、22.5公克的水分30秒後，分別為吸收全部水分、殘留約3到4公克的水分以及殘留約6到7公克的水分，因此可得知每單位的親水膠體吸收固定量的水分，不會過度吸水。
親水膠體210的成分包含聚乙烯醇(PVA)與聚乙烯吡咯烷酮(PVP)，藉由PVA來提供親水膠體210的強度，而以PVP來提供親水膠體210的親水性。具體來說，親水膠體210的成分中，PVA與PVP佔親水膠體210的重量比例為96%以上，且PVA與PVP的重量比值可為0.725到0.785，以在成型性與親水性之間取得平衡，能在濕式狀態下保持一定流動性的同時仍能固持營養素220。
下表為乾式敷料的七種配方，其中親水膠體皆為約5公克，PVA與PVP佔親水膠體的重量比例皆為96%，且這七種配方的營養素皆含有能對碘溶液進行還原作用的藻紅素。使用藻紅素的用意在於測試這七種配方的乾式敷料在吸水後是否容易釋放出帶有藻紅素的營養素，藉由將這七種配方的乾式敷料吸水後浸泡在碘溶液中，觀察被釋放出的藻紅素將深紫色的碘溶液還原的透明程度，來判斷營養素是否釋放完全，透明程度越高則代表越容易釋放出營養素。
| PVA與PVP的重量比值 | 添加22.5g的水分 | 吸水後狀態 | 是否易於釋放營養素 (以藻紅素為例) | |
| 配方1 | 0.70 | 2秒鐘完全吸收 | 易展開敷用，但過重且易滑落 | 易 |
| 配方2 | 0.72 | 2秒鐘吸收膨脹，並殘留3g水分 | 易展開敷用，但過重且易滑落 | 易 |
| 配方3 | 0.725 | 2秒鐘吸收膨脹，並殘留6g水分 | 易展開敷用，重量適中且不易滑動 | 易 |
| 配方4 | 0.75 | 2秒鐘吸收膨脹，並殘留6.5g水分 | 易展開敷用，重量適中且不易滑動 | 易 |
| 配方5 | 0.785 | 3秒鐘吸收膨脹，並殘留7g水分 | 易展開敷用，重量適中且不易滑動 | 易 |
| 配方6 | 0.79 | 7秒鐘吸收膨脹，並殘留10.5g水分 | 難以展開敷用 | 不易 |
| 配方7 | 0.81 | 13秒鐘吸收膨脹，並殘留16g水分 | 難以展開敷用，且有悶熱感 | 不易 |
根據以上配方1~配方7的比較表，可得知當PVA與PVP的重量比值為0.725到0.785時，親水膠體210吸水後膨脹的時間可在2到3秒內，適合讓使用者添加水分或精油WE後使用，不需過度等待親水膠體210的吸水時間。若是PVA與PVP的重量比值為未滿0.725時（即PVP過多），則此重量比值的PVA與PVP混合物需要吸收相當程度的水分才能膨脹，且此重量比值的PVA與PVP混合物在吸收相當程度的水分後會過重，造成使用者敷用時的不適感，亦會過度呈液態狀而難以固定於襯底層上以供敷用。若是PVA與PVP的重量比值為超過0.785時（即PVA過多），則此重量比值的PVA與PVP混合物需要相當程度的時間才能吸水膨脹，且此重量比值的PVA與PVP混合物在吸水後會過度呈固態狀而難以難以展開敷用，甚至有悶熱感；此外，根據藻紅素對碘溶液進行還原作用的實驗可得知，PVA與PVP的重量比值為超過0.785時，內含有藻紅素的營養素不易被釋放出來以對碘溶液進行還原（變色）反應。
上述的PVA與PVP構成親水膠體210的基本成分，除此之外，親水膠體210的成分更可包含其他添加物以達到其他良好效果。具體來說，親水膠體210的成分更可包含聚丙烯酸鈉(PAA-Na)。少許的PAA-Na能增加親水膠體210的黏稠感，以提升乾式面膜10在沾濕後的手感。具體來說，親水膠體210的成分中，PAA-Na的整體重量佔比為0.2%到0.4%。
親水膠體210的成分更可包含黃原膠與瓜爾膠(Jaguar)，藉以增加親水膠體210膨脹後的強度，避免親水膠體210基本成分中的PVA與PVP遇到特定離子或pH值過高或過低之成分後產生癱垮的現象，並進而增加親水膠體210吸水的膨脹效果，和提升親水膠體210膨脹後的滑潤手感。具體來說，親水膠體210的成分中，黃原膠的整體重量佔比為0.4%到0.5%，而瓜爾膠的整體重量佔比為0.05%到0.2%。
PAA-Na、黃原膠與瓜爾膠的配方可如下表所示，並附上六位人員敷感測試，其中以觸感作為滿意度的優先評估序位，其次為滑感與澎潤感。滿意度由高至低依序為添加物配方Y、添加物配方X與添加物配方Z，且添加物配方Z的滿意度過低而被判定為不合格。
| 添加物配方整體重量佔比 | 敷感 | ||||||
| PAA-Na | 黃原膠 | 瓜爾膠 | 人員 | 觸感 | 滑感 | 澎潤感 | |
| 添加物配方X | 0.2% | 0.45% | 0.08% | A | 舒適 | 無滑感 | 有 |
| B | 舒適 | 無滑感 | 有 | ||||
| C | 舒適 | 無滑感 | 有 | ||||
| D | 舒適 | 無滑感 | 有 | ||||
| E | 舒適 | 無滑感 | 有 | ||||
| F | 舒適 | 無滑感 | 有 | ||||
| 添加物配方Y | 0.4% | 0.47% | 0.179% | A | 舒適 | 有 | 有 |
| B | 舒適 | 有 | 有 | ||||
| C | 舒適 | 有 | 有 | ||||
| D | 舒適 | 有 | 有 | ||||
| E | 舒適 | 有 | 有 | ||||
| F | 舒適 | 有 | 有 | ||||
| 添加物配方Z | 0.53% | 0.38% | 0.08% | A | 太黏 | 無滑感 | 一點點 |
| B | 太黏 | 無滑感 | 一點點 | ||||
| C | 舒適 | 無滑感 | 一點點 | ||||
| D | 太黏 | 無滑感 | 一點點 | ||||
| E | 太黏 | 無滑感 | 一點點 | ||||
| F | 太黏 | 無滑感 | 一點點 |
親水膠體210的成分更可包含羧甲基纖維素(CMC)。親水膠體210的成分中，CMC的整體重量佔比可為0.3%以上。藉此可在乾燥親水膠體210的過程中，能夠以50°C以下的低溫條件達到6分鐘內快速乾燥的效果，以避免50°C以上的乾燥條件造成營養素220的變質。其中，CMC的整體重量佔比亦可為0.3%到2.0%，藉以在維持PVA與PVP之重量佔比與乾燥時間之間取得平衡；並且，若CMC的整體重量佔比超過2%時，對乾燥時間的縮短幅度不大，故將CMC的整體重量佔比進一步限定為0.3%到2.0%亦可節省成本。以下為CMC整體重量佔比與親水膠體210乾燥時間的關係表。
| CMC整體重量佔比 | ||||
| 0.0% | 0.3% | 1.5% | 2.0% | |
| 乾燥時間 (分鐘) | 8~10 | 5~6 | 3~3.5 | 3 |
營養素220的成分可例如包含玻尿酸、發酵β-葡聚醣與蛋白多醣萃取液等pH值中性的成分、蛋白質或胺基酸等活性成分(Active Ingredient)、藻紅素等抗氧化還原劑或鈣、鎂、鈉、鉀等金屬的離子。其中，可從以下實驗說明中得知藻紅素可保護皮膚並消除自由基：將含有藻紅素的乾式敷料浸泡在碘溶液中，藻紅素被釋放到碘溶液中進行還原作用，使得褐色的碘分子變成無色的碘離子，讓原本有色的碘溶液變透明。
根據上述實施例之乾式敷料，藉由將混合有營養素的親水膠體乾燥地形成於襯底層上，在沾濕使用前不必擔心重量過重或包裝破裂等問題，而有利於攜帶與儲放。此外，乾燥的乾式敷料也有利於保存，不需額外添加防腐劑，從而沒有容易造成特定膚質使用者過敏不適的問題。
此外，成分包含重量比值為0.725到0.785的PVA與PVP的親水膠體在2到3秒即可吸水膨脹完畢，不需過度等待親水膠體的吸水時間，並且親水膠體吸水後重量適中且不易在皮膚上滑動，適合供使用者敷用以釋放營養素。
根據本發明之乾式敷料，成分包含PVA與PVP的親水膠體可藉由吸收水分或精油而膨脹，並且適用於營養素的成分包含玻尿酸、發酵β-葡聚醣、蛋白多醣萃取液等中性成分。
根據本發明之乾式敷料，成分包含PVA與PVP之外還更包含黃原膠與瓜爾膠的親水膠體可藉由吸收水分而膨脹，並且適用於營養素的成分包含鈣、鎂、鈉、鉀等金屬離子或蛋白質、胺基酸等對酒精相容性差的活性成分。
雖然本發明以前述之諸項實施例揭露如上，然其並非用以限定本發明，任何熟習相像技藝者，在不脫離本發明之精神和範圍內，當可作些許之更動與潤飾，因此本發明之專利保護範圍須視本說明書所附之申請專利範圍所界定者為準。
10:乾式敷料
100:襯底層
200:接觸層
210:親水膠體
220:營養素
WW:水分
WE:精油
圖1係根據本發明之一實施例所繪示之乾式敷料的側視示意圖。
圖2至圖3係圖1之乾式敷料的製造過程。
圖4係圖1之乾式敷料的使用過程。
10:乾式敷料
100:襯底層
200:接觸層
210:親水膠體
220:營養素
Claims (10)
- 一種乾式敷料，用以貼附於人體皮膚，該乾式敷料包含：一襯底層；以及一接觸層，設置於該襯底層上，該接觸層包含一親水膠體以及一營養素，該營養素混合於該親水膠體，且該親水膠體乾燥地形成於該襯底層上；其中，該親水膠體的成分包含聚乙烯醇與聚乙烯吡咯烷酮，該親水膠體的成分中聚乙烯醇與聚乙烯吡咯烷酮佔該親水膠體的重量比例為96%以上，且該親水膠體的成分中聚乙烯醇與聚乙烯吡咯烷酮的重量比值為0.725到0.785。
- 如請求項1所述之乾式敷料，其中該接觸層以網印、塗佈、點膠、噴印或含浸方式印刷在該襯底層上。
- 如請求項1所述之乾式敷料，其中該親水膠體的成分更包含聚丙烯酸鈉。
- 如請求項3所述之乾式敷料，其中該親水膠體的成分中，聚丙烯酸鈉的重量佔比為0.2%到0.4%。
- 如請求項1所述之乾式敷料，其中該親水膠體的成分更包含黃原膠與瓜爾膠。
- 如請求項5所述之乾式敷料，其中該親水膠體的成分中，黃原膠的整體重量佔比為0.4%到0.5%，而瓜爾膠的整體重量佔比為0.05%到0.2%。
- 如請求項5所述之乾式敷料，其中該營養素的成分包含金屬離子。
- 如請求項1所述之乾式敷料，其中該親水膠體的成分更包含羧甲基纖維素。
- 如請求項8所述之乾式敷料，其中該親水膠體的成分中，羧甲基纖維素的重量佔比為0.3%以上。
- 如請求項1所述之乾式敷料，其中該營養素的成分包含蛋白質或胺基酸。
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