TWI688768B - 分析物濃度測定的正規化校正 - Google Patents

分析物濃度測定的正規化校正 Download PDF

Info

Publication number
TWI688768B
TWI688768B TW107124973A TW107124973A TWI688768B TW I688768 B TWI688768 B TW I688768B TW 107124973 A TW107124973 A TW 107124973A TW 107124973 A TW107124973 A TW 107124973A TW I688768 B TWI688768 B TW I688768B
Authority
TW
Taiwan
Prior art keywords
normalized
response
output signal
sample
analyte
Prior art date
Application number
TW107124973A
Other languages
English (en)
Chinese (zh)
Other versions
TW201840977A (zh
Inventor
伍煥平
Original Assignee
美商拜耳保健公司
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by 美商拜耳保健公司 filed Critical 美商拜耳保健公司
Publication of TW201840977A publication Critical patent/TW201840977A/zh
Application granted granted Critical
Publication of TWI688768B publication Critical patent/TWI688768B/zh

Links

Images

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N27/00—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
    • G01N27/26—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating electrochemical variables; by using electrolysis or electrophoresis
    • G01N27/28—Electrolytic cell components
    • G01N27/30—Electrodes, e.g. test electrodes; Half-cells
    • G01N27/327—Biochemical electrodes, e.g. electrical or mechanical details for in vitro measurements
    • G01N27/3271—Amperometric enzyme electrodes for analytes in body fluids, e.g. glucose in blood
    • G01N27/3274—Corrective measures, e.g. error detection, compensation for temperature or hematocrit, calibration
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/72—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving blood pigments, e.g. haemoglobin, bilirubin or other porphyrins; involving occult blood
    • G01N33/721—Haemoglobin
    • G01N33/723—Glycosylated haemoglobin
    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
    • G16B5/00—ICT specially adapted for modelling or simulations in systems biology, e.g. gene-regulatory networks, protein interaction networks or metabolic networks

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Hematology (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Molecular Biology (AREA)
  • Physics & Mathematics (AREA)
  • Immunology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biomedical Technology (AREA)
  • Urology & Nephrology (AREA)
  • Pathology (AREA)
  • General Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Microbiology (AREA)
  • Medicinal Chemistry (AREA)
  • Food Science & Technology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Electrochemistry (AREA)
  • Cell Biology (AREA)
  • Evolutionary Biology (AREA)
  • Physiology (AREA)
  • Bioinformatics & Computational Biology (AREA)
  • Biophysics (AREA)
  • Medical Informatics (AREA)
  • Spectroscopy & Molecular Physics (AREA)
  • Theoretical Computer Science (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
  • Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
  • Investigating Or Analysing Materials By Optical Means (AREA)
TW107124973A 2013-03-14 2014-03-13 分析物濃度測定的正規化校正 TWI688768B (zh)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201361782520P 2013-03-14 2013-03-14
US61/782,520 2013-03-14
??PCT/US14/21870 2014-03-07
PCT/US2014/021870 WO2014159077A1 (en) 2013-03-14 2014-03-07 Normalized calibration of analyte concentration determinations
WOPCT/US14/21870 2014-03-07

Publications (2)

Publication Number Publication Date
TW201840977A TW201840977A (zh) 2018-11-16
TWI688768B true TWI688768B (zh) 2020-03-21

Family

ID=50439487

Family Applications (2)

Application Number Title Priority Date Filing Date
TW107124973A TWI688768B (zh) 2013-03-14 2014-03-13 分析物濃度測定的正規化校正
TW103108988A TWI636252B (zh) 2013-03-14 2014-03-13 分析物濃度測定的正規化校正

Family Applications After (1)

Application Number Title Priority Date Filing Date
TW103108988A TWI636252B (zh) 2013-03-14 2014-03-13 分析物濃度測定的正規化校正

Country Status (10)

Country Link
US (2) US9958410B2 (enExample)
EP (2) EP2972396A1 (enExample)
JP (3) JP6305508B2 (enExample)
CN (1) CN105378484B (enExample)
CA (1) CA2902512A1 (enExample)
ES (1) ES2812806T3 (enExample)
HK (1) HK1221771A1 (enExample)
IL (1) IL240815A0 (enExample)
TW (2) TWI688768B (enExample)
WO (1) WO2014159077A1 (enExample)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2661053C1 (ru) * 2014-12-24 2018-07-11 Конинклейке Филипс Н.В. Измерения и калибровка, использующие колориметрические чувствительные элементы
WO2016185352A1 (en) 2015-05-15 2016-11-24 Ascensia Diabetes Care Holdings Ag Improved biosensor system analyte measurement
CN109073646A (zh) * 2016-05-13 2018-12-21 荣研化学株式会社 求取待测物在对比物中所占比例的方法、程序、存储介质及装置
CN109690304A (zh) 2016-07-12 2019-04-26 安晟信医疗科技控股公司 通过使用来自两个电极的交替输出信号进行电化学分析的方法
CA3036186C (en) * 2016-09-08 2021-03-30 Hemex Health, Inc. A point-of-care system for diagnosing disease, infection or condition of a patient
EP3548881A1 (en) 2016-12-05 2019-10-09 Ascensia Diabetes Care Holdings AG Risk factor monitoring
JP6829158B2 (ja) * 2017-07-18 2021-02-10 株式会社東芝 データ処理装置、データ処理方法、およびプログラム
WO2019147582A1 (en) * 2018-01-23 2019-08-01 Dexcom, Inc. Systems, devices, and methods to compensate for temperature effects on sensors
CN120093299A (zh) * 2021-10-12 2025-06-06 深圳硅基传感科技有限公司 分析物浓度的校准方法及分析物传感器
CN120381237A (zh) * 2024-01-27 2025-07-29 深圳硅基传感科技有限公司 用于分析物传感器的灵敏度衰减的校正方法、系统及介质
TWI893839B (zh) * 2024-06-07 2025-08-11 國立臺灣大學 糖化血色素百分比偵測方法以及使用該方法之電子裝置

Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TW200926203A (en) * 2007-12-04 2009-06-16 Univ Illinois Microcantilever heater-thermometer with integrated temperature-compensated strain sensor
WO2010059687A2 (en) * 2008-11-18 2010-05-27 The United States Of America, As Represented By The Secretary, Department Of Health And Human Services A semiconductor for measuring biological interactions
TW201138743A (en) * 2010-03-12 2011-11-16 Univ Illinois Implantable biomedical devices on bioresorbable substrates
TW201217783A (en) * 2010-09-15 2012-05-01 Mbio Diagnostics Inc System and method for detecting multiple molecules in one assay
TW201305548A (zh) * 2010-10-11 2013-02-01 Mbio Diagnostics Inc 用於細胞分析之系統及方法

Family Cites Families (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6153069A (en) 1995-02-09 2000-11-28 Tall Oak Ventures Apparatus for amperometric Diagnostic analysis
US5620579A (en) 1995-05-05 1997-04-15 Bayer Corporation Apparatus for reduction of bias in amperometric sensors
DK0958495T3 (da) 1997-02-06 2003-03-10 Therasense Inc In vitro analysand sensor med lille volumen
TW591230B (en) * 1997-10-14 2004-06-11 Bayer Ag Method for improving the accuracy of the semi-quantitative determination of analyte in fluid samples
US7723099B2 (en) * 2003-09-10 2010-05-25 Abbott Point Of Care Inc. Immunoassay device with immuno-reference electrode
CN1938589B (zh) * 2004-03-31 2011-12-28 拜尔健康护理有限责任公司 用于实现用于生物传感器的基于阈值的校正函数的方法和装置
KR101503072B1 (ko) 2005-07-20 2015-03-16 바이엘 헬스케어 엘엘씨 게이트형 전류 측정법
CA2986870A1 (en) 2005-09-30 2007-04-12 Ascensia Diabetes Care Holdings Ag Gated voltammetry
RU2455925C2 (ru) * 2006-02-27 2012-07-20 БАЙЕР ХЕЛТКЭА ЭлЭлСи Определение исследуемого вещества с поправкой на температуру для систем биодатчиков
BRPI0711433A2 (pt) * 2006-05-08 2011-11-16 Bayer Healthcare Llc sistema de detecção de saìda anormal para um biosensor
JP4785611B2 (ja) * 2006-05-11 2011-10-05 アークレイ株式会社 血液試料中の特定成分の濃度測定方法および装置
US20080248581A1 (en) * 2007-04-06 2008-10-09 Bayer Healthcare Llc Method for performing correction of blood glucose assay bias using blood hemoglobin concentration
US8000918B2 (en) * 2007-10-23 2011-08-16 Edwards Lifesciences Corporation Monitoring and compensating for temperature-related error in an electrochemical sensor
RU2706691C2 (ru) * 2007-12-10 2019-11-20 Асцензия Диабетс Кэар Холдингс АГ Способ определения концентрации аналита
BRPI0923342A2 (pt) * 2008-12-08 2016-01-12 Bayer Healthcare Llc sistema biosensor com ajuste de sinal
RU2541718C2 (ru) * 2009-06-30 2015-02-20 АРКРЭЙ, Инк. Анализирующее устройство и способ анализа
JP5350960B2 (ja) * 2009-09-30 2013-11-27 アークレイ株式会社 赤血球含有試料における目的成分の測定方法
CA2793878C (en) * 2010-03-22 2018-09-11 Bayer Healthcare Llc Residual compensation for a biosensor
BR112012031166A2 (pt) * 2010-06-07 2018-02-27 Bayer Healthcare Llc compensação baseada eminclinação incluindo sinais de saída secundários
JP5395005B2 (ja) * 2010-07-20 2014-01-22 アークレイ株式会社 糖化タンパク質の測定方法
KR20140063829A (ko) * 2011-09-21 2014-05-27 바이엘 헬쓰케어, 엘엘씨 오차 보상을 갖는 바이오센서

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TW200926203A (en) * 2007-12-04 2009-06-16 Univ Illinois Microcantilever heater-thermometer with integrated temperature-compensated strain sensor
WO2010059687A2 (en) * 2008-11-18 2010-05-27 The United States Of America, As Represented By The Secretary, Department Of Health And Human Services A semiconductor for measuring biological interactions
TW201138743A (en) * 2010-03-12 2011-11-16 Univ Illinois Implantable biomedical devices on bioresorbable substrates
TW201217783A (en) * 2010-09-15 2012-05-01 Mbio Diagnostics Inc System and method for detecting multiple molecules in one assay
TW201305548A (zh) * 2010-10-11 2013-02-01 Mbio Diagnostics Inc 用於細胞分析之系統及方法

Also Published As

Publication number Publication date
US20180209932A1 (en) 2018-07-26
JP6305508B2 (ja) 2018-04-04
JP6698919B2 (ja) 2020-05-27
US20160018355A1 (en) 2016-01-21
TWI636252B (zh) 2018-09-21
JP2018105887A (ja) 2018-07-05
HK1221771A1 (zh) 2017-06-09
EP3276355A1 (en) 2018-01-31
JP2019164166A (ja) 2019-09-26
TW201840977A (zh) 2018-11-16
EP2972396A1 (en) 2016-01-20
TW201443427A (zh) 2014-11-16
IL240815A0 (en) 2015-10-29
CA2902512A1 (en) 2014-10-02
EP3276355B1 (en) 2020-05-06
CN105378484B (zh) 2017-06-09
ES2812806T3 (es) 2021-03-18
JP6539369B2 (ja) 2019-07-03
CN105378484A (zh) 2016-03-02
US9958410B2 (en) 2018-05-01
WO2014159077A1 (en) 2014-10-02
JP2016516191A (ja) 2016-06-02

Similar Documents

Publication Publication Date Title
TWI688768B (zh) 分析物濃度測定的正規化校正
US10646445B2 (en) Analysis compensation including segmented signals converted into signal processing parameters for describing a portion of total error
JP7066649B2 (ja) 分析物濃度決定のシステム誤差補償
JP2016517517A5 (enExample)
JP6949811B2 (ja) 試料分析物濃度の逐次近似
HK40016909A (en) System error compensation of analyte concentration determinations
HK1220769B (en) Progressive approximation of sample analyte concentration
HK1220768B (en) System error compensation of analyte concentration determinations

Legal Events

Date Code Title Description
MM4A Annulment or lapse of patent due to non-payment of fees