JP6305508B2 - 分析物濃度決定の正規化された較正 - Google Patents

分析物濃度決定の正規化された較正 Download PDF

Info

Publication number
JP6305508B2
JP6305508B2 JP2016500871A JP2016500871A JP6305508B2 JP 6305508 B2 JP6305508 B2 JP 6305508B2 JP 2016500871 A JP2016500871 A JP 2016500871A JP 2016500871 A JP2016500871 A JP 2016500871A JP 6305508 B2 JP6305508 B2 JP 6305508B2
Authority
JP
Japan
Prior art keywords
output signal
normalized
analyte
sample
external stimulus
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
JP2016500871A
Other languages
English (en)
Japanese (ja)
Other versions
JP2016516191A5 (enExample
JP2016516191A (ja
Inventor
ウー，ホァン−ピン
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Bayer Healthcare LLC
Original Assignee
Bayer Healthcare LLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bayer Healthcare LLC filed Critical Bayer Healthcare LLC
Publication of JP2016516191A publication Critical patent/JP2016516191A/ja
Publication of JP2016516191A5 publication Critical patent/JP2016516191A5/ja
Application granted granted Critical
Publication of JP6305508B2 publication Critical patent/JP6305508B2/ja
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Images

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N27/00—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
    • G01N27/26—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating electrochemical variables; by using electrolysis or electrophoresis
    • G01N27/28—Electrolytic cell components
    • G01N27/30—Electrodes, e.g. test electrodes; Half-cells
    • G01N27/327—Biochemical electrodes, e.g. electrical or mechanical details for in vitro measurements
    • G01N27/3271—Amperometric enzyme electrodes for analytes in body fluids, e.g. glucose in blood
    • G01N27/3274—Corrective measures, e.g. error detection, compensation for temperature or hematocrit, calibration
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/72—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving blood pigments, e.g. haemoglobin, bilirubin or other porphyrins; involving occult blood
    • G01N33/721—Haemoglobin
    • G01N33/723—Glycosylated haemoglobin
    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
    • G16B5/00—ICT specially adapted for modelling or simulations in systems biology, e.g. gene-regulatory networks, protein interaction networks or metabolic networks

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Hematology (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Molecular Biology (AREA)
  • Physics & Mathematics (AREA)
  • Immunology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biomedical Technology (AREA)
  • Biochemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Pathology (AREA)
  • Urology & Nephrology (AREA)
  • Biotechnology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicinal Chemistry (AREA)
  • Food Science & Technology (AREA)
  • Electrochemistry (AREA)
  • Microbiology (AREA)
  • Cell Biology (AREA)
  • Biophysics (AREA)
  • Theoretical Computer Science (AREA)
  • Spectroscopy & Molecular Physics (AREA)
  • Medical Informatics (AREA)
  • Evolutionary Biology (AREA)
  • Bioinformatics & Computational Biology (AREA)
  • Physiology (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
  • Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
  • Investigating Or Analysing Materials By Optical Means (AREA)
JP2016500871A 2013-03-14 2014-03-07 分析物濃度決定の正規化された較正 Active JP6305508B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201361782520P 2013-03-14 2013-03-14
US61/782,520 2013-03-14
PCT/US2014/021870 WO2014159077A1 (en) 2013-03-14 2014-03-07 Normalized calibration of analyte concentration determinations

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2018039524A Division JP6539369B2 (ja) 2013-03-14 2018-03-06 分析物濃度決定の正規化された較正

Publications (3)

Publication Number Publication Date
JP2016516191A JP2016516191A (ja) 2016-06-02
JP2016516191A5 JP2016516191A5 (enExample) 2017-04-13
JP6305508B2 true JP6305508B2 (ja) 2018-04-04

Family

ID=50439487

Family Applications (3)

Application Number Title Priority Date Filing Date
JP2016500871A Active JP6305508B2 (ja) 2013-03-14 2014-03-07 分析物濃度決定の正規化された較正
JP2018039524A Active JP6539369B2 (ja) 2013-03-14 2018-03-06 分析物濃度決定の正規化された較正
JP2019106913A Active JP6698919B2 (ja) 2013-03-14 2019-06-07 分析物濃度決定の正規化された較正

Family Applications After (2)

Application Number Title Priority Date Filing Date
JP2018039524A Active JP6539369B2 (ja) 2013-03-14 2018-03-06 分析物濃度決定の正規化された較正
JP2019106913A Active JP6698919B2 (ja) 2013-03-14 2019-06-07 分析物濃度決定の正規化された較正

Country Status (10)

Country Link
US (2) US9958410B2 (enExample)
EP (2) EP3276355B1 (enExample)
JP (3) JP6305508B2 (enExample)
CN (1) CN105378484B (enExample)
CA (1) CA2902512A1 (enExample)
ES (1) ES2812806T3 (enExample)
HK (1) HK1221771A1 (enExample)
IL (1) IL240815A0 (enExample)
TW (2) TWI688768B (enExample)
WO (1) WO2014159077A1 (enExample)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN107110786B (zh) * 2014-12-24 2020-10-27 皇家飞利浦有限公司 使用比色传感器进行的测量和校准
HK1248818A1 (zh) * 2015-05-15 2018-10-19 安晟信医疗科技控股公司 改进的生物传感器系统分析物测量
CN109073646A (zh) * 2016-05-13 2018-12-21 荣研化学株式会社 求取待测物在对比物中所占比例的方法、程序、存储介质及装置
CN109690304A (zh) 2016-07-12 2019-04-26 安晟信医疗科技控股公司 通过使用来自两个电极的交替输出信号进行电化学分析的方法
WO2018048488A1 (en) * 2016-09-08 2018-03-15 Hemex Health, Inc. Diagnostics systems and methods
CA3045090A1 (en) 2016-12-05 2018-06-14 Ascensia Diabetes Care Holdings Ag Risk factor monitoring
JP6829158B2 (ja) * 2017-07-18 2021-02-10 株式会社東芝 データ処理装置、データ処理方法、およびプログラム
CA3089212A1 (en) * 2018-01-23 2019-08-01 Dexcom, Inc. Systems, devices, and methods to compensate for temperature effects on sensors
CN120093299A (zh) * 2021-10-12 2025-06-06 深圳硅基传感科技有限公司 分析物浓度的校准方法及分析物传感器
CN120381237A (zh) * 2024-01-27 2025-07-29 深圳硅基传感科技有限公司 用于分析物传感器的灵敏度衰减的校正方法、系统及介质
TWI893839B (zh) * 2024-06-07 2025-08-11 國立臺灣大學 糖化血色素百分比偵測方法以及使用該方法之電子裝置
CN119395106A (zh) * 2024-10-24 2025-02-07 江苏鱼跃凯立特生物科技有限公司 一种测试生物样品中分析物浓度的方法和传感器

Family Cites Families (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6153069A (en) 1995-02-09 2000-11-28 Tall Oak Ventures Apparatus for amperometric Diagnostic analysis
US5620579A (en) 1995-05-05 1997-04-15 Bayer Corporation Apparatus for reduction of bias in amperometric sensors
AU6157898A (en) 1997-02-06 1998-08-26 E. Heller & Company Small volume (in vitro) analyte sensor
TW591230B (en) * 1997-10-14 2004-06-11 Bayer Ag Method for improving the accuracy of the semi-quantitative determination of analyte in fluid samples
US7723099B2 (en) * 2003-09-10 2010-05-25 Abbott Point Of Care Inc. Immunoassay device with immuno-reference electrode
CN1938589B (zh) * 2004-03-31 2011-12-28 拜尔健康护理有限责任公司 用于实现用于生物传感器的基于阈值的校正函数的方法和装置
KR101321296B1 (ko) 2005-07-20 2013-10-28 바이엘 헬스케어 엘엘씨 게이트형 전류 측정법 온도 결정 방법
KR101477947B1 (ko) 2005-09-30 2014-12-30 바이엘 헬스케어 엘엘씨 게이트형 전압 전류 측정 이온화제 및 헤마토크리트 결정 방법
ES2791724T3 (es) * 2006-02-27 2020-11-05 Ascensia Diabetes Care Holdings Ag Medida de analito ajustada en temperatura para sistemas de biosensor
EP2020909A2 (en) * 2006-05-08 2009-02-11 Bayer HealthCare LLC Abnormal output detection system for a biosensor
JP4785611B2 (ja) * 2006-05-11 2011-10-05 アークレイ株式会社 血液試料中の特定成分の濃度測定方法および装置
US20080248581A1 (en) 2007-04-06 2008-10-09 Bayer Healthcare Llc Method for performing correction of blood glucose assay bias using blood hemoglobin concentration
US8000918B2 (en) * 2007-10-23 2011-08-16 Edwards Lifesciences Corporation Monitoring and compensating for temperature-related error in an electrochemical sensor
US7928343B2 (en) * 2007-12-04 2011-04-19 The Board Of Trustees Of The University Of Illinois Microcantilever heater-thermometer with integrated temperature-compensated strain sensor
CN103760356B (zh) * 2007-12-10 2019-06-28 安晟信医疗科技控股公司 斜率式补偿
EP2350644B1 (en) * 2008-11-18 2015-01-07 THE UNITED STATES OF AMERICA as represented by the Secretary, Department of Health and Human Services A semiconductor for measuring biological interactions
JP5738770B2 (ja) * 2008-12-08 2015-06-24 バイエル・ヘルスケア・エルエルシーＢａｙｅｒ ＨｅａｌｔｈＣａｒｅＬＬＣ 信号調整を持つバイオセンサシステム
MX2011013915A (es) * 2009-06-30 2012-05-22 Arkray Inc Dispositivo de analisis y metodo de analisis.
JP5350960B2 (ja) * 2009-09-30 2013-11-27 アークレイ株式会社 赤血球含有試料における目的成分の測定方法
TWI646988B (zh) * 2010-03-12 2019-01-11 美國伊利諾大學理事會 生物醫學裝置及其製造方法、流體遞送監視器、監視在管子中流動之流體的方法、近接感測器及感測兩個物件之間的距離的方法
MX368104B (es) 2010-03-22 2019-09-19 Ascensia Diabetes Care Holdings Ag Compensacion residual para un biosensor.
SG186179A1 (en) 2010-06-07 2013-01-30 Bayer Healthcare Llc Slope-based compensation including secondary output signals
JP5395005B2 (ja) * 2010-07-20 2014-01-22 アークレイ株式会社 糖化タンパク質の測定方法
TW201217783A (en) * 2010-09-15 2012-05-01 Mbio Diagnostics Inc System and method for detecting multiple molecules in one assay
US20120088230A1 (en) * 2010-10-11 2012-04-12 Monique Givens System And Method For Cell Analysis
WO2013043839A1 (en) 2011-09-21 2013-03-28 Bayer Healthcare Llc Biosensor with error compensation

Also Published As

Publication number Publication date
US20160018355A1 (en) 2016-01-21
IL240815A0 (en) 2015-10-29
US9958410B2 (en) 2018-05-01
JP2018105887A (ja) 2018-07-05
TWI688768B (zh) 2020-03-21
ES2812806T3 (es) 2021-03-18
EP3276355A1 (en) 2018-01-31
JP2019164166A (ja) 2019-09-26
TW201443427A (zh) 2014-11-16
US20180209932A1 (en) 2018-07-26
TWI636252B (zh) 2018-09-21
CN105378484A (zh) 2016-03-02
JP6698919B2 (ja) 2020-05-27
JP2016516191A (ja) 2016-06-02
CN105378484B (zh) 2017-06-09
TW201840977A (zh) 2018-11-16
HK1221771A1 (zh) 2017-06-09
EP3276355B1 (en) 2020-05-06
JP6539369B2 (ja) 2019-07-03
EP2972396A1 (en) 2016-01-20
WO2014159077A1 (en) 2014-10-02
CA2902512A1 (en) 2014-10-02

Similar Documents

Publication Publication Date Title
JP6698919B2 (ja) 分析物濃度決定の正規化された較正
JP6494813B2 (ja) 分析物濃度決定のシステム誤差補償
US9164076B2 (en) Slope-based compensation including secondary output signals
CN103003692B (zh) 用于生物传感器的剩余补偿
JP2015155919A (ja) 信号調整を持つバイオセンサシステム
JP2016517517A5 (enExample)
JP6949811B2 (ja) 試料分析物濃度の逐次近似
HK1220769B (en) Progressive approximation of sample analyte concentration
HK1220768B (en) System error compensation of analyte concentration determinations

Legal Events

Date Code Title Description
A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A523

Effective date: 20170306

A621 Written request for application examination

Free format text: JAPANESE INTERMEDIATE CODE: A621

Effective date: 20170306

A977 Report on retrieval

Free format text: JAPANESE INTERMEDIATE CODE: A971007

Effective date: 20171220

TRDD Decision of grant or rejection written
A01 Written decision to grant a patent or to grant a registration (utility model)

Free format text: JAPANESE INTERMEDIATE CODE: A01

Effective date: 20180206

A61 First payment of annual fees (during grant procedure)

Free format text: JAPANESE INTERMEDIATE CODE: A61

Effective date: 20180306

R150 Certificate of patent or registration of utility model

Ref document number: 6305508

Country of ref document: JP

Free format text: JAPANESE INTERMEDIATE CODE: R150

S111 Request for change of ownership or part of ownership

Free format text: JAPANESE INTERMEDIATE CODE: R313113

R350 Written notification of registration of transfer

Free format text: JAPANESE INTERMEDIATE CODE: R350

R250 Receipt of annual fees

Free format text: JAPANESE INTERMEDIATE CODE: R250

R250 Receipt of annual fees

Free format text: JAPANESE INTERMEDIATE CODE: R250

R250 Receipt of annual fees

Free format text: JAPANESE INTERMEDIATE CODE: R250

R250 Receipt of annual fees

Free format text: JAPANESE INTERMEDIATE CODE: R250

R250 Receipt of annual fees

Free format text: JAPANESE INTERMEDIATE CODE: R250

R250 Receipt of annual fees

Free format text: JAPANESE INTERMEDIATE CODE: R250