TWI681760B - Implant device - Google Patents
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- TWI681760B TWI681760B TW107121748A TW107121748A TWI681760B TW I681760 B TWI681760 B TW I681760B TW 107121748 A TW107121748 A TW 107121748A TW 107121748 A TW107121748 A TW 107121748A TW I681760 B TWI681760 B TW I681760B
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Abstract
Description
本發明係關於一種植入材,特別是指一種有助於細胞增生且增進癒合速度之植入材。 The invention relates to an implant, in particular to an implant that helps cell proliferation and improves the healing speed.
植入材的運用非常廣泛,尤其在牙科及骨科的運用領域常見,以下僅以牙科領域之植牙運用為例做說明,亦即以金屬人工植體植入口腔之齒槽骨中,是現行對牙齒缺損的常見醫療行為,在植體植入齒槽骨後,需經過齒槽骨所衍生的骨細胞與植體結合之過程,才能達骨整合(osseointegration)效果;為了供植體結合至齒槽骨,現行在植體表面有以多孔結構為之,以期骨細胞能附著於該多孔結構以與植體結合,但因傳統型孔洞之成型易有大小、深淺、且間隔不一的問題,較不利於齒槽骨初始衍生之骨細胞與植體間的結合作業,亦即初始細胞的規模可能還太小,通常需等細胞成長至大於孔洞尺寸的程度時,細胞才能向外延伸以在該等孔洞間產生鏈結,惟,此一骨整合過程耗費較長時間,致使骨組織的癒合時間較長,仍有待改善。 The use of implants is very extensive, especially in the field of dentistry and orthopedics. The following is only an example of the use of dental implants in the dental field, that is, the use of metal artificial implants in the alveolar bone of the oral cavity is the current For the common medical behaviors of tooth defects, after the implant is implanted into the alveolar bone, the process of combining the bone cells derived from the alveolar bone with the implant is required to achieve the effect of osseointegration; Alveolar bone currently has a porous structure on the surface of the implant, in order to allow bone cells to attach to the porous structure to combine with the implant, but because of the formation of traditional holes, it is easy to have problems of size, depth, and uneven spacing , Which is not conducive to the combination of bone cells derived from the alveolar bone and the implant, that is, the size of the initial cell may be too small. It is usually necessary to wait for the cell to grow larger than the size of the hole before the cell can extend outward. Links are formed between these holes, but this bone integration process takes a long time, resulting in a longer healing time of bone tissue, which still needs to be improved.
因此,本發明之目的,是在提供一種植入材,其可供細胞快速且順利攀附於植體上,以利提升細胞之生長能力,不僅達植體與鎖合處間之穩定結合,且有利縮短鎖合處的組織癒合時間。 Therefore, the object of the present invention is to provide an implant material that allows cells to quickly and smoothly attach to the implant, so as to enhance the growth ability of the cell, not only to achieve a stable combination between the implant and the lock, and Helps shorten the healing time of the tissue at the lock.
於是,本發明植入材,其包含有一具有螺牙部之植體,及分設於該植體兩端之鑽鎖部及鎖合孔;其中,該植體之表面開設有複數孔洞,所述植體之表面至少包括有一在螺牙部的任二相鄰螺牙間向外顯露之桿身表面,該每一孔洞具有一周壁,且該周壁與該植體之表面相接的邊緣處形成有一端緣,該等相鄰孔洞之端緣連接以使相鄰周壁相連,因而該等相鄰孔洞接連相通以建構出一通道,而該等孔洞之連通係可形成多條串接型態,以便形成複數條通道;據上,在植入材植入一鎖合處後,由該鎖合處所衍生之細胞可輕易附著於該等孔洞之端緣處,並伸入該等孔洞之每一通道內進行快速攀附並增生,增生後之細胞更由該等孔洞、通道向外延伸並持續附著於其他孔洞及通道,如此以形成細胞相互鏈結作用,因而細胞可在短時間內穩定攀附於植體上,以達將植體予以包覆、定位之效果,故大幅提升植體與鎖合處間之結合效果,不僅避免癒合過程產生植體鬆動,更有利縮短鎖合處的組織的癒合時間。 Therefore, the implant of the present invention includes an implant with screw teeth, and drill locks and locking holes at two ends of the implant; wherein, a plurality of holes are formed on the surface of the implant. The surface of the implant includes at least a shaft surface that is exposed outwardly between any two adjacent teeth of the screw portion, each hole has a peripheral wall, and the peripheral wall contacts the edge of the surface of the implant An end edge is formed, and the end edges of the adjacent holes are connected to connect the adjacent peripheral walls, so that the adjacent holes communicate with each other to construct a channel, and the connection of the holes can form a plurality of series connection patterns In order to form a plurality of channels; according to the above, after the implant is implanted in a lock, the cells derived from the lock can be easily attached to the edges of the holes and extend into each of the holes Quickly attach and proliferate in a channel, and the proliferated cells extend outward from the holes and channels and continue to attach to other holes and channels, so as to form a mutual linking effect of the cells, so the cells can stably attach in a short time On the implant, the effect of covering and positioning the implant is achieved, so the combination effect between the implant and the lock is greatly improved, which not only avoids the loosening of the implant during the healing process, but also helps shorten the tissue of the lock. Healing time.
〔本發明〕 〔this invention〕
3‧‧‧植入材 3‧‧‧Implant
31‧‧‧植體 31‧‧‧Implant
32‧‧‧孔洞 32‧‧‧hole
311‧‧‧鑽鎖部 311‧‧‧Drill lock
312‧‧‧鎖合孔 312‧‧‧lock hole
313‧‧‧螺牙部 313‧‧‧Thread
3131、3132‧‧‧螺牙段 3131, 3132
321‧‧‧周壁 321‧‧‧ Zhoubi
322‧‧‧端緣 322‧‧‧End edge
323‧‧‧通道 323‧‧‧channel
E1‧‧‧第一端 E1‧‧‧The first end
E2‧‧‧第二端 E2‧‧‧Second end
P1、P2‧‧‧螺牙牙距 P1, P2‧‧‧Pitch
OD1‧‧‧第一端的最大外徑 OD1‧‧‧Maximum outer diameter of the first end
OD2‧‧‧第二端的最大外徑 OD2‧‧‧Maximum outer diameter of the second end
5‧‧‧齒槽骨 5‧‧‧Alveolar bone
51‧‧‧預鑽孔 51‧‧‧Pre-drilled
BC‧‧‧細胞 BC‧‧‧cell
S‧‧‧植體之表面 S‧‧‧Implant surface
S1‧‧‧桿身表面 S1‧‧‧Shaft surface
S2‧‧‧螺牙表面 S2‧‧‧Screw surface
圖1 是本發明第一較佳實施例之示意圖。 FIG. 1 is a schematic diagram of the first preferred embodiment of the present invention.
圖2 是本發明第二較佳實施例之示意圖。 2 is a schematic diagram of the second preferred embodiment of the present invention.
圖3 是本發明第三較佳實施例之示意圖。 FIG. 3 is a schematic diagram of the third preferred embodiment of the present invention.
圖4A至圖4H 是本發明之植體孔洞分佈的不同實施示意圖,其中,圖4A、4B是圖1圈圍處的放大示意圖,圖4C、4D、4G是圖2圈圍處的放大示意圖,圖4E、4F、4H是圖3圈圍處的放大示意圖。 FIGS. 4A to 4H are schematic diagrams of different implementations of the distribution of implant holes of the present invention, wherein FIGS. 4A and 4B are enlarged schematic diagrams of the circled area of FIG. 1, and FIGS. 4C, 4D and 4G are enlarged schematic diagrams of the circled area of FIG. 2, 4E, 4F, and 4H are enlarged schematic views of the circle around FIG. 3.
圖5A至圖5C 是本發明之植體孔洞連接以形成呈不同連通型態之通道的平面放大示意圖。 FIG. 5A to FIG. 5C are enlarged plan views of the connection of the implant holes of the present invention to form channels with different communication types.
圖6 是圖5A之立體示意圖。 FIG. 6 is a perspective schematic view of FIG. 5A.
圖7至圖9 是本發明運用至牙科植牙手術的使用示意圖。 7 to 9 are schematic diagrams of the present invention applied to dental implant surgery.
有關本發明前述及其他技術內容、特點與功效,在以下配合參考圖式之較佳實施例的詳細說明中,將可清楚明白。 The foregoing and other technical contents, features and effects of the present invention will be clearly understood in the following detailed description of preferred embodiments with reference to the drawings.
本發明較佳實施例之植入材3,主要用於醫療植入方面,如運用在牙科、骨科等需有細胞增生的鎖合處,亦即該植入材3可作為植入至口腔內齒槽骨之人工植牙體,或作為骨科手術所使用之植入體如人工骨釘等,而以下僅以該鎖合處是口腔內之齒槽骨,而該植入材3作為植入齒槽骨之植牙體為例說明。
The
參閱圖1,本發明之植入材3包含有一植體31,一鑽鎖部311,及一相反該鑽鎖部311處之鎖合孔312;其中,該植體31具有第一端E1及一相對於該第一端E1之第二端E2,而該鑽鎖部311設於該第一端E1處,該鎖合孔312形成於該植體31的第二端E2且相反該鑽鎖部311處,該植體31上位於兩端E1,E2之間螺旋設有一螺牙部313,該螺牙部313可包括一自該第一端E1延伸至第二端E2處之螺牙段3131,該螺牙段3131之任二相鄰螺牙間形成一牙距P1,以形成一段式螺牙結構(參圖1);或者該螺牙部313包括有至少二螺牙段3131、3132(參圖2、3),在此僅以設兩螺牙段為例說明,即植體31上螺旋設有自植體31的第一端E1延伸之螺牙段3131,以及從該螺牙段3131延伸至該第二端
E2間之另一螺牙段3132,該螺牙段3131之任二相鄰螺牙間形成一牙距P1,該另一螺牙段3132之任二相鄰螺牙間形成一牙距P2,前述螺牙牙距P1、P2可為不同,如螺牙段3131之牙距P1較佳係大於另一螺牙段3132之牙距P2,同時該第二端E2之最大外徑OD2可等於第一端E1之最大外徑OD1(參圖3),或該第二端E2之最大外徑OD2可大於第一端E1之最大外徑OD1(參圖2),例如該另一螺牙段3132所在之植體31的外徑朝該第二端E2逐漸變大,以便該另一螺牙段3132的螺牙外徑亦朝相反該鑽鎖部311方向逐漸增加,有利快速且穩固鎖設之效果。
Referring to FIG. 1, the
再者,該植體31之表面S開設複數孔洞32,該等孔洞32之孔徑大小及形狀並不限制,所述表面S係包括植體31上可顯露於外的任何表面,例如,該植體31之表面S包括一桿身表面S1,所述桿身表面S1是由該第一端E1軸向延伸至第二端E2並顯露於外之外表面,且該外表面更係可在該螺牙部313的任二相鄰螺牙間顯露而出,或者該植體31之表面S可包括前述桿身表面S1及該螺牙部313的全部或局部螺牙之螺牙表面S2,以便該植體31顯露於外之局部區域或全部區域開設有該等孔洞32:以圖1之一段螺牙結構為例,可在延伸於第一端E1至第二端E2間並於螺牙段3131之相鄰螺牙間所露出的桿身表面S1開設孔洞32(如圖4A所示),或者在前述桿身表面S1、前述螺牙段3131的螺牙之任何螺牙表面S2(如上、下牙面或兩牙面等),均開設有孔洞32,呈如圖4B所示。
Furthermore, the surface S of the
若以圖2、圖3之二段螺牙結構為例,可如圖4G、圖4H所示在延伸於第一端E1至第二端E2間並於兩螺牙段
3131、3132之任二相鄰螺牙間所露出的桿身表面S1開設孔洞32;或如圖4C、圖4E所示在前述桿身表面S1及其一螺牙段3131的螺牙之任何螺牙表面S2開設孔洞32;或如圖4D、圖4F所示在前述桿身表面S1、螺牙段3131與另一螺牙段3132的螺牙之任何螺牙表面S2(如上、下牙面或兩牙面等),均開設有孔洞32。
If the two-stage screw structure of FIGS. 2 and 3 is taken as an example, it can extend between the first end E1 and the second end E2 and between the two screw sections as shown in FIGS. 4G and
配合參閱圖6,該每一孔洞32具有一周壁321,該周壁321係從該植體31之表面S朝該植體31內部延伸的壁面以圈圍形成該孔洞32,且該周壁321的壁面較佳可呈粗糙非光滑態樣,該周壁321與該植體31之表面S相接於一端緣322,任一孔洞32之端緣322與另一相鄰孔洞32之端緣322相接以使相鄰之周壁321彼此連接,因而該等相鄰孔洞32一個接著一個呈連通而形成一通道323,該植體31利用該等孔洞32之連通形成有複數條通道323,其連通態樣可呈圖5A至5C態樣(說明如後),在此僅將圖5A以立體圖面呈如圖6所示,同時前述圖4A-4H之孔洞32亦僅以圖5A態樣為例來呈現;再者,該每一孔洞32之端緣322較佳可呈非平整狀,例如該周壁321與該植體31之表面S呈相接之邊緣處形成凹凸交錯的非平滑線條,使該端緣322呈粗糙態樣,以下使用描述以該端緣322呈粗糙狀為例來說明。
Referring to FIG. 6, each
承接前段,該等孔洞32之連接方式影響每一通道323之連通方向,例如:該等孔洞32環繞著該植體31之表面S(如朝圖中所示X方向)呈連接成串,以便該植體31內形成有複數條獨立之橫向通道323,如圖5A及圖6所示呈橫向連通空間;該等孔洞32亦可朝如圖中所示Y方向(如呈軸向)連接,以形成複數條獨立縱向之通道323,如圖5B所示呈縱向連通空間;該等孔洞
32亦可朝X、Y方向連接,使該等相鄰的獨立通道323彼此連通,因而形成縱橫交錯之貫通型態,如圖5C所示呈縱、橫向連通空間;前述各連通配置可供細胞於攀附、增生過程形成均勻且規則分佈,進而相互鏈結以將植體31穩固包覆而使植體31定位,以下描述僅以圖5A態樣來說明。
Following the previous stage, the connection of the
參閱圖7,使用時,係將該植入材3運用於植入口腔之齒槽骨5中的植牙手術為例;進行植牙手術時,先以手術器具(圖中未示)插掣該鎖合孔312中,以連動該螺牙部313針對齒槽骨5之預鑽孔51的壁面進行切削攻入,以達植入定位;若植體31是具有兩螺牙段3131、3132時(參圖8),在鑽鎖過程中可利用具較大牙距P1之螺牙段3131先與該壁面呈大面積接觸,以切削壁面並螺入該預鑽孔51中,再由具較小牙距P2之另一螺牙段3132沿著該螺牙段3131之螺旋軌跡繼續切削螺入,如此可讓該植體31快速螺入齒槽骨5中,以助減少患者在手術過程中的不適感,亦可達植入穩固定位。
Referring to FIG. 7, when using, the
當該植體31植入齒槽骨5後,齒槽骨5在癒合過程中會衍生出骨細胞BC(參圖9僅簡意示出),因該等孔洞32之端緣322呈粗糙狀,故可供骨細胞BC快速且順利抓附於該等端緣322並伸入該等孔洞32內,再於該等孔洞32內、外進行攀附及增生行為,換言之,該等骨細胞BC沿著該等端緣322以進入該等孔洞32並著床後,即可在該等通道323中的周壁321上快速附著並執行增殖、分化的細胞增生行為,經由每一通道323之內部連通空間,可供增生之骨細胞BC沿著周壁321持續攀附、延伸以蔓延於每一通道323中,再從各自通道323、孔洞32伸出並沿著表面S
以攀附至其他的通道323、孔洞32之中,進而該等骨細胞BC可彼此緊密鏈結,並包覆整個植體31,使該植體31穩固定位於齒槽骨5中而避免鬆動,故增加植體31與齒槽骨5間之骨整合效果。
After the
因此,利用該等相互連接之孔洞32,或者該等孔洞32適時搭配粗糙狀端緣322的配置,該等骨細胞BC可順利且快速附著於該等端緣322及孔洞32,以提升細胞BC之初始攀附及生長能力,並供細胞BC在該等通道323內持續攀附並快速均勻分佈,加上該等通道323的內部連通空間也讓植體31與骨細胞BC之間呈大接觸面積,更有利提升細胞之附著及生長能力,因而促使骨細胞BC產生快速攀附、增生行為及緊密鏈結作用,不僅增加植牙後之骨整合效果,更加快骨骼組織的癒合速度,以縮短癒合時間。
Therefore, by using the
歸納前述,本發明植入材,主要利用該植體之表面開設複數孔洞,且該等相鄰孔洞之端緣的接續連接成串,以利多條串接形成複數條通道,藉此,植體所植入的鎖合處所衍生之細胞順利附著於該等孔洞,並伸入每一通道中快速攀附、分佈並增生,增生後細胞更在該等孔洞、通道之間相互鏈結,以便細胞在短時間內攀附於植體上並包覆植體呈穩固定位,進而提升植體與鎖合處之結合效果,不僅避免植體產生鬆動,更加快鎖合處的癒合速度。 In summary, the implant of the present invention mainly uses the surface of the implant to create a plurality of holes, and the end edges of the adjacent holes are connected in series to facilitate the formation of a plurality of channels by multiple series connection, thereby, the implant The cells derived from the implanted locking site are smoothly attached to the holes, and extend into each channel to quickly climb, distribute and proliferate. After proliferation, the cells are further linked between the holes and channels so that the cells are in Climbing on the implant in a short time and covering the implant in a stable position, thereby improving the combination effect of the implant and the lock, not only to avoid loosening of the implant, but also to speed up the healing of the lock.
惟以上所述者,僅為說明本發明之較佳實施例而已,當不能以此限定本發明實施之範圍,即大凡依本發明申請專利範圍及發明說明書內容所作之簡單的等效變化與修飾,皆應仍屬本發明專利涵蓋之範圍內。 However, the above are only for explaining the preferred embodiments of the present invention, but the scope of the implementation of the present invention cannot be limited by this, that is, simple equivalent changes and modifications made according to the scope of the patent application of the present invention and the content of the description of the invention , Should still fall within the scope of this invention patent.
32‧‧‧孔洞 32‧‧‧hole
321‧‧‧周壁 321‧‧‧ Zhoubi
322‧‧‧端緣 322‧‧‧End edge
323‧‧‧通道 323‧‧‧channel
S‧‧‧植體之表面 S‧‧‧Implant surface
Claims (7)
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TW107121748A TWI681760B (en) | 2018-06-25 | 2018-06-25 | Implant device |
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Citations (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5716412A (en) * | 1996-09-30 | 1998-02-10 | Johnson & Johnson Professional, Inc. | Implantable article with ablated surface |
CN101889911A (en) * | 2009-05-19 | 2010-11-24 | 爱尔兰国立大学,戈尔韦 | The bone implant that has surface anchoring structure |
US20160015483A1 (en) * | 2014-04-30 | 2016-01-21 | Osseodyne Surgical Solutions, LLC. | Osseointegrative surgical implant |
TWM538786U (en) * | 2016-10-28 | 2017-04-01 | Taiwan Shan Yin International Co Ltd | Dental implant |
-
2018
- 2018-06-25 TW TW107121748A patent/TWI681760B/en active
Patent Citations (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5716412A (en) * | 1996-09-30 | 1998-02-10 | Johnson & Johnson Professional, Inc. | Implantable article with ablated surface |
CN101889911A (en) * | 2009-05-19 | 2010-11-24 | 爱尔兰国立大学,戈尔韦 | The bone implant that has surface anchoring structure |
US20160015483A1 (en) * | 2014-04-30 | 2016-01-21 | Osseodyne Surgical Solutions, LLC. | Osseointegrative surgical implant |
TWM538786U (en) * | 2016-10-28 | 2017-04-01 | Taiwan Shan Yin International Co Ltd | Dental implant |
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