TWI440477B - 兩相微泡組合物用於製備治療具人類乳突病毒狀態之低度鱗狀上皮內病變之藥物的用途 - Google Patents
兩相微泡組合物用於製備治療具人類乳突病毒狀態之低度鱗狀上皮內病變之藥物的用途 Download PDFInfo
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- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/20—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing sulfur, e.g. dimethyl sulfoxide [DMSO], docusate, sodium lauryl sulfate or aminosulfonic acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/107—Emulsions ; Emulsion preconcentrates; Micelles
- A61K9/1075—Microemulsions or submicron emulsions; Preconcentrates or solids thereof; Micelles, e.g. made of phospholipids or block copolymers
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- Chemical Kinetics & Catalysis (AREA)
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- Virology (AREA)
- Endocrinology (AREA)
- Medicinal Preparation (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Oil, Petroleum & Natural Gas (AREA)
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| FR3008900B1 (fr) * | 2013-07-25 | 2018-03-30 | Centre Nat Rech Scient | Nanoparticules lipidiques multicompartimentees |
| US8986732B2 (en) * | 2013-08-12 | 2015-03-24 | Helix Biopharma Corporation | Biphasic lipid-vesicle compositions and methods for treating cervical dysplasia by intravaginal delivery |
| US10159646B2 (en) | 2013-08-12 | 2018-12-25 | Altum-Avro Pharma Partnership | Biphasic lipid-vesicle compositions and methods for treating cervical dysplasia by intravaginal delivery |
| WO2015034925A1 (en) | 2013-09-03 | 2015-03-12 | Moderna Therapeutics, Inc. | Circular polynucleotides |
| US20150147382A1 (en) * | 2013-09-23 | 2015-05-28 | Exir Nano Sina Company | Topical liposomal compositions for delivering hydrophobic drugs and methods preparing same |
| EP4253544A3 (en) | 2017-05-18 | 2023-12-20 | ModernaTX, Inc. | Modified messenger rna comprising functional rna elements |
| CA3064782A1 (en) * | 2017-05-26 | 2018-11-29 | Altum Pharmaceuticals Inc. | Biphasix cannabinoid delivery |
| US11939601B2 (en) | 2017-11-22 | 2024-03-26 | Modernatx, Inc. | Polynucleotides encoding phenylalanine hydroxylase for the treatment of phenylketonuria |
| EP3714048B1 (en) | 2017-11-22 | 2025-04-09 | ModernaTX, Inc. | Polynucleotides encoding ornithine transcarbamylase for the treatment of urea cycle disorders |
| JP2022500436A (ja) | 2018-09-13 | 2022-01-04 | モダーナティエックス・インコーポレイテッドModernaTX, Inc. | 糖原病を処置するためのグルコース−６−ホスファターゼをコードするポリヌクレオチド |
| MA53615A (fr) | 2018-09-14 | 2021-07-21 | Modernatx Inc | Polynucléotides codant pour le polypeptide a1, de la famille de l'uridine diphosphate glycosyltransférase 1, pour le traitement du syndrome de crigler-najjar |
| BR112022005354A2 (pt) * | 2019-09-23 | 2022-08-23 | Dds Res Inc | Composições de vesícula lipídica com agentes potencializadores de penetração |
| US20240207374A1 (en) | 2021-03-24 | 2024-06-27 | Modernatx, Inc. | Lipid nanoparticles containing polynucleotides encoding glucose-6-phosphatase and uses thereof |
| WO2022204390A1 (en) | 2021-03-24 | 2022-09-29 | Modernatx, Inc. | Lipid nanoparticles containing polynucleotides encoding phenylalanine hydroxylase and uses thereof |
| CA3213099A1 (en) | 2021-03-24 | 2022-09-29 | Robert A. Love | Peptides and methods for reducing skin pigmentation |
| WO2022204380A1 (en) | 2021-03-24 | 2022-09-29 | Modernatx, Inc. | Lipid nanoparticles containing polynucleotides encoding propionyl-coa carboxylase alpha and beta subunits and uses thereof |
| US20240376445A1 (en) | 2021-06-22 | 2024-11-14 | Modernatx, Inc. | Polynucleotides encoding uridine diphosphate glycosyltransferase 1 family, polypeptide a1 for the treatment of crigler-najjar syndrome |
| WO2023081259A2 (en) * | 2021-11-04 | 2023-05-11 | Glo Pharma, Inc. | Methods and compositions for cosmetic applications |
| EP4562163A1 (en) | 2022-07-26 | 2025-06-04 | ModernaTX, Inc. | Engineered polynucleotides for temporal control of expression |
| WO2024130158A1 (en) | 2022-12-16 | 2024-06-20 | Modernatx, Inc. | Lipid nanoparticles and polynucleotides encoding extended serum half-life interleukin-22 for the treatment of metabolic disease |
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| DK0711148T3 (da) * | 1993-07-28 | 2001-01-02 | Pharmaderm Lab Ltd | Dobbeltfasede multilamellære lipidblærer |
| IN184589B (enExample) * | 1996-10-16 | 2000-09-09 | Alza Corp | |
| US5993852A (en) | 1997-08-29 | 1999-11-30 | Pharmaderm Laboratories Ltd. | Biphasic lipid vesicle composition for transdermal administration of an immunogen |
| US6656499B1 (en) * | 1999-11-12 | 2003-12-02 | Pharmaderm Laboratories, Ltd. | Composition for transdermal and dermal administration of interferon-α |
| TWI272948B (en) | 2003-05-01 | 2007-02-11 | Ares Trading Sa | HSA-free stabilized interferon liquid formulations |
| EP1576952A1 (en) | 2004-03-18 | 2005-09-21 | OctoPlus Technologies B.V. | Hydrogel microspheres with improved release profile |
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2008
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2017
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Also Published As
| Publication number | Publication date |
|---|---|
| US8945529B2 (en) | 2015-02-03 |
| HUE033256T2 (hu) | 2017-11-28 |
| JP5587762B2 (ja) | 2014-09-10 |
| EP2134353A4 (en) | 2013-08-07 |
| AU2008234364A1 (en) | 2008-10-09 |
| CA2681565C (en) | 2016-10-25 |
| TW200846030A (en) | 2008-12-01 |
| EP2134353A1 (en) | 2009-12-23 |
| DK2134353T3 (en) | 2017-02-20 |
| JP2010522698A (ja) | 2010-07-08 |
| CY1118794T1 (el) | 2017-07-12 |
| LT2134353T (lt) | 2017-03-27 |
| US20130216610A1 (en) | 2013-08-22 |
| US20100196453A1 (en) | 2010-08-05 |
| EP2134353B1 (en) | 2016-11-16 |
| AU2008234364B2 (en) | 2013-10-17 |
| MX2009010405A (es) | 2010-02-03 |
| CA2681565A1 (en) | 2008-10-09 |
| HRP20170250T1 (hr) | 2017-04-07 |
| US20130224283A1 (en) | 2013-08-29 |
| PL2134353T3 (pl) | 2017-06-30 |
| ES2617063T3 (es) | 2017-06-15 |
| SI2134353T1 (sl) | 2017-03-31 |
| WO2008119160A1 (en) | 2008-10-09 |
| PT2134353T (pt) | 2017-02-15 |
| KR20090130081A (ko) | 2009-12-17 |
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