TWI440477B - 兩相微泡組合物用於製備治療具人類乳突病毒狀態之低度鱗狀上皮內病變之藥物的用途 - Google Patents
兩相微泡組合物用於製備治療具人類乳突病毒狀態之低度鱗狀上皮內病變之藥物的用途 Download PDFInfo
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- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/20—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing sulfur, e.g. dimethyl sulfoxide [DMSO], docusate, sodium lauryl sulfate or aminosulfonic acids
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/107—Emulsions ; Emulsion preconcentrates; Micelles
- A61K9/1075—Microemulsions or submicron emulsions; Preconcentrates or solids thereof; Micelles, e.g. made of phospholipids or block copolymers
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- Virology (AREA)
- Medicinal Preparation (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Oil, Petroleum & Natural Gas (AREA)
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| FR3008900B1 (fr) * | 2013-07-25 | 2018-03-30 | Centre Nat Rech Scient | Nanoparticules lipidiques multicompartimentees |
| US8986732B2 (en) * | 2013-08-12 | 2015-03-24 | Helix Biopharma Corporation | Biphasic lipid-vesicle compositions and methods for treating cervical dysplasia by intravaginal delivery |
| US10159646B2 (en) * | 2013-08-12 | 2018-12-25 | Altum-Avro Pharma Partnership | Biphasic lipid-vesicle compositions and methods for treating cervical dysplasia by intravaginal delivery |
| EP3041938A1 (en) | 2013-09-03 | 2016-07-13 | Moderna Therapeutics, Inc. | Circular polynucleotides |
| US20150147382A1 (en) * | 2013-09-23 | 2015-05-28 | Exir Nano Sina Company | Topical liposomal compositions for delivering hydrophobic drugs and methods preparing same |
| US11485972B2 (en) | 2017-05-18 | 2022-11-01 | Modernatx, Inc. | Modified messenger RNA comprising functional RNA elements |
| CN111093633A (zh) * | 2017-05-26 | 2020-05-01 | 奥特姆医药公司 | 双相大麻素递送 |
| US11939601B2 (en) | 2017-11-22 | 2024-03-26 | Modernatx, Inc. | Polynucleotides encoding phenylalanine hydroxylase for the treatment of phenylketonuria |
| JP7423522B2 (ja) | 2017-11-22 | 2024-01-29 | モダーナティエックス・インコーポレイテッド | 尿素サイクル異常症の治療のためのオルニチントランスカルバミラーゼをコードするポリヌクレオチド |
| MX2021003015A (es) | 2018-09-13 | 2021-07-15 | Modernatx Inc | Polinucleotidos que codifican glucosa-6-fosfatasa para el tratamiento de la glucogenosis. |
| AU2019339430A1 (en) | 2018-09-14 | 2021-04-29 | Modernatx, Inc. | Polynucleotides encoding uridine diphosphate glycosyltransferase 1 family, polypeptide A1 for the treatment of Crigler-Najjar Syndrome |
| MX2022003446A (es) * | 2019-09-23 | 2022-07-13 | Dds Res Inc | Composiciones de vesiculas lipidicas con agentes potenciadores de la penetracion. |
| WO2022204371A1 (en) | 2021-03-24 | 2022-09-29 | Modernatx, Inc. | Lipid nanoparticles containing polynucleotides encoding glucose-6-phosphatase and uses thereof |
| KR20240035939A (ko) | 2021-03-24 | 2024-03-19 | 글로 파마, 인크. | 피부 색소침착을 감소시키기 위한 펩타이드 및 방법 |
| US20240216288A1 (en) | 2021-03-24 | 2024-07-04 | Modernatx, Inc. | Lipid nanoparticles containing polynucleotides encoding propionyl-coa carboxylase alpha and beta subunits and uses thereof |
| WO2022204390A1 (en) | 2021-03-24 | 2022-09-29 | Modernatx, Inc. | Lipid nanoparticles containing polynucleotides encoding phenylalanine hydroxylase and uses thereof |
| US20240376445A1 (en) | 2021-06-22 | 2024-11-14 | Modernatx, Inc. | Polynucleotides encoding uridine diphosphate glycosyltransferase 1 family, polypeptide a1 for the treatment of crigler-najjar syndrome |
| WO2023081259A2 (en) * | 2021-11-04 | 2023-05-11 | Glo Pharma, Inc. | Methods and compositions for cosmetic applications |
| MA71619A (fr) | 2022-07-26 | 2025-05-30 | Modernatx, Inc. | Polynucléotides modifiés pour la régulation temporelle de l'expression |
| WO2024130158A1 (en) | 2022-12-16 | 2024-06-20 | Modernatx, Inc. | Lipid nanoparticles and polynucleotides encoding extended serum half-life interleukin-22 for the treatment of metabolic disease |
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| US5358708A (en) | 1993-01-29 | 1994-10-25 | Schering Corporation | Stabilization of protein formulations |
| ATE195866T1 (de) * | 1993-07-28 | 2000-09-15 | Pharmaderm Lab Ltd | Zweiphasige multilamellare lipidvesikel |
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| TWI272948B (en) | 2003-05-01 | 2007-02-11 | Ares Trading Sa | HSA-free stabilized interferon liquid formulations |
| EP1576952A1 (en) * | 2004-03-18 | 2005-09-21 | OctoPlus Technologies B.V. | Hydrogel microspheres with improved release profile |
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Also Published As
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| EP2134353B1 (en) | 2016-11-16 |
| HRP20170250T1 (hr) | 2017-04-07 |
| CA2681565C (en) | 2016-10-25 |
| JP2010522698A (ja) | 2010-07-08 |
| CA2681565A1 (en) | 2008-10-09 |
| WO2008119160A1 (en) | 2008-10-09 |
| SI2134353T1 (sl) | 2017-03-31 |
| PT2134353T (pt) | 2017-02-15 |
| US20130216610A1 (en) | 2013-08-22 |
| MX2009010405A (es) | 2010-02-03 |
| LT2134353T (lt) | 2017-03-27 |
| JP5587762B2 (ja) | 2014-09-10 |
| US20100196453A1 (en) | 2010-08-05 |
| US8945529B2 (en) | 2015-02-03 |
| ES2617063T3 (es) | 2017-06-15 |
| DK2134353T3 (en) | 2017-02-20 |
| AU2008234364A1 (en) | 2008-10-09 |
| AU2008234364B2 (en) | 2013-10-17 |
| KR20090130081A (ko) | 2009-12-17 |
| US20130224283A1 (en) | 2013-08-29 |
| EP2134353A1 (en) | 2009-12-23 |
| HUE033256T2 (hu) | 2017-11-28 |
| CY1118794T1 (el) | 2017-07-12 |
| TW200846030A (en) | 2008-12-01 |
| EP2134353A4 (en) | 2013-08-07 |
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