TWI367113B - Random and non-random alkylene oxide polymer alloy compositions - Google Patents

Random and non-random alkylene oxide polymer alloy compositions

Info

Publication number
TWI367113B
TWI367113B TW093103318A TW93103318A TWI367113B TW I367113 B TWI367113 B TW I367113B TW 093103318 A TW093103318 A TW 093103318A TW 93103318 A TW93103318 A TW 93103318A TW I367113 B TWI367113 B TW I367113B
Authority
TW
Taiwan
Prior art keywords
random
alkylene oxide
polymer alloy
alloy compositions
oxide polymer
Prior art date
Application number
TW093103318A
Other languages
English (en)
Other versions
TW200507888A (en
Inventor
Tadeusz Z Wellisz
Timothy C Fisher
Jonathan K Armstrong
John Cambridge
Original Assignee
Syncera Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Syncera Inc filed Critical Syncera Inc
Publication of TW200507888A publication Critical patent/TW200507888A/zh
Application granted granted Critical
Publication of TWI367113B publication Critical patent/TWI367113B/zh

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/14—Macromolecular materials
    • A61L27/18—Macromolecular materials obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/74—Synthetic polymeric materials
    • A61K31/765—Polymers containing oxygen
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0014—Skin, i.e. galenical aspects of topical compositions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L24/00—Surgical adhesives or cements; Adhesives for colostomy devices
    • A61L24/0047—Composite materials, i.e. containing one material dispersed in a matrix of the same or different material
    • A61L24/0073—Composite materials, i.e. containing one material dispersed in a matrix of the same or different material with a macromolecular matrix
    • A61L24/0084—Composite materials, i.e. containing one material dispersed in a matrix of the same or different material with a macromolecular matrix containing fillers of phosphorus-containing inorganic compounds, e.g. apatite
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L24/00—Surgical adhesives or cements; Adhesives for colostomy devices
    • A61L24/0047—Composite materials, i.e. containing one material dispersed in a matrix of the same or different material
    • A61L24/0073—Composite materials, i.e. containing one material dispersed in a matrix of the same or different material with a macromolecular matrix
    • A61L24/0094—Composite materials, i.e. containing one material dispersed in a matrix of the same or different material with a macromolecular matrix containing macromolecular fillers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L24/00—Surgical adhesives or cements; Adhesives for colostomy devices
    • A61L24/04—Surgical adhesives or cements; Adhesives for colostomy devices containing macromolecular materials
    • A61L24/046—Surgical adhesives or cements; Adhesives for colostomy devices containing macromolecular materials obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/14—Macromolecular materials
    • A61L27/26—Mixtures of macromolecular compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/40—Composite materials, i.e. containing one material dispersed in a matrix of the same or different material
    • A61L27/44—Composite materials, i.e. containing one material dispersed in a matrix of the same or different material having a macromolecular matrix
    • A61L27/46—Composite materials, i.e. containing one material dispersed in a matrix of the same or different material having a macromolecular matrix with phosphorus-containing inorganic fillers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/40—Composite materials, i.e. containing one material dispersed in a matrix of the same or different material
    • A61L27/44—Composite materials, i.e. containing one material dispersed in a matrix of the same or different material having a macromolecular matrix
    • A61L27/48—Composite materials, i.e. containing one material dispersed in a matrix of the same or different material having a macromolecular matrix with macromolecular fillers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08L—COMPOSITIONS OF MACROMOLECULAR COMPOUNDS
    • C08L53/00—Compositions of block copolymers containing at least one sequence of a polymer obtained by reactions only involving carbon-to-carbon unsaturated bonds; Compositions of derivatives of such polymers
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08L—COMPOSITIONS OF MACROMOLECULAR COMPOUNDS
    • C08L71/00—Compositions of polyethers obtained by reactions forming an ether link in the main chain; Compositions of derivatives of such polymers
    • C08L71/02—Polyalkylene oxides
    • C—CHEMISTRY; METALLURGY
    • C09—DYES; PAINTS; POLISHES; NATURAL RESINS; ADHESIVES; COMPOSITIONS NOT OTHERWISE PROVIDED FOR; APPLICATIONS OF MATERIALS NOT OTHERWISE PROVIDED FOR
    • C09J—ADHESIVES; NON-MECHANICAL ASPECTS OF ADHESIVE PROCESSES IN GENERAL; ADHESIVE PROCESSES NOT PROVIDED FOR ELSEWHERE; USE OF MATERIALS AS ADHESIVES
    • C09J153/00—Adhesives based on block copolymers containing at least one sequence of a polymer obtained by reactions only involving carbon-to-carbon unsaturated bonds; Adhesives based on derivatives of such polymers
    • C—CHEMISTRY; METALLURGY
    • C11—ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
    • C11D—DETERGENT COMPOSITIONS; USE OF SINGLE SUBSTANCES AS DETERGENTS; SOAP OR SOAP-MAKING; RESIN SOAPS; RECOVERY OF GLYCEROL
    • C11D3/00—Other compounding ingredients of detergent compositions covered in group C11D1/00
    • C11D3/16—Organic compounds
    • C11D3/37—Polymers
    • C11D3/3703—Macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds
    • C11D3/3707—Polyethers, e.g. polyalkyleneoxides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08L—COMPOSITIONS OF MACROMOLECULAR COMPOUNDS
    • C08L2666/00—Composition of polymers characterized by a further compound in the blend, being organic macromolecular compounds, natural resins, waxes or and bituminous materials, non-macromolecular organic substances, inorganic substances or characterized by their function in the composition
    • C08L2666/02—Organic macromolecular compounds, natural resins, waxes or and bituminous materials
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08L—COMPOSITIONS OF MACROMOLECULAR COMPOUNDS
    • C08L2666/00—Composition of polymers characterized by a further compound in the blend, being organic macromolecular compounds, natural resins, waxes or and bituminous materials, non-macromolecular organic substances, inorganic substances or characterized by their function in the composition
    • C08L2666/02—Organic macromolecular compounds, natural resins, waxes or and bituminous materials
    • C08L2666/14—Macromolecular compounds according to C08L59/00 - C08L87/00; Derivatives thereof
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S606/00—Surgery
    • Y10S606/907—Composed of particular material or coated
    • Y10S606/91—Polymer

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Dermatology (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Transplantation (AREA)
  • Materials Engineering (AREA)
  • Composite Materials (AREA)
  • Surgery (AREA)
  • Polymers & Plastics (AREA)
  • Inorganic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Rheumatology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Oncology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Pain & Pain Management (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Communicable Diseases (AREA)
  • Materials For Medical Uses (AREA)
  • Medicinal Preparation (AREA)
  • Compositions Of Macromolecular Compounds (AREA)
  • Adhesives Or Adhesive Processes (AREA)
  • Detergent Compositions (AREA)
  • Lubricants (AREA)
TW093103318A 2003-02-12 2004-02-12 Random and non-random alkylene oxide polymer alloy compositions TWI367113B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US44653403P 2003-02-12 2003-02-12

Publications (2)

Publication Number Publication Date
TW200507888A TW200507888A (en) 2005-03-01
TWI367113B true TWI367113B (en) 2012-07-01

Family

ID=32869526

Family Applications (2)

Application Number Title Priority Date Filing Date
TW093103325A TW200507826A (en) 2003-02-12 2004-02-12 Random alkylene oxide copolymers for medical and surgical utilities
TW093103318A TWI367113B (en) 2003-02-12 2004-02-12 Random and non-random alkylene oxide polymer alloy compositions

Family Applications Before (1)

Application Number Title Priority Date Filing Date
TW093103325A TW200507826A (en) 2003-02-12 2004-02-12 Random alkylene oxide copolymers for medical and surgical utilities

Country Status (9)

Country Link
US (6) US20060140904A1 (zh)
EP (2) EP1601326A4 (zh)
JP (2) JP5508661B2 (zh)
CN (1) CN1780596B (zh)
AU (1) AU2004211991B2 (zh)
CA (1) CA2515292C (zh)
ES (1) ES2695401T3 (zh)
TW (2) TW200507826A (zh)
WO (2) WO2004071451A2 (zh)

Families Citing this family (43)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7763769B2 (en) 2001-02-16 2010-07-27 Kci Licensing, Inc. Biocompatible wound dressing
US7700819B2 (en) 2001-02-16 2010-04-20 Kci Licensing, Inc. Biocompatible wound dressing
WO2004071451A2 (en) * 2003-02-12 2004-08-26 Ceremed, Inc. Random alkylene oxide copolymers for medical and surgical utilities
US7955616B2 (en) * 2003-09-23 2011-06-07 Orthocon, Inc. Absorbable implants and methods for their use in hemostasis and in the treatment of osseous defects
JP3930896B1 (ja) * 2005-12-28 2007-06-13 株式会社メンテック 機能性組成物、及びそれを用いた湿紙の剥離性向上方法
US20070232762A1 (en) * 2006-03-31 2007-10-04 Depuy Products, Inc. Bearing material of medical implant having reduced wear rate and method for reducing wear rate
US7812098B2 (en) 2006-03-31 2010-10-12 Depuy Products, Inc. Bearing material of medical implant having reduced wear rate and method for reducing wear rate
ES2813851T3 (es) * 2006-05-22 2021-03-25 Syncera Inc Composiciones poliméricas reabsorbibles para su uso en medicina, odontología y cirugía
CN101622294B (zh) * 2007-01-17 2012-07-04 陶氏环球技术有限责任公司 润滑剂组合物和制备其的方法
US8480651B2 (en) * 2007-08-02 2013-07-09 Covidien Lp Cannula system
CA2716010C (en) * 2008-04-03 2019-10-01 Zymogenetics, Inc. Hemostatic microspheres
US20110039739A1 (en) * 2008-04-28 2011-02-17 Martin Greaves Polyalkylene glycol-based wind turbine lubricant compositions
DK2299953T3 (en) 2008-07-14 2017-06-19 Polypid Ltd CARBON COMPOSITION FOR MEDICINAL PRODUCTS WITH CONTINUOUS EXPOSURE
US8992979B2 (en) * 2009-07-14 2015-03-31 Polypid Ltd. Sustained-release drug carrier composition
MY159238A (en) * 2009-08-18 2016-12-30 Shell Int Research Fuel and engine oil composition and its use
US20110207084A1 (en) * 2010-01-13 2011-08-25 Kaigler Sr Darnell Method and apparatus for bone distraction
US20110171596A1 (en) * 2010-01-14 2011-07-14 Clark David J Dental Wedge
CA2783001C (en) 2010-01-19 2017-12-12 Polypid Ltd. Sustained-release nucleic acid matrix compositions
CA2796274A1 (en) * 2010-04-16 2011-10-20 Apatech Limited Biomaterial
WO2011137231A1 (en) * 2010-04-29 2011-11-03 Warsaw Orthopedic, Inc. Flowable ceramic putty
JP5634754B2 (ja) * 2010-06-03 2014-12-03 智広 梅田 骨止血組成物
CN101864103B (zh) * 2010-07-02 2012-08-08 天津市医疗器械厂 宫内节育器用混合料
WO2012047290A1 (en) * 2010-10-05 2012-04-12 Theracell, Inc. & Yissum Research Development Company Of The Hebrew University Of Jerusalem, Ltd. Oxygenated demineralized bone matrix for use in bone growth
DE102011016277B4 (de) 2011-04-06 2013-02-21 Heraeus Medical Gmbh Plastisch verformbares, biodegradierbares Hämostyptikum und Verfahren zum Formen eines solchen
WO2013014677A1 (en) * 2011-07-27 2013-01-31 Polypid Ltd. Matrix compositions for controlled release of peptide and polypeptide molecules
US20130287818A1 (en) 2011-10-28 2013-10-31 Baxter Healthcare S.A. Non-aqueous compositions and methods for bone hemostasis
WO2013067154A1 (en) 2011-11-01 2013-05-10 Orthocon, Inc. Compositions and methods for hemostasis
US8992949B1 (en) 2011-11-17 2015-03-31 Unicare Biomedical, Inc. Biocompatible polymeric compositions having microcrystalline and amorphous components and methods for their manufacture
CA2895482A1 (en) * 2012-12-18 2014-06-26 Novabone Products, Llc Bioactive glass with ethylene oxide propylene oxide block copolymers
US8859007B2 (en) 2013-01-13 2014-10-14 Theracell, Inc. Oxygenated demineralized bone matrix for bone growth
AU2015236008B2 (en) * 2014-03-25 2018-12-20 Genentech, Inc. Methods of preparing a poloxamer for use in cell culture medium
CA2951197C (en) 2014-06-04 2022-07-19 David J. Clark Dental wedge
US10201338B1 (en) 2014-09-10 2019-02-12 Abyrx, Inc. Device for the application of surgical materials to tissue
GB2533342A (en) * 2014-12-17 2016-06-22 Ibm Checkpointing module and method for storing checkpoints
US10743996B2 (en) 2017-03-24 2020-08-18 Robert L. Bundy Amnion putty for cartilage repair
EP3381479A1 (de) * 2017-03-29 2018-10-03 ARTOSS GmbH Trägerzusammensetzung für knochenersatzmaterialien
US11103618B2 (en) 2018-02-22 2021-08-31 Warsaw Orthopedic, Inc. Demineralized bone matrix having improved handling characteristics
EP3539571B1 (en) 2018-03-16 2023-05-31 Critical Innovations, LLC Systems and methods relating to medical applications of synthetic polymer formulations
KR102211765B1 (ko) * 2019-01-15 2021-02-03 주식회사 테라시온바이오메디칼 흡수성 골 지혈재 조성물 및 이를 이용한 골 지혈재 제조방법
US11369473B2 (en) 2019-04-08 2022-06-28 Loubert S. Suddaby Extended release immunomodulatory implant to facilitate bone morphogenesis
US11779683B2 (en) 2019-04-08 2023-10-10 Loubert S. Suddaby Extended release immunomodulatory implant to facilitate bone morphogenesis
WO2021030550A1 (en) * 2019-08-13 2021-02-18 Mccord Darlene E NON-ACTIVATED, AMORPHOUS, pH NEUTRAL, TWO-PART BEDSIDE-READY CLAY DELIVERY SYSTEM THAT TREATS PATHOGEN INFECTIONS IN HUMANS AND ANIMALS
JP7301427B2 (ja) 2022-05-13 2023-07-03 カシン工業株式会社 絶縁型ヒータおよびヒータ装置

Family Cites Families (95)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE322412B (zh) * 1968-09-10 1970-04-06 Mo Och Domsjoe Ab
US3634305A (en) * 1969-08-08 1972-01-11 Wyandotte Chemicals Corp Water-soluble compositions resistant to shear degradation of the polymer thereof
US3862311A (en) * 1971-04-12 1975-01-21 Ciba Geigy Corp Novel method of enhancing progestational endometrial proliferation with progesterone
US3903232A (en) * 1973-10-09 1975-09-02 Grace W R & Co Dental and biomedical foams and method
US4038388A (en) * 1974-03-29 1977-07-26 Paterson Zochonis & Company Limited Antimicrobial compositions
US3939261A (en) * 1974-08-30 1976-02-17 Colgate-Palmolive Company Flavored dentifrice
US4027676A (en) * 1975-01-07 1977-06-07 Ethicon, Inc. Coated sutures
US4013622A (en) * 1975-06-23 1977-03-22 Cities Service Company Method of reducing breakdown in polyethylene film
DE2546371A1 (de) * 1975-10-16 1977-04-21 Sandoz Ag Neue galenische formen
US4125470A (en) * 1976-04-02 1978-11-14 Dow Corning Corporation Band-ply lubricant concentrates
US4043344A (en) * 1976-09-20 1977-08-23 American Cyanamid Company Non-absorbable surgical sutures coated with polyoxyethylene-polyoxypropylene copolymer lubricant
US4047533A (en) * 1976-09-20 1977-09-13 American Cyanamid Company Absorbable surgical sutures coated with polyoxyethylene-polyoxypropylene copolymer lubricant
US4201216A (en) * 1976-12-15 1980-05-06 Ethicon, Inc. Absorbable coating composition for sutures
JPS55147597A (en) * 1979-05-04 1980-11-17 Mikasa Kagaku Kogyo Kk Treating composition for washing water of stool
US4407953A (en) * 1982-05-24 1983-10-04 Pfizer Inc. Fermentation process for production of alpha-isopropylmalic acid
DE3224784C2 (de) * 1982-07-01 1984-04-26 Siemens AG, 1000 Berlin und 8000 München Kabelgleitmittel
US4439420A (en) * 1982-11-16 1984-03-27 Ethicon, Inc. Absorbable hemostatic composition
USRE32208E (en) * 1982-11-16 1986-07-15 Ethicon, Inc. Absorbable hemostatic composition
US4443430A (en) * 1982-11-16 1984-04-17 Ethicon, Inc. Synthetic absorbable hemostatic agent
US4470416A (en) * 1983-06-17 1984-09-11 Ethicon, Inc. Copolymers of lactide and/or glycolide with 1,5-dioxepan-2-one
US4684524A (en) * 1984-03-19 1987-08-04 Alza Corporation Rate controlled dispenser for administering beneficial agent
CA1290202C (en) * 1985-07-02 1991-10-08 Mikhail M. Girgis Chemically treated glass fibers
US4716203A (en) * 1986-09-05 1987-12-29 American Cyanamid Company Diblock and triblock copolymers
WO1988001878A1 (en) * 1986-09-20 1988-03-24 Smith And Nephew Associated Companies Plc Adhesive dressing
US5283067A (en) * 1987-01-30 1994-02-01 Ciba-Geigy Corporation Parenteral suspensions
GB8802959D0 (en) * 1988-02-09 1988-03-09 Bp Chem Int Ltd Composition for removing asbestos
US5962028A (en) * 1988-04-20 1999-10-05 Norian Corporation Carbonated hydroxyapatite compositions and uses
US5447966A (en) * 1988-07-19 1995-09-05 United States Surgical Corporation Treating bioabsorbable surgical articles by coating with glycerine, polalkyleneoxide block copolymer and gelatin
DE3825211A1 (de) * 1988-07-25 1990-02-01 Henkel Kgaa Verbesserte koerperresorbierbare knochenwachse (iii)
DE3832877A1 (de) * 1988-09-28 1990-04-12 Hoechst Ag Organische dispersionspolymerisate auf der basis von ethylenisch ungesaettigten monameren, die wasserloesliche und vinylalkoholeinheiten mit einer polyurethanpfropfgrundlage enthaltende pfropfpolymerisate enthalten, verfahren zu ihrer herstellung und ihre verwendung
US5487897A (en) * 1989-07-24 1996-01-30 Atrix Laboratories, Inc. Biodegradable implant precursor
DE3927113C2 (de) * 1989-08-17 1993-11-25 Dolorgiet Gmbh & Co Kg Mittel zur Behandlung von schweren Schmerzzuständen und Verfahren zu ihrer Herstellung
ATE127129T1 (de) * 1989-10-30 1995-09-15 Fina Research Verfahren zur herstellung von polyolefinpulver mit kontrollierter morphologie unter anwendung eines metallocenhaltigen katalytorsystems.
JP2928892B2 (ja) 1990-11-27 1999-08-03 三洋化成工業株式会社 外科用接着剤
US5286300A (en) * 1991-02-13 1994-02-15 Man-Gill Chemical Company Rinse aid and lubricant
CA2063278A1 (en) * 1991-06-05 1992-12-06 Jeffrey I. Melzer Composition and process for enhanced drainage of residual aqueous rinse on the external surfaces of plastic parts
US5330768A (en) * 1991-07-05 1994-07-19 Massachusetts Institute Of Technology Controlled drug delivery using polymer/pluronic blends
US5417808A (en) * 1991-08-30 1995-05-23 Lion Corporation Deinking composition for flotation and deinking method
US6376588B1 (en) * 1991-10-15 2002-04-23 Huntsman Petrochemical Corporation Water soluble mold release composition for elastomeric compounds
US6537574B1 (en) * 1992-02-11 2003-03-25 Bioform, Inc. Soft tissue augmentation material
US5352515A (en) * 1992-03-02 1994-10-04 American Cyanamid Company Coating for tissue drag reduction
CA2092646A1 (en) 1992-03-25 1993-09-26 Ross R. Muth Bioabsorbable blends of a bioabsorbable copolymer and a poly(oxyalkylene)
US5545226A (en) * 1992-05-29 1996-08-13 Porex Technologies Corp. Implants for cranioplasty
US6592859B1 (en) * 1992-08-20 2003-07-15 Ethicon, Inc. Controlled expansion sphincter augmentation media
US5817321A (en) * 1992-10-08 1998-10-06 Supratek Pharma, Inc. Biological agent compositions
US5840319A (en) * 1992-10-08 1998-11-24 Alakhov; Valery Yu Biological agent compositions
CA2114290C (en) * 1993-01-27 2006-01-10 Nagabushanam Totakura Post-surgical anti-adhesion device
US5503558A (en) * 1993-11-12 1996-04-02 Mcgill University Osseointegration promoting implant composition, implant assembly and method therefor
JPH07179804A (ja) 1993-12-22 1995-07-18 Pilot Corp:The 水性ボールペンに使用する直詰用インクとこのインクを直詰したキャップ式ボールペン
US5840338A (en) * 1994-07-18 1998-11-24 Roos; Eric J. Loading of biologically active solutes into polymer gels
US5520923A (en) * 1994-09-19 1996-05-28 Genetics Institute, Inc. Formulations for delivery of osteogenic proteins
US5912228A (en) * 1995-01-13 1999-06-15 Xoma Corporation Therapeutic compositions comprising bactericidal/permeability-increasing (BPI) protein products
US6017577A (en) * 1995-02-01 2000-01-25 Schneider (Usa) Inc. Slippery, tenaciously adhering hydrophilic polyurethane hydrogel coatings, coated polymer substrate materials, and coated medical devices
US5939485A (en) * 1995-06-19 1999-08-17 Medlogic Global Corporation Responsive polymer networks and methods of their use
US5641502A (en) * 1995-06-07 1997-06-24 United States Surgical Corporation Biodegradable moldable surgical material
JPH09143093A (ja) * 1995-11-17 1997-06-03 Hoechst Japan Ltd 軟骨・骨誘導性修復用材料
US6143037A (en) * 1996-06-12 2000-11-07 The Regents Of The University Of Michigan Compositions and methods for coating medical devices
US6060518A (en) * 1996-08-16 2000-05-09 Supratek Pharma Inc. Polymer compositions for chemotherapy and methods of treatment using the same
US6331289B1 (en) * 1996-10-28 2001-12-18 Nycomed Imaging As Targeted diagnostic/therapeutic agents having more than one different vectors
TW358116B (en) * 1996-12-09 1999-05-11 Mitsubishi Pencil Co Ballpen aqueous ink component
US6143276A (en) * 1997-03-21 2000-11-07 Imarx Pharmaceutical Corp. Methods for delivering bioactive agents to regions of elevated temperatures
CA2301921A1 (en) * 1997-08-20 1999-02-25 John Graham Goddard Compositions containing polyethylene glycol and uses thereof
US6309659B1 (en) * 1997-09-02 2001-10-30 Gensci Orthobiologics, Inc. Reverse phase connective tissue repair composition
US5885597A (en) * 1997-10-01 1999-03-23 Medical Research Industries,Inc. Topical composition for the relief of pain
US6417247B1 (en) * 1997-10-14 2002-07-09 Beth L. Armstrong Polymer/ceramic composites
US6437018B1 (en) * 1998-02-27 2002-08-20 Musculoskeletal Transplant Foundation Malleable paste with high molecular weight buffered carrier for filling bone defects
US5968480A (en) * 1998-07-09 1999-10-19 Colgate Palmolive Company Oral composition exhibiting enhanced antiplaque efficacy
CA2244017A1 (en) * 1998-07-28 2000-01-28 Stephane Tetreault Moisture-curable adhesive suture strip
US6406498B1 (en) * 1998-09-04 2002-06-18 Bionx Implants Oy Bioactive, bioabsorbable surgical composite material
AU768641B2 (en) * 1998-10-12 2003-12-18 Massachusetts Institute Of Technology Composites for tissue regeneration and methods of manufacture thereof
US7168086B1 (en) * 1998-11-30 2007-01-23 Microsoft Corporation Proxy for video on demand server control
AU2196400A (en) * 1998-12-18 2000-07-03 Medlogic Global Corporation Cyanoacrylate compositions comprising a soluble antimicrobial agent
US6762339B1 (en) * 1999-05-21 2004-07-13 3M Innovative Properties Company Hydrophilic polypropylene fibers having antimicrobial activity
US9616150B2 (en) * 1999-10-29 2017-04-11 Children's Hospital Los Angeles Bone hemostasis method and materials
EP1231869B1 (en) 1999-10-29 2005-09-21 Children's Hospital of Los Angeles Bone hemostasis method and materials
US6328990B1 (en) * 1999-11-12 2001-12-11 The Trustees Of The University Of Pennsylvania Bioactive, degradable composite for tissue engineering
US6461631B1 (en) * 1999-11-16 2002-10-08 Atrix Laboratories, Inc. Biodegradable polymer composition
JP2001172411A (ja) * 1999-12-20 2001-06-26 Toyobo Co Ltd 熱可塑性ポリエステルエラストマーフィルム
US20020025340A1 (en) * 2000-08-30 2002-02-28 Dyer Wallace K. Methods and compositions for tissue augmentation
US6296607B1 (en) * 2000-10-20 2001-10-02 Praxis, Llc. In situ bulking device
JP2002322235A (ja) * 2001-04-24 2002-11-08 Nippon Polyurethane Ind Co Ltd 軟質ポリウレタンフォームの製造方法
US6685956B2 (en) * 2001-05-16 2004-02-03 The Research Foundation At State University Of New York Biodegradable and/or bioabsorbable fibrous articles and methods for using the articles for medical applications
US20030082235A1 (en) * 2001-08-13 2003-05-01 Yissum Research Development Company Of The Hebrew University Of Jerusalem Novel reverse thermo-sensitive block copolymers
IL151288A0 (en) * 2001-08-27 2003-04-10 Yissum Res Dev Co Multi-component reverse thermo-sensitive polymeric systems
US20030190336A1 (en) * 2002-03-18 2003-10-09 Adams Christine Helga Personal care compositions comprising solid particles enterapped in a gel network
JP4324341B2 (ja) * 2002-03-22 2009-09-02 ディバーシー・アイピー・インターナショナル・ビー・ヴイ 自動食器洗浄機用液体洗浄剤組成物
WO2003080119A1 (en) * 2002-03-26 2003-10-02 Yissum Research Development Company Of The Hebrew University Of Jerusalem Responsive biomedical composites
CA2505821C (en) * 2002-11-12 2012-08-21 The Polymer Technology Group Incorporated Control of polymer surface molecular architecture via amphipathic endgroups
WO2004071451A2 (en) 2003-02-12 2004-08-26 Ceremed, Inc. Random alkylene oxide copolymers for medical and surgical utilities
IL155866A0 (en) * 2003-05-12 2003-12-23 Yissum Res Dev Co Responsive polymeric system
FR2859988A1 (fr) 2003-09-18 2005-03-25 Nanoledge Dispersion de nanotubes dans des solvants organiques
US20060008609A1 (en) * 2004-01-26 2006-01-12 Snyder Glenn E Sandwich panel and method of manufacturing same
US20050215748A1 (en) * 2004-03-29 2005-09-29 Milbocker Michael T Surgical adhesive formulations and methods of preparation
ITBO20040629A1 (it) * 2004-10-14 2005-01-14 Marchesini Group Spa Sistema per la trasmissione del moto tra organi separati da una parete divisoria
CA2526541C (en) 2004-12-01 2013-09-03 Tyco Healthcare Group Lp Novel biomaterial drug delivery and surface modification compositions

Also Published As

Publication number Publication date
WO2004071451A3 (en) 2005-09-22
US7553913B2 (en) 2009-06-30
CA2515292C (en) 2015-09-29
EP1596767A2 (en) 2005-11-23
JP2012136703A (ja) 2012-07-19
WO2004071451A2 (en) 2004-08-26
US20110002974A1 (en) 2011-01-06
US20060100370A1 (en) 2006-05-11
WO2004071452A2 (en) 2004-08-26
US7829616B2 (en) 2010-11-09
US20110002915A1 (en) 2011-01-06
EP1596767A4 (en) 2010-10-27
WO2004071452A3 (en) 2004-11-11
TW200507826A (en) 2005-03-01
TW200507888A (en) 2005-03-01
EP1601326A4 (en) 2011-05-11
JP2006521425A (ja) 2006-09-21
EP1601326A2 (en) 2005-12-07
JP5508661B2 (ja) 2014-06-04
CA2515292A1 (en) 2004-08-26
AU2004211991B2 (en) 2011-03-31
EP1596767B1 (en) 2018-10-03
ES2695401T3 (es) 2019-01-04
AU2004211991A1 (en) 2004-08-26
US20090238758A1 (en) 2009-09-24
JP5282150B2 (ja) 2013-09-04
CN1780596A (zh) 2006-05-31
CN1780596B (zh) 2010-12-15
US20060140904A1 (en) 2006-06-29
US9919074B2 (en) 2018-03-20
US20120219497A1 (en) 2012-08-30
US8124687B2 (en) 2012-02-28

Similar Documents

Publication Publication Date Title
TWI367113B (en) Random and non-random alkylene oxide polymer alloy compositions
HK1077310A1 (en) Hydrogenated copolymer and composition thereof
MX271467B (es) Composicion para la limpieza personal que contiene particulas de forma irregular y particulas esfericas.
HK1180218A1 (zh) 包含 的組合物和方法
IL174636A0 (en) Compositions containing anti-scarring agents and medical implants incorporating the same
GB0411940D0 (en) Methods and compositions
AU2003271498A8 (en) Coolant solutions and compositions comprising the sameitle
ZA200602885B (en) Antimicrobial compositions and methods
AU2002357119A8 (en) Mitocidal compositions and methods
HK1153229A1 (zh) 小細胞組合物和方法
EP1589071A4 (en) POLYETHEROL POLYOL COMPOSITION AND USE THEREOF
GB2395952B (en) Block copolymer and use thereof
EP1413589A4 (en) ORAL POLYMERS AND ORAL COMPOSITIONS
AU2002357748A8 (en) Osteopontin-related compositions and methods
AP2006003557A0 (en) Antimalarial compositions and process thereof.
HRP20140660T1 (en) Compositions and uses therof
EP1670893A4 (en) IMMUNOGENEOUS HIV COMPOSITIONS AND METHODS CONNECTED THEREWITH
EP1620089A4 (en) Therapeutic and prophylactic compositions and their uses
AU2003268318A8 (en) In situ polymerizing medical compositions
TWI350750B (en) Compositions comprising cyclohexylamines and aminoadamantanes
AU2002306461A1 (en) In vivo delivery methods and compositions
EP1358203A4 (en) METHOD AND COMPOSITION FOR CONNECTING IN SPLICEOSOME-MEDIATED RNA TRANS SPLICING
AU2002366809A8 (en) Syn3 compositions and methods
GB0417125D0 (en) Improvements in personal care and other compositions
EP1402892A4 (en) ANTI-INFLAMMATORY AND ANTITUSSIVE COMPOSITIONS

Legal Events

Date Code Title Description
MK4A Expiration of patent term of an invention patent