TWI366466B - Herbal extracts capable of inducing immune cells to produce interferon and activating toll-like receptors and the preparation thereof - Google Patents

Herbal extracts capable of inducing immune cells to produce interferon and activating toll-like receptors and the preparation thereof

Info

Publication number
TWI366466B
TWI366466B TW097116973A TW97116973A TWI366466B TW I366466 B TWI366466 B TW I366466B TW 097116973 A TW097116973 A TW 097116973A TW 97116973 A TW97116973 A TW 97116973A TW I366466 B TWI366466 B TW I366466B
Authority
TW
Taiwan
Prior art keywords
receptors
preparation
immune cells
herbal extracts
inducing immune
Prior art date
Application number
TW097116973A
Other languages
English (en)
Other versions
TW200946124A (en
Inventor
I Horng Pan
Lain Tze Lee
Chih Lung Chen
Hsin Jan Yao
Chu Hsun Lu
Chen Hsuan Lin
ya yan Yang
Hsin Hsin Shen
Ming Feng Chen
Original Assignee
Ind Tech Res Inst
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ind Tech Res Inst filed Critical Ind Tech Res Inst
Priority to TW097116973A priority Critical patent/TWI366466B/zh
Priority to US12/164,958 priority patent/US20090280200A1/en
Priority to JP2008171397A priority patent/JP4980305B2/ja
Publication of TW200946124A publication Critical patent/TW200946124A/zh
Application granted granted Critical
Publication of TWI366466B publication Critical patent/TWI366466B/zh

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/65—Paeoniaceae (Peony family), e.g. Chinese peony
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/23—Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
    • A61K36/233—Bupleurum
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
    • A61K36/484—Glycyrrhiza (licorice)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/53—Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
    • A61K36/539—Scutellaria (skullcap)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/79—Schisandraceae (Schisandra family)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/10—Antimycotics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A61P31/18—Antivirals for RNA viruses for HIV
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A61P33/02—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/02—Antineoplastic agents specific for leukemia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/04—Immunostimulants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid

Landscapes

  • Health & Medical Sciences (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Botany (AREA)
  • Epidemiology (AREA)
  • Mycology (AREA)
  • Microbiology (AREA)
  • Medical Informatics (AREA)
  • Biotechnology (AREA)
  • Alternative & Traditional Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Oncology (AREA)
  • Immunology (AREA)
  • Communicable Diseases (AREA)
  • Virology (AREA)
  • Neurosurgery (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Hematology (AREA)
  • Molecular Biology (AREA)
  • AIDS & HIV (AREA)
  • Endocrinology (AREA)
  • Reproductive Health (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Diabetes (AREA)
  • Medicinal Preparation (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
TW097116973A 2008-05-08 2008-05-08 Herbal extracts capable of inducing immune cells to produce interferon and activating toll-like receptors and the preparation thereof TWI366466B (en)

Priority Applications (3)

Application Number Priority Date Filing Date Title
TW097116973A TWI366466B (en) 2008-05-08 2008-05-08 Herbal extracts capable of inducing immune cells to produce interferon and activating toll-like receptors and the preparation thereof
US12/164,958 US20090280200A1 (en) 2008-05-08 2008-06-30 Herbal extracts which induce immune cells to produce interferon and activate toll-like receptors
JP2008171397A JP4980305B2 (ja) 2008-05-08 2008-06-30 免疫細胞のインターフェロン産生を誘導し、Ｔｏｌｌ様受容体を活性化する漢方生薬エキス

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
TW097116973A TWI366466B (en) 2008-05-08 2008-05-08 Herbal extracts capable of inducing immune cells to produce interferon and activating toll-like receptors and the preparation thereof

Publications (2)

Publication Number Publication Date
TW200946124A TW200946124A (en) 2009-11-16
TWI366466B true TWI366466B (en) 2012-06-21

Family

ID=41267053

Family Applications (1)

Application Number Title Priority Date Filing Date
TW097116973A TWI366466B (en) 2008-05-08 2008-05-08 Herbal extracts capable of inducing immune cells to produce interferon and activating toll-like receptors and the preparation thereof

Country Status (3)

Country Link
US (1) US20090280200A1 (zh)
JP (1) JP4980305B2 (zh)
TW (1) TWI366466B (zh)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP5375557B2 (ja) 2009-03-27 2013-12-25 日産自動車株式会社 車両用アクセルペダル反力付与装置及びその方法
US8597693B2 (en) * 2010-07-01 2013-12-03 Industrial Technology Research Institute Pharmaceutical composition with immunomodulating function
TWI401088B (zh) * 2011-01-24 2013-07-11 Nat Defense Medical Ct Schisandra extract is used to prepare a medicament for inhibiting or preventing H1N1 influenza virus infection
CN102614465B (zh) * 2012-04-16 2014-12-10 山东省中医药研究院 一种治疗慢性乙型肝炎的中药复方制剂及其制备方法
CN103223050A (zh) * 2013-04-16 2013-07-31 阚兆云 一种中药提取物及其制备方法
CN103417654B (zh) * 2013-08-12 2016-02-10 河南惠通天下生物工程有限公司 一种防治禽类球虫病的中药组合物及其制备方法
CN103432276B (zh) * 2013-09-16 2015-03-25 河北科技师范学院 治疗仔猪急性副伤寒的中草药口服液
KR101673894B1 (ko) * 2014-03-31 2016-11-09 강원대학교산학협력단 황금 추출물 및 이로부터 분리된 화합물을 유효성분으로 함유하는 엔테로 바이러스에 기인한 질환의 예방 및 치료용 조성물
CN104547035A (zh) * 2014-12-19 2015-04-29 陕西必康制药集团控股有限公司 五味子的提取方法
CN104491007A (zh) * 2014-12-19 2015-04-08 陕西必康制药集团控股有限公司 五味子软胶囊的制备方法
KR101646009B1 (ko) * 2015-11-25 2016-08-08 강원대학교산학협력단 오록실린(oroxylin) A 화합물을 유효성분으로 함유하는 엔테로 바이러스에 기인한 질환의 예방 및 치료용 조성물
KR101643200B1 (ko) * 2015-11-25 2016-07-27 강원대학교산학협력단 모슬로플라본(mosloflavone) 화합물을 유효성분으로 함유하는 엔테로 바이러스에 기인한 질환의 예방 및 치료용 조성물
CN115645328A (zh) * 2022-10-25 2023-01-31 兰树化妆品股份有限公司 一种芍药提取物及其制备方法和应用

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1082421A (zh) * 1992-04-17 1994-02-23 金钟国 牛黄清心微型胶囊及其制造方法
AUPN411195A0 (en) * 1995-07-10 1995-08-03 Cathay Herbal Laboratories Pty Ltd Medicinal composition
US5837257A (en) * 1996-07-09 1998-11-17 Sage R&D Use of plant extracts for treatment of HIV, HCV and HBV infections
CN1173357A (zh) * 1997-04-27 1998-02-18 韦良晋 乙肝服复转阴丸
CN1060384C (zh) * 1997-08-01 2001-01-10 阮可才 一种抗衰老药物口服液及其制备方法
AU4550801A (en) * 2000-03-09 2001-09-17 Univ Yale Herbal composition phy906 and its use in chemotheraphy
US6455078B1 (en) * 2000-10-18 2002-09-24 Tzu-Sheng Wu Medicinal herbal composition for treating liver diseases and HIV
US6696094B2 (en) * 2000-10-18 2004-02-24 Tzu-Sheng Wu Herbal pharmaceutical composition for treatment of HIV/AIDS patients
CN1309399C (zh) * 2000-10-25 2007-04-11 国家中药制药工程技术研究中心 复方双黄连制剂及制备方法
US6613362B2 (en) * 2002-01-08 2003-09-02 Renew Life Formulas, Inc. Herbal formulation which acts as an intestinal bowel soother
US20050032882A1 (en) * 2002-03-06 2005-02-10 Sophie Chen Botanical extract compositions and methods of use
AU2003228777C1 (en) * 2002-04-30 2009-08-13 Unigen, Inc. Formulation of a mixture of free-B-ring flavonoids and flavans as a therapeutic agent
CN1186059C (zh) * 2002-08-28 2005-01-26 唐启盛 一种治疗抑郁症、焦虑症的中药制剂
BRPI0409179A (pt) * 2003-04-04 2006-05-02 Unigen Pharmaceuticals Inc formulação de inibidores duplos de ciclooxigenase (cox) e lipoxigenase (lox) para cuidados com a pele de mamìferos
MX2007011065A (es) * 2005-03-10 2007-11-07 Unigen Pharmaceuticals Inc Formulacion de una mezcla de flavonoides libres de anillo b y flavanos como un agente terapeutico.

Also Published As

Publication number Publication date
TW200946124A (en) 2009-11-16
JP2009269902A (ja) 2009-11-19
US20090280200A1 (en) 2009-11-12
JP4980305B2 (ja) 2012-07-18

Similar Documents

Publication Publication Date Title
TWI366466B (en) Herbal extracts capable of inducing immune cells to produce interferon and activating toll-like receptors and the preparation thereof
HRP20181343T1 (hr) Postupci i pripravci za induciranje imunosnog odgovora na egfrviii
IL252490A0 (en) Ceramic-ceramic bonding and related methods
HRP20140203T1 (hr) Pripravci i metode za jaäśanje imunološkog sustava
IL232276A0 (en) Antibodies to 6-il and their uses
HK1128421A1 (en) Process of preparation of extracts rich in proanthocyanidins
EP2069381A4 (en) MEDIUM AND METHOD FOR TRIGGERING AN ANTITUMOR IMMUNE REACTION
EP2504031A4 (en) ANTI-IL-6 ANTIBODIES AND THEIR USE
EP2182965A4 (en) LIGUSTRUM LUCIDUM EXTRACTS AND USES THEREOF
HK1146575A1 (zh) 提高針對艾美球蟲的免疫反應的成分和方法
EP2517252A4 (en) METHOD AND CONFIGURATIONS FOR INSERTING STRANDS IN DEVICES WITH INTEGRATED CIRCUITS
IL218960A (en) Immunogenic oligomeric influenza preparations to enhance and respond to exercise response
GB201021244D0 (en) Improvements in and relating to aircraft
EP2358733A4 (en) ANTIGENS TO ENHANCE IMMUNE RESPONSE AGAINST FLAVIVIRES AND METHOD OF USE THEREOF
HK1167879A1 (en) Improvements in and relating to posts
ZA201003964B (en) Compositions for and methods of enhancing the immune response to antigens
GB0914582D0 (en) Improvements in and relating to an led assembly
AU2011352504A1 (en) Moisture-retaining chinese herbal medicine composition and preparation method and use thereof
EP2334701A4 (en) FULLY HUMAN ANTIBODIES AGAINST ANTIGENES ASSOCIATED WITH MELANOMA OF HIGH MOLECULAR WEIGHT AND USES THEREOF
HK1181635A1 (zh) 具有不同表面光潔度的零件及其生產方法
AU2011352576A1 (en) Anti-aging traditional Chinese medicinal herbal composition and preparation method and use thereof
EP2352489A4 (en) PREPARATION AND USE OF POUTERIA LUCUMA EXTRACT &xA;
GB2456130B (en) Improvements in and relating to the preparation of specimens
TWM386329U (en) Improved structure of natural marble and granite waterproof composite sheet
GB0915978D0 (en) Improvements in and relating to buildings