TWI346700B - The il-1 gene cluster and associated inflammatory polymorphisms and haplotypes - Google Patents

The il-1 gene cluster and associated inflammatory polymorphisms and haplotypes

Info

Publication number
TWI346700B
TWI346700B TW092101760A TW92101760A TWI346700B TW I346700 B TWI346700 B TW I346700B TW 092101760 A TW092101760 A TW 092101760A TW 92101760 A TW92101760 A TW 92101760A TW I346700 B TWI346700 B TW I346700B
Authority
TW
Taiwan
Prior art keywords
haplotypes
polymorphisms
gene cluster
associated inflammatory
inflammatory
Prior art date
Application number
TW092101760A
Other languages
English (en)
Chinese (zh)
Other versions
TW200401035A (en
Inventor
Nicklin Martin
W Duff Gordon
S Kornman Kenneth
Cannings Chris
Rafie Kolpin Maryam
Hsieh Chung-Ming
Govindaraju Raju
Aziz Nazneen
Original Assignee
Interleukin Genetics Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Interleukin Genetics Inc filed Critical Interleukin Genetics Inc
Publication of TW200401035A publication Critical patent/TW200401035A/zh
Application granted granted Critical
Publication of TWI346700B publication Critical patent/TWI346700B/zh

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2501/00—Active agents used in cell culture processes, e.g. differentation
    • C12N2501/20—Cytokines; Chemokines
    • C12N2501/23—Interleukins [IL]
    • C12N2501/2301—Interleukin-1 (IL-1)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/156—Polymorphic or mutational markers

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Wood Science & Technology (AREA)
  • Analytical Chemistry (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Pathology (AREA)
  • Immunology (AREA)
  • Microbiology (AREA)
  • Molecular Biology (AREA)
  • Biotechnology (AREA)
  • Biophysics (AREA)
  • Physics & Mathematics (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
TW092101760A 2002-01-25 2003-01-27 The il-1 gene cluster and associated inflammatory polymorphisms and haplotypes TWI346700B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US35195102P 2002-01-25 2002-01-25

Publications (2)

Publication Number Publication Date
TW200401035A TW200401035A (en) 2004-01-16
TWI346700B true TWI346700B (en) 2011-08-11

Family

ID=27663040

Family Applications (1)

Application Number Title Priority Date Filing Date
TW092101760A TWI346700B (en) 2002-01-25 2003-01-27 The il-1 gene cluster and associated inflammatory polymorphisms and haplotypes

Country Status (8)

Country Link
US (1) US20040171038A1 (enExample)
EP (1) EP1572899A4 (enExample)
JP (1) JP2005529585A (enExample)
KR (1) KR100924468B1 (enExample)
CN (1) CN1751127A (enExample)
CA (1) CA2473641A1 (enExample)
TW (1) TWI346700B (enExample)
WO (1) WO2003064600A2 (enExample)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20070264645A1 (en) * 2002-01-25 2007-11-15 Kenneth Kornman IL-1 gene cluster and associated inflammatory polymorphisms and haplotypes
US7584058B2 (en) 2003-02-27 2009-09-01 Methexis Genomics N.V. Genetic diagnosis using multiple sequence variant analysis
EP1951903A2 (en) 2005-10-25 2008-08-06 Interleukin Genetics, Inc. The il-1 gene cluster and associated inflammatory polymorphisms and haplotypes
CA2635690A1 (en) * 2005-12-28 2007-07-05 Centocor, Inc. Markers and methods for assessing and treating psoriasis and related disorders
EP2089538B1 (en) 2006-11-15 2013-08-21 Interleukin Genetics, Inc. The il-1 gene cluster and insulin resistance: associated polymorphisms, haplotypes and methods of using same
DK2283156T3 (en) * 2008-05-02 2016-02-15 Interleukin Genetics Inc Detection of genetic predisposition to conditions associated with osteoarthritis
KR101610861B1 (ko) * 2014-07-28 2016-04-11 (주)케어젠 골분화 촉진능 및 치주인대섬유모세포 활성 촉진능을 갖는 펩타이드 및 이의 용도
JP2018529377A (ja) * 2015-09-01 2018-10-11 リコンビネティクス・インコーポレイテッドＲｅｃｏｍｂｉｎｅｔｉｃｓ，Ｉｎｃ． 所望のハプロタイプ中の外来対立遺伝子の存在を同定する方法
CN114250279B (zh) * 2020-09-22 2024-04-30 上海韦翰斯生物医药科技有限公司 一种单倍型的构建方法

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9621129D0 (en) 1996-10-10 1996-11-27 Duff Gordon W Detecting genetic predisposition to sight-threatening diabetic retinopathy
US7820383B2 (en) * 1997-03-10 2010-10-26 Interleukin Genetics, Inc. Method for diagnosing myocardial infarction
US6524795B1 (en) * 1997-03-10 2003-02-25 Interleukin Genetics, Inc. Diagnostics for cardiovascular disorders
US6210877B1 (en) * 1997-03-10 2001-04-03 Interleukin Genetics, Inc. Prediction of coronary artery disease
GB9711040D0 (en) * 1997-05-29 1997-07-23 Duff Gordon W Prediction of inflammatory disease
US6733967B1 (en) * 1998-04-21 2004-05-11 Interleukin Genetics, Inc. Fetal testing for prediction of low birth weight
CA2382848C (en) * 1999-08-30 2011-01-04 Interleukin Genetics, Inc. Diagnostics and therapeutics for osteoporosis

Also Published As

Publication number Publication date
CN1751127A (zh) 2006-03-22
CA2473641A1 (en) 2003-08-07
EP1572899A4 (en) 2006-10-11
WO2003064600A2 (en) 2003-08-07
KR100924468B1 (ko) 2009-11-03
WO2003064600A3 (en) 2005-10-27
EP1572899A2 (en) 2005-09-14
JP2005529585A (ja) 2005-10-06
US20040171038A1 (en) 2004-09-02
TW200401035A (en) 2004-01-16
KR20040077793A (ko) 2004-09-06

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Legal Events

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MM4A Annulment or lapse of patent due to non-payment of fees