TWI283177B - New use of neurotoxin for treating thyroid and calcemia disorders - Google Patents

New use of neurotoxin for treating thyroid and calcemia disorders Download PDF

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Publication number
TWI283177B
TWI283177B TW090103247A TW90103247A TWI283177B TW I283177 B TWI283177 B TW I283177B TW 090103247 A TW090103247 A TW 090103247A TW 90103247 A TW90103247 A TW 90103247A TW I283177 B TWI283177 B TW I283177B
Authority
TW
Taiwan
Prior art keywords
thyroid
botulinum toxin
units
treatment
cells
Prior art date
Application number
TW090103247A
Other languages
English (en)
Chinese (zh)
Inventor
Stephen Donovan
Original Assignee
Allergan Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Allergan Inc filed Critical Allergan Inc
Application granted granted Critical
Publication of TWI283177B publication Critical patent/TWI283177B/zh

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Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/43Enzymes; Proenzymes; Derivatives thereof
    • A61K38/46Hydrolases (3)
    • A61K38/48Hydrolases (3) acting on peptide bonds (3.4)
    • A61K38/4886Metalloendopeptidases (3.4.24), e.g. collagenase
    • A61K38/4893Botulinum neurotoxin (3.4.24.69)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/12Drugs for disorders of the metabolism for electrolyte homeostasis
    • A61P3/14Drugs for disorders of the metabolism for electrolyte homeostasis for calcium homeostasis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00Drugs for disorders of the endocrine system
    • A61P5/14Drugs for disorders of the endocrine system of the thyroid hormones, e.g. T3, T4
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00Drugs for disorders of the endocrine system
    • A61P5/14Drugs for disorders of the endocrine system of the thyroid hormones, e.g. T3, T4
    • A61P5/16Drugs for disorders of the endocrine system of the thyroid hormones, e.g. T3, T4 for decreasing, blocking or antagonising the activity of the thyroid hormones

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Diabetes (AREA)
  • Endocrinology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Immunology (AREA)
  • Epidemiology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Rheumatology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
TW090103247A 2000-02-15 2001-02-14 New use of neurotoxin for treating thyroid and calcemia disorders TWI283177B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US09/504,538 US6524580B1 (en) 2000-02-15 2000-02-15 Method for treating thyroid disorders

Publications (1)

Publication Number Publication Date
TWI283177B true TWI283177B (en) 2007-07-01

Family

ID=24006701

Family Applications (1)

Application Number Title Priority Date Filing Date
TW090103247A TWI283177B (en) 2000-02-15 2001-02-14 New use of neurotoxin for treating thyroid and calcemia disorders

Country Status (10)

Country Link
US (6) US6524580B1 (https=)
EP (1) EP1253933B1 (https=)
JP (2) JP2003530320A (https=)
AR (1) AR027442A1 (https=)
AT (1) ATE245032T1 (https=)
AU (1) AU2001238369A1 (https=)
DE (1) DE60100473T2 (https=)
ES (1) ES2199209T3 (https=)
TW (1) TWI283177B (https=)
WO (1) WO2001060396A2 (https=)

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CN114746107A (zh) * 2019-10-10 2022-07-12 梅尔兹治疗有限公司 用于预防人腺体遭受放射损伤的方法

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US7514088B2 (en) * 2005-03-15 2009-04-07 Allergan, Inc. Multivalent Clostridial toxin derivatives and methods of their use
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US8105611B2 (en) * 2005-06-17 2012-01-31 Allergan, Inc. Treatment of autoimmune disorder with a neurotoxin
JP5826450B2 (ja) 2005-07-22 2015-12-02 ザ ファウンドリー, エルエルシー 治療薬の送達のためのシステムおよび方法
US7655243B2 (en) 2005-07-22 2010-02-02 The Foundry, Llc Methods and systems for toxin delivery to the nasal cavity
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JP6000851B2 (ja) 2009-11-11 2016-10-05 ホライラ, インコーポレイテッド 組織治療および狭窄制御のためのシステム、装置、および方法
US8911439B2 (en) 2009-11-11 2014-12-16 Holaira, Inc. Non-invasive and minimally invasive denervation methods and systems for performing the same
US9011323B2 (en) * 2010-10-08 2015-04-21 Invuity, Inc. Method and apparatus for soft tissue retraction
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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN114746107A (zh) * 2019-10-10 2022-07-12 梅尔兹治疗有限公司 用于预防人腺体遭受放射损伤的方法

Also Published As

Publication number Publication date
ES2199209T3 (es) 2004-02-16
AR027442A1 (es) 2003-03-26
US6743424B1 (en) 2004-06-01
US6524580B1 (en) 2003-02-25
JP2012207030A (ja) 2012-10-25
WO2001060396A2 (en) 2001-08-23
WO2001060396A3 (en) 2002-03-14
AU2001238369A1 (en) 2001-08-27
US6447785B1 (en) 2002-09-10
US6716427B1 (en) 2004-04-06
JP2003530320A (ja) 2003-10-14
US6740321B1 (en) 2004-05-25
ATE245032T1 (de) 2003-08-15
US6585970B1 (en) 2003-07-01
DE60100473T2 (de) 2004-04-15
DE60100473D1 (de) 2003-08-21
EP1253933A2 (en) 2002-11-06
EP1253933B1 (en) 2003-07-16

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MM4A Annulment or lapse of patent due to non-payment of fees