TWI281396B - Compounds useful for the treatment of diseases - Google Patents

Compounds useful for the treatment of diseases Download PDF

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Publication number
TWI281396B
TWI281396B TW094107960A TW94107960A TWI281396B TW I281396 B TWI281396 B TW I281396B TW 094107960 A TW094107960 A TW 094107960A TW 94107960 A TW94107960 A TW 94107960A TW I281396 B TWI281396 B TW I281396B
Authority
TW
Taiwan
Prior art keywords
phenyl
ethyl
hydroxy
amino
hydroxymethyl
Prior art date
Application number
TW094107960A
Other languages
English (en)
Chinese (zh)
Other versions
TW200534846A (en
Inventor
Alan Daniel Brown
Mark Edward Bunnage
Paul Alan Glossop
Kim James
Charlotte Alice Louise Lane
Original Assignee
Pfizer
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from EP04290725A external-priority patent/EP1577291A1/en
Priority claimed from GB0425064A external-priority patent/GB0425064D0/en
Application filed by Pfizer filed Critical Pfizer
Publication of TW200534846A publication Critical patent/TW200534846A/zh
Application granted granted Critical
Publication of TWI281396B publication Critical patent/TWI281396B/zh

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C237/00—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups
    • C07C237/02—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atoms of the carboxamide groups bound to acyclic carbon atoms of the carbon skeleton
    • C07C237/20—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atoms of the carboxamide groups bound to acyclic carbon atoms of the carbon skeleton the carbon skeleton containing six-membered aromatic rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D217/00—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
    • C07D217/02—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with only hydrogen atoms or radicals containing only carbon and hydrogen atoms, directly attached to carbon atoms of the nitrogen-containing ring; Alkylene-bis-isoquinolines
    • C07D217/06—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with only hydrogen atoms or radicals containing only carbon and hydrogen atoms, directly attached to carbon atoms of the nitrogen-containing ring; Alkylene-bis-isoquinolines with the ring nitrogen atom acylated by carboxylic or carbonic acids, or with sulfur or nitrogen analogues thereof, e.g. carbamates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/16—Amides, e.g. hydroxamic acids
    • A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/06—Antiasthmatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/08—Bronchodilators

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pulmonology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
TW094107960A 2004-03-17 2005-03-16 Compounds useful for the treatment of diseases TWI281396B (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP04290725A EP1577291A1 (en) 2004-03-17 2004-03-17 Phenylethanolamine derivatives as beta-2 agonists
US59179004P 2004-07-27 2004-07-27
GB0425064A GB0425064D0 (en) 2004-11-12 2004-11-12 Compounds useful for the treatment of diseases

Publications (2)

Publication Number Publication Date
TW200534846A TW200534846A (en) 2005-11-01
TWI281396B true TWI281396B (en) 2007-05-21

Family

ID=34961252

Family Applications (1)

Application Number Title Priority Date Filing Date
TW094107960A TWI281396B (en) 2004-03-17 2005-03-16 Compounds useful for the treatment of diseases

Country Status (13)

Country Link
KR (1) KR20070026420A (es)
AP (1) AP2006003743A0 (es)
AR (1) AR048267A1 (es)
EC (1) ECSP066854A (es)
IL (1) IL177754A0 (es)
MA (1) MA28475B1 (es)
NL (1) NL1028559C2 (es)
NO (1) NO20063875L (es)
PA (1) PA8626401A1 (es)
PE (1) PE20060123A1 (es)
SV (1) SV2005002052A (es)
TW (1) TWI281396B (es)
UY (1) UY28810A1 (es)

Also Published As

Publication number Publication date
NL1028559A1 (nl) 2005-09-20
AR048267A1 (es) 2006-04-12
KR20070026420A (ko) 2007-03-08
NO20063875L (no) 2006-09-26
UY28810A1 (es) 2005-10-31
IL177754A0 (en) 2006-12-31
TW200534846A (en) 2005-11-01
MA28475B1 (fr) 2007-03-01
PA8626401A1 (es) 2006-05-16
ECSP066854A (es) 2006-11-24
AP2006003743A0 (en) 2006-10-31
PE20060123A1 (es) 2006-03-08
SV2005002052A (es) 2005-12-13
NL1028559C2 (nl) 2006-04-19

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Legal Events

Date Code Title Description
MM4A Annulment or lapse of patent due to non-payment of fees