TWI233806B - Pharmaceutical composition for treating diabetes by local administration - Google Patents
Pharmaceutical composition for treating diabetes by local administration Download PDFInfo
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- TWI233806B TWI233806B TW090101295A TW90101295A TWI233806B TW I233806 B TWI233806 B TW I233806B TW 090101295 A TW090101295 A TW 090101295A TW 90101295 A TW90101295 A TW 90101295A TW I233806 B TWI233806 B TW I233806B
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- botulinum toxin
- botulinum
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- pharmaceutical composition
- diabetes
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- A61P3/00—Drugs for disorders of the metabolism
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- A—HUMAN NECESSITIES
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- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/48—Drugs for disorders of the endocrine system of the pancreatic hormones
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- A—HUMAN NECESSITIES
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- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
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- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
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- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S424/00—Drug, bio-affecting and body treating compositions
- Y10S424/832—Drug, bio-affecting and body treating compositions involving bacterial toxin that has modified amino acid sequence
Landscapes
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| US09/491,420 US6337075B1 (en) | 2000-01-11 | 2000-01-26 | Methods for treating diabetes |
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| US6261572B1 (en) * | 2000-01-11 | 2001-07-17 | Allergan Sales, Inc. | Method for treating a pancreatic disorder with a neurotoxin |
| US8632785B2 (en) | 2000-02-08 | 2014-01-21 | Allergan, Inc. | Clostridial toxin pharmaceutical composition containing a gelatin fragment |
| US20030118598A1 (en) | 2000-02-08 | 2003-06-26 | Allergan, Inc. | Clostridial toxin pharmaceutical compositions |
| DK1398038T4 (da) * | 2000-02-08 | 2011-03-28 | Allergan Inc | Lægemidler med botulinustoxin |
| US7780967B2 (en) | 2000-02-08 | 2010-08-24 | Allergan, Inc. | Reduced toxicity Clostridial toxin pharmaceutical compositions |
| US6486127B1 (en) * | 2001-05-23 | 2002-11-26 | Insmed, Incorporated | Compositions comprising D-chiro inositol and lipid lowering compounds and methods of treatment thereof |
| US6492339B1 (en) * | 2001-05-23 | 2002-12-10 | Insmed, Incorporated | Compositions comprising D-chiro inositol and sulfonylureas and methods of treatment thereof |
| US6984375B2 (en) * | 2001-08-03 | 2006-01-10 | Allergan, Inc. | Nuclei density and nuclei area methods for determining effects of a botulinum toxin on muscles |
| MXPA04004543A (es) | 2001-11-15 | 2005-03-31 | Micro Algae Corp | Composiciones farmaceuticas que contienen 3,4-propinoperhidropurinas y sus usos para el bloqueo de la transmision neuronal. |
| US20050129677A1 (en) * | 2003-12-10 | 2005-06-16 | Shengwen Li | Lipid rafts and clostridial toxins |
| JP2007538010A (ja) * | 2004-05-07 | 2007-12-27 | ファイトトックス リミテッド | フィコトキシンの経皮投与 |
| JP2007536269A (ja) * | 2004-05-07 | 2007-12-13 | ファイトトックス リミテッド | ゴニオトキシンを用いた創傷の治療方法 |
| US7514088B2 (en) * | 2005-03-15 | 2009-04-07 | Allergan, Inc. | Multivalent Clostridial toxin derivatives and methods of their use |
| US7811584B2 (en) * | 2004-06-30 | 2010-10-12 | Allergan, Inc. | Multivalent clostridial toxins |
| WO2006130161A2 (en) * | 2004-07-21 | 2006-12-07 | The Cornell Research Foundation, Inc. | Therapeutic compounds derived from spider venom and their method of use |
| DE602005011458D1 (de) | 2004-09-01 | 2009-01-15 | Allergan Inc | Abbaubare clostridientoxine |
| AU2006227816B2 (en) | 2005-03-15 | 2012-04-05 | Allergan, Inc. | Modified clostridial toxins with enhanced targeting capabilities for endogenous clostridial toxin receptor systems |
| US8105611B2 (en) * | 2005-06-17 | 2012-01-31 | Allergan, Inc. | Treatment of autoimmune disorder with a neurotoxin |
| WO2009002437A2 (en) * | 2007-06-25 | 2008-12-31 | The Board Of Regents Of The University Of Texas System | Neurotoxin theraphy for postprandial hyperglycemia |
| US8470337B2 (en) * | 2008-03-13 | 2013-06-25 | Allergan, Inc. | Therapeutic treatments using botulinum neurotoxin |
| FR2972928B1 (fr) * | 2011-03-25 | 2013-11-29 | Urgo Lab | Composition contenant une cellulose, une huile vegetale et un solvant volatil, ses utilisations comme pansement |
| US9005628B2 (en) | 2012-10-04 | 2015-04-14 | Dublin City University | Biotherapy for pain |
| GB201312317D0 (en) | 2013-07-09 | 2013-08-21 | Syntaxin Ltd | Cationic neurotoxins |
| US10149893B2 (en) | 2013-09-24 | 2018-12-11 | Allergan, Inc. | Methods for modifying progression of osteoarthritis |
| US9216210B2 (en) | 2013-12-23 | 2015-12-22 | Dublin City University | Multiprotease therapeutics for chronic pain |
| WO2016110662A1 (en) | 2015-01-09 | 2016-07-14 | Ipsen Bioinnovation Limited | Cationic neurotoxins |
| GB201517450D0 (en) | 2015-10-02 | 2015-11-18 | Ipsen Biopharm Ltd | Method |
| GB201607901D0 (en) | 2016-05-05 | 2016-06-22 | Ipsen Biopharm Ltd | Chimeric neurotoxins |
| EP3263710A1 (en) | 2016-07-01 | 2018-01-03 | Ipsen Biopharm Limited | Production of activated clostridial neurotoxins |
| JP7118055B2 (ja) | 2016-09-29 | 2022-08-15 | イプセン バイオファーム リミテッド | ハイブリッド神経毒 |
| EP3758611B1 (en) | 2018-02-26 | 2024-07-24 | Ipsen Biopharm Limited | Ultrasound apparatus to guide injection of non-cytotoxic protease |
| US10960061B1 (en) | 2019-10-18 | 2021-03-30 | Penland Foundation | Treatment of amyotrophic lateral sclerosis using botulinum toxin |
| CA3227431A1 (en) | 2019-10-18 | 2021-04-22 | Penland Foundation | Use of a botulinum toxin for treating autism and/or tolerance to narcotics |
| US11738071B2 (en) | 2021-07-12 | 2023-08-29 | Penland Foundation | Treatment of acute and chronic kidney disease |
| US10967052B1 (en) | 2019-10-18 | 2021-04-06 | Penland Foundation | Treatment of dyslexia using botulinum toxin |
| WO2021231666A1 (en) | 2020-05-15 | 2021-11-18 | Penland Foundation | Treatment of asthma using botulinum toxin |
| US20220143158A1 (en) * | 2020-09-18 | 2022-05-12 | Vanderbilt University | Duodenal administration of botulinum toxin |
| GB202103372D0 (en) | 2021-03-11 | 2021-04-28 | Ipsen Biopharm Ltd | Modified clostridial neurotoxins |
| WO2023287728A1 (en) * | 2021-07-12 | 2023-01-19 | Penland Foundation | Treatment of diabetes and chronic pancreatitis using botulinum toxin |
| GB202318884D0 (en) | 2023-12-11 | 2024-01-24 | Ipsen Biopharm Ltd | Formulation |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB9120306D0 (en) * | 1991-09-24 | 1991-11-06 | Graham Herbert K | Method and compositions for the treatment of cerebral palsy |
| DE69428813T2 (de) | 1993-12-28 | 2002-04-04 | Allergan Sales Inc | Verwendung von Botulinustoxin zur Behandlung von Spannungs-Kopfschmerz |
| US5766605A (en) | 1994-04-15 | 1998-06-16 | Mount Sinai School Of Medicine Of The City University Of New York | Treatment of autonomic nerve dysfunction with botulinum toxin |
| EP0773788B1 (en) | 1995-06-06 | 2003-05-07 | L. Bruce Pearce | Improved compositions and methods for chemodenervation using neurotoxins |
| US6139845A (en) | 1999-12-07 | 2000-10-31 | Allergan Sales, Inc. | Method for treating cancer with a neurotoxin |
| US6337075B1 (en) | 2000-01-11 | 2002-01-08 | Allergan Sales, Inc. | Methods for treating diabetes |
| US6143306A (en) * | 2000-01-11 | 2000-11-07 | Allergan Sales, Inc. | Methods for treating pancreatic disorders |
| US6261572B1 (en) * | 2000-01-11 | 2001-07-17 | Allergan Sales, Inc. | Method for treating a pancreatic disorder with a neurotoxin |
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2000
- 2000-01-26 US US09/491,420 patent/US6337075B1/en not_active Expired - Fee Related
-
2001
- 2001-01-19 TW TW090101295A patent/TWI233806B/zh not_active IP Right Cessation
- 2001-01-24 EP EP01903262A patent/EP1250146B1/en not_active Expired - Lifetime
- 2001-01-24 AU AU2001231104A patent/AU2001231104A1/en not_active Abandoned
- 2001-01-24 ES ES01903262T patent/ES2211765T3/es not_active Expired - Lifetime
- 2001-01-24 DK DK01903262T patent/DK1250146T3/da active
- 2001-01-24 AT AT01903262T patent/ATE257013T1/de not_active IP Right Cessation
- 2001-01-24 DE DE60101669T patent/DE60101669T2/de not_active Expired - Lifetime
- 2001-01-24 JP JP2001554694A patent/JP4851042B2/ja not_active Expired - Lifetime
- 2001-01-24 WO PCT/US2001/002273 patent/WO2001054711A2/en not_active Ceased
- 2001-01-25 AR ARP010100326A patent/AR029464A1/es unknown
- 2001-10-03 US US09/972,702 patent/US6416765B1/en not_active Expired - Lifetime
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|---|---|
| DK1250146T3 (da) | 2004-04-26 |
| ATE257013T1 (de) | 2004-01-15 |
| US6416765B1 (en) | 2002-07-09 |
| WO2001054711A3 (en) | 2002-02-21 |
| EP1250146B1 (en) | 2004-01-02 |
| US6337075B1 (en) | 2002-01-08 |
| WO2001054711A2 (en) | 2001-08-02 |
| US20020031529A1 (en) | 2002-03-14 |
| AU2001231104A1 (en) | 2001-08-07 |
| EP1250146A2 (en) | 2002-10-23 |
| AR029464A1 (es) | 2003-07-02 |
| ES2211765T3 (es) | 2004-07-16 |
| DE60101669D1 (de) | 2004-02-05 |
| JP4851042B2 (ja) | 2012-01-11 |
| JP2003520822A (ja) | 2003-07-08 |
| DE60101669T2 (de) | 2004-10-21 |
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| MM4A | Annulment or lapse of patent due to non-payment of fees |