TW372872B - Thieno[1,5]benzodiazepine use - Google Patents
Thieno[1,5]benzodiazepine useInfo
- Publication number
- TW372872B TW372872B TW084105417A TW84105417A TW372872B TW 372872 B TW372872 B TW 372872B TW 084105417 A TW084105417 A TW 084105417A TW 84105417 A TW84105417 A TW 84105417A TW 372872 B TW372872 B TW 372872B
- Authority
- TW
- Taiwan
- Prior art keywords
- thieno
- benzodiazepine
- methyl
- benzodiazepine use
- piperazinyl
- Prior art date
Links
- YEBHOSNNUQLOLY-UHFFFAOYSA-N 9h-thieno[2,3-i][1,5]benzodiazepine Chemical compound N1=CC=CN=C2C3=CCSC3=CC=C21 YEBHOSNNUQLOLY-UHFFFAOYSA-N 0.000 title 1
- SVUOLADPCWQTTE-UHFFFAOYSA-N 1h-1,2-benzodiazepine Chemical class N1N=CC=CC2=CC=CC=C12 SVUOLADPCWQTTE-UHFFFAOYSA-N 0.000 abstract 1
- 208000018522 Gastrointestinal disease Diseases 0.000 abstract 1
- 239000002253 acid Chemical class 0.000 abstract 1
- 229940049706 benzodiazepine Drugs 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
- A61K31/551—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole having two nitrogen atoms, e.g. dilazep
- A61K31/5513—1,4-Benzodiazepines, e.g. diazepam or clozapine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/12—Antidiarrhoeals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US08/253,658 US5457101A (en) | 1994-06-03 | 1994-06-03 | Thieno[1,5]benzoidiazepine use |
Publications (1)
Publication Number | Publication Date |
---|---|
TW372872B true TW372872B (en) | 1999-11-01 |
Family
ID=22961179
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
TW084105417A TW372872B (en) | 1994-06-03 | 1995-05-29 | Thieno[1,5]benzodiazepine use |
Country Status (14)
Country | Link |
---|---|
US (1) | US5457101A (zh) |
EP (1) | EP0685233B1 (zh) |
JP (1) | JPH07330608A (zh) |
KR (1) | KR960000229A (zh) |
CN (1) | CN1119101A (zh) |
AU (1) | AU684924B2 (zh) |
CA (1) | CA2150517A1 (zh) |
DE (1) | DE69528109D1 (zh) |
HU (1) | HUT71598A (zh) |
IL (1) | IL113912A (zh) |
NO (1) | NO306977B1 (zh) |
NZ (1) | NZ272231A (zh) |
TW (1) | TW372872B (zh) |
ZA (1) | ZA954358B (zh) |
Families Citing this family (43)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CR5278A (es) | 1995-03-24 | 1996-07-04 | Lilly Co Eli | Formulacion oral de 2-metil-tieno-benzodiacepina |
US5631250A (en) * | 1995-03-24 | 1997-05-20 | Eli Lilly And Company | Process and solvate of 2-methyl-thieno-benzodiazepine |
US5637584A (en) * | 1995-03-24 | 1997-06-10 | Eli Lilly And Company | Solvate of olanzapine |
EG23659A (en) * | 1995-03-24 | 2007-03-26 | Lilly Co Eli | Process and crystal forms of methyl-thieno-benzodiazepine |
EG24221A (en) * | 1995-03-24 | 2008-11-10 | Lilly Co Eli | Process for preparing olanzapine |
US5891461A (en) * | 1995-09-14 | 1999-04-06 | Cygnus, Inc. | Transdermal administration of olanzapine |
US5981523A (en) * | 1996-02-05 | 1999-11-09 | Eli Lilly And Company | Compounds and methods for treating multiple sclerosis |
JP2000506860A (ja) * | 1996-03-11 | 2000-06-06 | イーライ・リリー・アンド・カンパニー | 自閉症の処置方法 |
AU734011B2 (en) * | 1996-03-11 | 2001-05-31 | Eli Lilly And Company | Method for treating bipolar disorder |
CN1494907A (zh) * | 1996-03-25 | 2004-05-12 | 治疗疼痛的药物组合物 | |
CN1219878A (zh) * | 1996-03-25 | 1999-06-16 | 伊莱利利公司 | 治疗疼痛的方法 |
IL126063A (en) * | 1996-03-25 | 2002-04-21 | Lilly Co Eli | Medicinal products containing ulanzapine for the treatment of migraine pain |
US5952331A (en) * | 1996-05-23 | 1999-09-14 | Syntex (Usa) Inc. | Aryl pyrimidine derivatives |
US5958934A (en) * | 1996-05-23 | 1999-09-28 | Syntex (U.S.A.) Inc. | Aryl pyrimidine derivatives and uses thereof |
US20030022889A1 (en) * | 1997-04-15 | 2003-01-30 | Bymaster Franklin P. | Method for providing neuro-protective effects |
AU6955998A (en) * | 1997-04-15 | 1998-11-11 | Eli Lilly And Company | Method for providing neuro-protective effects |
JP2002530339A (ja) | 1998-11-23 | 2002-09-17 | セプラコール, インク. | 2−ヒドロキシメチルオランザピン組成物及び方法 |
US6348455B1 (en) | 1998-11-23 | 2002-02-19 | Sepracor Inc. | Desmetylolanzapine compositions and methods |
WO2000030649A1 (en) * | 1998-11-23 | 2000-06-02 | Sepracor Inc. | Pharmaceutical compositions containing olanzapine-n-oxide |
US7022698B2 (en) | 1999-12-28 | 2006-04-04 | U & I Pharmaceuticals, Ltd. | Pharmaceutical compositions containing new polymorphic forms of olanzapine and uses thereof |
US6348458B1 (en) | 1999-12-28 | 2002-02-19 | U & I Pharmaceuticals Ltd. | Polymorphic forms of olanzapine |
US7766013B2 (en) | 2001-06-05 | 2010-08-03 | Alexza Pharmaceuticals, Inc. | Aerosol generating method and device |
US7458374B2 (en) | 2002-05-13 | 2008-12-02 | Alexza Pharmaceuticals, Inc. | Method and apparatus for vaporizing a compound |
US20070122353A1 (en) | 2001-05-24 | 2007-05-31 | Hale Ron L | Drug condensation aerosols and kits |
US7645442B2 (en) | 2001-05-24 | 2010-01-12 | Alexza Pharmaceuticals, Inc. | Rapid-heating drug delivery article and method of use |
UA80095C2 (en) * | 2001-07-20 | 2007-08-27 | Lilly Co Eli | 2 methyl-thieno-benzodiazepine lyophilized formulation and method for the preparation thereof |
GB0203061D0 (en) * | 2002-02-08 | 2002-03-27 | Novartis Ag | Organic compounds |
GB0207091D0 (en) * | 2002-03-26 | 2002-05-08 | Ml Lab Plc | Method of treatment |
US7407788B2 (en) * | 2002-11-21 | 2008-08-05 | Danisco A/S, Genencor Division | BGL7 beta-glucosidase and nucleic acids encoding the same |
US20040105818A1 (en) | 2002-11-26 | 2004-06-03 | Alexza Molecular Delivery Corporation | Diuretic aerosols and methods of making and using them |
US7913688B2 (en) | 2002-11-27 | 2011-03-29 | Alexza Pharmaceuticals, Inc. | Inhalation device for producing a drug aerosol |
EP1625334B9 (en) | 2003-05-21 | 2012-07-25 | Alexza Pharmaceuticals, Inc. | Percussively ignited self-contained heating unit |
GB0314149D0 (en) * | 2003-06-18 | 2003-07-23 | Generics Uk Ltd | Novel amorphous forms |
US20050272720A1 (en) * | 2004-01-27 | 2005-12-08 | Rolf Keltjens | Process for making olanzapine Form I |
WO2005070938A1 (en) * | 2004-01-27 | 2005-08-04 | Synthon B.V. | Stable salts of olanzapine |
US7540286B2 (en) | 2004-06-03 | 2009-06-02 | Alexza Pharmaceuticals, Inc. | Multiple dose condensation aerosol devices and methods of forming condensation aerosols |
EP2353590A1 (en) * | 2005-02-15 | 2011-08-10 | Elan Pharma International Limited | Aerosol and injectable formulations of nanoparticulate benzodiazepine |
WO2007020080A1 (en) * | 2005-08-17 | 2007-02-22 | Synthon B.V. | A process for making olanzapine form i |
WO2007134845A2 (en) * | 2006-05-18 | 2007-11-29 | Synthon B.V. | Olanzapine pharmaceutical composition |
US20080138409A1 (en) * | 2006-09-29 | 2008-06-12 | Osinga Niels J | Olanzapine pharmaceutical composition |
US20080216828A1 (en) | 2007-03-09 | 2008-09-11 | Alexza Pharmaceuticals, Inc. | Heating unit for use in a drug delivery device |
WO2012051502A1 (en) | 2010-10-14 | 2012-04-19 | University Of Utah Research Foundation | Methods and compositions related to neuroactive thiazoline compounds |
EP3497105A1 (en) * | 2016-08-11 | 2019-06-19 | Eli Lilly And Company | Aminothiazines and their use as bace1 inhibitors |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5229382A (en) * | 1990-04-25 | 1993-07-20 | Lilly Industries Limited | 2-methyl-thieno-benzodiazepine |
NZ247703A (en) * | 1992-05-29 | 1995-07-26 | Lilly Industries Ltd | Thienobenzdiazepine derivatives and medicaments thereof |
EP0620222A3 (en) * | 1993-04-14 | 1995-04-12 | Lilly Co Eli | Tetrahydro-beta-carbolines. |
CA2185236A1 (en) * | 1994-03-11 | 1995-09-14 | James Edmund Audia | Method for treating 5ht2b receptor related conditions |
-
1994
- 1994-06-03 US US08/253,658 patent/US5457101A/en not_active Expired - Fee Related
-
1995
- 1995-05-29 TW TW084105417A patent/TW372872B/zh active
- 1995-05-29 ZA ZA954358A patent/ZA954358B/xx unknown
- 1995-05-29 IL IL11391295A patent/IL113912A/xx not_active IP Right Cessation
- 1995-05-29 NZ NZ272231A patent/NZ272231A/en unknown
- 1995-05-30 NO NO952130A patent/NO306977B1/no not_active IP Right Cessation
- 1995-05-30 CA CA002150517A patent/CA2150517A1/en not_active Abandoned
- 1995-05-31 AU AU20424/95A patent/AU684924B2/en not_active Ceased
- 1995-06-01 KR KR1019950014504A patent/KR960000229A/ko not_active Application Discontinuation
- 1995-06-01 CN CN95106142A patent/CN1119101A/zh active Pending
- 1995-06-01 HU HU9501600A patent/HUT71598A/hu unknown
- 1995-06-02 JP JP7136571A patent/JPH07330608A/ja not_active Withdrawn
- 1995-06-02 EP EP95303788A patent/EP0685233B1/en not_active Expired - Lifetime
- 1995-06-02 DE DE69528109T patent/DE69528109D1/de not_active Expired - Lifetime
Also Published As
Publication number | Publication date |
---|---|
NO306977B1 (no) | 2000-01-24 |
DE69528109D1 (de) | 2002-10-17 |
JPH07330608A (ja) | 1995-12-19 |
NZ272231A (en) | 2001-05-25 |
HU9501600D0 (en) | 1995-07-28 |
ZA954358B (en) | 1996-11-29 |
EP0685233A3 (en) | 1996-04-03 |
EP0685233B1 (en) | 2002-09-11 |
IL113912A0 (en) | 1995-08-31 |
AU2042495A (en) | 1995-12-14 |
EP0685233A2 (en) | 1995-12-06 |
IL113912A (en) | 1999-04-11 |
CA2150517A1 (en) | 1995-12-04 |
NO952130D0 (no) | 1995-05-30 |
CN1119101A (zh) | 1996-03-27 |
KR960000229A (ko) | 1996-01-25 |
US5457101A (en) | 1995-10-10 |
NO952130L (no) | 1995-12-04 |
AU684924B2 (en) | 1998-01-08 |
HUT71598A (en) | 1996-01-29 |
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