TW360641B - Novel substituted 7-membered nitrogen ring compounds, their preparation, and their use for the treatment of pain - Google Patents

Novel substituted 7-membered nitrogen ring compounds, their preparation, and their use for the treatment of pain

Info

Publication number
TW360641B
TW360641B TW085115322A TW85115322A TW360641B TW 360641 B TW360641 B TW 360641B TW 085115322 A TW085115322 A TW 085115322A TW 85115322 A TW85115322 A TW 85115322A TW 360641 B TW360641 B TW 360641B
Authority
TW
Taiwan
Prior art keywords
pain
preparation
treatment
membered nitrogen
ring compounds
Prior art date
Application number
TW085115322A
Other languages
English (en)
Chinese (zh)
Inventor
Edward Roberts
Claes Wahlestedt
Original Assignee
Astra Pharma Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Astra Pharma Inc filed Critical Astra Pharma Inc
Application granted granted Critical
Publication of TW360641B publication Critical patent/TW360641B/zh

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D243/00Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms
    • C07D243/06Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4
    • C07D243/08Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4 not condensed with other rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/02Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
    • A61K51/04Organic compounds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/04Centrally acting analgesics, e.g. opioids

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Physics & Mathematics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Neurosurgery (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Pain & Pain Management (AREA)
  • Optics & Photonics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Hydrogenated Pyridines (AREA)
  • Plural Heterocyclic Compounds (AREA)
TW085115322A 1995-12-22 1996-12-11 Novel substituted 7-membered nitrogen ring compounds, their preparation, and their use for the treatment of pain TW360641B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
SE9504662A SE9504662D0 (sv) 1995-12-22 1995-12-22 New compounds

Publications (1)

Publication Number Publication Date
TW360641B true TW360641B (en) 1999-06-11

Family

ID=20400740

Family Applications (1)

Application Number Title Priority Date Filing Date
TW085115322A TW360641B (en) 1995-12-22 1996-12-11 Novel substituted 7-membered nitrogen ring compounds, their preparation, and their use for the treatment of pain

Country Status (21)

Country Link
EP (1) EP0873322A1 (cs)
JP (1) JP2000502680A (cs)
KR (1) KR19990076649A (cs)
CN (1) CN1209126A (cs)
AU (1) AU706436B2 (cs)
BR (1) BR9612206A (cs)
CA (1) CA2239162A1 (cs)
CZ (1) CZ176798A3 (cs)
EE (1) EE9800195A (cs)
HU (1) HUP9900105A3 (cs)
IL (1) IL124997A0 (cs)
IS (1) IS4768A (cs)
NO (1) NO982863L (cs)
NZ (1) NZ324888A (cs)
PL (1) PL327538A1 (cs)
SE (1) SE9504662D0 (cs)
SK (1) SK81998A3 (cs)
TR (1) TR199801184T2 (cs)
TW (1) TW360641B (cs)
WO (1) WO1997023467A1 (cs)
ZA (1) ZA9610355B (cs)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE9504661D0 (sv) * 1995-12-22 1995-12-22 Astra Pharma Inc New compounds
US6441172B1 (en) 1996-11-07 2002-08-27 Torrey Pines Institute For Molecular Studies Diketodiazacyclic compounds, diazacyclic compounds and combinatorial libraries thereof
US7799337B2 (en) 1997-07-21 2010-09-21 Levin Bruce H Method for directed intranasal administration of a composition
GB9804734D0 (en) * 1998-03-05 1998-04-29 Pfizer Ltd Compounds
RU2186295C2 (ru) 1999-10-27 2002-07-27 Беллакем Ою Установка циклического действия для утилизации отходов, содержащих полимерные соединения
EE9900336A (et) 1999-10-27 2000-10-16 Bellakem O� Tsükkeltegevuse seade polümeerühendeid sisaldavate jäätmete utiliseerimiseks
US8473062B2 (en) 2008-05-01 2013-06-25 Autonomic Technologies, Inc. Method and device for the treatment of headache
US8412336B2 (en) 2008-12-29 2013-04-02 Autonomic Technologies, Inc. Integrated delivery and visualization tool for a neuromodulation system
US8494641B2 (en) 2009-04-22 2013-07-23 Autonomic Technologies, Inc. Implantable neurostimulator with integral hermetic electronic enclosure, circuit substrate, monolithic feed-through, lead assembly and anchoring mechanism
US9320908B2 (en) 2009-01-15 2016-04-26 Autonomic Technologies, Inc. Approval per use implanted neurostimulator

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1196150B (it) * 1984-06-19 1988-11-10 Poli Ind Chimica Spa Derivati di 1-(bis-(4-fluorofenil)metil)-4-(3-fenil-2-propenil)-esaidro-1h-1,4-diazepina ad attivita' calcio antagonista,sua preparazione e composizioni che lo contengono
US5028610A (en) * 1987-03-18 1991-07-02 Sankyo Company Limited N-benzhydryl-substituted heterocyclic derivatives, their preparation and their use
US4829065A (en) * 1987-04-24 1989-05-09 Syntex Pharmaceuticals, Ltd. Substituted imidazolyl-alkyl-piperazine and -diazepine derivatives
US4826844A (en) * 1987-09-30 1989-05-02 American Home Products Corporation Substituted 1-(aralkyl-piperazinoalkyl) cycloalkanols
GB9202238D0 (en) * 1992-02-03 1992-03-18 Wellcome Found Compounds
HU221726B1 (hu) * 1993-07-30 2002-12-28 Ardent Pharmaceuticals Inc. Piperazinszármazékok, e vegyületeket tartalmazó gyógyászati készítmények és eljárás a vegyületek előállítására

Also Published As

Publication number Publication date
ZA9610355B (en) 1997-06-23
KR19990076649A (ko) 1999-10-15
NO982863D0 (no) 1998-06-19
CZ176798A3 (cs) 1998-09-16
CN1209126A (zh) 1999-02-24
SK81998A3 (en) 1998-11-04
PL327538A1 (en) 1998-12-21
CA2239162A1 (en) 1997-07-03
JP2000502680A (ja) 2000-03-07
BR9612206A (pt) 1999-07-13
IL124997A0 (en) 1999-01-26
AU1216397A (en) 1997-07-17
EE9800195A (et) 1998-12-15
IS4768A (is) 1998-06-10
TR199801184T2 (xx) 1998-09-21
SE9504662D0 (sv) 1995-12-22
NZ324888A (en) 1999-01-28
WO1997023467A1 (en) 1997-07-03
HUP9900105A2 (hu) 1999-04-28
NO982863L (no) 1998-06-19
AU706436B2 (en) 1999-06-17
EP0873322A1 (en) 1998-10-28
MX9804797A (es) 1998-10-31
HUP9900105A3 (en) 2000-05-29

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