TW268943B - - Google Patents
Info
- Publication number
- TW268943B TW268943B TW082108227A TW82108227A TW268943B TW 268943 B TW268943 B TW 268943B TW 082108227 A TW082108227 A TW 082108227A TW 82108227 A TW82108227 A TW 82108227A TW 268943 B TW268943 B TW 268943B
- Authority
- TW
- Taiwan
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/30—Indoles; Hydrogenated indoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to carbon atoms of the hetero ring
- C07D209/32—Oxygen atoms
- C07D209/34—Oxygen atoms in position 2
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Steroid Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US07/957,152 US5296478A (en) | 1992-10-07 | 1992-10-07 | 1-substituted oxindoles as cognition enhancers |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| TW268943B true TW268943B (OSRAM) | 1996-01-21 |
Family
ID=25499153
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| TW082108227A TW268943B (OSRAM) | 1992-10-07 | 1993-10-05 |
Country Status (7)
| Country | Link |
|---|---|
| US (2) | US5296478A (OSRAM) |
| AU (1) | AU5292893A (OSRAM) |
| IL (1) | IL107177A0 (OSRAM) |
| MX (1) | MX9306234A (OSRAM) |
| TW (1) | TW268943B (OSRAM) |
| WO (1) | WO1994007891A1 (OSRAM) |
| ZA (1) | ZA937453B (OSRAM) |
Families Citing this family (19)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5744476A (en) * | 1994-06-27 | 1998-04-28 | Interneuron Pharmaceuticals, Inc. | Dopamine D1 agonists for the treatment of dementia |
| PT813411E (pt) * | 1995-02-15 | 2002-07-31 | Takeda Chemical Industries Ltd | Utilizacao de derivados de vinpocetina para inibicao da producao ou da secrecao de proteina amiloide beta |
| HRP980429A2 (en) | 1997-08-14 | 1999-06-30 | Jianguo Yin | Crystalline 10,10-bis ((2-fluoro-4-pyridinyl)methyl)-9(10h)-anthracenone and an improved process for preparing the same |
| US20050101929A1 (en) * | 2002-01-17 | 2005-05-12 | Andrew Waksmundzki | Absorbent core with three-dimensional sub-layer |
| MY144968A (en) * | 2005-04-11 | 2011-11-30 | Xenon Pharmaceuticals Inc | Spiro-oxindole compounds and their uses as therapeutic agents |
| AR053710A1 (es) | 2005-04-11 | 2007-05-16 | Xenon Pharmaceuticals Inc | Compuestos espiroheterociclicos y sus usos como agentes terapeuticos |
| AR053713A1 (es) * | 2005-04-20 | 2007-05-16 | Xenon Pharmaceuticals Inc | Compuestos heterociclicos y sus usos como agentes terapeuticos |
| US20080176793A1 (en) * | 2006-09-18 | 2008-07-24 | The Regents Of The University Of California | Upregulating activity or expression of bdnf to mitigate cognitive impairment in asymptomatic huntington's subjects |
| MX2009003876A (es) * | 2006-10-12 | 2009-05-11 | Xenon Pharmaceuticals Inc | Uso de compuestos de espiro-oxindol como agentes terapeuticos. |
| MX2009003875A (es) * | 2006-10-12 | 2009-04-22 | Xenon Pharmaceuticals Inc | Derivados y compuestos relacionados de espiro(furo[3,2-c]piridina- 3,3'-indol)-2' (1'h)ona para el tratamiento de enfermedades mediadas por los canales de sodio, tal como dolor. |
| JP2010522690A (ja) * | 2006-10-12 | 2010-07-08 | ゼノン・ファーマシューティカルズ・インコーポレイテッド | 三環式スピロオキシインドール誘導体および治療薬としてのその使用 |
| PT2350090E (pt) * | 2008-10-17 | 2015-11-13 | Xenon Pharmaceuticals Inc | Composto espiro-oxindol e suas utilizações como agentes terapêuticos |
| WO2010045197A1 (en) * | 2008-10-17 | 2010-04-22 | Xenon Pharmaceuticals, Inc. | Spiro-oxindole compounds and their use as therapeutic agents |
| AR077252A1 (es) | 2009-06-29 | 2011-08-10 | Xenon Pharmaceuticals Inc | Enantiomeros de compuestos de espirooxindol y sus usos como agentes terapeuticos |
| PE20121350A1 (es) | 2009-10-14 | 2012-10-20 | Xenon Pharmaceuticals Inc | Metodos sinteticos para compuestos espiro-oxoindol |
| US20110086899A1 (en) * | 2009-10-14 | 2011-04-14 | Xenon Pharmaceuticals Inc. | Pharmaceutical compositions for oral administration |
| PE20121699A1 (es) | 2010-02-26 | 2012-12-22 | Xenon Pharmaceuticals Inc | Composiciones farmaceuticas del compuesto espiro-oxindol para administracion topica |
| TW201636017A (zh) | 2015-02-05 | 2016-10-16 | 梯瓦製藥國際有限責任公司 | 以螺吲哚酮化合物之局部調配物治療帶狀疱疹後遺神經痛之方法 |
| CN106565683B (zh) * | 2016-09-30 | 2019-03-12 | 江汉大学 | 一种合成3-羟基氧化吲哚衍生物的方法 |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3314954A (en) * | 1964-12-09 | 1967-04-18 | Parke Davis & Co | 1-(diloweralkylamino)-3-(aminoloweralkyl)-3-phenyloxindoles |
| US3595866A (en) * | 1970-01-19 | 1971-07-27 | Parke Davis & Co | 1-amino-3-aminoalkyl-3-phenyloxindole-compounds |
| US4760083A (en) * | 1986-04-10 | 1988-07-26 | E. I. Dupont De Nemours & Company | 3,3-disubstituted indolines |
| US5173489A (en) * | 1986-04-10 | 1992-12-22 | The Dupont Merck Pharmaceutical Co. | α,α-disubstituted aromatics and heteroaromatics as cognition enhancers |
| KR900701784A (ko) * | 1988-06-14 | 1990-12-04 | 스타이너 브이. 캔스타드 | 소염 활성을 갖는 헤테로비사이클릭 화합물 |
| ATE159718T1 (de) * | 1989-07-25 | 1997-11-15 | Taiho Pharmaceutical Co Ltd | Oxoindolderivate |
| US5006537A (en) * | 1989-08-02 | 1991-04-09 | Hoechst-Roussel Pharmaceuticals, Inc. | 1,3-dihydro-1-(pyridinylamino)-2H-indol-2-ones |
| US5278162A (en) * | 1992-09-18 | 1994-01-11 | The Du Pont Merck Pharmaceutical Company | 3,3'-disubstituted-1,3-dihydro-2H-pyrrolo[2,3-b]heterocyclic-2-one useful in the treatment of cognitive disorders of man |
-
1992
- 1992-10-07 US US07/957,152 patent/US5296478A/en not_active Expired - Fee Related
-
1993
- 1993-10-01 AU AU52928/93A patent/AU5292893A/en not_active Abandoned
- 1993-10-01 WO PCT/US1993/009183 patent/WO1994007891A1/en not_active Ceased
- 1993-10-04 IL IL107177A patent/IL107177A0/xx unknown
- 1993-10-05 TW TW082108227A patent/TW268943B/zh active
- 1993-10-06 MX MX9306234A patent/MX9306234A/es unknown
- 1993-10-07 ZA ZA937453A patent/ZA937453B/xx unknown
-
1994
- 1994-02-04 US US08/191,416 patent/US5428035A/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| US5296478A (en) | 1994-03-22 |
| MX9306234A (es) | 1994-05-31 |
| IL107177A0 (en) | 1994-01-25 |
| ZA937453B (en) | 1995-04-07 |
| WO1994007891A1 (en) | 1994-04-14 |
| AU5292893A (en) | 1994-04-26 |
| US5428035A (en) | 1995-06-27 |