TW226996B - Novel isatin and oxindole derivatives which are acetylcholinesterase inhibitors, a process and intermediates for preparing said derivatives and a pharmaceutical composition thereof - Google Patents
Novel isatin and oxindole derivatives which are acetylcholinesterase inhibitors, a process and intermediates for preparing said derivatives and a pharmaceutical composition thereofInfo
- Publication number
- TW226996B TW226996B TW081109950A TW81109950A TW226996B TW 226996 B TW226996 B TW 226996B TW 081109950 A TW081109950 A TW 081109950A TW 81109950 A TW81109950 A TW 81109950A TW 226996 B TW226996 B TW 226996B
- Authority
- TW
- Taiwan
- Prior art keywords
- lower alkyl
- derivatives
- compounds
- intermediates
- hydrogen
- Prior art date
Links
- 239000000543 intermediate Substances 0.000 title abstract 2
- 238000000034 method Methods 0.000 title abstract 2
- 239000008194 pharmaceutical composition Substances 0.000 title abstract 2
- JXDYKVIHCLTXOP-UHFFFAOYSA-N isatin Chemical compound C1=CC=C2C(=O)C(=O)NC2=C1 JXDYKVIHCLTXOP-UHFFFAOYSA-N 0.000 title 2
- 239000000544 cholinesterase inhibitor Substances 0.000 title 1
- 150000005623 oxindoles Chemical class 0.000 title 1
- 125000000217 alkyl group Chemical group 0.000 abstract 6
- 150000001875 compounds Chemical class 0.000 abstract 4
- 229910052739 hydrogen Inorganic materials 0.000 abstract 3
- 239000001257 hydrogen Substances 0.000 abstract 3
- 125000003118 aryl group Chemical group 0.000 abstract 2
- 150000002431 hydrogen Chemical class 0.000 abstract 2
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 abstract 1
- DHKHKXVYLBGOIT-UHFFFAOYSA-N acetaldehyde Diethyl Acetal Natural products CCOC(C)OCC DHKHKXVYLBGOIT-UHFFFAOYSA-N 0.000 abstract 1
- 239000002253 acid Substances 0.000 abstract 1
- 125000003545 alkoxy group Chemical group 0.000 abstract 1
- 125000004104 aryloxy group Chemical group 0.000 abstract 1
- 150000001602 bicycloalkyls Chemical group 0.000 abstract 1
- -1 cyclic acetal Chemical class 0.000 abstract 1
- 125000000392 cycloalkenyl group Chemical group 0.000 abstract 1
- 125000000753 cycloalkyl group Chemical group 0.000 abstract 1
- 229910052736 halogen Inorganic materials 0.000 abstract 1
- 150000002367 halogens Chemical class 0.000 abstract 1
- 125000002887 hydroxy group Chemical group [H]O* 0.000 abstract 1
- 125000000449 nitro group Chemical group [O-][N+](*)=O 0.000 abstract 1
- 230000003287 optical effect Effects 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 239000012453 solvate Substances 0.000 abstract 1
- 125000001424 substituent group Chemical group 0.000 abstract 1
- 230000001225 therapeutic effect Effects 0.000 abstract 1
- 125000002023 trifluoromethyl group Chemical group FC(F)(F)* 0.000 abstract 1
Landscapes
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IN1184DE1992 IN178587B (enrdf_load_stackoverflow) | 1992-12-18 | 1992-12-18 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| TW226996B true TW226996B (en) | 1994-07-21 |
Family
ID=11092503
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| TW081109950A TW226996B (en) | 1992-12-18 | 1992-12-11 | Novel isatin and oxindole derivatives which are acetylcholinesterase inhibitors, a process and intermediates for preparing said derivatives and a pharmaceutical composition thereof |
Country Status (2)
| Country | Link |
|---|---|
| IN (1) | IN178587B (enrdf_load_stackoverflow) |
| TW (1) | TW226996B (enrdf_load_stackoverflow) |
-
1992
- 1992-12-11 TW TW081109950A patent/TW226996B/zh active
- 1992-12-18 IN IN1184DE1992 patent/IN178587B/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| IN178587B (enrdf_load_stackoverflow) | 1997-05-17 |
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