TW224966B - - Google Patents
Info
- Publication number
- TW224966B TW224966B TW082103436A TW82103436A TW224966B TW 224966 B TW224966 B TW 224966B TW 082103436 A TW082103436 A TW 082103436A TW 82103436 A TW82103436 A TW 82103436A TW 224966 B TW224966 B TW 224966B
- Authority
- TW
- Taiwan
- Prior art keywords
- nootropic
- cycloaliphatic
- aliphatic
- denotes
- represents hydrogen
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
- C07F9/6527—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having nitrogen and oxygen atoms as the only ring hetero atoms
- C07F9/653—Five-membered rings
- C07F9/65306—Five-membered rings containing two nitrogen atoms
- C07F9/65318—Five-membered rings containing two nitrogen atoms having the two nitrogen atoms in positions 1 and 3
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/28—Phosphorus compounds with one or more P—C bonds
- C07F9/30—Phosphinic acids [R2P(=O)(OH)]; Thiophosphinic acids ; [R2P(=X1)(X2H) (X1, X2 are each independently O, S or Se)]
- C07F9/301—Acyclic saturated acids which can have further substituents on alkyl
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
- C07F9/553—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having one nitrogen atom as the only ring hetero atom
- C07F9/576—Six-membered rings
- C07F9/58—Pyridine rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
- C07F9/6515—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having three nitrogen atoms as the only ring hetero atoms
- C07F9/6518—Five-membered rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
- C07F9/6524—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having four or more nitrogen atoms as the only ring hetero atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
- C07F9/6527—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having nitrogen and oxygen atoms as the only ring hetero atoms
- C07F9/653—Five-membered rings
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Biochemistry (AREA)
- Molecular Biology (AREA)
- Public Health (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Neurology (AREA)
- Pharmacology & Pharmacy (AREA)
- Biomedical Technology (AREA)
- Animal Behavior & Ethology (AREA)
- Neurosurgery (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Engineering & Computer Science (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Confectionery (AREA)
- Meat, Egg Or Seafood Products (AREA)
- Alcoholic Beverages (AREA)
- Inorganic Compounds Of Heavy Metals (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CH148092 | 1992-05-08 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| TW224966B true TW224966B (enExample) | 1994-06-11 |
Family
ID=4211459
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| TW082103436A TW224966B (enExample) | 1992-05-08 | 1993-05-03 |
Country Status (18)
| Country | Link |
|---|---|
| US (2) | US5332729A (enExample) |
| EP (1) | EP0569333B1 (enExample) |
| JP (1) | JP3243056B2 (enExample) |
| KR (1) | KR940005649A (enExample) |
| AT (1) | ATE175415T1 (enExample) |
| AU (1) | AU662404B2 (enExample) |
| CA (1) | CA2095708C (enExample) |
| DE (1) | DE59309265D1 (enExample) |
| ES (1) | ES2128409T3 (enExample) |
| FI (1) | FI932028L (enExample) |
| GR (1) | GR3029899T3 (enExample) |
| HU (1) | HUT64079A (enExample) |
| IL (1) | IL105628A0 (enExample) |
| NO (1) | NO931675L (enExample) |
| NZ (1) | NZ247561A (enExample) |
| PH (1) | PH30222A (enExample) |
| TW (1) | TW224966B (enExample) |
| ZA (1) | ZA933206B (enExample) |
Families Citing this family (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5457095A (en) * | 1984-10-12 | 1995-10-10 | Ciba-Geigy Corporation | Substituted propane-phosponous acid compounds |
| IL114631A (en) * | 1990-06-22 | 1998-12-06 | Novartis Ag | Anti-epileptic compositions containing gabab- antagonistic compounds |
| EP0543780A3 (en) * | 1991-11-21 | 1993-09-01 | Ciba-Geigy Ag | Novel aminoalkanephosphinic acids and their salts |
| WO1997011953A1 (en) * | 1995-09-28 | 1997-04-03 | Novartis Ag | Novel hydroxylated and alkoxylated n- and/or p-aralkylphosphinic acid derivatives |
| CA2254862A1 (en) * | 1996-05-30 | 1997-12-11 | Novartis Ag | Metabotropic gaba[b] receptors, receptor-specific ligands and their uses |
| US7119189B2 (en) | 1997-03-19 | 2006-10-10 | Novartis Ag | Metabotropic GABA [B] receptors, receptor-specific ligands and their uses |
| GB9906882D0 (en) * | 1999-03-25 | 1999-05-19 | Novartis Ag | Organic compounds |
| US7319095B2 (en) * | 1999-12-09 | 2008-01-15 | Astrazeneca Ab | Use of GABAB receptor agonists |
| SE9904508D0 (sv) * | 1999-12-09 | 1999-12-09 | Astra Ab | New compounds |
| JP4709488B2 (ja) * | 2002-01-18 | 2011-06-22 | メルク・シャープ・エンド・ドーム・コーポレイション | Ｅｄｇ受容体作動薬としてのＮ−（ベンジル）アミノアルキルカルボン酸化合物、ホスフィン酸化合物、ホスホン酸化合物およびテトラゾール類 |
| AR045794A1 (es) * | 2003-09-23 | 2005-11-16 | Aventis Pharma Inc | Procedimiento para preparar derivados de acido 3- amino-2- hidroxipropilfosfinico |
| GB0327186D0 (en) * | 2003-11-21 | 2003-12-24 | Novartis Ag | Organic compounds |
| CA2566204A1 (en) * | 2004-05-14 | 2005-12-01 | The Johns Hopkins University | Method for improving cognitive function by co-administration of a gabab receptor antagonist and an acetylcholinesterase inhibitor |
| US7566738B2 (en) * | 2004-11-03 | 2009-07-28 | Xenoport, Inc. | Acyloxyalkyl carbamate prodrugs of sulfinic acids, methods of synthesis, and use |
| US7494985B2 (en) * | 2004-11-03 | 2009-02-24 | Xenoport, Inc. | Acyloxyalkyl carbamate prodrugs, methods of synthesis, and use |
| US7585996B2 (en) * | 2006-09-15 | 2009-09-08 | Xenoport, Inc. | Acyloxyalkyl carbamate prodrugs, methods of synthesis and use |
Family Cites Families (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3493639A (en) * | 1965-10-27 | 1970-02-03 | Shell Oil Co | Process for producing pentavalent phosphorus derivatives |
| JPS4714129Y1 (enExample) * | 1969-06-11 | 1972-05-22 | ||
| DE2032712C3 (de) * | 1970-07-02 | 1978-10-19 | Bayer Ag, 5090 Leverkusen | Verfahren zur Herstellung von w-Amino-alkanphosphonsäure bzw.- phosphinsäurederivaten |
| DE2440239A1 (de) * | 1974-08-22 | 1976-03-04 | Hoechst Ag | Innere ammoniumsalze von phosphinsaeuren |
| JPS5463024A (en) * | 1977-10-27 | 1979-05-21 | Fujisawa Pharmaceut Co Ltd | 3-(n-formyl-n-hydroxyamino)-2(r)-hydroxypropyl-phosphonic acid, its preparation, and its use |
| EP0093081B1 (de) * | 1982-04-23 | 1986-03-19 | Ciba-Geigy Ag | Herbizide und pflanzenwuchsregulierende Mittel |
| US4536355A (en) * | 1982-10-08 | 1985-08-20 | Zoecon Corporation | Phenoxyphenylaminoalkylphosphinates useful in weed control |
| GB8425872D0 (en) * | 1984-10-12 | 1984-11-21 | Ciba Geigy Ag | Chemical compounds |
| FR2572078B1 (fr) * | 1984-10-24 | 1988-07-15 | Inst Francais Du Petrole | Phosphobetaines neutres, leur preparation et leur application a la recuperation assistee du petrole |
| USD302521S (en) | 1986-03-13 | 1989-08-01 | Grinde James E | Dual compartment container with measurement indicator |
| US5190933A (en) * | 1987-12-04 | 1993-03-02 | Ciba-Geigy Corporation | Substituted propane-phosphinic acid compounds |
| GB8728483D0 (en) * | 1987-12-04 | 1988-01-13 | Ciba Geigy Ag | Chemical compounds |
| GB8820266D0 (en) * | 1988-08-26 | 1988-09-28 | Smith Kline French Lab | Compounds |
| US5212164A (en) * | 1988-08-29 | 1993-05-18 | E. R. Squibb & Sons, Inc. | Phosphorus-containing squalene synthetase inhibitors |
| US5190934A (en) * | 1989-06-03 | 1993-03-02 | Ciba-Geigy Corporation | P-subsituted propane-phosphinic acid compounds |
| IL114631A (en) * | 1990-06-22 | 1998-12-06 | Novartis Ag | Anti-epileptic compositions containing gabab- antagonistic compounds |
| EP0543780A3 (en) * | 1991-11-21 | 1993-09-01 | Ciba-Geigy Ag | Novel aminoalkanephosphinic acids and their salts |
| GB9125615D0 (en) * | 1991-12-02 | 1992-01-29 | Wyeth John & Brother Ltd | Amines |
-
1993
- 1993-04-22 AU AU37112/93A patent/AU662404B2/en not_active Ceased
- 1993-04-29 AT AT93810316T patent/ATE175415T1/de not_active IP Right Cessation
- 1993-04-29 ES ES93810316T patent/ES2128409T3/es not_active Expired - Lifetime
- 1993-04-29 EP EP93810316A patent/EP0569333B1/de not_active Expired - Lifetime
- 1993-04-29 DE DE59309265T patent/DE59309265D1/de not_active Expired - Fee Related
- 1993-05-03 US US08/056,082 patent/US5332729A/en not_active Expired - Lifetime
- 1993-05-03 TW TW082103436A patent/TW224966B/zh active
- 1993-05-05 FI FI932028A patent/FI932028L/fi not_active Application Discontinuation
- 1993-05-06 CA CA002095708A patent/CA2095708C/en not_active Expired - Fee Related
- 1993-05-06 NZ NZ247561A patent/NZ247561A/en unknown
- 1993-05-07 ZA ZA933206A patent/ZA933206B/xx unknown
- 1993-05-07 HU HU9301332A patent/HUT64079A/hu unknown
- 1993-05-07 KR KR1019930007811A patent/KR940005649A/ko not_active Withdrawn
- 1993-05-07 NO NO93931675A patent/NO931675L/no unknown
- 1993-05-07 PH PH46156A patent/PH30222A/en unknown
- 1993-05-07 IL IL105628A patent/IL105628A0/xx unknown
- 1993-05-10 JP JP10789493A patent/JP3243056B2/ja not_active Expired - Fee Related
-
1994
- 1994-05-04 US US08/237,796 patent/US5424441A/en not_active Expired - Lifetime
-
1999
- 1999-04-07 GR GR990400990T patent/GR3029899T3/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| DE59309265D1 (de) | 1999-02-18 |
| EP0569333B1 (de) | 1999-01-07 |
| EP0569333A3 (enExample) | 1994-04-06 |
| AU662404B2 (en) | 1995-08-31 |
| FI932028A7 (fi) | 1993-11-09 |
| CA2095708A1 (en) | 1993-11-09 |
| PH30222A (en) | 1997-02-05 |
| JP3243056B2 (ja) | 2002-01-07 |
| ZA933206B (en) | 1993-11-08 |
| IL105628A0 (en) | 1993-09-22 |
| HU9301332D0 (en) | 1993-09-28 |
| GR3029899T3 (en) | 1999-07-30 |
| HUT64079A (en) | 1993-11-29 |
| ATE175415T1 (de) | 1999-01-15 |
| ES2128409T3 (es) | 1999-05-16 |
| FI932028A0 (fi) | 1993-05-05 |
| CA2095708C (en) | 2005-12-06 |
| AU3711293A (en) | 1993-11-11 |
| KR940005649A (ko) | 1994-03-22 |
| JPH0632793A (ja) | 1994-02-08 |
| US5332729A (en) | 1994-07-26 |
| US5424441A (en) | 1995-06-13 |
| NO931675D0 (no) | 1993-05-07 |
| FI932028L (fi) | 1993-11-09 |
| EP0569333A2 (de) | 1993-11-10 |
| NZ247561A (en) | 1995-07-26 |
| NO931675L (no) | 1993-11-09 |
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