TW202511485A - 調節ｒｐｓ２５基因之表現及／或其功能的反義寡核苷酸 - Google Patents

調節ｒｐｓ２５基因之表現及／或其功能的反義寡核苷酸 Download PDF

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TW202511485A
TW202511485A TW113122108A TW113122108A TW202511485A TW 202511485 A TW202511485 A TW 202511485A TW 113122108 A TW113122108 A TW 113122108A TW 113122108 A TW113122108 A TW 113122108A TW 202511485 A TW202511485 A TW 202511485A
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Taiwan
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antisense oligonucleotide
stranded antisense
nucleic acid
acceptable salt
pharmaceutically acceptable
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TW113122108A
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Chinese (zh)
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青山智彦
浅野成宏
角谷友美
川野邊峻哲
阿賈亞 拉姆 什雷斯塔
鈴木高尾
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日商住友製藥股份有限公司
日商璐庫薩那生物技術股份有限公司
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Publication of TW202511485A publication Critical patent/TW202511485A/zh

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    • A—HUMAN NECESSITIES
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    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/113—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing

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TW113122108A 2023-06-16 2024-06-14 調節ｒｐｓ２５基因之表現及／或其功能的反義寡核苷酸 TW202511485A (zh)

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JP2023099439 2023-06-16
JP2023-099439 2023-06-16

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EP (1) EP4729616A1 (https=)
JP (1) JPWO2024257847A1 (https=)
CN (1) CN121311591A (https=)
TW (1) TW202511485A (https=)
WO (1) WO2024257847A1 (https=)

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP4236812B2 (ja) 1997-09-12 2009-03-11 エクシコン エ／エス オリゴヌクレオチド類似体
CA2778171C (en) 2009-10-29 2017-07-25 Osaka University Bridged artificial nucleoside and nucleotide
KR101707437B1 (ko) 2012-09-21 2017-02-16 고꾸리쯔 다이가꾸 호우징 오사까 다이가꾸 구아니딘 가교를 갖는 인공 뉴클레오시드 및 올리고뉴클레오티드
CN106103463B (zh) 2014-02-18 2018-11-30 国立大学法人大阪大学 桥连型核苷和核苷酸
CN115181778A (zh) 2015-02-04 2022-10-14 百时美施贵宝公司 选择治疗性分子的方法
BR112020008033A2 (pt) 2017-10-23 2020-10-27 Prevail Therapeutics, Inc. terapias gênicas para doença neurodegenerativa
EP3919501A4 (en) 2019-02-01 2022-11-23 Osaka University 5'-MODIFIED NUCLEOSIDE AND NUCLEOTIDE THEREOF
CN116507727A (zh) 2020-11-06 2023-07-28 住友制药株式会社 Rps25基因的表达和/或功能调节剂
US20240247263A1 (en) 2021-05-06 2024-07-25 Luxna Biotech Co., Ltd. Method for designing oligonucleotide having reduced central toxicity

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EP4729616A1 (en) 2026-04-22
JPWO2024257847A1 (https=) 2024-12-19
CN121311591A (zh) 2026-01-09

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