TW202345795A - 純質形式之結晶型阿替卡普蘭 - Google Patents

純質形式之結晶型阿替卡普蘭 Download PDF

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Publication number
TW202345795A
TW202345795A TW112108147A TW112108147A TW202345795A TW 202345795 A TW202345795 A TW 202345795A TW 112108147 A TW112108147 A TW 112108147A TW 112108147 A TW112108147 A TW 112108147A TW 202345795 A TW202345795 A TW 202345795A
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TW
Taiwan
Prior art keywords
composition
atecaplan
treatment
weight
crystalline form
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TW112108147A
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English (en)
Chinese (zh)
Inventor
里卡杜 蘇爾蒙特
馬克 舒米特
維尼納 波帕瓦
亞當 薩維茲
拉瑪 梅爾寇特
偉恩 德瑞維茲
斯里哈里 古帕
達瑞爾 潘柏頓
恰卡拉德哈 萊吉席堤
艾維 凱茲克
Original Assignee
美商健生醫藥公司
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Application filed by 美商健生醫藥公司 filed Critical 美商健生醫藥公司
Publication of TW202345795A publication Critical patent/TW202345795A/zh

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    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D207/00Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/04Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D207/06Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with radicals, containing only hydrogen and carbon atoms, attached to ring carbon atoms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/24Antidepressants
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07BGENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B2200/00Indexing scheme relating to specific properties of organic compounds
    • C07B2200/13Crystalline forms, e.g. polymorphs

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Neurology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Psychiatry (AREA)
  • Pain & Pain Management (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
TW112108147A 2022-03-07 2023-03-06 純質形式之結晶型阿替卡普蘭 TW202345795A (zh)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US202263317483P 2022-03-07 2022-03-07
US63/317,483 2022-03-07

Publications (1)

Publication Number Publication Date
TW202345795A true TW202345795A (zh) 2023-12-01

Family

ID=85979414

Family Applications (1)

Application Number Title Priority Date Filing Date
TW112108147A TW202345795A (zh) 2022-03-07 2023-03-06 純質形式之結晶型阿替卡普蘭

Country Status (15)

Country Link
US (2) US20230348377A1 (https=)
EP (1) EP4489748A1 (https=)
JP (1) JP2025508071A (https=)
KR (1) KR20240158951A (https=)
CN (1) CN119156210A (https=)
AU (1) AU2023231493A1 (https=)
CA (1) CA3254503A1 (https=)
CL (1) CL2024002643A1 (https=)
CO (1) CO2024012457A2 (https=)
IL (1) IL315411A (https=)
JO (1) JOP20240195A1 (https=)
MX (1) MX2024010978A (https=)
PE (1) PE20242109A1 (https=)
TW (1) TW202345795A (https=)
WO (1) WO2023170547A1 (https=)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US12161622B2 (en) 2021-05-04 2024-12-10 Janssen Pharmaceuticals, Inc. Compositions and methods for the treatment of depression
WO2023170554A1 (en) 2022-03-07 2023-09-14 Janssen Pharmaceuticals, Inc. Compositions comprising aticaprant
WO2023170550A1 (en) 2022-03-07 2023-09-14 Janssen Pharmaceuticals, Inc. Polymorph forms of aticaprant for use in treating major depressive disorder
CN117903050B (zh) * 2024-03-15 2024-05-17 中国药科大学 阿立哌唑共晶及其药物组合物和应用

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP5345637B2 (ja) * 2008-01-22 2013-11-20 イーライ リリー アンド カンパニー κ選択的オピオイド受容体アンタゴニスト
US10316021B2 (en) * 2016-11-28 2019-06-11 Pfizer Inc. Heteroarylphenoxy benzamide kappa opioid ligands
PH12023552963A1 (en) * 2021-05-04 2024-03-11 Janssen Pharmaceuticals Inc Compositions and methods for the treatment of depression

Also Published As

Publication number Publication date
KR20240158951A (ko) 2024-11-05
EP4489748A1 (en) 2025-01-15
JOP20240195A1 (ar) 2024-09-05
JP2025508071A (ja) 2025-03-21
CL2024002643A1 (es) 2025-01-24
AU2023231493A1 (en) 2024-10-24
US20250326714A1 (en) 2025-10-23
WO2023170547A1 (en) 2023-09-14
MX2024010978A (es) 2024-12-06
CN119156210A (zh) 2024-12-17
CO2024012457A2 (es) 2024-09-30
PE20242109A1 (es) 2024-10-28
IL315411A (en) 2024-11-01
CA3254503A1 (en) 2023-09-14
US20230348377A1 (en) 2023-11-02

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