JOP20240195A1 - أشكال نقية من أتيكابرانت البلوري - Google Patents

أشكال نقية من أتيكابرانت البلوري

Info

Publication number
JOP20240195A1
JOP20240195A1 JOJO/P/2024/0195A JOP20240195A JOP20240195A1 JO P20240195 A1 JOP20240195 A1 JO P20240195A1 JO P20240195 A JOP20240195 A JO P20240195A JO P20240195 A1 JOP20240195 A1 JO P20240195A1
Authority
JO
Jordan
Prior art keywords
aticabrant
crystalline
pure forms
aticaprant
solvates
Prior art date
Application number
JOJO/P/2024/0195A
Other languages
Arabic (ar)
English (en)
Inventor
Darrel Pemberton
Srihari Gopal
Adam Savitz
Riccardo Surmont
Mark Schmidt
Chakradhar Lagishetty
Rama Melkote
Vanina Popova
Iva Kezic
Wayne C Drevets
Original Assignee
Janssen Pharmaceuticals Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Janssen Pharmaceuticals Inc filed Critical Janssen Pharmaceuticals Inc
Publication of JOP20240195A1 publication Critical patent/JOP20240195A1/ar

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/24Antidepressants
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D207/00Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/04Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D207/06Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with radicals, containing only hydrogen and carbon atoms, attached to ring carbon atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07BGENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B2200/00Indexing scheme relating to specific properties of organic compounds
    • C07B2200/13Crystalline forms, e.g. polymorphs

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Neurology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Psychiatry (AREA)
  • Pain & Pain Management (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
JOJO/P/2024/0195A 2022-03-07 2024-09-05 أشكال نقية من أتيكابرانت البلوري JOP20240195A1 (ar)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US202263317483P 2022-03-07 2022-03-07
PCT/IB2023/052082 WO2023170547A1 (en) 2022-03-07 2023-03-06 Pure forms of crystalline aticaprant

Publications (1)

Publication Number Publication Date
JOP20240195A1 true JOP20240195A1 (ar) 2024-09-05

Family

ID=85979414

Family Applications (1)

Application Number Title Priority Date Filing Date
JOJO/P/2024/0195A JOP20240195A1 (ar) 2022-03-07 2024-09-05 أشكال نقية من أتيكابرانت البلوري

Country Status (15)

Country Link
US (2) US20230348377A1 (https=)
EP (1) EP4489748A1 (https=)
JP (1) JP2025508071A (https=)
KR (1) KR20240158951A (https=)
CN (1) CN119156210A (https=)
AU (1) AU2023231493A1 (https=)
CA (1) CA3254503A1 (https=)
CL (1) CL2024002643A1 (https=)
CO (1) CO2024012457A2 (https=)
IL (1) IL315411A (https=)
JO (1) JOP20240195A1 (https=)
MX (1) MX2024010978A (https=)
PE (1) PE20242109A1 (https=)
TW (1) TW202345795A (https=)
WO (1) WO2023170547A1 (https=)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US12161622B2 (en) 2021-05-04 2024-12-10 Janssen Pharmaceuticals, Inc. Compositions and methods for the treatment of depression
WO2023170554A1 (en) 2022-03-07 2023-09-14 Janssen Pharmaceuticals, Inc. Compositions comprising aticaprant
WO2023170550A1 (en) 2022-03-07 2023-09-14 Janssen Pharmaceuticals, Inc. Polymorph forms of aticaprant for use in treating major depressive disorder
CN117903050B (zh) * 2024-03-15 2024-05-17 中国药科大学 阿立哌唑共晶及其药物组合物和应用

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP5345637B2 (ja) * 2008-01-22 2013-11-20 イーライ リリー アンド カンパニー κ選択的オピオイド受容体アンタゴニスト
US10316021B2 (en) * 2016-11-28 2019-06-11 Pfizer Inc. Heteroarylphenoxy benzamide kappa opioid ligands
PH12023552963A1 (en) * 2021-05-04 2024-03-11 Janssen Pharmaceuticals Inc Compositions and methods for the treatment of depression

Also Published As

Publication number Publication date
KR20240158951A (ko) 2024-11-05
EP4489748A1 (en) 2025-01-15
JP2025508071A (ja) 2025-03-21
CL2024002643A1 (es) 2025-01-24
AU2023231493A1 (en) 2024-10-24
TW202345795A (zh) 2023-12-01
US20250326714A1 (en) 2025-10-23
WO2023170547A1 (en) 2023-09-14
MX2024010978A (es) 2024-12-06
CN119156210A (zh) 2024-12-17
CO2024012457A2 (es) 2024-09-30
PE20242109A1 (es) 2024-10-28
IL315411A (en) 2024-11-01
CA3254503A1 (en) 2023-09-14
US20230348377A1 (en) 2023-11-02

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