KR20240158951A - 결정질 아티카프란트의 순수한 형태 - Google Patents

결정질 아티카프란트의 순수한 형태 Download PDF

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Publication number
KR20240158951A
KR20240158951A KR1020247033036A KR20247033036A KR20240158951A KR 20240158951 A KR20240158951 A KR 20240158951A KR 1020247033036 A KR1020247033036 A KR 1020247033036A KR 20247033036 A KR20247033036 A KR 20247033036A KR 20240158951 A KR20240158951 A KR 20240158951A
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KR
South Korea
Prior art keywords
articaprant
composition
crystalline form
chemically
enantiomerically pure
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
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KR1020247033036A
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English (en)
Korean (ko)
Inventor
리카르도 서몬트
마크 쉬밋
바니나 포포바
아담 사비츠
라마 멜코트
웨인 씨. 드레베츠
스리하리 고팔
데럴 펨버톤
차크라다르 라기셰티
아이바 케직
Original Assignee
얀센 파마슈티칼즈, 인코포레이티드
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
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Application filed by 얀센 파마슈티칼즈, 인코포레이티드 filed Critical 얀센 파마슈티칼즈, 인코포레이티드
Publication of KR20240158951A publication Critical patent/KR20240158951A/ko
Pending legal-status Critical Current

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/04—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D207/06—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with radicals, containing only hydrogen and carbon atoms, attached to ring carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B2200/00—Indexing scheme relating to specific properties of organic compounds
    • C07B2200/13—Crystalline forms, e.g. polymorphs

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Neurology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Psychiatry (AREA)
  • Pain & Pain Management (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
KR1020247033036A 2022-03-07 2023-03-06 결정질 아티카프란트의 순수한 형태 Pending KR20240158951A (ko)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US202263317483P 2022-03-07 2022-03-07
US63/317,483 2022-03-07
PCT/IB2023/052082 WO2023170547A1 (en) 2022-03-07 2023-03-06 Pure forms of crystalline aticaprant

Publications (1)

Publication Number Publication Date
KR20240158951A true KR20240158951A (ko) 2024-11-05

Family

ID=85979414

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1020247033036A Pending KR20240158951A (ko) 2022-03-07 2023-03-06 결정질 아티카프란트의 순수한 형태

Country Status (15)

Country Link
US (2) US20230348377A1 (https=)
EP (1) EP4489748A1 (https=)
JP (1) JP2025508071A (https=)
KR (1) KR20240158951A (https=)
CN (1) CN119156210A (https=)
AU (1) AU2023231493A1 (https=)
CA (1) CA3254503A1 (https=)
CL (1) CL2024002643A1 (https=)
CO (1) CO2024012457A2 (https=)
IL (1) IL315411A (https=)
JO (1) JOP20240195A1 (https=)
MX (1) MX2024010978A (https=)
PE (1) PE20242109A1 (https=)
TW (1) TW202345795A (https=)
WO (1) WO2023170547A1 (https=)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US12161622B2 (en) 2021-05-04 2024-12-10 Janssen Pharmaceuticals, Inc. Compositions and methods for the treatment of depression
WO2023170554A1 (en) 2022-03-07 2023-09-14 Janssen Pharmaceuticals, Inc. Compositions comprising aticaprant
WO2023170550A1 (en) 2022-03-07 2023-09-14 Janssen Pharmaceuticals, Inc. Polymorph forms of aticaprant for use in treating major depressive disorder
CN117903050B (zh) * 2024-03-15 2024-05-17 中国药科大学 阿立哌唑共晶及其药物组合物和应用

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP5345637B2 (ja) * 2008-01-22 2013-11-20 イーライ リリー アンド カンパニー κ選択的オピオイド受容体アンタゴニスト
US10316021B2 (en) * 2016-11-28 2019-06-11 Pfizer Inc. Heteroarylphenoxy benzamide kappa opioid ligands
PH12023552963A1 (en) * 2021-05-04 2024-03-11 Janssen Pharmaceuticals Inc Compositions and methods for the treatment of depression

Also Published As

Publication number Publication date
EP4489748A1 (en) 2025-01-15
JOP20240195A1 (ar) 2024-09-05
JP2025508071A (ja) 2025-03-21
CL2024002643A1 (es) 2025-01-24
AU2023231493A1 (en) 2024-10-24
TW202345795A (zh) 2023-12-01
US20250326714A1 (en) 2025-10-23
WO2023170547A1 (en) 2023-09-14
MX2024010978A (es) 2024-12-06
CN119156210A (zh) 2024-12-17
CO2024012457A2 (es) 2024-09-30
PE20242109A1 (es) 2024-10-28
IL315411A (en) 2024-11-01
CA3254503A1 (en) 2023-09-14
US20230348377A1 (en) 2023-11-02

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