TW202330009A - Topical skin whitening composite liquid which can effectively whiten the skin and sustain the effect and will not stimulate the skin - Google Patents
Topical skin whitening composite liquid which can effectively whiten the skin and sustain the effect and will not stimulate the skin Download PDFInfo
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Abstract
Description
本發明與皮膚保養品有關，特別是指一種外用皮膚美白複合液。The invention relates to skin care products, in particular to an external skin whitening compound solution.
斑點、暗沈、皮膚鬆弛等是困擾很多愛美人士的問題，隨著年齡的增長，皮膚的膠原蛋白逐漸流失，皮膚細胞的再生能力也慢慢下降，隨之而來的是皺紋的增長與色素的沈積。Spots, dullness, and sagging skin are problems that plague many beauty lovers. With age, the collagen in the skin is gradually lost, and the regeneration ability of skin cells is also slowly declining, followed by the growth of wrinkles and pigmentation. deposition.
目前市面上有許多具有抗斑、美白、保濕以及除皺作用的美容護膚品，也有一些通過先進設備的治療手段應運而生，但是仍然難以達到令人滿意的效果。一些美容護膚品含有大量的化學合成物質，長期使用不但不能解決肌膚的問題，還會增加肌膚的負擔或引發過敏反應。例如，大多數的護膚品主要以化學抗衰老因子發揮作用，在抗衰老的同時會帶來一些副作用，長期使用反而刺激皮膚，導致皮膚易過敏、吸收差、油膩等問題。以雷射去斑、注射玻尿酸等是近年來運用比較多的技術，雖然在短時期內有立竿見影的效果，但效果難以維持，而且治療費用高昂，不利推廣使用。There are many beauty and skin care products with anti-spot, whitening, moisturizing and wrinkle-removing effects on the market, and some treatments with advanced equipment have emerged at the historic moment, but it is still difficult to achieve satisfactory results. Some beauty and skin care products contain a lot of chemical synthetic substances. Long-term use will not only fail to solve skin problems, but will also increase the burden on the skin or cause allergic reactions. For example, most skin care products mainly use chemical anti-aging factors, which will cause some side effects while anti-aging. Long-term use will irritate the skin, leading to skin allergies, poor absorption, greasy and other problems. Laser speckle removal and hyaluronic acid injection have been widely used in recent years. Although there are immediate results in a short period of time, the results are difficult to maintain, and the treatment costs are high, which is not conducive to popularization.
本發明之一目的在於提供一種外用皮膚美白複合液，可有效美白肌膚，效果持續且不會刺激皮膚。One object of the present invention is to provide an external skin whitening complex liquid, which can effectively whiten the skin, and the effect is sustained without irritating the skin.
為了達成上述目的，本發明之外用皮膚美白複合液包含有10 wt%的海椰子(Seychelles Nut)、8 wt%的黑綿羊胎盤(Ovine Placenta)、5 wt%的聖潔莓(Chasteberry)、以及餘量的水。藉此，該外用皮膚美白複合液可有效美白肌膚，效果持續且不會刺激皮膚。In order to achieve the above-mentioned purpose, the skin whitening complex solution used in addition to the present invention contains 10 wt% Seychelles Nut, 8 wt% Ovine Placenta, 5 wt% Chasteberry, and remaining amount of water. Thereby, the skin whitening compound solution for external use can effectively whiten the skin, the effect is sustained and the skin will not be irritated.
以下藉由一較佳實施例詳細說明本發明的技術內容及特徵，本發明一較佳實施例所提供之外用皮膚美白複合液，包含有10 wt%的海椰子(Seychelles Nut)、8 wt%的黑綿羊胎盤(Ovine Placenta)、5 wt%的聖潔莓(Chasteberry)、3 wt%的傳明酸(Tranexamic Acid)、5 wt%的α熊果素(α Arbutin)、5 wt%的桑白皮(Sangbaipi)、3 wt%的木瓜酵素(Papain Enzyme)、1 wt%的奈米珍珠液(Nanometer Pearl)、3 wt%的彈力蛋白(Elastin)、2 wt%的维生素C糖苷(Ascorbyl Glucoside)、5 wt%的白芷(Angelica Dahurica)以及50%的水。The technical contents and characteristics of the present invention are described in detail below by means of a preferred embodiment. The skin whitening complex liquid for external use provided by a preferred embodiment of the present invention includes 10 wt% Seychelles Nut, 8 wt% Black sheep placenta (Ovine Placenta), 5 wt% chasteberry (Chasteberry), 3 wt% tranexamic acid (Tranexamic Acid), 5 wt% α arbutin (α Arbutin), 5 wt% Morus alba ( Sangbaipi), 3 wt% of papain enzyme (Papain Enzyme), 1 wt% of nano pearl liquid (Nanometer Pearl), 3 wt% of elastin (Elastin), 2 wt% of vitamin C glycoside (Ascorbyl Glucoside), 5 wt% Angelica Dahurica and 50% water.
海椰子的學名為Lodoicea maldivica，別名海底椰、白玉丹、白律丹、綠巨人，屬棕櫚科(Arecaceae)，是一種透明的萃取液。海椰子含有大量的蛋白質和氨基酸，可以讓肌肉變得強壯、皮膚變得光澤，而且有彈性可以改善皮膚的色斑和暗沉的狀況，還可以美白皮膚。以3~10 wt%用量進行為期八周的人體實驗，針對20位20到45歲，中度至重度肌膚因歲月而缺乏彈性、鬆弛、肌膚細胞老化的民眾，臨床實驗後發現，有36%的受測者表示其肌膚的暗沉獲得改善，47%提升肌膚亮澤度，55%改善歲月所造成的肌膚損害，63%改善肌膚緊實與恢復肌膚彈性，還有77%表示粗糙、乾燥的肌膚獲得改善。The scientific name of sea coconut is Lodoicea maldivica, also known as Sea Coconut, Baiyudan, Bailudan, Hulk, belonging to the palm family (Arecaceae), and it is a transparent extract. Sea coconut contains a lot of protein and amino acids, which can make the muscles strong and the skin shiny, and its elasticity can improve the skin's pigmentation and dullness, and it can also whiten the skin. An eight-week human experiment was carried out at a dosage of 3~10 wt%. Aiming at 20 people aged 20 to 45 with moderate to severe skin loss due to aging, sagging, and aging skin cells, it was found after the clinical experiment that 36% 47% of the subjects said that their skin dullness has been improved, 47% have improved skin radiance, 55% have improved skin damage caused by aging, 63% have improved skin firmness and restored skin elasticity, and 77% have expressed roughness and dryness skin is improved.
黑綿羊胎盤是一種淡黃色的萃取液，黑綿羊胎盤萃取液可以加強皮膚淨白保濕，修復避免肌膚變老變黑的成分，並且可使皮膚加強有效吸收，使色素自然脫落，加速肌膚的新陳代謝。以2~8 wt%用量進行為期八周的人體實驗，針對20位20到48歲，中度至重度膚色偏黑、有乾燥性皮膚的民眾，臨床實驗後發現，有47%提升肌膚亮澤度，55%改善肌膚暗沉的狀況，63%改善膚色偏黑，還有77%表示粗糙、乾燥的皮膚獲得改善。Black sheep placenta is a light yellow extract. Black sheep placenta extract can strengthen skin whitening and moisturizing, repair ingredients that prevent skin from aging and darkening, and can enhance effective skin absorption, make pigment naturally fall off, and accelerate skin metabolism. . An eight-week human experiment was carried out at a dosage of 2~8 wt%. Aiming at 20 people aged 20 to 48, with moderate to severe dark complexion and dry skin, it was found after the clinical experiment that 47% of them improved skin radiance 55% improved dull skin, 63% improved dark skin tone, and 77% said rough and dry skin was improved.
聖潔莓的學名為Vitex negundo L.，別名牡荊、埔姜、七葉埔姜、黃肉埔姜、不驚茶，是一種米黃色的萃取液，屬馬鞭草科，聖潔莓包含了一些不同的醫療成分，臨床研究報告顯示聖潔莓能平衡雌激素以及植物性女性荷爾蒙的濃度，影響腦下腺和下視丘，幫助正常化產生雌激素。以4~8 wt%用量進行為期八周的人體實驗，針對20位20到45歲，中度至重度肌膚因歲月而缺乏彈性、鬆弛、肌膚細胞老化的民眾，臨床實驗後發現，有36%的受測者表示其肌膚的暗沉獲得改善，47%提升肌膚亮澤度，55%改善歲月所造成的肌膚損害，63%改善肌膚緊實與恢復肌膚彈性，還有77%表示粗糙、乾燥的肌膚獲得改善。The scientific name of chaste berry is Vitex negundo L., also known as Vitex negundo L., alias vitex, Pujiang, Qiyepu ginger, Huangroupu ginger, Bujing tea. It is a beige extract, which belongs to Verbenaceae. Chaste berry contains some Different medical ingredients, clinical research reports show that chaste berry can balance the concentration of estrogen and phytoestrogens, affect the hypothalamus and hypothalamus, and help normalize the production of estrogen. An eight-week human experiment was carried out at a dosage of 4-8 wt%. Aiming at 20 people aged 20 to 45, with moderate to severe skin loss due to age, relaxation, and skin cell aging, it was found after clinical trials that 36% 47% of the subjects said that their skin dullness has been improved, 47% have improved skin radiance, 55% have improved skin damage caused by aging, 63% have improved skin firmness and restored skin elasticity, and 77% have expressed roughness and dryness skin is improved.
傳明酸是一種淡黃色的原液，兼具有保濕、抗氧化、促進血液循環、消炎的效果，能深入肌膚內部抑制黑色素生成並促進新陳代謝，同時能消炎保濕賦活改善紫外線傷害所產生的粗糙，使肌膚更明亮具有光澤，還能預防黑斑雀斑形成，達到最佳的美白效果。以3~8 wt%用量進行為期八周的人體實驗，針對20位15到40歲，中度至重度皮膚偏黑、暗沉、無光彩、乾燥肌膚的民眾，臨床實驗後發現，有36%的受測者表示其老化的肌膚獲得改善，47%提升肌膚亮澤度，55%改善暗沉的肌膚，63%改善黑肌膚的狀況，還有77%表示粗糙、乾燥的肌膚獲得改善。Tranexamic acid is a light yellow stock solution, which has the effects of moisturizing, anti-oxidation, promoting blood circulation, and anti-inflammation. It can penetrate deep into the skin to inhibit melanin production and promote metabolism. Make the skin brighter and more lustrous, prevent the formation of dark spots and freckles, and achieve the best whitening effect. An eight-week human experiment was carried out at a dosage of 3~8 wt%, targeting 20 people aged 15 to 40 with moderate to severe skin darkening, dull, dull, and dry skin. After clinical trials, it was found that 36% 47% of subjects said their aging skin improved, 47% improved skin radiance, 55% improved dull skin, 63% improved dark skin conditions, and 77% said rough, dry skin improved.
α熊果素是一種透明的萃取液，是超強的淡斑美白成分，除了沒有不舒服的氣味和副作用外，也能有效地美白皮膚，主要的作用有三項：美白、年輕肌膚以及抵抗紫外線的傷害。以1~5 wt%用量進行為期八周的人體實驗，針對20位15到40歲，中度至重度皮膚偏黑、肌膚暗沉的民眾，臨床實驗後發現，有74%的受測者表示提升肌膚亮澤度，75%改善暗沉的肌膚，83%改善膚色偏黑的狀況，還有79%表示粗糙、乾燥的肌膚獲得改善。α-Arbutin is a kind of transparent extract, which is a powerful lightening and whitening ingredient. In addition to having no unpleasant smell and side effects, it can also effectively whiten the skin. There are three main functions: whitening, youthful skin and resistance to UV damage . An eight-week human experiment was carried out at a dosage of 1~5 wt%. Aiming at 20 people aged 15 to 40 with moderate to severe dark skin and dull skin, it was found after the clinical experiment that 74% of the subjects said that Improve skin radiance, 75% improved dull skin, 83% improved dark complexion, and 79% said rough and dry skin was improved.
桑白皮別名娘仔葉樹、潭仔葉，是一種赤黃色的萃取液，能幫助肌膚達到嫩白、消炎、保濕的功能，並且能夠有效地預防肌膚的暗沉，以及肌膚的敏感，能進一步阻斷黑色素的合成，不讓黑色素有成形的機會，故美白的效果能夠有效達成，並且穩定性良好，能幫助肌膚有良好的吸收達到很好的效果，並且能讓肌膚與細胞有時間能恢復到很好的狀況。以5~10 wt%用量進行為期八周的人體實驗，針對20位20到45歲，中度至重度暗沉肌膚的民眾，臨床實驗後發現，有69%的受測者表示其肌膚的暗沉獲得改善，76%的受測者表示提升肌膚亮澤度，85%改善歲月所造成的肌膚損害，82%改善肌膚緊實與恢復肌膚彈性，還有74%表示粗糙、乾燥的肌膚獲得改善。Morus alba, also known as Niangzai Yeshu and Tanzai Ye, is a reddish-yellow extract that can help the skin achieve whitening, anti-inflammatory, and moisturizing functions, and can effectively prevent skin dullness and skin sensitivity. Further block the synthesis of melanin and prevent melanin from forming, so the whitening effect can be effectively achieved, and the stability is good, it can help the skin to absorb well to achieve a good effect, and it can give the skin and cells time to recover Restored to great condition. An eight-week human experiment was carried out at a dosage of 5-10 wt%. Aiming at 20 people aged 20 to 45 with moderate to severe dull skin, it was found after the clinical experiment that 69% of the subjects said their skin was dark. Shen was improved, 76% of the subjects said that the skin radiance was improved, 85% improved the skin damage caused by aging, 82% improved skin firmness and restored skin elasticity, and 74% said that rough and dry skin was improved .
木瓜酵素是一種淡黃色的原液，能加強毛孔的暢通，可以去除老廢角質達到角質更新的作用，也能減少粉刺和痘痘的增加，常被使用作為去角質方面的產品，效果極佳，使用後觸感溫和，能補充肌膚天然養分或活化細胞，使皮膚立刻增加彈性和光澤。以3~6 wt%用量進行為期八周的人體實驗，針對20位15到30歲，中度至重度肌膚有毛孔過大、粉刺過多、角質層過厚的民眾，臨床實驗後發現，有75%的受測者表示有改善毛孔過大、粉刺過多的肌膚，68%有提高肌膚的彈性與光澤，86%改善肌膚角質層過厚，還有84%表示粗糙、乾燥的肌膚獲得改善。Papaya enzyme is a kind of light yellow stock solution, which can strengthen the unblocking of pores, remove old waste cutin to achieve the effect of cutin renewal, and also reduce the increase of acne and acne. It is often used as an exfoliating product, and the effect is excellent. It is mild to the touch after use, can replenish the skin's natural nutrients or activate cells, and immediately increase the elasticity and luster of the skin. An eight-week human experiment was carried out at a dosage of 3~6 wt%, targeting 20 people aged 15 to 30 with moderate to severe skin with excessively large pores, excessive acne, and excessively thick stratum corneum. After clinical trials, it was found that 75% 68% of the subjects said that it improved the skin with excessive pores and acne, 68% improved the elasticity and luster of the skin, 86% improved the thick cuticle of the skin, and 84% said that the rough and dry skin was improved.
奈米珍珠液是一種透明的原液，含有豐富的高級脂肪醇，易被人體表皮細胞吸收，可增強細胞活力，促進細胞新陳代謝，並且奈米珍珠液能促進人體膠原細胞生長，當有外傷、創口時，能促進膠原細胞生長填補空隙、連接組織，促使肌膚再生，保持肌膚柔嫩潤白，光滑完整。以0.5~1 wt%用量進行為期八周的人體實驗，針對20位16到35歲，中度至重度肌膚細胞老化、皮膚乾燥、肌膚缺乏水分的民眾，臨床實驗後發現，有77%的受測者表示提升肌膚亮澤度，85%改善肌膚老化的細胞，83%粗糙、乾燥的肌膚獲得改善，還有72%表示皮膚保有水分。Nano-pearl liquid is a transparent stock solution, rich in high-grade fatty alcohols, easily absorbed by human epidermal cells, can enhance cell vitality, promote cell metabolism, and nano-pearl liquid can promote the growth of human collagen cells, when there is trauma, wound When used, it can promote the growth of collagen cells to fill gaps, connect tissues, promote skin regeneration, and keep skin soft, white, smooth and complete. An eight-week human experiment was carried out at a dosage of 0.5~1 wt%, targeting 20 people aged 16 to 35 with moderate to severe skin cell aging, dry skin, and lack of moisture in the skin. After the clinical experiment, it was found that 77% of the people affected The testers said that the skin's radiance was improved, 85% of the skin's aging cells were improved, 83% of the rough and dry skin were improved, and 72% of the skin retained moisture.
彈力蛋白是一種淡黃色的萃取液，彈力蛋白是人體會自動生成的蛋白質之一，彈力蛋白的功能是維持肌膚彈力。彈力蛋白主要的功效是能有效改善皮膚的結締組織，促進細胞再生，使肌膚緊實有彈性。所以彈力蛋白主要是針對抗皺，還有附加保濕效果。以1~10 wt%用量進行為期八周的人體實驗，針對20位20到48歲，中度至重度肌膚細胞老化、皮膚乾燥、肌膚缺乏水分的民眾，臨床實驗後發現，有65%的受測者表示其膚色不均獲得改善，79%提升肌膚亮澤度，8 1%粗糙、乾燥的肌膚獲得改善，還有83%表示補充肌膚水分。Elastin is a light yellow extract. Elastin is one of the proteins produced automatically by the human body. The function of elastin is to maintain skin elasticity. The main function of elastin is to effectively improve the connective tissue of the skin, promote cell regeneration, and make the skin firm and elastic. Therefore, elastin is mainly aimed at anti-wrinkle, and has an additional moisturizing effect. An eight-week human experiment was carried out at a dosage of 1-10 wt%, targeting 20 people aged 20 to 48 with moderate to severe skin cell aging, dry skin, and lack of moisture in the skin. After the clinical experiment, it was found that 65% of the people affected The testers said that their uneven skin tone has been improved, 79% have improved skin radiance, 81% have improved rough and dry skin, and 83% have replenished skin moisture.
维生素C糖苷是一種米黃色的萃取液，含有最穩定的維他命C衍生物，能夠完整的被肌膚所利用，發揮深層美白的功效，改善肌膚暗沉，使膚色均勻而亮麗，並且不具刺激性，能幫助皮膚改善，平均給予皮膚色澤，不會產生明顯的色差問題，可加強維生素C的作用並且具有舒緩肌膚的效果。以2 wt%用量進行為期八周的人體實驗，針對20位15到40歲，中度至重度肌膚缺乏水分、肌膚膚色偏黑、肌膚暗沉的民眾，臨床實驗後發現，有73%的受測者表示撫平肌膚細紋，82%提升肌膚保濕度，69%均勻肌膚膚色，還有87%表示提升肌膚明亮度。Vitamin C glucoside is a beige extract containing the most stable vitamin C derivatives, which can be completely utilized by the skin to exert a deep whitening effect, improve dull skin, and make the skin tone even and bright without irritation. It can help the skin to improve, give the skin an average color, and will not cause obvious color difference problems. It can strengthen the effect of vitamin C and has the effect of soothing the skin. An eight-week human experiment was carried out at a dosage of 2 wt%. Aiming at 20 people aged 15 to 40 with moderate to severe skin dehydration, dark skin, and dull skin, it was found after the clinical experiment that 73% of the people affected The testers said that it smoothed the skin fine lines, 82% improved skin moisture, 69% evened skin tone, and 87% said it improved skin brightness.
白芷是一種褐色的萃取液，白芷味香色白，為古老的美容中藥之一，白芷萃取液能夠柔嫩肌膚、潤滑光澤，滋潤的容顏呈現出水一樣的靈氣，並可改善微循環，促進皮膚的新陳代謝，延緩皮膚衰老。以5~10 wt%用量進行為期八周的人體實驗，針對20位15到40歲，中度至重度黑肌膚、肌膚暗沉、有黑眼圈的民眾，臨床實驗後發現，有86%的受測者表示其偏黑的肌膚獲得改善，77%提升肌膚亮澤度，86%改善暗沉的肌膚，68%改善黑眼圈的狀況，還有75%表示粗糙乾燥的肌膚獲得改善。Angelica dahurica is a kind of brown extract, which is fragrant and white in color. It is one of the ancient beauty traditional Chinese medicines. The extract of Angelica dahurica can soften the skin, lubricate the luster, and the moisturized face will show a water-like aura, and it can improve microcirculation and promote skin metabolism. Delay skin aging. An eight-week human experiment was carried out at a dosage of 5~10 wt%. Aiming at 20 people aged 15 to 40 with moderate to severe dark skin, dull skin, and dark circles, it was found after the clinical experiment that 86% of the people affected The testers said that their dark skin has been improved, 77% have improved skin brightness, 86% have improved dull skin, 68% have improved dark circles, and 75% have improved rough and dry skin.
經過實驗測試，10 wt%的海椰子、8 wt%的黑綿羊胎盤、5 wt%的聖潔莓、3 wt%的傳明酸、5 wt%的α熊果素、5 wt%的桑白皮、3 wt%的木瓜酵素、1 wt%的奈米珍珠液、3 wt%的彈力蛋白、2 wt%的维生素C糖苷、5 wt%的白芷以及50%的水所調配出的複合液具有最佳的皮膚美白效果，不會刺激皮膚且效果持續，經過八周的人體實驗，針對20位18到45歲，中度至重度皮膚偏黑、肌膚暗沉的民眾，臨床實驗後發現，有86%的受測者表示其偏黑的肌膚獲得改善，84%提升肌膚亮澤度，85%改善暗沉的肌膚，還有92%表示提昇肌膚的明亮度，從而達成本發明的目的。After experimental testing, 10 wt% sea coconut, 8 wt% black sheep placenta, 5 wt% chaste berry, 3 wt% tranexamic acid, 5 wt% α-arbutin, 5 wt% Morus alba, 3 wt% The complex solution prepared by wt% papaya enzyme, 1 wt% nano pearl liquid, 3 wt% elastin, 2 wt% vitamin C glycoside, 5 wt% Angelica dahurica and 50% water has the best The skin whitening effect will not irritate the skin and the effect lasts. After eight weeks of human experiments, 20 people aged 18 to 45 with moderate to severe dark skin and dull skin. After clinical experiments, it was found that 86% The subjects indicated that their dark skin was improved, 84% improved skin brightness, 85% improved dull skin, and 92% expressed that skin brightness was improved, thereby achieving the purpose of the present invention.
基於本發明之設計精神，該外用皮膚美白複合液之成分可有其他變化，例如傳明酸、α熊果素、桑白皮、木瓜酵素、奈米珍珠液、彈力蛋白、维生素C糖苷與白芷可依需要加減量或不添加，仍然具有極佳的美白功效。舉凡此等可輕易思及的變化，均應為本發明申請專利範圍所涵蓋。Based on the design spirit of the present invention, the composition of the skin whitening compound solution for external use may have other changes, such as tranexamic acid, α-arbutin, Morus alba, papaya enzyme, nano pearl liquid, elastin, vitamin C glycoside and Angelica dahurica It needs to be added or subtracted or not added, and it still has excellent whitening effect. All these easily conceivable changes should be covered by the patent scope of the present invention.
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