TW202246484A - 細胞培養用微載體及細胞之培養方法 - Google Patents

細胞培養用微載體及細胞之培養方法 Download PDF

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TW202246484A
TW202246484A TW111104290A TW111104290A TW202246484A TW 202246484 A TW202246484 A TW 202246484A TW 111104290 A TW111104290 A TW 111104290A TW 111104290 A TW111104290 A TW 111104290A TW 202246484 A TW202246484 A TW 202246484A
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Taiwan
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microcarrier
mentioned
cell culture
meth
microcarriers
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TW111104290A
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Chinese (zh)
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髙倉健太
羽根田聡
中村雄太
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日商積水化學工業股份有限公司
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Publication of TW202246484A publication Critical patent/TW202246484A/zh

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    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/0068General culture methods using substrates
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K5/00Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/10Tetrapeptides
    • C07K5/1019Tetrapeptides with the first amino acid being basic
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12MAPPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M23/00Constructional details, e.g. recesses, hinges
    • C12M23/20Material Coatings
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12MAPPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M25/00Means for supporting, enclosing or fixing the microorganisms, e.g. immunocoatings
    • C12M25/16Particles; Beads; Granular material; Encapsulation
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/0068General culture methods using substrates
    • C12N5/0075General culture methods using substrates using microcarriers
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K7/00Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/64Cyclic peptides containing only normal peptide links
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2533/00Supports or coatings for cell culture, characterised by material
    • C12N2533/30Synthetic polymers
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2533/00Supports or coatings for cell culture, characterised by material
    • C12N2533/30Synthetic polymers
    • C12N2533/40Polyhydroxyacids, e.g. polymers of glycolic or lactic acid (PGA, PLA, PLGA); Bioresorbable polymers
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2533/00Supports or coatings for cell culture, characterised by material
    • C12N2533/50Proteins

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Microbiology (AREA)
  • General Engineering & Computer Science (AREA)
  • Sustainable Development (AREA)
  • Immunology (AREA)
  • Cell Biology (AREA)
  • Clinical Laboratory Science (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
TW111104290A 2021-02-03 2022-02-07 細胞培養用微載體及細胞之培養方法 TW202246484A (zh)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
JP2021-015724 2021-02-03
JP2021015724 2021-02-03
JP2021-141461 2021-08-31
JP2021141461 2021-08-31

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TW202246484A true TW202246484A (zh) 2022-12-01

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TW111104290A TW202246484A (zh) 2021-02-03 2022-02-07 細胞培養用微載體及細胞之培養方法
TW111104289A TW202242089A (zh) 2021-02-03 2022-02-07 細胞培養用微載體及細胞培養方法

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US (2) US20240052302A1 (https=)
EP (2) EP4289931A4 (https=)
JP (3) JP7813732B2 (https=)
TW (2) TW202246484A (https=)
WO (2) WO2022168871A1 (https=)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20240052301A1 (en) * 2021-02-03 2024-02-15 Sekisui Chemical Co., Ltd. Microcarrier for cell culture and cell culture method
CA3239283A1 (en) * 2021-12-27 2023-07-06 Sekisui Chemical Co., Ltd. Coating solution for forming cell scaffold and production method thereof

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5426396B2 (https=) * 1974-06-04 1979-09-04
EP0101724A1 (en) * 1982-02-23 1984-03-07 Ventrex Laboratories Inc. Multipurpose supports for immunological and biological use
JP2827298B2 (ja) * 1989-07-10 1998-11-25 三菱化学株式会社 細胞培養担体
JPH0638730A (ja) * 1991-02-01 1994-02-15 Sakai Enetsukusu Kk 動物細胞培養用担体
US6214618B1 (en) * 1998-04-07 2001-04-10 Solohill Engineering, Inc. Microcarrier beads having a styrene copolymer core and a covalently linked tri-methylamine exterior
US9296988B2 (en) * 2009-06-19 2016-03-29 The Regents Of The University Of California Three-dimensional cell adhesion matrix
EP2459701A1 (en) 2009-07-28 2012-06-06 Corning Inc. Synthetic microcarriers for culturing cells
EP2459704A1 (en) 2009-07-28 2012-06-06 Corning Inc. High surface area substrate for cell culture
JP2011030453A (ja) * 2009-07-30 2011-02-17 Sanyo Chem Ind Ltd 細胞の生産方法
US20110207216A1 (en) * 2010-02-25 2011-08-25 Arthur Winston Martin Synthetic Peptide (Meth) Acrylate Microcarriers
US20120052579A1 (en) * 2010-08-27 2012-03-01 Simon Kelly Shannon Peptide-modified microcarriers for cell culture
JP2016171794A (ja) * 2015-03-17 2016-09-29 国立研究開発法人産業技術総合研究所 担体及び細胞培養方法
CN113366100A (zh) * 2019-03-29 2021-09-07 积水化学工业株式会社 细胞培养用支架材料、细胞培养用容器、细胞培养用载体、细胞培养用纤维和细胞的培养方法
CN115926568B (zh) * 2019-05-15 2025-05-09 积水化学工业株式会社 由细胞培养用支架材料形成的树脂膜、细胞培养用载体和细胞培养用容器

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WO2022168871A1 (ja) 2022-08-11
EP4289931A4 (en) 2025-02-12
EP4289936A4 (en) 2025-02-12
JP2026063527A (ja) 2026-04-10
US20240309317A1 (en) 2024-09-19
EP4289936A1 (en) 2023-12-13
TW202242089A (zh) 2022-11-01
US20240052302A1 (en) 2024-02-15
JP7813732B2 (ja) 2026-02-13
EP4289931A1 (en) 2023-12-13
JP7815151B2 (ja) 2026-02-17
WO2022168872A1 (ja) 2022-08-11
JPWO2022168871A1 (https=) 2022-08-11
JPWO2022168872A1 (https=) 2022-08-11

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