JP7813732B2 - 細胞培養用マイクロキャリア及び細胞の培養方法 - Google Patents

細胞培養用マイクロキャリア及び細胞の培養方法

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Publication number
JP7813732B2
JP7813732B2 JP2022579579A JP2022579579A JP7813732B2 JP 7813732 B2 JP7813732 B2 JP 7813732B2 JP 2022579579 A JP2022579579 A JP 2022579579A JP 2022579579 A JP2022579579 A JP 2022579579A JP 7813732 B2 JP7813732 B2 JP 7813732B2
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Japan
Prior art keywords
microcarrier
meth
microcarriers
cell culture
peptide
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Active
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JP2022579579A
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English (en)
Japanese (ja)
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JPWO2022168871A1 (https=
Inventor
健太 ▲高▼倉
聡 羽根田
雄太 中村
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sekisui Chemical Co Ltd
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Sekisui Chemical Co Ltd
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Publication of JPWO2022168871A1 publication Critical patent/JPWO2022168871A1/ja
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Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/0068—General culture methods using substrates
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/10—Tetrapeptides
    • C07K5/1019—Tetrapeptides with the first amino acid being basic
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M23/00—Constructional details, e.g. recesses, hinges
    • C12M23/20—Material Coatings
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M25/00—Means for supporting, enclosing or fixing the microorganisms, e.g. immunocoatings
    • C12M25/16—Particles; Beads; Granular material; Encapsulation
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/0068—General culture methods using substrates
    • C12N5/0075—General culture methods using substrates using microcarriers
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/64—Cyclic peptides containing only normal peptide links
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2533/00—Supports or coatings for cell culture, characterised by material
    • C12N2533/30—Synthetic polymers
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2533/00—Supports or coatings for cell culture, characterised by material
    • C12N2533/30—Synthetic polymers
    • C12N2533/40—Polyhydroxyacids, e.g. polymers of glycolic or lactic acid (PGA, PLA, PLGA); Bioresorbable polymers
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2533/00—Supports or coatings for cell culture, characterised by material
    • C12N2533/50—Proteins

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Microbiology (AREA)
  • General Engineering & Computer Science (AREA)
  • Sustainable Development (AREA)
  • Immunology (AREA)
  • Cell Biology (AREA)
  • Clinical Laboratory Science (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
JP2022579579A 2021-02-03 2022-02-02 細胞培養用マイクロキャリア及び細胞の培養方法 Active JP7813732B2 (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
JP2021015724 2021-02-03
JP2021015724 2021-02-03
JP2021141461 2021-08-31
JP2021141461 2021-08-31
PCT/JP2022/004062 WO2022168871A1 (ja) 2021-02-03 2022-02-02 細胞培養用マイクロキャリア及び細胞の培養方法

Publications (2)

Publication Number Publication Date
JPWO2022168871A1 JPWO2022168871A1 (https=) 2022-08-11
JP7813732B2 true JP7813732B2 (ja) 2026-02-13

Family

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Family Applications (3)

Application Number Title Priority Date Filing Date
JP2022579579A Active JP7813732B2 (ja) 2021-02-03 2022-02-02 細胞培養用マイクロキャリア及び細胞の培養方法
JP2022579580A Active JP7815151B2 (ja) 2021-02-03 2022-02-02 細胞培養用マイクロキャリア及び細胞の培養方法
JP2026016797A Pending JP2026063527A (ja) 2021-02-03 2026-02-04 細胞培養用マイクロキャリア及び細胞の培養方法

Family Applications After (2)

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JP2022579580A Active JP7815151B2 (ja) 2021-02-03 2022-02-02 細胞培養用マイクロキャリア及び細胞の培養方法
JP2026016797A Pending JP2026063527A (ja) 2021-02-03 2026-02-04 細胞培養用マイクロキャリア及び細胞の培養方法

Country Status (5)

Country Link
US (2) US20240052302A1 (https=)
EP (2) EP4289931A4 (https=)
JP (3) JP7813732B2 (https=)
TW (2) TW202246484A (https=)
WO (2) WO2022168871A1 (https=)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20240052301A1 (en) * 2021-02-03 2024-02-15 Sekisui Chemical Co., Ltd. Microcarrier for cell culture and cell culture method
CA3239283A1 (en) * 2021-12-27 2023-07-06 Sekisui Chemical Co., Ltd. Coating solution for forming cell scaffold and production method thereof

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2011030453A (ja) 2009-07-30 2011-02-17 Sanyo Chem Ind Ltd 細胞の生産方法
JP2013500717A (ja) 2009-07-28 2013-01-10 コーニング インコーポレイテッド 細胞を培養するための合成マイクロキャリア
JP2016171794A (ja) 2015-03-17 2016-09-29 国立研究開発法人産業技術総合研究所 担体及び細胞培養方法
WO2020230884A1 (ja) 2019-05-15 2020-11-19 積水化学工業株式会社 細胞培養用足場材料及び細胞培養用容器

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5426396B2 (https=) * 1974-06-04 1979-09-04
EP0101724A1 (en) * 1982-02-23 1984-03-07 Ventrex Laboratories Inc. Multipurpose supports for immunological and biological use
JP2827298B2 (ja) * 1989-07-10 1998-11-25 三菱化学株式会社 細胞培養担体
JPH0638730A (ja) * 1991-02-01 1994-02-15 Sakai Enetsukusu Kk 動物細胞培養用担体
US6214618B1 (en) * 1998-04-07 2001-04-10 Solohill Engineering, Inc. Microcarrier beads having a styrene copolymer core and a covalently linked tri-methylamine exterior
US9296988B2 (en) * 2009-06-19 2016-03-29 The Regents Of The University Of California Three-dimensional cell adhesion matrix
EP2459704A1 (en) 2009-07-28 2012-06-06 Corning Inc. High surface area substrate for cell culture
US20110207216A1 (en) * 2010-02-25 2011-08-25 Arthur Winston Martin Synthetic Peptide (Meth) Acrylate Microcarriers
US20120052579A1 (en) * 2010-08-27 2012-03-01 Simon Kelly Shannon Peptide-modified microcarriers for cell culture
CN113366100A (zh) * 2019-03-29 2021-09-07 积水化学工业株式会社 细胞培养用支架材料、细胞培养用容器、细胞培养用载体、细胞培养用纤维和细胞的培养方法

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2013500717A (ja) 2009-07-28 2013-01-10 コーニング インコーポレイテッド 細胞を培養するための合成マイクロキャリア
JP2011030453A (ja) 2009-07-30 2011-02-17 Sanyo Chem Ind Ltd 細胞の生産方法
JP2016171794A (ja) 2015-03-17 2016-09-29 国立研究開発法人産業技術総合研究所 担体及び細胞培養方法
WO2020230884A1 (ja) 2019-05-15 2020-11-19 積水化学工業株式会社 細胞培養用足場材料及び細胞培養用容器

Also Published As

Publication number Publication date
WO2022168871A1 (ja) 2022-08-11
TW202246484A (zh) 2022-12-01
EP4289931A4 (en) 2025-02-12
EP4289936A4 (en) 2025-02-12
JP2026063527A (ja) 2026-04-10
US20240309317A1 (en) 2024-09-19
EP4289936A1 (en) 2023-12-13
TW202242089A (zh) 2022-11-01
US20240052302A1 (en) 2024-02-15
EP4289931A1 (en) 2023-12-13
JP7815151B2 (ja) 2026-02-17
WO2022168872A1 (ja) 2022-08-11
JPWO2022168871A1 (https=) 2022-08-11
JPWO2022168872A1 (https=) 2022-08-11

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