TW202210087A - Ionized water essential oil dental cleaning solution - Google Patents

Abstract

The present invention relates an oral care composition, comprising an oily ingredient; a solvent, a solubilizing ingredient and a flavoring ingredients; whereas the Lemon Myrtle oil with the proportion of between 0.1 and 0.8 percent w/w to form oily ingredient; the Ionized Water with the proportion of between 83.0 and 95.0 percent w/w to form solvent; the Coconut extract with the proportion of between 4.0 and 10.0 percent w/w to form solubilizing ingredient; further mixing sweetener and fragrance; which prepared process comprises the following steps (1)mixing the oily ingredient, solubilizing ingredient and fragrance; (2)mixing the solvent and sweetener, and (3) further mixed the mixture of the pre-process (1) and (2). The pH range of the composition is more than 11.

Description

Tooth cleaning oil electrolyte

The invention relates to an oral care composition, which comprises: an oily component; a solvent; a component with a solubilizing effect, and a flavoring component; wherein the oily component is 0.1-0.8W/W% lemon myrtle essential oil (lemon myrtle oil); the solvent is 83.0~95.0W/W% electrolyte (ionized water); the solubilizing component is 4.0~10.0W/W% coconut extract; the flavoring component is sweetener, aromatic agent The present invention Corresponding pharmaceutical formulations, uses, methods, processes, commercial products and related examples are also disclosed.

The patent report of the existing oral health care technology, involving the Republic of China Patent No. I671079 discloses an oral composition, which contains phytic acid or its alkali metal salt, increases the amount of fluoride adsorption of teeth, and improves the whitening effect or gloss imparting effect of teeth . National Patent No. I551300 discloses an oral health care composition comprising zinc lactate, zinc citrate, zinc oxide and zinc chloride, and an oral health care composition for reducing halitosis. National Patent No. TWI382852 discloses a calcium phosphate compound for oral health care and its preparation method and composition, which comprises calcium phosphate compound with mucoadhesion, which can increase the residence time in the oral cavity, buffer the acidity in the mouth, and achieve prevention and improvement of dental caries, etc. Oral health effects.

In view of the imperfections of the known technology, the inventor finally came up with the case "Ionized Water Essential Oil Dental Cleaning Solution" after careful testing and research, and a spirit of perseverance, which can overcome the problems of the prior art. Insufficient, the following is a brief description of the case.

The Ministry of Health and Welfare compared the results of the survey on the dental caries rate of young children in 2011 and 1997. The dental caries rate of children aged 2-3 and 5-6 years showed a decrease, but the increase in the dental caries rate from the age of 3 to 6 years remained at the same level. About 40%, there is still a considerable gap with the target set by the World Health Organization (WHO). Obviously, the oral health of Chinese people is not good.

There are many lesions in the oral cavity, such as caries, plaque, periodontal disease, calculus, gum disease, bad breath, ulcers, dry mouth, and mouth sores. There is enamel on the surface of the tooth crown. When food residues such as sugars remain in the oral cavity, the Streptoccocus mutans in the sugar or food secrete acidic substances, which are accompanied by Lactobacillus (Lactobacillus) reproduction to produce a large amount of enamel. Lactic acid, which reduces the acidity and alkalinity in the mouth. This acidity causes decalcification and corrosion of tooth enamel, and demineralizes the tooth. After a long period of time, destructive changes will occur, and a cavity or cavity is formed in the tooth enamel, which is commonly known as tooth decay. Aging, or degeneration of physiological functions, leads to weakened salivary gland function and reduced saliva secretion, resulting in dry mouth symptoms. The pH of saliva is about 6.2~7.6, which acts as a buffer pH in the oral cavity, and the decrease in the amount of saliva secretion reduces the buffering phenomenon and causes the oral environment to be more acidic, which is enough to greatly increase the incidence of dental caries.

In addition, microorganisms in the oral cavity combine with the diet to produce a substance that adheres to the surface of the teeth, forming what is commonly known as plaque or plaque. Plaque builds up in the tissues around the teeth, Causes soreness and inflammation of the gums and destroys the occlusion of the teeth. Pigment, or e-liquid, tea stains, soy sauce, caffeine and deposits in the mouth are deposited on the surface of the teeth, and even in the gap between the teeth, which is enough to cause yellowing and blackening of the teeth and plaque, especially in the gap between the teeth. In the oral cavity, due to the proliferation of microorganisms, sinusitis, lesions of the digestive system, and lesions in the body, the bad breath in the breath or the bad smell in the mouth is caused. Although individuals are unaware of the odor, it can cause embarrassment in social situations and problems affecting quality of life. Teeth and oral tissues are exposed to a complex environment for many years, and attention must be paid to oral hygiene.

According to one aspect of the present invention, the present invention relates to an oral care composition comprising: an oily ingredient; a solvent; and an ingredient having a solubilizing effect, adding a flavoring ingredient. The oily component is 0.1~0.8W/W% lemon myrtle essential oil; the solvent is 83.0~95.0W/W% electrolyte; the solubilizing component is 4.0~10.0W/W% coconut extract; the flavoring component is sweetness agent, fragrance. When preparing, measure and mix lemon myrtle essential oil, coconut extract and fragrance according to weight ratio, stir the electrolyte and sweetener, and then mix evenly oily component and solvent. The acidity and alkalinity (pH value) of the composition are above 11, and the appearance is a uniform fragrance solution, and no bacteriostatic agent needs to be added.

According to another aspect of the present invention, the present invention relates to a method for improving oral hygiene, comprising administering an effective amount of an oral care composition to the oral cavity of a person in need thereof; the method can achieve (1.) reduce or inhibit (2.) Reduce or inhibit demineralization and promote tooth remineralization; (3.) Reduce tooth hypersensitivity; (3.) Reduce tooth hypersensitivity; (4.) Reduce or inhibit gingivitis (5.) Inhibit the formation of microbial biofilms in the oral cavity; (6.) Treat and/or reduce the accumulation of tartar and plaque; (7.) Clean the teeth and/or the oral cavity; (8.) Treat and/or reduce bad breath.

According to another aspect of the present invention, the present invention relates to a method of applying an oral care composition, comprising storing the composition in the form of a uniformly fragrant solution in a spray device, spraying on a toothbrush, and also spraying on teeth and dentures , brush with a toothbrush. It is stored in a spray device and sprayed directly in the mouth for gargling care. In addition, it can be stored in a spray foam device, and the composition can be stored in a solution bottle, dripped on a toothbrush to clean teeth, dentures, and brushed with a toothbrush.

Usually toothpastes contain fluoride, abrasives, antibacterial agents, essential oils, or add Chinese herbal extracts, or emphasize alkalinity. Mouthwashes contain alcohol, essential oils, and surfactants. Mouthwashes contain alcohol as a solvent for the active ingredient, surfactants to dissolve essential oils or other ingredients such as antimicrobials. Among them, toothpaste is an abrasive, which is used to clean the surface of teeth. The role of fluoride is to strengthen the acid resistance of the tooth structure, and by slowing down the demineralization of the teeth, it can prevent the progression of dental caries. However, fluoride is easily washed away by saliva and cannot remain in the oral cavity for a long time, and its efficacy is limited. Chinese herbal extracts are mainly used for anti-inflammatory, anti-stomach ulcer and antibacterial effects. Research has found that some of the above-mentioned active ingredients are affected by surfactants in the formula, while some antibacterial and antimicrobial ingredients may cause bacteria to develop resistance for a long time.

When the pH value in the oral cavity is lower than 5.5 and is acidic, the calcium hydroxide phosphate in the enamel reacts with the acidic components in the oral cavity, resulting in the demineralization of the tooth enamel and the loss of calcium. Known technology for dental caries, products often use fluoride or alkaline formulations that are expected to inhibit the growth of bacteria in the mouth, or buffer the acidity generated by the metabolism of soft drinks and bacteria, and even It has the ability to promote the restoration of teeth, which is beneficial to prevent and improve dental caries, and avoid problems such as pain and even missing teeth.

At various levels of the present inventive concept, a method of administration and compositions for improving oral hygiene in mammals are directed. The composition comprises: an oily component; a solvent; and a component with a solubilizing effect, adding a flavoring component; wherein the oily component is 0.1-0.8W/W% lemon myrtle essential oil; the solvent is 83.0-95.0W/ W% electrolyte; the solubilizing component is 4.0~10.0W/W% coconut extract; the flavoring components are sweeteners and aromatics, and the appearance is a uniform aromatic solution whose pH value is above 11.

The solvent constituting the composition of the present invention adopts an electrolyte solvent to make a conventional electrolytic ionized water generator (Ionic Water Generator), with a terminal voltage of 7 volts and a current of 0.3 amperes, or 6.5 volts and a current of 0.35 amperes, Add sodium chloride or potassium carbonate to make it. Produces a high pH electrolyte with properties similar to those commonly known as alkaline electrolyzed water.

According to Ke Ziting's master's thesis at the National Pingtung University of Science and Technology in 2005, on "the effect of the strong alkaline pH value and high reducing potential of alkaline electrolyzed water on the food system and the evaluation of the antioxidant capacity", the salt-added alkali Due to the addition of electrolyte, alkaline electrolyzed water can have a higher pH value than non-salted alkaline electrolyzed water. Alkaline electrolyzed water interacts with organic matter, showing a similar buffering effect, and its high pH value decreases accordingly. Alkaline electrolyzed water exhibits the ability to help antioxidants, which means that the cation precipitation concentration is also higher.

It is known that the lemon peach ( Backhousia citriodora ) dried in the shade has a pH of about 5.5 to 6.5. According to Ian Edwin Cook et al., Pharmacognosy Communications, Vol. 3(2), pp. 58-63, 2013, on Antimicrobial activity of Backhousia citriodora (Lemon Myrtle) methanolic extracts, the antibacterial activity of Lemon Myrtle extract was determined in Ten of the 11 Gram-negative strains tested were inhibited in growth by about 91%. The 1 hour culture exhibited significant growth inhibition for Bacillus cereus , Bacillus subtilis , Aeromonas hydrophilia and Pseudomonas fluorescens .

According to Navneet Kishore et al. published in 2020 about Cococonut Palm (Coconut L.) A Natural Gift to Humans for Dental Ministration (https://doi.org/10.1002/9781119618973.ch17), coconut oil has significant antibacterial, antibacterial and antibacterial properties. Fungal and antiviral properties, eliminate harmful microorganisms in the mouth. The pH of coconut extract is about 5.2~6.3. In the process of making the composition, the oily solution and the aqueous solution are fully mixed, and it acts as an emulsifier, so the appearance is a uniform aromatic solution.

In 2013, Ena Gupta et al. published a study on Nutritional and therapeutic values of Stevia rebaudiana : A review in Journal of Medicinal Plants Research 3343-3353, suggesting that Stevia rebaudiana has antioxidant, antibacterial, antifungal and anticarcinogenic activities. Can be a major source of high-potency, low-calorie sweeteners. When the pH in the oral cavity is lower than 5.5 and is acidic, the mutants of Streptococcus are still unable to ferment xylitol, so the enamel can avoid demineralization or remineralization, and can stabilize the gums. The pH of xylitol is about 4.5~6.5.

The components of peppermint oil are menthol and menthone. The pH value is in a wide range from 3.0 to 7.0 depending on the source. It has a special fresh taste and an aromatic cooling sensation after use. It exhibits antibacterial activity against Staphylococcus epidermidis and Escherichia coli , and also has anti-allergic effects. It is often used in cosmeceuticals, personal hygiene products, food and pharmaceutical products.

The preparation steps of the composition of the present invention are as follows: 1. soak the vacuum stirring vessel, the stainless steel stirring vessel and the carrying vessel in flowing sterile water, rinse for 5 minutes, soak in the bacteria water, change the water every 1 hour, and repeat three times at last Change to electrolyte and dry to maintain sterility.

②Put the acid-base (pH above 12) electrolyte 83.0~95.0W/W% into the vacuum stirring vessel, add xylitol 1.0~6.0W/W%, stevia 0.1~1.0 W//W% stirring to become an aqueous homogeneous aromatic solution;

③Put peppermint oil 0.1~0.8W/W%, lemon myrtle essential oil 0.1~0.8W/W%, coconut extract 4.0~10.0W/W% in sequence into a stainless steel stirring vessel and stir thoroughly to form Oily homogeneous fragrance solution;

4. The sufficiently uniform step ③ oily solution is slowly poured into the homogeneous aqueous solution of step 2 in the vacuum stirring vessel, and after thorough mixing, the coconut extract is subjected to an emulsification reaction to become a uniform aromatic solution, and its acidity and alkalinity (pH value) are detected with test paper. ) is 11 or more, and it is divided into containers of each required capacity.

The composition comprises: an oily component; a solvent; and a component with a solubilizing effect, adding a flavoring component; wherein the oily component is 0.1-0.8W/W% lemon peach The preferred content of Jin Niang essential oil is 0.3-0.7W/W%, and the preferred content is 0.4-0.6W/W%. The solvent is 83.0-95.0W/W% electrolyte, and its preferred content is 85.0-89.0W/W%, and the preferred content is 87.0-90.0W/W%. The solubilizing component is 4.0-10.0W/W% coconut extract, and its preferred content is 5.0-9.0W/W%, and the preferred content is 6.0-8.5W/W%. One of the sweeteners is 0.1-1.0W/W% stevia, the preferred content of which is 0.3-0.7W/W%, and the preferred content is 0.4-0.6W/W%. Another sweetener is 1.0-6.0W/W% xylitol, the preferred content of which is 2.0-5.0W/W%, and the preferred content is 3.0-4.0W/W%. The fragrance is 0.1-0.8W/W% peppermint oil, and its preferred content is 0.3-0.7W/W%, and the preferred content is 0.4-0.6W/W%.

The invention relates to an administration method for improving oral hygiene of mammals, which is to spray the composition stored in a carrying container directly in the oral cavity of humans to perform gargling care. The composition stored in the spray device can be directly sprayed on mammalian teeth and human dentures, and can be brushed with a toothbrush. The composition is stored in a solution bottle, dripped on a toothbrush and then brushed, and can also be cut into small droplets by the brushing power of the toothbrush to achieve the effect of cleaning teeth and dentures.

The composition is sprayed on the toothbrush, teeth, dentures or the oral surface in contact with it, or the small droplets formed by dripping on the toothbrush can not only guide the components of the composition to the teeth, dentures or the oral surface in contact with it, but also increase the acidity in the oral cavity. Alkaline (pH value), and then achieve the following effects, such as (1.) reducing or inhibiting the formation of dental caries; (2.) reducing or inhibiting demineralization and promoting tooth remineralization; (3.) reducing tooth decay Allergies; (4.) Reduce or inhibit gingivitis; (5.) Inhibit the formation of microbial biofilms in the oral cavity; (6.) Treat and/or reduce the accumulation of tartar and plaque; (7.) Clean teeth and/or or oral cavity; (8.) treatment and/or reduction of halitosis.

As used in this specification, ranges are simply used to describe each and every value within that range. Any value within the range can be selected as the endpoint of the range. Furthermore, all references cited herein are incorporated by reference in their entirety. Definitions of the present disclosure To the extent that a reference is cited, the present disclosure controls.

The following examples further describe and illustrate illustrative specific examples within the scope of the invention. These examples are purely illustrative and should not be construed as limiting the invention, since many variations are possible without departing from the spirit and scope of the invention. In addition to those shown and described in this case, various modifications of the present invention should be obvious to those skilled in the art, and therefore also fall within the scope of the patent application of this case.

Exemplary Embodiment (Exemplary Embodiment) 1

The present invention relates to a composition for improving oral hygiene. The composition has the appearance of a uniform fragrant solution, the acidity and alkalinity (pH value) of the composition are above 11, and the content of the essential oil of lemon myrtle is 0.6W/W%; the content of the electrolyte solution is 91.0 W/W%; coconut extract content is 6.0W/W%; stevia content is 0.4W/W%, xylitol content is 1.5W/W%; peppermint oil content is 0.5W/W%.

Exemplary Embodiment 2

The invention relates to a composition for oral care. The appearance of the composition is a uniform fragrant solution, the acidity and alkalinity (pH value) of the composition are above 11, the content of the essential oil of lemon myrtle is 0.5W/W%, and the content of the electrolyte solution is 91.0 W/W%; coconut extract content is 5.5W/W%; stevia content is 0.5W/W%, xylitol content is 2.0W/W%; peppermint oil contains The amount is 0.5W/W%.

Exemplary Embodiment 3

The invention relates to a composition for cleaning teeth. The appearance of the composition is a uniform fragrant solution, the acidity and alkalinity (pH value) of the composition are above 11, the content of essential oil of lemon myrtle is 0.6W/W%, and the content of the electrolyte solution is 90.0 W/W%; coconut extract content is 6.0W/W%; stevia content is 0.4W/W%, xylitol content is 2.6W/W%; peppermint oil content is 0.4W/W%.

Claims (10)

An oral care composition, comprising: an oily component; a solvent; and a component with a solubilizing effect, adding a flavoring component; wherein the oily component is 0.1-0.8W/W% lemon myrtle essential oil; the solvent is 83.0 ~95.0W/W% electrolyte; solubilizing ingredients are 4.0~10.0W/W% coconut extract; flavoring ingredients are sweeteners and aromatics; during production, measure lemon myrtle essential oil and coconut extract by weight The mixture is mixed with the aromatic agent, the electrolyte and the sweetener are stirred, and then the oily component and the solvent are mixed evenly; According to the composition of claim 1, wherein the sweetener is 0.1~1.0W/W% stevia and 1.0~6.0W/W% xylitol; the aroma agent is 0.1~0.8W/W% peppermint oil . For the composition of items 1-2 of the scope of application, the preferred content of lemon myrtle essential oil is 0.3-0.7W/W%; the preferred content of electrolyte is 85.0-89.0W/W%; the preferred content of coconut extract is The content is 5.0~9.0W/W%; the preferred content of stevia is 0.3~0.7W/W%, the preferred content of xylitol is 2.0~5.0W/W%; the preferred content of peppermint oil is 0.3~0.7W/W/ W%. A method for improving oral hygiene, comprising administering the composition in an effective amount of items 1 to 2 of the scope of application to the oral cavity of a mammal in need; this method can achieve (1.) reduce or inhibit the formation of dental caries; ( 2.) Reduce or inhibit demineralization and promote tooth remineralization; (3.) Reduce tooth hypersensitivity; (4.) Reduce or inhibit gingivitis; (5.) Inhibit the formation of microbial biofilms in the oral cavity; (6.) Treat and/or reduce tartar, plaque buildup; (7.) Clean teeth and/or mouth; (8.) Treat and/or reduce halitosis. According to the method of claim 4 of the scope of the application, the mammals include humans, cats, and dogs. A kind of oral care composition, it comprises lemon myrtle essential oil preferably content is 0.4～0.6W/W%; Electrolyte solution preferably content is 87.0～90.0W/W%; Coconut extract preferably content is 6.0～8.5W/W% The preferred content of stevia is 0.4～0.6W/W%, and the preferred content of xylitol is 3.0～4.0W/W%; Peppermint The preferred content of oil is 0.4 to 0.6 W/W %; the acidity and alkalinity (pH value) of the composition are 11 or more. A composition for cleaning teeth, comprising: an oily component; a solvent; and a component with a solubilizing effect, adding a flavoring component; wherein the oily component is 0.1-0.8W/W% lemon myrtle essential oil; The solvent is 83.0~95.0W/W% electrolyte; the solubilizing component is 4.0~10.0W/W% coconut extract; the flavoring component is sweetener and aromatic; when making, measure lemon myrtle essential oil by weight , coconut extract and aromatics are mixed, the electrolyte and sweetener are stirred, and then the oily components and solvent are mixed evenly; For the composition of claim 7, the sweeteners are 0.1~1.0W/W% stevia, 1.0~6.0W/W% xylitol; the aroma agent is 0.1~0.8W/W% peppermint oil ; The acidity and alkalinity (pH value) of the composition is 11 or more. For the composition of items 7-8 of the scope of application, the preferred content of lemon myrtle essential oil is 0.3-0.7W/W%; the preferred content of electrolyte is 85.0-89.0W/W%; the preferred content of coconut extract is The content is 5.0~9.0W/W%; the preferred content of stevia is 0.3~0.7W/W%, the preferred content of xylitol is 2.0~5.0W/W%; the preferred content of peppermint oil is 0.3~0.7W/W/ W%. A composition for cleaning teeth, comprising lemon myrtle essential oil with a preferred content of 0.4-0.6W/W%; an electrolyte with a preferred content of 87.0-90.0W/W%; coconut extract with a preferred content of 6.0-8.5W/W% The preferred content of stevioside is 0.4～0.6W/W%, and the preferred content of xylitol is 3.0～4.0W/W%; The preferred content of peppermint oil is 0.4～0.6W/W%; ) is 11 or more.