TW202133847A - 治療疼痛的方法 - Google Patents

治療疼痛的方法 Download PDF

Info

Publication number
TW202133847A
TW202133847A TW109142937A TW109142937A TW202133847A TW 202133847 A TW202133847 A TW 202133847A TW 109142937 A TW109142937 A TW 109142937A TW 109142937 A TW109142937 A TW 109142937A TW 202133847 A TW202133847 A TW 202133847A
Authority
TW
Taiwan
Prior art keywords
pain
compound
human
administered
dose
Prior art date
Application number
TW109142937A
Other languages
English (en)
Chinese (zh)
Inventor
詹姆士 菲利浦 強生
格雷果瑞 N 碧曲
Original Assignee
加拿大商再諾製藥公司
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by 加拿大商再諾製藥公司 filed Critical 加拿大商再諾製藥公司
Publication of TW202133847A publication Critical patent/TW202133847A/zh

Links

Images

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A61K31/472—Non-condensed isoquinolines, e.g. papaverine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
    • A61K31/137—Arylalkylamines, e.g. amphetamine, epinephrine, salbutamol, ephedrine or methadone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
    • A61K31/216—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acids having aromatic rings, e.g. benactizyne, clofibrate
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A61K31/485—Morphinan derivatives, e.g. morphine, codeine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/06—Antimigraine agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2300/00—Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biomedical Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Pain & Pain Management (AREA)
  • Emergency Medicine (AREA)
  • Rheumatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Light Guides In General And Applications Therefor (AREA)
  • Dental Tools And Instruments Or Auxiliary Dental Instruments (AREA)
TW109142937A 2019-12-06 2020-12-04 治療疼痛的方法 TW202133847A (zh)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US201962945093P 2019-12-06 2019-12-06
US62/945,093 2019-12-06
US201962948010P 2019-12-13 2019-12-13
US62/948,010 2019-12-13

Publications (1)

Publication Number Publication Date
TW202133847A true TW202133847A (zh) 2021-09-16

Family

ID=73856375

Family Applications (1)

Application Number Title Priority Date Filing Date
TW109142937A TW202133847A (zh) 2019-12-06 2020-12-04 治療疼痛的方法

Country Status (14)

Country Link
EP (1) EP4069211A1 (enExample)
JP (1) JP2023504166A (enExample)
KR (1) KR20220113411A (enExample)
CN (1) CN114786658A (enExample)
AU (1) AU2020397173A1 (enExample)
BR (1) BR112022010733A2 (enExample)
CA (1) CA3159436A1 (enExample)
CL (1) CL2022001477A1 (enExample)
CR (1) CR20220318A (enExample)
IL (1) IL293504A (enExample)
MX (1) MX2022006877A (enExample)
PE (1) PE20221169A1 (enExample)
TW (1) TW202133847A (enExample)
WO (1) WO2021113757A1 (enExample)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TWI771251B (zh) * 2021-10-27 2022-07-11 大陸商上海摯盟醫藥科技有限公司 作為鉀通道調節劑的化合物及其製備和應用

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN110511220B (zh) 2018-05-22 2022-04-01 上海挚盟医药科技有限公司 作为钾通道调节剂的对二氨基苯衍生物、其制备方法及其在医药上的应用

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9915414D0 (en) * 1999-07-01 1999-09-01 Glaxo Group Ltd Medical use
US7553858B2 (en) * 2003-12-17 2009-06-30 Meda Pharma Gmbh & Co. Kg Combination of flupirtine and tramadol
NZ575652A (en) 2006-08-23 2011-08-26 Valeant Pharmaceuticals Int Derivatives of 4-(n-azacycloalkyl) anilides as potassium channel modulators
US8993593B2 (en) * 2006-08-23 2015-03-31 Valeant Pharmaceuticals International N-(4-(6-fluoro-3,4-dihydroisoquinolin-2(1H)-yl)-2,6-dimethylphenyl)-3,3-dimethylbutanamide as potassium channel modulators
WO2013067591A1 (en) * 2011-11-10 2013-05-16 Relevare Australia Pty Ltd Topical formulations for pain management
US9248122B2 (en) * 2012-11-28 2016-02-02 Grünenthal GmbH Heteroquinoline-3-carboxamides as KCNQ2/3 modulators
MA52569B1 (fr) * 2018-05-11 2023-11-30 Xenon Pharmaceuticals Inc Méthodes pour améliorer la biodisponibilité et l'exposition d'un activateur de canal potassique voltage-dépendant

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TWI771251B (zh) * 2021-10-27 2022-07-11 大陸商上海摯盟醫藥科技有限公司 作為鉀通道調節劑的化合物及其製備和應用

Also Published As

Publication number Publication date
PE20221169A1 (es) 2022-07-25
WO2021113757A1 (en) 2021-06-10
AU2020397173A1 (en) 2022-06-23
EP4069211A1 (en) 2022-10-12
CN114786658A (zh) 2022-07-22
KR20220113411A (ko) 2022-08-12
CA3159436A1 (en) 2021-06-10
BR112022010733A2 (pt) 2022-08-23
CR20220318A (es) 2022-10-07
MX2022006877A (es) 2022-07-11
CL2022001477A1 (es) 2023-04-28
JP2023504166A (ja) 2023-02-01
IL293504A (en) 2022-08-01

Similar Documents

Publication Publication Date Title
ES2303085T3 (es) Composiciones que afectan a la perdida de peso.
JP2002541097A (ja) 線維筋痛症及び関連症状の治療におけるフルピルチン
US20240342156A1 (en) Methods for treating pain
TW200418474A (en) Method of treating post-operative nausea and vomiting
AU2021204517B2 (en) Combination of opioids and n-acylethanolamines
WO2015134405A1 (en) Therapeutic uses of ibogaine and related compounds
JP2017506244A (ja) ノルイボガイン及び関連化合物を用いた治療方法
RS59313B1 (sr) Orvepitant za lečenje hroničnog kašlja
JP2023504166A (ja) 疼痛の治療のためのKv7カリウムチャネル開口薬の使用
NO309965B1 (no) Oralt farmasøytisk antihostepreparat
KR20040020054A (ko) 통증 치료시 중독 예방
BR112019027889A2 (pt) método de tratamento e formas de dosagem do mesmo
US20080132531A1 (en) Synergistic combinations of norketamine and opioid analgesics
US10736874B1 (en) Methods for treating pain associated with sickle cell disease
US20070244102A1 (en) Combination of Dermaciclane and Opoids as Analgesics
CN110279691A (zh) 一种外科术后护理镇痛药物及其用途
HK40093852A (en) Combinations of opioids and n-acylethanolamines
HK40080562A (en) Use of a kv7 potassium channel opener for treating pain
US20090281194A1 (en) Combinations for treating HIV-associated pain
WO2018197638A1 (en) Novel use of (5r)-5-[5-[{2-[3,5-bis(trifluoromethyl)phenyl]-2-methylpropanoyl}(methyl)amino]-4-(4-fluoro-2-methylphenyl)-2-pyridinyl]-2-methyl-d-prolinamide