TW202110855A - 用於b型肝炎治療之新穎化合物及其醫藥組合物 - Google Patents

用於b型肝炎治療之新穎化合物及其醫藥組合物 Download PDF

Info

Publication number
TW202110855A
TW202110855A TW109117845A TW109117845A TW202110855A TW 202110855 A TW202110855 A TW 202110855A TW 109117845 A TW109117845 A TW 109117845A TW 109117845 A TW109117845 A TW 109117845A TW 202110855 A TW202110855 A TW 202110855A
Authority
TW
Taiwan
Prior art keywords
independently selected
substituted
compound
unsubstituted
alkyl
Prior art date
Application number
TW109117845A
Other languages
English (en)
Chinese (zh)
Inventor
捷克斯 漢克
奧斯卡 曼默爾堤
阿戴林 馬里 艾里斯 帕里斯
賽巴斯丁 理查
帕斯卡爾 皮爾 亞歷山卓 薩維
Original Assignee
比利時商葛萊伯格有限公司
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by 比利時商葛萊伯格有限公司 filed Critical 比利時商葛萊伯格有限公司
Publication of TW202110855A publication Critical patent/TW202110855A/zh

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D495/00Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
    • C07D495/02Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D495/04Ortho-condensed systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
TW109117845A 2019-05-29 2020-05-28 用於b型肝炎治療之新穎化合物及其醫藥組合物 TW202110855A (zh)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB1907547.2A GB201907547D0 (en) 2019-05-29 2019-05-29 Novel compounds and pharmaceutical compositions thereof for the treatment of hepatitis B
GB1907547.2 2019-05-29

Publications (1)

Publication Number Publication Date
TW202110855A true TW202110855A (zh) 2021-03-16

Family

ID=67385554

Family Applications (1)

Application Number Title Priority Date Filing Date
TW109117845A TW202110855A (zh) 2019-05-29 2020-05-28 用於b型肝炎治療之新穎化合物及其醫藥組合物

Country Status (4)

Country Link
AR (1) AR119030A1 (fr)
GB (1) GB201907547D0 (fr)
TW (1) TW202110855A (fr)
WO (1) WO2020239656A1 (fr)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US11964986B1 (en) 2023-07-03 2024-04-23 Rejuveron Telomere Therapeutics Ag 9-oxo-9,10-dihydro-6H-pyrano[3,2-b:4,5-b′]dipyridine-8-carboxylic acid derivatives

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2018022282A1 (fr) * 2016-07-29 2018-02-01 Newave Pharmaceutical Inc. Nouveaux agents thérapeutiques pour le traitement de l'infection par hbv.
GB201720163D0 (en) * 2017-12-04 2018-01-17 Galapagos Nv Novel compounds and pharmaceutical compositions thereof for the treatment of hepatitis B

Also Published As

Publication number Publication date
GB201907547D0 (en) 2019-07-10
WO2020239656A1 (fr) 2020-12-03
AR119030A1 (es) 2021-11-17

Similar Documents

Publication Publication Date Title
EP3720857B1 (fr) 2-oxo-5h-chromeno[4,3-b]pyridines destinées à être utilisées dans le traitement de l'hépatite b
JP7518049B2 (ja) Parp7阻害剤としてのピリダジノン
CN109311880B (zh) 用于治疗和预防乙型肝炎病毒感染的新的四氢吡啶并嘧啶类化合物
EP3535261B1 (fr) Nouvelles tétrahydropyridopyrimidines pour le traitement et la prophylaxie d'une infection par le virus de l'hépatite b
EP3464278B1 (fr) Dérivés de xanthone pour le traitement et la prophylaxie d'une maladie à virus de l'hépatite b
EP3328855B1 (fr) Nouveaux dérivés d'acide carboxylique tétracyclique 4-oxo-pyridine-3 pour le traitement et la prophylaxie d'une infection par le virus de l'hépatite b
JP6524355B2 (ja) Tlr7アゴニストとしての7−(チアゾール−5−イル)ピロロピリミジン化合物
AU2018246563B2 (en) 4-Pyridone compound or salt thereof, and pharmaceutical composition and formulation including same
TWI835999B (zh) 作為tlr7致效劑的咪唑并[2,1-f][1,2,4]三-4-胺衍生物
JP2018514575A (ja) B型肝炎ウイルス感染症の治療用のHBsAg(HBV表面抗原)及びHBV DNA産生の阻害剤としてのテトラヒドロピリドピリミジン類及びテトラヒドロピリドピリジン類
WO2017071516A1 (fr) Inhibiteur de kinase et procédé pour sa préparation et utilisation pharmaceutique correspondante
US8445501B2 (en) Substituted 7-carboxamido-pyrrolo[3,2-d]pyrimidines
KR20230057386A (ko) Apol1 억제제 및 사용 방법
AU2023218994A1 (en) 2-methyl-4',5'-dihydrospiro[piperidine-4,7'-thieno[2,3-c]pyran] derivatives as inhibitors of apol1 and methods of using same
WO2020192581A1 (fr) Inhibiteur de wee1 ainsi que sa préparation et son utilisation
IL270927A (en) Cyclic compounds and compositions are fused 5,6 to treat parasitic diseases
CN113045569B (zh) 用作ret激酶抑制剂的化合物及其应用
TW202110855A (zh) 用於b型肝炎治療之新穎化合物及其醫藥組合物
EP4446323A1 (fr) Composé de pyridine[4,3-d]pyrimidine utilisé en tant qu'agoniste du tlr7/8
CN118176195A (zh) 吡唑[3,4-d]嘧啶-3-酮类化合物及其医药用途
OA21175A (en) Inhibitors of APOL1 and methods of using same.