TW201822797A - 一種預防和治療腎纖維化的方法 - Google Patents
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- TW201822797A TW201822797A TW106120455A TW106120455A TW201822797A TW 201822797 A TW201822797 A TW 201822797A TW 106120455 A TW106120455 A TW 106120455A TW 106120455 A TW106120455 A TW 106120455A TW 201822797 A TW201822797 A TW 201822797A
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- A61P13/00—Drugs for disorders of the urinary system
- A61P13/12—Drugs for disorders of the urinary system of the kidneys
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- C—CHEMISTRY; METALLURGY
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- C12Y—ENZYMES
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| TW106120521A TWI642441B (zh) | 2016-12-15 | 2017-06-20 | 一種預防和治療藥物性腎損傷的方法 |
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| TW201822790A (zh) | 2016-12-15 | 2018-07-01 | 大陸商深圳瑞健生命科學研究院有限公司 | 一種預防和治療皮膚纖維化的方法 |
| DK3643321T3 (da) | 2017-06-19 | 2025-08-18 | Talengen Int Ltd | Plasminogen til anvendelse i behandling af parkinsons og alzheimers sygdom |
| TWI868051B (zh) * | 2017-06-23 | 2025-01-01 | 美商波麥堤克生物治療股份有限公司 | 與pai-1過表現相關之病狀的纖維蛋白溶酶原治療 |
| CN113456579B (zh) * | 2021-07-12 | 2023-04-25 | 南开大学 | 具有双靶点的hdac抑制剂的纳米胶束-水凝胶制剂在治疗急性肾损伤药物中的应用 |
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| US3773919A (en) | 1969-10-23 | 1973-11-20 | Du Pont | Polylactide-drug mixtures |
| IE52535B1 (en) | 1981-02-16 | 1987-12-09 | Ici Plc | Continuous release pharmaceutical compositions |
| CN87104683A (zh) * | 1986-05-15 | 1988-12-21 | 埃默里大学 | 改善血纤维蛋白溶解作用的组合物 |
| SI1516628T1 (sl) | 1995-07-27 | 2013-10-30 | Genentech, Inc. | Stabilna izotonična liofilizirana proteinska formulacija |
| US7202066B2 (en) | 2002-01-29 | 2007-04-10 | Carrington Laboratories, Inc. | Combination of a growth factor and a protease enzyme |
| CN1768138A (zh) * | 2002-02-06 | 2006-05-03 | N-酶生物技术有限公司 | 在微生物中生产重组蛋白质的方法 |
| CN1668312A (zh) * | 2002-05-13 | 2005-09-14 | 洛杉矶儿童医院 | 疤痕疙瘩和其它的皮肤或内部的创伤或损伤中异常疤痕形成的处理和抑制 |
| ATE331708T1 (de) * | 2002-12-10 | 2006-07-15 | Wyeth Corp | Substituierte 3-alkyl- und 3-arylalkyl-1h-indol-1-yl-essigsäure-derivate als plasminogen aktivator inhibitor-1 (pai-1) inhibitoren |
| US20050250694A1 (en) * | 2003-10-10 | 2005-11-10 | Ma Jian-Xing | Compounds useful in inhibiting vascular leakage, inflammation and fibrosis and methods of making and using same |
| AU2005277137A1 (en) * | 2004-08-23 | 2006-03-02 | Wyeth | Pyrrolo-naphthyl acids as PAI-1 inhibitors |
| US8741260B2 (en) | 2005-10-07 | 2014-06-03 | Armagen Technologies, Inc. | Fusion proteins for delivery of GDNF to the CNS |
| DK2056864T3 (en) * | 2006-08-28 | 2014-03-10 | Omnio Healer Ab | CANDIDATES AGAINST INFECTION |
| US20120129721A1 (en) * | 2009-05-26 | 2012-05-24 | Universidad De Salamanca | Urinary gm2 activator protein as a marker of acute renal failure or the risk of developing acute renal failure |
| WO2011004011A1 (en) * | 2009-07-10 | 2011-01-13 | Thrombogenics Nv | Variants of plasminogen and plasmin |
| CN102121023B (zh) * | 2010-12-22 | 2012-07-04 | 中山大学 | 突变型人纤溶酶原kringle5及其制备方法及应用 |
| JP6085568B2 (ja) * | 2011-01-05 | 2017-02-22 | スロンボジェニックス・ナムローゼ・フェンノートシャップThromboGenics NV | プラスミノーゲンおよびプラスミンの変異体 |
| CN102154253A (zh) | 2011-01-06 | 2011-08-17 | 郑州大学 | 具有抑制血小板凝集功能的微小纤溶酶原突变体及其制备方法和用途 |
| CN103987397A (zh) * | 2011-09-29 | 2014-08-13 | 梅约医学教育与研究基金会 | 芳族阳离子肽和使用它们的方法 |
| KR20160035077A (ko) | 2013-08-13 | 2016-03-30 | 사노피 | 플라스미노겐 활성인자 저해제-1(pai-1)에 대한 항체 및 그의 용도 |
| JP6512213B2 (ja) * | 2014-02-21 | 2019-05-15 | アステラス製薬株式会社 | 新規抗ヒトpai−1抗体 |
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| JP7242057B2 (ja) | 2023-03-20 |
| WO2018107700A1 (zh) | 2018-06-21 |
| TW202123962A (zh) | 2021-07-01 |
| CA3047170A1 (en) | 2018-06-21 |
| TW201822793A (zh) | 2018-07-01 |
| TW201822794A (zh) | 2018-07-01 |
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