TW201713354A - Aerosol type composition for preventing hair loss or promoting hair growth - Google Patents

Abstract

Disclosed is an aerosol type composition including ginseng extract. The composition realizes an aerosol formulation providing a maximized effect of active ingredients contained in ginseng by using a liquefied gas suitable therefor. Therefore, unlike the conventional hair loss-preventing agent having a liquid formulation, the aerosol formulation does not run down upon the application to the scalp to show an excellent feeling of use, allows the active ingredients of ginseng to be retained on the scalp for a long time to increase the infiltration time thereof, and thus shows more efficient effects of preventing hair loss or promoting hair growth.

Description

Aerosol-type composition that prevents hair loss or promotes hair growth

Disclosed herein is an aerosol-type composition comprising a ginseng extract that prevents hair loss or promotes hair growth.

Aerosol physically means a colloidal state comprising solid or liquid particles dispersed in a gas. In the field of beauty, many spray-type (eg hair spray) and extruded (eg hair mousse) products have been commercialized. Recently, aerosols have been widely used in skin care and cosmetic products. An aerosol composition of the related art can be found in Korean Patent Publication No. 1999-0042456.

The principle of the aerosol is to introduce the contents to be sprayed and the propellant into a sealed container of pressure resistance, and spray or extrude the contents under the pressure of the propellant. Here, depending on the type of the propellant, a liquefiable gas liquefied by internal pressure or a non-liquefiable compressible gas may be used. Moreover, different spray patterns and foaming capabilities are provided by different types of gases. Further, once the contents of the aerosol are prepared, due to the characteristics of the aerosol container, they are stored in a state of being sealed from the outside. Therefore, there is an advantage that the stability of the active ingredient can be remarkably improved, otherwise it is difficult to stabilize due to some reasons such as heat, light, and the like.

At the same time, ginseng is a well-known medicinal plant material and its function is to promote hair growth. It is known that ginseng strengthens hair roots to prevent hair loss, promote hair growth, restore hair weakened by frequent hair dyeing, perming, exposure to ultraviolet rays, and enhance hair elasticity (Journal of Dermatological Science 77 (2015) 125-134) .

According to the prior art, most products which prevent hair loss are liquid preparations which are applied to the scalp by a tube or a pump. Therefore, it has the disadvantage of being inconvenient to be used when it is applied to the scalp. In the case of an aerosol formulation containing a compressible gas such as compressible nitrogen, compressible oxygen or compressible air, the gas will escape from the formulation over time resulting in a deterioration in the sense of use.

technical problem

The technical problem to be solved by the present specification is to provide an aerosol-type composition for preventing hair loss or promoting hair growth, which comprises an aerosol stock solution containing a person who prevents hair loss or promotes hair growth as a main component and participates in the promotion. The combination of agents, such that the ginseng active ingredient can be sprayed with the gas. Technical solutions

In one general aspect, an aerosol-type composition for preventing hair loss or promoting hair growth is provided, comprising: an aerosol stock solution containing ginseng extract; and an aerosol propellant containing at least one selected from the group consisting of propane Gas, butane gas, n-butane gas, isobutane gas, pentane gas, n-pentane gas, isopentane gas, neopentane gas, liquefied petroleum gas (LPG), liquefied natural gas Liquefied gas of a group consisting of (liquefied natural gas, LNG) and dimethyl ether (DME).

According to a particular embodiment, the aerosol stock solution and the aerosol propellant are used in a weight ratio of 1:2.6-3.

According to another specific embodiment, the aerosol propellant may comprise at least one liquefied gas selected from the group consisting of propane gas, butane gas, isopentane gas, and dimethyl ether (DME).

According to still another embodiment, the aerosol propellant can comprise isopentane gas and butane gas.

According to yet another embodiment, the isopentane gas and butane gas system are used in a weight ratio of 1:7.5-8. Beneficial effect

According to a particular embodiment of the invention, an aerosol formulation is provided which provides the maximum effect of the active ingredient contained in ginseng by using a liquefied gas suitable for it. Therefore, unlike the hair loss preventing agent of the conventional liquid preparation, the aerosol preparation does not flow down when applied to the scalp to exhibit an excellent feeling of use, so that the ginseng active ingredient can remain on the scalp for a long time to increase its penetration time, and Therefore, it is more effective to prevent hair loss or promote hair growth.

Moreover, according to a specific embodiment of the present invention, an aerosol formulation having excellent foaming ability for use in an aerosol stock solution containing ginseng active ingredient is improved. Therefore, the bubble generated by the gas provides the effect of massaging the scalp and increases the permeability of the ginseng active ingredient, and thus exhibits an effect of preventing hair loss or promoting hair growth more effectively.

The specific embodiments will now be described more fully below.

In one aspect, an aerosol-type composition for preventing hair loss or promoting hair growth is provided, comprising: an aerosol stock solution containing ginseng extract; and an aerosol propellant containing at least one selected from the group consisting of propane Gas, butane gas, n-butane gas, isobutane gas, pentane gas, n-pentane gas, isopentane gas, neopentane gas, liquefied petroleum gas (LPG), liquefied natural gas (LNG) and a liquefied gas of a group consisting of dimethyl ether (DME).

In another aspect, a method of preventing hair loss or promoting hair growth comprising administering an aerosol-type composition that prevents hair loss or promotes hair growth to a body, the composition comprising: an aerosol stock solution; a sol propellant comprising at least one selected from the group consisting of propane gas, butane gas, n-butane gas, isobutane gas, pentane gas, n-pentane gas, isopentane gas, neopentane gas, Liquefied gas of a group consisting of liquefied petroleum gas (LPG), liquefied natural gas (LNG), and dimethyl ether (DME). For example, the method can comprise administering an effective amount of the composition to the skin or scalp of the individual.

In still another aspect, the use of an aerosol-type composition for preventing hair loss or promoting hair growth is provided, the composition comprising: an aerosol stock solution; and an aerosol propellant comprising at least one selected From propane gas, butane gas, n-butane gas, isobutane gas, pentane gas, n-pentane gas, isopentane gas, neopentane gas, liquefied petroleum gas (LPG), liquefied natural gas Liquefied gas of a group consisting of (LNG) and dimethyl ether (DME). For example, the composition can be applied to the skin or scalp of an individual.

In this specification, "hair loss" refers to the phenomenon of scalp hair loss or hair thinning. "Preventing hair loss" means preventing and suppressing the discovery of the image, and "promoting hair growth" means not only sprouting new hair or promoting hair germination. It also promotes the delayed transition of the growth phase to the degenerative phase during the growth cycle and promotes the healthy growth of existing hair.

The term "aerosol stock solution" means the entire content of the aerosol in addition to the propellant, and a composition containing a stock solution which is effective in preventing hair loss or promoting hair growth with ginseng as a main component.

The term "aerosol propellant" means a component capable of dispersing a content and comprising a liquefied gas, that is, an aerosol stock solution in the container.

The term "ginseng extract" contains ginseng active ingredients which are effective in preventing hair loss or promoting hair growth. The broadest concept encompasses not only the ginseng native extract but also the processed products of the extract, such as by other processing methods (including drying, concentration). , fractionation, fermentation, etc.) all types of products obtained, and have the meaning of separating specific active ingredients from ginseng itself which can effectively prevent hair loss or promote hair growth.

According to a specific embodiment, the aerosol stock solution and the aerosol propellant are used in a weight ratio of 1:2.6-3, 1:2.7-3, 1:2.8-3, 1:2.6-2.9 or 1:2.6-2.8, This makes it possible to achieve an aerosol formulation which maximizes the effect of the active ingredient contained in ginseng when applied to the scalp. Moreover, when the aerosol propellant is used in the above defined range, the composition of the smooth foam form can be sprayed and uniformly sprayed with the aerosol stock solution.

According to another specific embodiment, the aerosol propellant can comprise at least one liquefied gas selected from the group consisting of propane gas, butane gas, isopentane gas, and dimethyl ether (DME).

According to still another embodiment, the aerosol propellant comprises isopentane gas and butane gas to achieve an aerosol formulation having excellent foaming ability. Therefore, by performing the gas generated by the gas on the scalp, it is possible to provide an effective massage of the scalp and increase the permeability and penetration time of the ginseng active ingredient, thereby providing more effective prevention of hair loss or promotion of hair growth.

According to still another embodiment, the isopentane gas and the butane gas system are in a weight ratio of 1:7.5-8, 1:7.6-8, 1:7.7-8, 1:7.8-8, 1:7.5-7.9 1, 1: 7.5-7.8 or 1: 7.5-7.7, so that it can achieve an aerosol preparation that maximizes the effect of active ingredients contained in ginseng when applied to the scalp.

According to still another embodiment, the composition may comprise an aerosol stock solution, isopentane gas, and butane gas in a weight ratio of 6.5:2:15.

According to still another specific embodiment, the composition can be a cosmetic composition.

According to yet another embodiment, the composition may further comprise other ingredients conventionally used to produce hair care products comprising perfumes, solubilizers, oxime, proteins, and the like.

The aerosol formulations of the present specification can be obtained by conventional aerosol filling methods. In particular, the aerosol stock solution is directed to an aerosol container, a valve is placed on the aerosol container, a vacuum is created inside the container and air is removed from the container, crimping is performed at the appropriate location (crimping) The valve is sealed and a propellant is loaded into the container by the valve. Invention embodiment

Hereinafter, the present specification will be described in detail with reference to the embodiments. However, those skilled in the art should understand that the following examples are for illustrative purposes only and are not intended to limit the scope of the description. Example

(1) Preparation of aerosol preparations using liquefied gases

The aerosol formulations of Examples 1-3 were prepared according to the compositions shown in Table 1 below. The foaming ability of each aerosol formulation was then observed.

First, an aerosol stock solution containing ginseng extract is prepared. The ginseng extract is obtained by extracting the ginseng active ingredient, not by boiling Panax ginseng but by using Amore Pacific Co., LTD's repeated high pressure (2 kgf/cm ² ) and low pressure (0.8 kgf/cm ² ) differential pressure cycle. Method (Patent Application No.: 10-2009-0057901: System and Method for Negative and Positive Extraction). In this method, the cell wall is destroyed by the pressure difference, so that the sugar component of ginsenosides can be retained without decomposition and the extraction of the active ingredient can be maximized. In particular, the specific saponin content such as Rg1 or Re is significantly increased compared to existing extraction methods. The prepared ginseng extract is made into a liquid preparation to obtain an aerosol stock solution containing the main component of ginseng.

The aerosol stock solution is then directed to an aerosol container at room temperature and a gas is loaded into the container at a suitable ratio by a valve. After the brake was inserted, the container was shaken sufficiently to cause the contents to mix well with the gas, and the contents were sprayed for about 3 seconds on carbon paper. Then, the shape of the object to be sprayed was observed after about 10 seconds. Table 1. (Unit: g)

Fig. 1 shows the results of the foaming ability of each of (a) Example 1, (b) Example 2, and (c) Example 3. It can be seen that each formulation has excellent foaming ability. In particular, the aerosol formulation of Example 1 containing a liquefied gas (containing butane and isopentane) exhibited the highest foaming ability, i.e., foaming ability.

However, high spray pressures do not guarantee an excellent aerosol formulation. A gas is required to remain in the aerosol stock solution (ie, the contents). Example 1 In the case of using the aerosol preparation of the liquefied gas, bubbles were collected and retained in the contents, thereby providing an excellent foaming effect. Therefore, it can be seen that the aerosol-type composition for preventing hair loss or promoting hair growth of the present specification not only has excellent spray pressure but also excellent foaming ability, and thus exhibits an enhanced effect of massaging the scalp.

(2) Preparation of a composition that prevents hair loss or promotes hair growth

The aerosol stock solution of the main component of ginseng obtained by the above "(1) Preparation of an aerosol preparation" is used to obtain the aerosol preparation containing no main component of ginseng (Comparative Example 1), without the main component of ginseng, A liquid preparation of the main component of ginseng (Comparative Example 2) and an aerosol preparation containing the main component of ginseng (Example 1) were based on the composition shown in Table 2 below. This formulation was used in the following test examples. Table 2. (Unit: g)

Test example 1. Change in hair density

The compositions of Comparative Examples 1 and 2 and Example 1 were compared for their change in density with respect to each other.

The portion of the hair loss state is evaluated by the instrument and tested near the top of the head. For instrumental evaluation, subjects were allowed to rest in the waiting room for 30 minutes under constant temperature and humidity conditions of room temperature 20-25 ° C humidity 40-60% to allow the temperature and humidity of the skin surface to be applied to the test space environment. In order to measure the thickness and density of the hair, the hairline in the 1 cm diameter of the hair loss portion was uniformly cut into a length of 2 mm or less, and the central portion thereof was marked with a black dot (pattern) as a test portion. For objective determination, the investigator participated in the test and observed the same portion at each test time. The hair density measurement was performed on a predetermined area of a scalp (1 cm ² ), and the number of hairs in the area was used as an evaluation standard.

As a result, when compared with Comparative Example 1 containing no ginseng active ingredient and liquid preparation of Comparative Example 2 containing ginseng active ingredient, it can be seen from Fig. 2 that Example 1 shows a significant increase in the change in hair density. Furthermore, the composition of Example 1 showed a more significant increase in hair density when compared to Comparative Example 2 containing a large amount of ginseng active ingredient. Therefore, it can be seen that the aerosol-type composition containing the ginseng active ingredient of the present specification has an excellent effect of preventing hair loss and promoting hair growth.

Test example 2. Change in path

Each of the compositions of Comparative Examples 1 and 2 and Example 1 was compared for the change in the diameter between them.

The test conditions were evaluated as in Test Example 1 (change in hair density). The measurement of the diameter of a predetermined area of a scalp (1 cm ² ) and the average thickness of the five hairs in the area were used as the evaluation criteria.

As a result, when compared with Comparative Example 1 containing no ginseng active ingredient and liquid preparation of Comparative Example 2 containing ginseng active ingredient, it can be seen from Fig. 3 that Example 1 shows a significant increase in the change in the hair diameter. Further, the composition of Example 1 showed a more significant increase in the diameter of the hair when compared with Comparative Example 2 containing a large amount of ginseng active ingredient. Therefore, it can be seen that the aerosol-type composition containing the ginseng active ingredient of the present specification has an excellent effect of preventing hair loss and promoting hair growth.

While the invention has been shown and described, it will be understood by those skilled in the art that various modifications in form and detail may be made without departing from the scope of the invention. Accordingly, the scope of the present specification encompasses all aspects of the embodiments that fall within the spirit and scope of the appended claims.

no

Figure 1 shows the results of observation of the foaming ability of a test example, wherein (a) shows the results of Example 1, (b) shows the results of Example 2, and (c) shows the results of Example 3. Figure 2 shows the observation of the change in density of a test example. Figure 3 shows the observation of the change in the diameter of a test embodiment.

Claims (5)

An aerosol-type composition for preventing hair loss or promoting hair growth, comprising: an aerosol stock solution containing ginseng extract; and an aerosol propellant containing at least one selected from the group consisting of propane gas, butane gas, n -butane gas, isobutane gas, pentane gas, n-pentane gas, isopentane gas, neopentane gas, liquefied petroleum gas (LPG), liquefied natural gas (LNG) and dimethyl ether (DME) a group of liquefied gases. An aerosol-type composition for preventing hair loss or promoting hair growth as described in claim 1, wherein the aerosol stock solution and the aerosol propellant are used in a weight ratio of 1:2.6-3. The aerosol-type composition for preventing hair loss or promoting hair growth according to claim 1, wherein the aerosol propellant comprises at least one liquefied gas selected from the group consisting of propane gas, butane gas, isopentane gas and A group consisting of dimethyl ether (DME). An aerosol-type composition for preventing hair loss or promoting hair growth as described in claim 3, wherein the aerosol propellant comprises isopentane gas and butane gas. An aerosol-type composition for preventing hair loss or promoting hair growth as described in claim 4, wherein the isopentane gas and the butane gas system are used in a weight ratio of 1:7.5-8.