TW201625573A - 色烯酮(chromenone)抗病毒化合物、醫藥組合物及其使用方法 - Google Patents
色烯酮(chromenone)抗病毒化合物、醫藥組合物及其使用方法 Download PDFInfo
- Publication number
- TW201625573A TW201625573A TW104136779A TW104136779A TW201625573A TW 201625573 A TW201625573 A TW 201625573A TW 104136779 A TW104136779 A TW 104136779A TW 104136779 A TW104136779 A TW 104136779A TW 201625573 A TW201625573 A TW 201625573A
- Authority
- TW
- Taiwan
- Prior art keywords
- virus
- compound
- lower alkyl
- group
- fused
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D215/20—Oxygen atoms
- C07D215/22—Oxygen atoms attached in position 2 or 4
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
- C07D239/70—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings condensed with carbocyclic rings or ring systems
- C07D239/72—Quinazolines; Hydrogenated quinazolines
- C07D239/86—Quinazolines; Hydrogenated quinazolines with hetero atoms directly attached in position 4
- C07D239/88—Oxygen atoms
- C07D239/91—Oxygen atoms with aryl or aralkyl radicals attached in position 2 or 3
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
- C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D311/04—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
- C07D311/22—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 4
- C07D311/26—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 4 with aromatic rings attached in position 2 or 3
- C07D311/34—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 4 with aromatic rings attached in position 2 or 3 with aromatic rings attached in position 3 only
- C07D311/36—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 4 with aromatic rings attached in position 2 or 3 with aromatic rings attached in position 3 only not hydrogenated in the hetero ring, e.g. isoflavones
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/04—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
- C07D491/10—Spiro-condensed systems
- C07D491/107—Spiro-condensed systems with only one oxygen atom as ring hetero atom in the oxygen-containing ring
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Virology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201462123124P | 2014-11-07 | 2014-11-07 | |
US201562125647P | 2015-01-26 | 2015-01-26 | |
US201562177899P | 2015-03-25 | 2015-03-25 | |
US201562179469P | 2015-05-08 | 2015-05-08 |
Publications (1)
Publication Number | Publication Date |
---|---|
TW201625573A true TW201625573A (zh) | 2016-07-16 |
Family
ID=55909925
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
TW104136779A TW201625573A (zh) | 2014-11-07 | 2015-11-06 | 色烯酮(chromenone)抗病毒化合物、醫藥組合物及其使用方法 |
Country Status (2)
Country | Link |
---|---|
TW (1) | TW201625573A (fr) |
WO (1) | WO2016073947A1 (fr) |
Families Citing this family (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN109810063A (zh) * | 2017-11-21 | 2019-05-28 | 中国科学院上海药物研究所 | 一种新型抗流感病毒“孪药”、其制备方法及用途 |
RU2737086C2 (ru) * | 2018-10-23 | 2020-11-24 | Общество С Ограниченной Ответственностью "Валента-Интеллект" | Жидкая лекарственная форма для лечения и профилактики гриппа и орви |
CN110950828B (zh) * | 2019-11-05 | 2021-08-17 | 中国人民解放军第二军医大学 | 一种黄芩素或其衍生物、制备方法与应用 |
CA3179583A1 (fr) * | 2020-04-06 | 2021-10-14 | Humanetics Corporation | Traitement par genisteine d'une lesion pulmonaire inflammatoire |
CN112694463B (zh) * | 2020-12-16 | 2022-06-07 | 中国医学科学院医药生物技术研究所 | 一种异戊烯基色原酮类化合物在制备抗冠状病毒药物中的用途 |
FR3125047B1 (fr) * | 2021-07-06 | 2024-03-15 | Centre Nat Rech Scient | Composé de type 7a,8,9,10,11,11a-hexahydro-1H,7H-pyrano[2,3-c]xanthene, leur procédé de préparation, leurs intermédiaires et leurs applications thérapeutiques. |
CN116554137A (zh) * | 2022-01-28 | 2023-08-08 | 中国科学院上海药物研究所 | 一种环烷氨基烷氧基取代的芳基并吡喃酮类化合物及其用途 |
WO2024006287A2 (fr) * | 2022-06-27 | 2024-01-04 | University Of Kansas | Composés antiviraux utiles contre le sars-cov-2 |
Family Cites Families (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP2473495A1 (fr) * | 2009-09-18 | 2012-07-11 | Almac Discovery Limited | Composés pharmaceutiques |
-
2015
- 2015-11-06 TW TW104136779A patent/TW201625573A/zh unknown
- 2015-11-06 WO PCT/US2015/059611 patent/WO2016073947A1/fr active Application Filing
Also Published As
Publication number | Publication date |
---|---|
WO2016073947A1 (fr) | 2016-05-12 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
US20200270274A1 (en) | Anti-viral compounds, pharmaceutical compositions, and methods of use thereof | |
TW201542538A (zh) | 抗病毒化合物、醫藥組合物及其使用方法 | |
TW201625573A (zh) | 色烯酮(chromenone)抗病毒化合物、醫藥組合物及其使用方法 | |
US9408826B2 (en) | Isoflavone anti-viral compounds | |
TWI522353B (zh) | 磺醯胺抗病毒化合物 | |
US20160102099A1 (en) | Anti-viral compounds | |
EP2748172B1 (fr) | Composés anti-viraux | |
TW201202229A (en) | Anti-viral compounds | |
TW201204351A (en) | Anti-viral compounds | |
US20140199348A1 (en) | Anti-Viral Compounds | |
TW201629035A (zh) | 抗病毒化合物、醫藥組合物及其使用方法 | |
JP2013525365A (ja) | 抗ウイルス性化合物 |