TW201625558A - 磷脂醯肌醇3-激酶抑制劑 - Google Patents
磷脂醯肌醇3-激酶抑制劑 Download PDFInfo
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- TW201625558A TW201625558A TW104120373A TW104120373A TW201625558A TW 201625558 A TW201625558 A TW 201625558A TW 104120373 A TW104120373 A TW 104120373A TW 104120373 A TW104120373 A TW 104120373A TW 201625558 A TW201625558 A TW 201625558A
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- Prior art keywords
- alkyl
- dihydroquinazolin
- amino
- diamino
- phenyl
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- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
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| ES2763103T3 (es) | 2014-06-13 | 2020-05-27 | Gilead Sciences Inc | Inhibidor de la fosfatidilinositol 3-quinasa |
| JP6454736B2 (ja) | 2014-06-13 | 2019-01-16 | ギリアード サイエンシーズ, インコーポレイテッド | ホスファチジルイノシトール3−キナーゼ阻害剤 |
| BR112016028876A2 (pt) | 2014-06-13 | 2017-08-22 | Gilead Sciences Inc | composto, composição farmacêutica, método para tratar uma doença ou condição em um ser humano, kit, e, uso de um composto, um sal, isômero ou uma mistura farmaceuticamente aceitável dos mesmos. |
| CN106459005A (zh) | 2014-06-13 | 2017-02-22 | 吉利德科学公司 | 磷脂酰肌醇3‑激酶抑制剂 |
| US9944639B2 (en) | 2014-07-04 | 2018-04-17 | Lupin Limited | Quinolizinone derivatives as PI3K inhibitors |
| TWI808055B (zh) | 2016-05-11 | 2023-07-11 | 美商滬亞生物國際有限公司 | Hdac 抑制劑與 pd-1 抑制劑之組合治療 |
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| US10396145B2 (en) * | 2017-01-12 | 2019-08-27 | Micron Technology, Inc. | Memory cells comprising ferroelectric material and including current leakage paths having different total resistances |
| WO2018237007A1 (en) * | 2017-06-22 | 2018-12-27 | The United States Of America, As Represented By The Secretary, Department Of Health And Human Services | Inhibitors of phosphoinositide 3-kinase and histone deacetylase for treatment of cancer |
| CN111386264A (zh) * | 2017-07-31 | 2020-07-07 | 纽约市哥伦比亚大学理事会 | 用于治疗t-细胞急性淋巴细胞白血病的化合物、组合物和方法 |
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| US20220348558A1 (en) * | 2019-09-05 | 2022-11-03 | Wisconsin Alumni Research Foundation | Inhibitors of encephalitic alphaviruses |
| CN110590681B (zh) * | 2019-09-30 | 2021-06-01 | 中山大学 | 一种新型喹唑啉酮类化合物及其制备方法和应用 |
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| WO2015168079A1 (en) | 2014-04-29 | 2015-11-05 | Infinity Pharmaceuticals, Inc. | Pyrimidine or pyridine derivatives useful as pi3k inhibitors |
| ES2763103T3 (es) * | 2014-06-13 | 2020-05-27 | Gilead Sciences Inc | Inhibidor de la fosfatidilinositol 3-quinasa |
| CN106459005A (zh) * | 2014-06-13 | 2017-02-22 | 吉利德科学公司 | 磷脂酰肌醇3‑激酶抑制剂 |
-
2015
- 2015-06-23 MX MX2016017110A patent/MX2016017110A/es unknown
- 2015-06-23 WO PCT/US2015/037234 patent/WO2015200352A1/en not_active Ceased
- 2015-06-23 EA EA201692487A patent/EA201692487A1/ru unknown
- 2015-06-23 AR ARP150102013A patent/AR100975A1/es unknown
- 2015-06-23 BR BR112016029846A patent/BR112016029846A2/pt not_active IP Right Cessation
- 2015-06-23 NZ NZ727185A patent/NZ727185A/en not_active IP Right Cessation
- 2015-06-23 CN CN201580034671.2A patent/CN106459008A/zh active Pending
- 2015-06-23 MA MA040045A patent/MA40045A/fr unknown
- 2015-06-23 ES ES15739079T patent/ES2900812T3/es active Active
- 2015-06-23 AU AU2015280138A patent/AU2015280138B2/en not_active Ceased
- 2015-06-23 JP JP2016574424A patent/JP6391718B2/ja not_active Expired - Fee Related
- 2015-06-23 SG SG11201610341PA patent/SG11201610341PA/en unknown
- 2015-06-23 CA CA2953820A patent/CA2953820A1/en not_active Abandoned
- 2015-06-23 US US14/747,931 patent/US9765060B2/en active Active
- 2015-06-23 KR KR1020177001682A patent/KR20170015521A/ko not_active Abandoned
- 2015-06-23 EP EP15739079.0A patent/EP3160960B1/en active Active
- 2015-06-23 HK HK17105165.9A patent/HK1231474A1/zh unknown
- 2015-06-24 TW TW104120373A patent/TW201625558A/zh unknown
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2016
- 2016-12-06 IL IL249404A patent/IL249404A0/en unknown
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2017
- 2017-08-17 US US15/680,045 patent/US20180065953A1/en not_active Abandoned
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2018
- 2018-03-19 JP JP2018051249A patent/JP2018090644A/ja active Pending
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN106632077A (zh) * | 2016-10-10 | 2017-05-10 | 上海再启生物技术有限公司 | 一种2‑氨基‑4‑溴嘧啶的制备方法 |
| CN106632077B (zh) * | 2016-10-10 | 2019-01-22 | 上海再启生物技术有限公司 | 一种2-氨基-4-溴嘧啶的制备方法 |
Also Published As
| Publication number | Publication date |
|---|---|
| CN106459008A (zh) | 2017-02-22 |
| EA201692487A1 (ru) | 2017-06-30 |
| AR100975A1 (es) | 2016-11-16 |
| CA2953820A1 (en) | 2015-12-30 |
| MX2016017110A (es) | 2017-05-01 |
| BR112016029846A2 (pt) | 2017-08-22 |
| AU2015280138B2 (en) | 2018-06-14 |
| WO2015200352A1 (en) | 2015-12-30 |
| HK1231474A1 (zh) | 2017-12-22 |
| JP6391718B2 (ja) | 2018-09-19 |
| IL249404A0 (en) | 2017-02-28 |
| SG11201610341PA (en) | 2017-01-27 |
| US20160024054A1 (en) | 2016-01-28 |
| US9765060B2 (en) | 2017-09-19 |
| ES2900812T3 (es) | 2022-03-18 |
| AU2015280138A1 (en) | 2016-12-22 |
| NZ727185A (en) | 2018-04-27 |
| JP2017519021A (ja) | 2017-07-13 |
| MA40045A (fr) | 2021-06-02 |
| EP3160960B1 (en) | 2021-10-13 |
| US20180065953A1 (en) | 2018-03-08 |
| KR20170015521A (ko) | 2017-02-08 |
| EP3160960A1 (en) | 2017-05-03 |
| JP2018090644A (ja) | 2018-06-14 |
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