TW201609138A - 調節血管新生與周圍細胞組成的方法與組合物 - Google Patents
調節血管新生與周圍細胞組成的方法與組合物 Download PDFInfo
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| US10059756B2 (en) | 2006-11-02 | 2018-08-28 | Acceleron Pharma Inc. | Compositions comprising ALK1-ECD protein |
| BRPI0717964A2 (pt) | 2006-11-02 | 2013-12-17 | Acceleron Pharma Inc | Receptor e antagonistas de ligante da alk1 e usos dos mesmos. |
| CN101918022A (zh) | 2007-11-09 | 2010-12-15 | 健泰科生物技术公司 | 激活蛋白受体样激酶-1组合物及使用方法 |
| EP3398966A1 (en) * | 2008-05-02 | 2018-11-07 | Acceleron Pharma, Inc. | Methods and compositions for modulating angiogenesis and pericyte composition |
| EP2291401A2 (en) * | 2008-05-15 | 2011-03-09 | Acceleron Pharma, Inc. | Antagonists of bmp9, bmp10, alk1 and other alk1 ligands, and uses thereof |
| RU2633638C2 (ru) * | 2012-02-02 | 2017-10-16 | Акселерон Фарма Инк. | Антагонисты alk1 и их применение в лечении почечно-клеточной карциномы |
| US9809636B2 (en) | 2012-04-06 | 2017-11-07 | Acceleron Pharma Inc. | Methods for increasing red blood cell levels comprising administering BMP9 |
| HK1225740A1 (zh) * | 2013-08-22 | 2017-09-15 | Acceleron Pharma Inc. | TGF-β受体II型变体及其用途 |
| JP2016036322A (ja) * | 2014-08-11 | 2016-03-22 | 日本化薬株式会社 | 血管新生因子と結合するキメラタンパク質 |
| MA41916A (fr) * | 2015-04-06 | 2021-04-14 | Acceleron Pharma Inc | Hétéromultimères de récepteur de type i et de type ii de la superfamille de tgf-bêta et leurs utilisations |
| AU2016246602B2 (en) | 2015-04-06 | 2020-11-19 | Acceleron Pharma Inc. | Single-arm type I and type II receptor fusion proteins and uses thereof |
| CN106674352B (zh) * | 2015-11-10 | 2020-05-15 | 孙嘉琳 | 抗肿瘤蛋白内皮抑素的衍生物及应用 |
| RU2748278C2 (ru) | 2016-07-15 | 2021-05-21 | Акселерон Фарма Инк. | Композиции и способы лечения легочной гипертензии |
| JP7280182B2 (ja) | 2016-10-05 | 2023-05-23 | アクセルロン ファーマ インコーポレイテッド | バリアントＡｃｔＲＩＩＢタンパク質およびその使用 |
| CN111344306A (zh) * | 2017-11-02 | 2020-06-26 | 拜耳股份公司 | 结合alk-1和bmpr-2的双特异性抗体 |
| CN114028541A (zh) * | 2021-05-21 | 2022-02-11 | 中山大学 | Gdf2在制备改善肿瘤异常血管的药物中的用途 |
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| ATE356869T1 (de) | 1990-01-12 | 2007-04-15 | Amgen Fremont Inc | Bildung von xenogenen antikörpern |
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| US5541087A (en) | 1994-09-14 | 1996-07-30 | Fuji Immunopharmaceuticals Corporation | Expression and export technology of proteins as immunofusins |
| CA2229557A1 (en) | 1995-08-14 | 1997-02-27 | Creative Biomolecules, Inc. | Binding of osteogenic protein-i (op-1) and analogs thereof to the cell surface receptor alk-1 and analogs thereof |
| ATE214075T1 (de) | 1996-05-31 | 2002-03-15 | Health Research Inc | Monoklonale antikörper gegen endoglin und ihre verwendung in der anti-angiogenese-therapie |
| US6190660B1 (en) | 1996-05-31 | 2001-02-20 | Health Research, Inc. | Anti-endoglin monoclonal antibodies and their use in antiangiogenic therapy |
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