TW201521731A - 用於口服之脂平衡的長鏈睪固酮酯 - Google Patents
用於口服之脂平衡的長鏈睪固酮酯 Download PDFInfo
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- TW201521731A TW201521731A TW103108750A TW103108750A TW201521731A TW 201521731 A TW201521731 A TW 201521731A TW 103108750 A TW103108750 A TW 103108750A TW 103108750 A TW103108750 A TW 103108750A TW 201521731 A TW201521731 A TW 201521731A
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Classifications
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- A61K31/565—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
- A61K31/568—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol substituted in positions 10 and 13 by a chain having at least one carbon atom, e.g. androstanes, e.g. testosterone
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- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/575—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of three or more carbon atoms, e.g. cholane, cholestane, ergosterol, sitosterol
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- A—HUMAN NECESSITIES
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- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
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- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/44—Oils, fats or waxes according to two or more groups of A61K47/02-A61K47/42; Natural or modified natural oils, fats or waxes, e.g. castor oil, polyethoxylated castor oil, montan wax, lignite, shellac, rosin, beeswax or lanolin
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- A—HUMAN NECESSITIES
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- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
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Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
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- Organic Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Reproductive Health (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Gynecology & Obstetrics (AREA)
- Diabetes (AREA)
- Pregnancy & Childbirth (AREA)
- Nutrition Science (AREA)
- Physiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US13/843,403 US20130225544A1 (en) | 2009-01-08 | 2013-03-15 | Lipobalanced long chain testosterone esters for oral delivery |
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|---|---|
| TW201521731A true TW201521731A (zh) | 2015-06-16 |
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| TW103108750A TW201521731A (zh) | 2013-03-15 | 2014-03-12 | 用於口服之脂平衡的長鏈睪固酮酯 |
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| EP (2) | EP2968363B1 (enExample) |
| JP (1) | JP6307711B2 (enExample) |
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| BR (1) | BR112015020849A2 (enExample) |
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| WO (1) | WO2014145781A1 (enExample) |
| ZA (1) | ZA201507700B (enExample) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2018102618A1 (en) | 2016-11-30 | 2018-06-07 | Lipocine Inc. | Oral testosterone tridecanoate therapy |
| EP3824296B1 (en) * | 2018-07-20 | 2026-04-01 | Lipocine Inc. | Oral pharmaceutical composition comprising testosterone tridecanoate and/or testosterone dodecanoate for treating liver diseases |
| JP6945874B2 (ja) * | 2019-12-24 | 2021-10-06 | 一般財団法人バイオダイナミックス研究所 | 経口投与用医薬組成物 |
| CN115869321A (zh) * | 2021-09-28 | 2023-03-31 | 杭州中美华东制药有限公司 | 一种芦可替尼组合物及其制备方法 |
| AU2022467882B2 (en) * | 2022-06-22 | 2026-02-12 | Lipocine, Inc. | (17-)-3-oxoandrost-4-en-17-yl dodecanoate compositions and methods of preparation and use |
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| US4147783A (en) * | 1974-02-28 | 1979-04-03 | Akzona Incorporated | Oral pharmaceutical preparation |
| NL189235C (nl) * | 1974-02-28 | 1993-02-16 | Akzo Nv | Werkwijze voor de bereiding van een oraal toe te dienen farmaceutisch preparaat met androgene werking. |
| GB1567515A (en) * | 1976-05-28 | 1980-05-14 | Akzo Nv | Esters of testo-sterone and 5 -dihydro-testosterone |
| MXPA03001147A (es) * | 2000-08-23 | 2003-10-06 | Akzo Nobel Nv | Nueva formulacion de ester de testosterona para uso humano. |
| US20030022875A1 (en) * | 2001-07-27 | 2003-01-30 | Wilson Leland F. | As-needed administration of orally active androgenic agents to enhance female sexual desire and responsiveness |
| JO2505B1 (en) * | 2003-03-14 | 2009-10-05 | باير شيرنغ فارما اكتنجيسيلشافت | Pharmacy methods and formulations for obtaining acceptable serum testosterone levels |
| US7138389B2 (en) | 2004-02-09 | 2006-11-21 | University Of Washington | Oral androgen therapy using modulators of testosterone bioavailability |
| CN101217963A (zh) * | 2005-04-15 | 2008-07-09 | 克劳拉斯医疗有限公司 | 疏水性药物给药系统及含有疏水性药物的组合物 |
| US8492369B2 (en) * | 2010-04-12 | 2013-07-23 | Clarus Therapeutics Inc | Oral testosterone ester formulations and methods of treating testosterone deficiency comprising same |
| US8241664B2 (en) * | 2005-04-15 | 2012-08-14 | Clarus Therapeutics, Inc | Pharmaceutical delivery systems for hydrophobic drugs and compositions comprising same |
| US9034858B2 (en) * | 2010-11-30 | 2015-05-19 | Lipocine Inc. | High-strength testosterone undecanoate compositions |
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2014
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2015
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2016
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| AU2014232475A1 (en) | 2015-08-06 |
| MX2015010594A (es) | 2015-12-16 |
| JP6307711B2 (ja) | 2018-04-11 |
| EP2968363A4 (en) | 2016-08-17 |
| EP2968363B1 (en) | 2020-08-19 |
| US20160193227A1 (en) | 2016-07-07 |
| AU2019200097A1 (en) | 2019-01-31 |
| RU2015128028A (ru) | 2017-04-21 |
| RU2722592C2 (ru) | 2020-06-02 |
| JP2016514706A (ja) | 2016-05-23 |
| BR112015020849A2 (pt) | 2017-07-18 |
| UY35445A (es) | 2014-10-31 |
| CA2942005A1 (en) | 2014-09-18 |
| AR095538A1 (es) | 2015-10-21 |
| KR102238478B1 (ko) | 2021-04-09 |
| EP3797762A1 (en) | 2021-03-31 |
| ZA201507700B (en) | 2017-02-22 |
| IL240958B (en) | 2019-07-31 |
| WO2014145781A1 (en) | 2014-09-18 |
| AU2019200097B2 (en) | 2021-02-04 |
| IL240958A0 (en) | 2015-11-30 |
| KR20150129671A (ko) | 2015-11-20 |
| CA2942005C (en) | 2022-02-01 |
| EP2968363A1 (en) | 2016-01-20 |
| CN105073118A (zh) | 2015-11-18 |
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