200848084 v 九、發明說明： 【發明所屬之技術領域】 本案係指一種遠紅外線基材’特別是指—種_ 0 美白的遠紅外線基材。 【先雨技術】 Γ200848084 v IX. Description of the invention: [Technical field to which the invention pertains] The present invention refers to a far-infrared substrate, particularly a far-infrared substrate of the type _ 0 whitening. [First Rain Technology] Γ
C 人體的黑色素係由皮膚中黑色素細胞 (melanocytes)内之酪胺酸受酪胺酸酶催化而' 化形成，故皮膚白的人就是酪胺酸酶的功能被壓抑& 而顯得白皙，而皮膚黑的人就是酪胺酸酶作用^盛之 後的結果。一般市售的美白產品多利用化學的方^來 減少黑色素的形成，例如使用植物萃取的熊果素 但是使用化學方法來美白常存在有效成分吸收不 問題’更甚者易出現皮膚過敏不適等負面作用， 致美白的效果大打折扣。 、 =外線是波長3_1〇〇"毁米之一種電磁 波，其中波長介於3-14微米之遠紅外線，因 =物的生，有促進的效用，故科學家稱之為 以：2 f。通紅外線不但不會刺激人體，反而； 量增幅，其特性是能深入人體内部的 2生人體内細胞的水分子產生共振，賦予 進二：加速血液循環’活化新陳代謝，增 學上已證實遠紅外線對：多種？：，目前在醫 療的功效。 灵對於夕種人體疾病都有治 5 200848084 職是之故，發明人鑑於習知技術之缺 經悉心試驗與研究並一本鍥而不捨之精神，啟乃又 明出-種利料紅外線功能來達到美自： 合物與基材，以下為本發明之簡要說明。、、且 L發明内容】 Ο ϋ 本發明提供一種物理美白方式，用以解決 =利用化學方法來美白所存在之吸收不良及過敏0等 土本案之目的為提供一種遠紅外線乳霜，其包人— 遠紅祕釋放物f，該遠紅外線釋放物質的主要^八 為-乳化礦物’其中該氧化礦物包含6〇_95%之氧： 據上述構想’該遠紅外線乳霜更包含其他活 f生物貝、佐劑及添加劑。 根據上述構想，其中該遠紅外線乳霜係一化妝品 製品。 根據上述構想，其中該化妝品製品更包含至少一 種遙自於油、脂肪、壤、煙、脂肪酸、固醇、荷爾蒙、 :他命、脂肪酸醋、濕潤劑、界面活性劑、顏料、黏 ，劑、成膜劑、紫外線吸收劑、抗真菌劑、消炎 别、抗㈣、防腐劑及芳香劑之化妝品原料。 。根據上述構想，其中該遠紅外線乳霜係一醫藥製 品0 霜係一工業製 根據上述構想，其中該遠紅外線乳 6 200848084 品。 =據上述構想，其中該工業製品係選自包含油 :心!?、潤滑劑、薄膜、凝膠、紙上膠劑、乳膠、 呂化或果路材料、油墨、染料、犧及亮光劑。 2據上述構想，其中該遠紅外線釋放物質所釋 、之遠紅外線在4〜16/ζηι波長的放射係數在〇.9 以上。 Ο Ο >根據上述構想，其中該氧化礦物更包含卜讓之 氧化鐵。 一根據上述構想，其中該氧化礦物更包含丨—丨⑽之 氧化鎮。 根據上述構想，其中該氧化礦物更包含1-30%之 破酸鈣。 一本案之另一目的為提供一種遠紅外線基材，其包 含一基材以及一遠紅外線釋放物質，該遠紅外線釋放 物質混合於該基材中且其成分包含6〇-95%之氧化鋁。 根據上述構想，其中該基材係選自金屬、玻璃、 陶免及南分子材質至少其中之一。 根據上述構想，其中該遠紅外線釋放物質的成分 更包含1-20%之氧化鐵。 根據上述構想，其中該遠紅外線釋放物質的成分 更包含1-10%之氧化鎂。 根據上述構想，其中該遠紅外線釋放物質的成分 更包含1-30%之碳酸妈。 根據上述構想，其中該遠紅外線釋放物質所釋 200848084 放之退紅外線在4— 1 6 # m波長的放射係數在〇 以上。 · 根據上述構想，其中該遠紅外線釋放物質的成分 ，含氧化銘;二氧化鈦、硼化鈦、氧化鎂、氧化矽、 氧化鐵、氫氧化鋅、氧化鋅及碳化物至少其中之 〇 /才^據上述構想，其中該遠紅外線釋放物質在結構 上係選自為塊狀、顆粒狀、粉末狀及薄膜至少其中之 — 0 本案之另一目的為提供一種用於美白的組成物， 其包含一遠紅外線釋放物質，軸紅外線釋放物質的 主要成分為—氧化該組成物透過該遠紅外線釋 放物質釋放之遠紅外線達到美白的目的。 根據上述構想，更包含其他活性物質、佐劑及添 加劑。 、匕狗根據上述構想，其中該組成物係為乳液、乳霜、 ;谷液、膠體分散液、懸浮液、軟膏、洗劑、乳 箱泡床、泡床乳膠及凝膠至少其中之一。 根據上述構想，其中該組成物係一化妝品組成 物。 ，據上述構想，其中該化妝品組成物更包含至少 总種選自於油、脂肪、虫鼠、烴、脂肪酸、固醇、荷爾 豕、、隹他命、脂肪酸酯、濕潤劑、界面活性劑、顏料、 ^ =文ϋ 4、成膜劑、紫外線吸收劑、抗真菌劑、消 ^^抗/于劑、防腐劑及芳香劑之化妝品原料。 200848084 根據上述構想，其中該組成物係一醫藥組成物。 根據上述構想’其中該醫藥組成物更包含醫藥上 可接受的載劑。 根據上述構想’其中該遠紅外線釋放物質所釋 放之m紅外線在4〜1 6 “ m波長的放射係數在〇· 9 以上。 根據上述構想，其中該氧化礦物包含氧化鋁。 〇 根據上述構想，其中該氧化礦物包含60-95%之 氧化鋁。 根據上述構想，其中該氧化礦物包含丨—20%之氧 化鐵。 根據上述構想，其中該氧化礦物包含之氧 化鎂。 根據上述構想，其中該氧化礦物包含1-30%之碳 酸鈣。 1, 本案得藉由下列詳細說明，俾得更深入之了解： 【實施方式】 /本發明將藉由下述之較佳實施例及其配合之圖 示，做進一步之詳細說明。 第一實施例 本發明提供一種遠紅外線乳霜，其係將-遠紅外 線釋放物質依不同比例混入一化妝品乳霜中，較佳的 比例是化妝品乳霜中包含卜观之遠紅外線釋放物 質。該化妝品乳霜中包含油、脂肪、虫鼠、煙、脂肪酸、 9 200848084 :醇、荷爾蒙、維他命、脂肪酸酯 黏度改善劑、成膜劑乂 ^ t：,消炎劑、抗汗劑、防腐劑或芳香劑等化妝 σ 口原枓。為使該化妝品乳霜同時具有更h力效，其亦 其他"舌性物質、佐劑及添加劑。本實施例之遠 =外線乳霜經標準規範實驗證實不會引 2以此遠紅外線乳霜作為皮膚外用美白用途理應 有廣大之商機。 Ο Ο _ 2 &例巾之遠紅外線釋放物f之原料乃採 处^科技研究中心與台北醫學大學共同開發之高效 ^紅外線陶究粉末，其生物效應已經過 =相當程度之效果。其成分由數種天然礦物成 刀、、且成，其中可包含60-95%之氧化鋁、卜別％之氧 m1—1〇%之氧化鎮及1 一 3〇%之碳賴。其他成分尚 可J含二氧化鈦、硼化鈦或更多天然礦物成分，例 如氧化梦、氫氧化鋅、氧化鋅和碳化物等。以黑體當 =基準’利料紅外線光譜儀量測，該遠紅外線釋 物㈣生命光線波長範圍在6〜14微米區間具有平均 〇.98以上釋放率。且依據美國AATCC100標準方法 測j滅菌率，該釋放之遠紅外線對於金黃色葡萄 球菌及大腸桿菌都有99. 9%以上的抑菌效果。 h本實施例中之遠紅外線乳霜係一化妝品製品，其 提i、皮膚外用之塗覆以達美白、加強血液循環、促進 T代4卜、改善個人體質、進而達到保健醫療的目的。 仁疋其型式並不以此為限，其亦可為—醫藥製品或一 10 200848084 工某製品。 若本發明所提供之遠紅外 品，其可作為油漆、塗料 ^相係為一工業製 上膠劑、乳膠、營造或準路劑、缚膜、凝膠、紙 亮光劑等。只要處於有該此工二油墨、染料、蠟及 以得到遠紅外線帶给人體：面；衣品的環境中，就可 目了應用及影響之層面之廣由此可見一班。 Ο Ο 二貫施你h 請參閱第一圖，盆盘士义 的第二較佳實施例之示音3本tr提遠紅外線基材 紅外線基材包含一“圖20。如圖*，本發明之遠 .^, L 基材20以及混合於該基材中 放物f10。其中該基材2〇係選自 玻璃、陶瓷及高分子材質至少其中之一。該遠 紅外線釋放物質10在結構上丰 人' ^ Φ ^ IZ -. 霉上係k自為塊狀、顆粒狀、 =狀及雜至少其巾之—。該遠紅外 =他性質如成分及功效等皆同於第一實施例，故此 +再複述。 該遠紅外線基材可應用的範圍十分廣泛，尤 ^為了吳白之用途，該遠紅外線基材可做成曰常 J活中的各種器具、醫療訂口、建材、交通工呈 或紡織品’以達到隨時隨地都可美白的便利性。 复三實施例 本發明的第三實施例為一種用於美白的組成物， 11 200848084C The melanin of the human body is formed by the tyrosine acid in the melanocytes in the skin, which is catalyzed by tyrosinase, so the white-skinned person is the function of the tyrosinase being suppressed & The person with dark skin is the result of the action of tyrosinase. Generally, commercially available whitening products use chemical methods to reduce the formation of melanin, for example, using plant-derived arbutin, but using chemical methods to whiten often there is no problem in the absorption of active ingredients, and even more susceptible to skin allergies and other negative effects, The effect of whitening is greatly reduced. , = the outer line is a wavelength of 3_1 〇〇 " an electromagnetic wave of ruined rice, where the wavelength of the infrared rays of 3-14 microns, because of the birth of the object, has a promoting effect, so scientists call it: 2 f. Infrared rays will not only stimulate the human body, but instead; the increase in amplitude is characterized by the resonance of water molecules that can penetrate deep into the body of the human body, and the second is to accelerate the blood circulation to activate the metabolism, and the far infrared rays have been confirmed on the growth. Yes: Multiple? : The current efficacy of medical treatment. The spirit has a cure for the human disease of the night. 200848084 The position of the inventor is that the inventor has carefully tested and researched the ins and outs of the spirit of the prior art, and he has also revealed that the infrared function of the material is used to achieve beauty. From the following: a composite and a substrate, the following is a brief description of the invention. The invention provides a physical whitening method for solving the problem of using the chemical method to whiten the malabsorption and allergies, etc. The purpose of the present invention is to provide a far-infrared cream, which is packaged. — far red secret release substance f, the main component of the far-infrared emitting substance is - emulsified mineral 'where the oxidized mineral contains 6 〇 95% of oxygen: According to the above concept, the far-infrared cream contains other living creatures Shell, adjuvant and additives. According to the above concept, the far-infrared cream is a cosmetic product. According to the above concept, wherein the cosmetic product further comprises at least one of oil, fat, earth, tobacco, fatty acid, sterol, hormone, vitamins, fatty acid vinegar, humectant, surfactant, pigment, adhesive, Cosmetic raw materials for film formers, UV absorbers, antifungals, anti-inflammatory, anti-(four), preservatives and fragrances. . According to the above concept, the far-infrared cream is a pharmaceutical product, and the industrial system is based on the above concept, wherein the far-infrared emulsion 6 200848084 product. = According to the above concept, wherein the industrial product is selected from the group consisting of oils: lubricants, lubricants, films, gels, paper sizing agents, latexes, scented or fruit materials, inks, dyes, and glazing agents. 2 According to the above concept, the far-infrared rays emitted by the far-infrared emitting material have an emission coefficient of 〇.9 or more at a wavelength of 4 to 16/ζη. Ο Ο > According to the above concept, the oxidized mineral further contains iron oxide. According to the above concept, the oxidized mineral further comprises an oxidized town of ruthenium-osmium (10). According to the above concept, the oxidized mineral further contains 1-30% of calcium sulphate. Another object of the present invention is to provide a far infrared ray substrate comprising a substrate and a far infrared ray releasing substance mixed in the substrate and having a composition comprising 6 〇 to 95% of alumina. According to the above concept, the substrate is selected from at least one of a metal, a glass, a ceramic, and a southern molecular material. According to the above concept, the component of the far-infrared emitting substance further contains 1-20% of iron oxide. According to the above concept, the component of the far-infrared emitting substance further contains 1-10% of magnesium oxide. According to the above concept, the component of the far-infrared emitting substance further contains 1-30% of a carbonic acid mother. According to the above concept, in which the far-infrared emitting material is released, 200848084, the radiation coefficient of the infrared ray at the wavelength of 4 - 16 # m is above 〇. According to the above concept, wherein the component of the far-infrared emitting substance contains oxidized crystal; at least one of titanium dioxide, titanium boride, magnesium oxide, cerium oxide, iron oxide, zinc hydroxide, zinc oxide and carbide The above concept, wherein the far-infrared emitting material is structurally selected from the group consisting of a block, a granule, a powder, and a film at least - 0. Another object of the present invention is to provide a composition for whitening, which comprises a far The infrared ray releasing substance, the main component of the shaft infrared ray releasing substance, is for oxidizing the far infrared ray released by the composition through the far infrared ray releasing material to achieve the purpose of whitening. According to the above concept, other active substances, adjuvants and additives are further included. According to the above concept, the hyena is at least one of an emulsion, a cream, a gluten solution, a colloidal dispersion, a suspension, an ointment, a lotion, a blister bed, a blister latex, and a gel. According to the above concept, the composition is a cosmetic composition. According to the above concept, wherein the cosmetic composition further comprises at least a total species selected from the group consisting of oil, fat, pest, hydrocarbon, fatty acid, sterol, hydrazine, vitamins, fatty acid esters, humectants, interfacial activity. Agents, pigments, ^ = ϋ 4, film-forming agents, UV absorbers, anti-fungal agents, anti-anti-agents, preservatives and fragrances of cosmetic raw materials. 200848084 According to the above concept, wherein the composition is a pharmaceutical composition. According to the above concept, wherein the pharmaceutical composition further comprises a pharmaceutically acceptable carrier. According to the above concept, the m-infrared rays emitted by the far-infrared emitting substance have an emissivity of 〇·9 or more at a wavelength of 4 to 16 6 m. According to the above concept, the oxidized mineral contains alumina. 〇 According to the above concept, The oxidized mineral comprises 60-95% alumina. According to the above concept, wherein the oxidized mineral comprises cerium - 20% iron oxide. According to the above concept, wherein the oxidized mineral comprises magnesium oxide. According to the above concept, wherein the oxidized mineral Containing 1-30% of calcium carbonate. 1. The present invention will be further understood by the following detailed description: [Embodiment] The present invention will be illustrated by the following preferred embodiments and their cooperation. The present invention provides a far-infrared ray cream which mixes the far-infrared ray releasing material into a cosmetic cream in different proportions, and a preferred ratio is that the cosmetic cream contains Far infrared ray release substance. The cosmetic cream contains oil, fat, worm, smoke, fatty acid, 9 200848084: alcohol, hormone, vitamin, fat Acidity viscosity improver, film-forming agent ,^t:, anti-inflammatory agent, anti-perspirant, preservative or fragrance, etc. In order to make the cosmetic cream have more effect, it is also other " Tongue substance, adjuvant and additive. The far-outer line cream of this embodiment has been confirmed by standard normative experiments, and it is not possible to introduce 2 far-infrared cream as a skin for external use. There should be a lot of business opportunities. Ο Ο _ 2 & The raw material of the far-infrared emitting material f of the towel is the high-efficiency ^ infrared ceramic powder jointly developed by the Science and Technology Research Center and the Taipei Medical University. The biological effect has been passed to a considerable extent. The composition consists of several natural minerals. It can be formed into a knife, a mixture, and can contain 60-95% of alumina, %% of oxygen, m1 -1%% of oxidized town and 1-3% of carbon lag. Other components can still contain titanium dioxide, boron Titanium or more natural mineral components, such as oxidized dreams, zinc hydroxide, zinc oxide and carbides, etc. The black body is used as a reference d-infrared spectrometer, and the far-infrared release (4) has a lifetime light wavelength range of 6~ 14 micron interval The release rate is above 98. And the sterilizing rate is measured according to the American AATCC100 standard method, and the released far infrared ray has a bacteriostatic effect of more than 99.9% for both Staphylococcus aureus and Escherichia coli. Far-infrared cream is a cosmetic product, which is applied to the skin for external whitening, strengthens blood circulation, promotes T generation, improves personal physique, and then achieves the purpose of health care. To be limited to this, it can also be a pharmaceutical product or a product of 10200848084. If the far infrared product provided by the present invention can be used as a paint, coating, or an industrial sizing agent, latex, construction or Proximity agent, binding film, gel, paper polish, etc. As long as there is an ink, a dye, a wax and a far infrared ray to the human body: the surface of the clothing; the environment can be seen in a wide range of applications and influences. Ο Ο Ο 你 h h h h h h h h 请 请 请 请 请 请 请 请 请 请 请 请 请 请 请 请 请 请 请 请 请 请 请 请 请 请 请 请 请 请 请 请 请 请The substrate 20 is mixed with the substrate f10 in the substrate, wherein the substrate 2 is selected from at least one of glass, ceramic and polymer materials. The far infrared ray releasing material 10 is structurally丰人' ^ Φ ^ IZ -. The mildew k is self-blocking, granular, = and mixed with at least its towel. The far infrared = his properties such as composition and efficacy are the same as in the first embodiment. Therefore, the re-infrared substrate can be applied in a wide range, especially for the purpose of Wu Bai, the far-infrared substrate can be made into various appliances, medical ordering, building materials, transportation or The textile 'can achieve the convenience of whitening anytime and anywhere. The third embodiment of the present invention is a composition for whitening, 11 200848084
° ^遠紅外線釋放物質，該遠紅外線釋放物質的 其：性質如成分及功效等皆同於第一實施例，故此不 再稷述。該組成物透過該遠紅外線釋放物質釋放之遠 紅外線達到美自的目的。本實施例巾之美白組成物可 包含其，活性物質、佐劑及添加劑以達到更多之功 效。本貫施例之美白組成物可以各種形式呈現，例如 乳液、乳冑、凝膠、溶液、膠體分散液、懸浮液、軟 貧、洗劑、乳霜、泡沫、泡沫乳膠或凝膠等。若該挺 合物添加於化妝品當中，則該化妝品可包含油、脂肪、 紙烃月曰肪g文、固醇、荷爾蒙、維他命、脂肪酸酯、 濕潤劑、界面活性劑、_、黏度改善劑、成膜劑、 =吸:導抗真菌劑、消炎劑、抗汗劑、防腐劑 方曰劑等化妝品原料。若該組合物用於醫藥上，則 =醫藥用的組合物可包含醫藥上可接受的載劑、賦形 劑或稀釋劑，使其經各種途㈣於美白用途。 土 八b)，其揭露本發明所提供之 通紅外線釋放物質對B1義細胞中黑色素含量影塑 =狀圖。本試驗是以B16刚黑色素瘤細胞做為試ς 取每盤含1Q4個⑽刚黑色素瘤細胞的細胞培 二：3、7培養24小時。之後分別將細胞培養盤置 、00么克的遠紅外線釋放物質（實驗組）及100公 上，使細胞與遠紅外線釋放物質無直 妾，觸’置放24及48小時之後收集細胞，將細胞穿 j以分光光度計測定波長475 nm之吸 胞中黑色素含量的代表。如圖中所示，以本發明戶Ϊ提 12 200848084 供之遠紅外線釋放物質處理B16F10細胞24小時後可 有效降低B16F10細胞中黑色素含量達10%;在處理48 小時後黑色素含量則可降低15%。由本試驗可知本發明 所提供之遠紅外線釋放物質確實可降低細胞中黑色素 的含量。 請參閱第三圖（a) (b)，其揭露本發明所提供之 遠紅外線釋放物質對B16F10細胞體外生長的影響之 柱狀圖。本試驗同樣是以B16F10黑色素瘤細胞做為試 f、 驗材料，取每盤含1〇4個B16F10黑色素瘤細胞的細胞 培養盤培養16小時。之後分別將細胞培養盤置於100 公克的遠紅外線釋放物質（實驗組）及100公克的奶粉 (對照組）上處理24及48小時。處理後的B16F10黑色 素瘤細胞以 MTT (3，[4,5-dimethylthiazol-2-yl]-2,5_ diphenyltetrazolium bromide)測定法檢測細胞於體外增 殖的情形。如圖中所示，以本發明所提供之遠紅外線 釋放物質處理B16F10細胞24小時和48小時，都有抑 U 制B16F10細胞增殖的效果。 請參閱第四圖（a)(b)，其揭露本發明所提供之 遠紅外線釋放物質對B16F10細胞酪胺酸酶活性的影 響之柱狀圖。本試驗同樣是以B16F10黑色素瘤細胞做 為試驗材料，取每個孔洞包含104個B16F10黑色素瘤 細胞的6孔細胞培養盤培養16小時。之後分別將細胞 培養盤置於100公克的遠紅外線釋放物質（實驗組）及 100公克的奶粉（對照組）上處理24小時。以胰蛋白酶 使處理後的B16F10黑色素瘤細胞自細胞培養盤中脫 13 200848084 落並收集該些處理後的細胞，之後以酵素連結免疫吸 附測疋（enzyme_linked immunosorbent assay, ELISA)之 測定法檢測細胞中酪胺酸酶的活性。如圖中所示，酪 私1 S#的活性以波長650 nm及370nm之吸光值做為 代表’以本發明所提供之遠紅外線釋放物質處理 B16F10細胞24小時，確實有抑制B16F1〇細胞中酪胺 酸酶活性的效果。因酪胺酸酶是合成黑色素前趨物的° ^ Far-infrared emitting material, the properties of the far-infrared emitting material: properties such as composition and efficacy are the same as in the first embodiment, and therefore will not be described again. The composition is passed through the far-infrared rays released by the far-infrared emitting material to achieve the purpose of beauty. The whitening composition of the towel of this embodiment may contain active ingredients, adjuvants and additives to achieve more utility. The whitening compositions of the present examples can be presented in a variety of forms such as lotions, nipples, gels, solutions, colloidal dispersions, suspensions, soft, lotions, creams, foams, foams or gels. If the conjugate is added to the cosmetic, the cosmetic may comprise oil, fat, paper hydrocarbon, sterol, hormone, vitamin, fatty acid ester, humectant, surfactant, _, viscosity improver , film-forming agent, = suction: anti-fungal agent, anti-inflammatory agent, anti-perspirant, preservative prescription and other cosmetic raw materials. If the composition is for pharmaceutical use, the pharmaceutical composition may comprise a pharmaceutically acceptable carrier, excipient or diluent for various purposes (4) for whitening purposes. Earth 8 b), which discloses the infrared-emitting substance provided by the present invention, which is a graph of the melanin content in B1 cells. In this test, B16 melanoma cells were used as a test. Cells containing 1Q4 (10) melanoma cells per plate were cultured for 24 hours. Then, the cell culture plate was placed, 00 gram of far-infrared emitting material (experimental group) and 100 liters, so that the cells and the far-infrared emitting substance were not directly licked, and the cells were collected after 24 and 48 hours of placement, and the cells were collected. A representative of the melanin content in the cell at a wavelength of 475 nm was measured by a spectrophotometer. As shown in the figure, the treatment of B16F10 cells with the far-infrared emitting material provided by the present invention 12200848084 can effectively reduce the melanin content in B16F10 cells by 10% after 24 hours; the melanin content can be reduced by 15% after 48 hours of treatment. . It is known from the test that the far-infrared emitting substance provided by the present invention can actually reduce the content of melanin in the cells. Referring to Fig. 3(a)(b), there is shown a histogram of the effect of the far infrared ray releasing substance provided by the present invention on the growth of B16F10 cells in vitro. In this test, B16F10 melanoma cells were also used as test materials, and culture plates containing 1〇4 B16F10 melanoma cells per plate were cultured for 16 hours. The cell culture plates were then placed on a 100 gram far infrared ray release material (experimental group) and 100 gram of milk powder (control group) for 24 and 48 hours, respectively. The treated B16F10 melanoma cells were assayed for proliferation in vitro by MTT (3,5-dimethylthiazol-2-yl]-2,5-diphenyltetrazolium bromide assay. As shown in the figure, treatment of B16F10 cells with the far infrared ray releasing substance provided by the present invention for 24 hours and 48 hours all had the effect of inhibiting the proliferation of B16F10 cells. Referring to Figure 4(a)(b), there is shown a bar graph of the effect of the far infrared ray releasing material provided by the present invention on B16F10 cell tyrosinase activity. In this test, B16F10 melanoma cells were also used as test materials, and 6-well cell culture plates containing 104 B16F10 melanoma cells per well were cultured for 16 hours. The cell culture plates were then placed on a 100 gram far infrared ray release material (experimental group) and 100 gram of milk powder (control group) for 24 hours. The treated B16F10 melanoma cells were removed from the cell culture tray by trypsin and collected, and the treated cells were collected, and then detected by an enzyme-linked immunosorbent assay (ELISA) assay. Tyrosinase activity. As shown in the figure, the activity of tyrosine 1 S# is represented by the absorbance at wavelengths of 650 nm and 370 nm. The treatment of B16F10 cells with the far-infrared emitting material provided by the present invention for 24 hours does inhibit the inhibition of B16F1 〇 cells. The effect of aminase activity. Tyrosinase is a synthetic melanin precursor
Ο 重要酵素，故若該酵素受到抑制，將使黑色素的形成 受到顯著的抑制。 、本愈明所採用的遠紅外線釋放物質成分來源 ，天然礦物成分，經儀器檢測不但有壓電位性負 離子發放，且檢測不出游離輻射。目前游離輻射 仍普遍被認為具有造成人體基因冑變並致癌的危 險性’而很乡利遠紅外線產品為提高產品中遠 紅外線的放射係數，添加過量之稀有元素，以致使 用者暴露在過量游離輻射中而不自知。本發明不但且 ^很高的遠紅外線放㈣數，且亦沒㈣離㈣的疑 慮。所以本發明的應用產&，尤其是肖 與人體攝取食品水分相社產品，皆十分健康安^。疋 惟以上所述僅為本發明之較 此即拘限本發明之專利筋鬥孕乂佺只靶例，非據 說明書及圖示内容所為之等效結構變化者，:同 理包含於本發明之範圍内，合予陳明。：σ 【圖式簡單說明】 14 200848084 第一圖：本發明之遠紅外線基材的較佳實施例之 示意圖； 第二圖（a)(b):本發明之遠紅外線釋放物質對 B16F10細胞中黑色素含量影響之柱狀圖； 第三圖（a)(b) ··本發明之遠紅外線釋放物質對 B16F10細胞體外生長的影響之柱狀圖；及 第四圖（a)(b):本發明之遠紅外線釋放物質對 B16F10細胞酪胺酸酶活性的影響之柱狀圖。 Γ' 【主要元件符號說明】 10遠紅外線釋放物質 20基材 15Ο An important enzyme, so if the enzyme is inhibited, the formation of melanin will be significantly suppressed. The source of the far-infrared emitting material used by Ben Yuming, the natural mineral component, not only the piezoelectric negative ions are emitted by the instrument, but also the free radiation is not detected. At present, free radiation is still generally considered to have the risk of causing genetic mutation and carcinogenesis of the human body. However, the far-infrared products of the town are far-increasing to increase the radioactivity of far-infrared rays in the product, and add excessive rare elements, so that the user is exposed to excessive free radiation. Without knowing it. The present invention not only has a high number of far-infrared rays (four), but also has no doubts about (four) from (four). Therefore, the application of the present invention &, especially the consumption of moisture and food products by the human body and the human body, are very healthy.以上 以上 以上 以上 以上 以上 以上 以上 以上 以上 以上 以上 以上 以上 以上 以上 乂佺 乂佺 乂佺 乂佺 乂佺 乂佺 乂佺 乂佺 乂佺 乂佺 乂佺 乂佺 乂佺 乂佺 乂佺 乂佺 乂佺 乂佺 乂佺 乂佺 乂佺 乂佺 乂佺 乂佺 乂佺 乂佺 乂佺 乂佺 乂佺 乂佺 乂佺Within the scope of the agreement, Chen Ming. : σ [Simple Description of the Drawings] 14 200848084 First: Schematic diagram of a preferred embodiment of the far-infrared substrate of the present invention; Second Figure (a) (b): The far-infrared emitting substance of the present invention is in B16F10 cells Bar graph of the influence of melanin content; Fig. 3 (a) (b) · Bar graph of the effect of the far infrared ray releasing substance of the present invention on the growth of B16F10 cells in vitro; and Fig. 4 (a) (b): A histogram of the effect of the far-infrared emitting material of the invention on the tyrosinase activity of B16F10 cells. Γ' [Major component symbol description] 10 far infrared ray release material 20 substrate 15