TW200819430A - Enhanced mucosal hydration and mucosal clearance by treatment with sodium channel blockers and osmolytes - Google Patents

Info

Publication number

TW200819430A

TW200819430A TW096133635A TW96133635A TW200819430A TW 200819430 A TW200819430 A TW 200819430A TW 096133635 A TW096133635 A TW 096133635A TW 96133635 A TW96133635 A TW 96133635A TW 200819430 A TW200819430 A TW 200819430A

Authority

TW

Taiwan

Prior art keywords

chor8

het

independently

nr13r13

conr7

Prior art date

2006-09-07

Links

• Espacenet
• Global Dossier
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• 230000036571 hydration Effects 0.000 title claims abstract description 12
• 238000006703 hydration reaction Methods 0.000 title claims abstract description 12
• 238000011282 treatment Methods 0.000 title claims description 44
• 230000000065 osmolyte Effects 0.000 title abstract 2
• 239000000203 mixture Substances 0.000 claims abstract description 110
• 238000000034 method Methods 0.000 claims abstract description 56
• 229940125794 sodium channel blocker Drugs 0.000 claims abstract description 38
• 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 claims abstract description 29
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• 230000000420 mucociliary effect Effects 0.000 claims abstract description 9
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• 125000004122 cyclic group Chemical group 0.000 claims description 212
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• 150000001875 compounds Chemical class 0.000 claims description 203
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• 239000002076 α-tocopherol Substances 0.000 description 1
• 235000004835 α-tocopherol Nutrition 0.000 description 1