TW200812490A - Active compound combinations having insecticidal properties - Google Patents

Abstract

The present invention relates to novel active compound combinations comprising at least one known compound of the formula (I) in which R is as defined in the description, and at least one further active compound, for example from the class of the benzoylureas or the chitin synthesis inhibitors or other classes, which combinations are highly suitable for controlling animal pests such as insects and/or mites.

Description

200812490 IX. INSTRUCTIONS OF THE INVENTION: TECHNICAL FIELD OF THE INVENTION The present invention relates to novel active compound combinations comprising, firstly, at least one compound of formula (I) known, and secondly, at least one other active compound of the other five classes For example, from phenylhydrazine ureas or chitin synthesis inhibitors, or the like, such compositions are highly suitable for use in the prevention of organisms such as insects and/or worms. [Prior Art] 10 Compounds of formula (I) are known

Wherein R represents a thiol or cyclopropyl group having insecticidal activity (Reference: EP-A 0 539 588), specifically, the related compounds are compounds (la) and (lb):

200812490

In addition, certain insect growth inhibitors are known to have insecticidal action, including, for example: a) phenylhydrazinoureas, such as ίο 1 chlorfluazuron (known from: DE- A 28 18 830)

15 2. Difhibenzuron (learned from: DE-A21 23 236)

3. Lufenuron (learned from: EP-A 0 179 022)

4.Teflonzuron (learned since ·· EP_A 0 052 833) 200812490

5 5. Triflumuron (learned from: DE-A 26 01 780)

10 6·novahiron (learned from: US 4,980,376)

7. Hexaflumuron (available from: EP-A 0 071 279) 15

20 8. Bistrifluron (DBI-3204) (Know from: WO 98/00394)

200812490 9·Flufenoxuron (learned from: ΕΡ-Α 0 161 019)

5 10·flucycloxuron (known from: R Schdtes, /LW· Hofinan, A.C. Grosscurt, BCPC Conf· Pests Dis· 1988, 2, 559-666)

10

Ci 11 · polyfluorourea (noviflumuron) (obtained from: WO 9819542A1, 1998)

15 12·buprofezin (learned from: Price Pro/ Conf - Pests Dis., 1981, 1, 59)

Ch3 -9- 20 200812490 b) Chitin synthesis inhibitors, for example 13. Cyromazine (known from: GB-A 1 587 573)

10 c) Infant hormone mimetic agents, such as 14·Bilibifene (j>yriproxifen) (from: gb_A2 140 010)

d) molting hormone stimulants, such as 15 · tebufenozide (available from: US 4,985,461)

16·Mentfenozide (learned from: us 5 344,958) 200812490

e) additionally 17·Croatfenozide (known from: EP 00496342)

10

18. Chlorofonozide (available from: EP 228 564)

19. Difenolan (learned from: DE 2 65 5 910)

-11 - 200812490 20·fenoxycarb (learned from: EP4334)

SUMMARY OF THE INVENTION P is surprisingly the insecticidal activity of the active compound combinations according to the invention is much higher than the sum of the activities of the individual active compounds, there is an unanticipated true synergy Sexual effects, and not just the addition of activity. In addition to at least one active compound of the formula (I), the active compound combinations according to the invention comprise at least one compound which is individually listed in the above 1 to 20. Preferably, the active compound combination according to the invention comprises an active compound of one of formula (la) or (lb) A and an insect growth regulator of 1 to 20 which are individually listed above. The combinations listed in Table 1 are in accordance with preferred embodiments of the present invention. 20 Table 1 Mixture containing the compound of formula (I) Additional active compound-12- 200812490 1· Ia and 1 chlorfluazuron 2. la and 2 diflubenzuron 3· Ia and 3 Lufenlong ( Lufenuron) 4. la and 4 teflubenzuron 5. Ia and 5 triflumuron 6. Ia and 6 novalon (novaluron) 1. Ia and 7 hexafhmuiron 8· Ia and 8 bistrifluoron 9. Ia and 9 flufenoxuron 10· Ia and 1 flueycloxuron 11. Ia and 11 polyflurane (noviflumuron) 12. Ia and 12 Bufenfen (buprofezin) 13· Ia and 13 cyromazine 14· la and 14 bailipfen (@}^|>1*0\^'611) 15. Ia and 15 tefeno (tebufenozide) 16 · la and 16 methoxyfenozide 17. la and 17 ringworms (〇1^〇11^&11(^(1) 18· Ia and 18 halofenozide 19· Ia and 19 diofenolan 20. la and 20 fenoxycarb In addition, the various combinations listed in Table 2 are also preferred embodiments according to the invention. -13 - 2008 12490 Table 2 Mixture containing the compound of formula (I) Additional active compound 1. Ib and 1 chlorfluazuron 2. lb and 2 diflubenzuron 3· Ib and 3 lufenuron 4· Ib and 4 tefhibenzuron 5. Ib and 5 triflimuiron 6. Ib and 6 novalon (novaluron) 7· Ib and 7 hexafhmiuron 8. Ib and 8 double Sanfu Bistrifluoron 9. Ib and 9 are flufenoxuron 10. Ib and 1 flueycloxuron 11· Ib and 11 fluorofenuron 12. Ib and 12 buprofezin 13 Ib and 13 cyromazine 14. Ib and 14 pyriproxifen 15· Ib and 15 tebufenozide 16. Ib and 16 methoxyfenozide 17; Ib and 17 Chromafenozide 18. Ib and 18 halofenozide 19. Ib and 19 difenenolan 20. Ib and 20 fenoxycarb -14- .200812490彳 is according to the present invention, the riding compound combination exists in the presence of a certain amount of activation (4), however, The weight between the active compounds in the real estate can be relatively high, and in general, according to the invention, the combination of the formula _activated two from the human to the 2G insect growth regulators is preferred and special. The best mixing ratio is: The preferred mixing ratio: 125·· 1 to! : 125 Particularly good mixing ratio: 25 : 1 to 1: 25 10 15 The ratio of this s is based on the proportion of heavy summer. This ratio is understood to mean the active compound of (I) insect growth regulator. The active compound combination of the present invention, in combination, the plant has good aftertaste and is beneficial to Wenjin animals, and can endure the environment well, and is suitable for providing protective plants and Plant organs, for increased yield, for improving the quality of harvests and for controlling pests, especially with agriculture, horticulture, animal husbandry, forestry, garden and leisure facilities, storage of products and materials, and sanitation In the field of related insects, mites, worms, nematodes and mollusks, they should be used as a plant protection agent, they are active against normal sensitive and resistant species, and against all of them. Or at various stages of development, the above-mentioned pests include: Anoplura (Phthiraptera) organisms, for example, Damcdinia spp. 'Haematopinus spp., long genus (Unognathus spp.) , pedicuis spp., Trichodectes spp. -15· 20 200812490 10 15 Arachnida creatures, for example, scorpion scorpion (dcarws illusion > 〇 , , , , , , 蜱 / / / / / / / / / ( ( ( ( ( ( ( ( ( ( ( ( dc dc dc dc dc dc dc dc /ops *ψρ·),jcw/ws spp·, 蜱 以 ? / Arg Arg Arg Arg Arg Arg Arg Arg Arg Arg Arg Arg Arg Arg Arg Arg Arg Arg Arg Arg Arg Arg Arg Arg Arg Arg Arg Arg Arg Arg Arg Arg Arg Arg Arg Arg Arg Arg Arg Arg Arg Arg Arg Arg Arg Arg Arg Arg Arg Arg Arg Arg ), tyo moth (Bryobia praetiosa), genus Chorioptes spp., chicken skin worm (CDerwfl^yMws gallinae), worm known as spider mites (five oieirimyc/zws spp·), jujube leaves, brown leafhopper Eutetranychus spp., Eriophyes spp., Eriophyes spp., Hemitarsonemus spp., genus s/7/7·), hard genus (/xodes πρ. ), black widow ball spider (JLatrodectus mactans) hA knows [Metatetranychus spp·), leaf butterfly {Oligonychus spp,, Ornithodoros spp, winter work or (Pcmonychus spp.), transfer money moth ( Phyllocoptruta oleivorcf), pha茶夤, Polyphagotarsonemus latus), Psoroptes spp·, Rhipicephalus spp, Rhizoglyphus spp,瞒 genus (Sarcoptes 羽!?·), 峨子 maurus), Stenotarsonemus spp·, Tarsonemus spp., Tetranychus spp. ^ Vasates lycopersici o Bivalva For example, the Drezbe·Chilopoda creature, for example, the genus Geo/?/n7i^ spp., Scutigera spp. Coleoptera, for example, bean bean o&eciws), long golden tortoise spp·), eucalyptus euphorbia ("ge/<3 side 'ca α/m·), golden worm armor r/o milk sp;?.), potato 鳃金龟-16- 20 200812490 (Amphimallon solstitialis), like Anobium punctatum, l Anoplophora spp., posture qi {Anthonomus spp.) , I 蠹 (』 /? 伙 re 胆6^/?/?·), A total chafer (for (10) guest (10) / "spp ·), cryptic armor (Atomaria spp.), black, anti-stupid { Attagenus spp·), Bruchidius obtectus, l genus (Bruchus spp., ill (Ceuthorhynchus spp., Cleonus mendicus, Conoderus spp., stalk-like nasal bombing ([〇〇/?〇//如如Sp/λ), grasshopper (Co vs. zealandica), $^Curculio spp, field dry KCryptorhynchus lapathi), Dermestes spp., Diabrotica ίο spp. Epilachna spp., Epilachna spp.

Faw persuades >7 like cwke, naked pearl 曱 (G7 from z'wm; 76^//〇/do 5), African unicorned {Heteronychus arator), Hylamorpha elegans, 3 匕美家天牛 (//less /oirwpa q/w/ws), 象叶象甲, 咖徘果蠹{Hypothenemus spp.), Lachnostrna is consanguinea, Colorado golden worm (jLep 伽οΜπα decemlineata) ), H ® worm (Zfxws spp·), brown scorpion spp.), MeUgethes aeneus, Melonontha melolontha, owing to the afternoon, Migdolus spp·, Tiannian { Monochamus spp·,, Naupactus xanthographus, Niptus /zo/o/ewcws, rhinoceros, M (Oryzaephilus surinamensis), black 萄 ϋ ϋ Otiorrhynchus • sw/caiws), small blue-and-white golden tortoise (〇xj; ceion/a, horseradish leafhopper {Phaedon cochleariae), gold l + (Phyllophaga spp.), B principal gold • 17- 200812490 elephant (Popillia japonica) , Premnotrypes spp·, 茱i 跳 1f (Psylliodes chrysocephala), bead genus {P Tinus spp·), Rhizobius ventralis, family XRhizopertha dominica), I play {Sitophilus spp.), Wo I, (Sphenophorus spp.), Sternechus 5 spp·, Symphyletes spp, XTenebrio molitor, Wei Tribolium spp., Trogoderma spp., (Tychius, genus Zjv/oirec/zw π/?·, modulo step spp·). Collembola creatures, for example, worms ίο armatus) ° Dermaptera creatures, for example, European cockroaches (For/icw/β auricularia) ° Diplopoda creatures, for example, with zebra land (B/amw/ws guttulatus) 〇15 Diptera (Diptera), for example, Aedes *y/7/7.), by I (Anopheles spp.), Hete Mao (Bibio hortu! Anus), red-headed 1 fly (Ca///p/zom eaiAracep/m/fl), Mediterranean fruit fly (CerflizYk, big-headed golden rope print/?·), spiral rope (Cochliomyia spp.) (Cor Office / ο~·β 2〇cmthropophaga), Cuiex spp., Cutrebra s/7/7. 'Dflcws o/eae, skin rope ( Derwfl/o/fl? /zom/w/s), Drosophila (Z)msO/?/n7a πρ·), toilet fly spp·), Gastrophius spp., HyZemyia s /ψ,), Hyjppobosca spp., Hypoderma spp., genus -18- 200812490 {Liriomyza spp.), green, exhausted JjAicilia spp), Musca spp· ), green 蝽 (A^zarfl spp·), nose rope, Swedish straw rope (C^cz>?e//fl/rzY), beet leafs, spring wheat (species) ropes CPkrMa πρ·), 螫 rope feathers f?·), 牛it (Tabanus spp·), Tannia spp·, Tipula paludosa, filthy rope M [Wohlfahrtia spp).

10 15

Gastropoda organisms, for example, Ariana (4γζ·ο« s/τρ·), Bumblebee spp·), vesicular spp·), larvae (Derocerfl^ spp.), genus Gfl沁a spp·), vertebral snail (as in spp·), snail ((9«come/ama spp·), snail snail (Swcckea spp.) Helminths, for example, duodenum Hookworm {Ancylostoma duodenale), Ceylon hookworm (ceylanicum), Brazilian hookworm XAcylostoma braziliensis), Ancylostoma spp., Ascaris lubricoides, line genus, and Bradgzb ma/ Βζζ·), Brwgk timori, Bunostomum spp·, ^XChabertia spp·), branch C (C7o/7〇rc/zz\y羽7·), Cooper-like nematode Genus (CoopeWa feather σ·), Gram-like liver fluke (9), filamentous lung worm (Dz'ci less ocflw/ws filaria), worm XDiphyUobothrium latum), nematode XDracuncuhis 仏), 绦嘉(五c/nTiococcws, Echinococcus multilocularis, Enterobius vermicularis, Faciola spp, Haemonchus spp, t Intestine A ( Heterakis spp·), short,], ligated film %螽 (Hymenolepis like m<a), //yoWrongw/i^wp·, LoaZoa, 12 fingers-19-20 200812490 Intestine Nematodes are t7·), Neesophagostomum spp., XOpisthorchis spp·), Iris worm (<9wc/zocerciz vo/vw/like), Bovine filaria spp ,), Schistosmen spp, 5 Strongyloides fuellebomi, Caenorhabditis elegans «like Wi/es stercoralis, Stronyloides spp·, XTaenia saginata, hook strip: KTaenia solium ), Trichinella spiralis (Xtrichinella spiralis), p native hairy nematode (7>/c/n>?e//fl wai/va), Trichine Ha britovi, Trichinella nelsoni, spur A 10 {Trichinella pseudopsiralis), Trichostrongulus spp., Trichuris trichuria, XWuchereria bancroftf). It is also possible to control protozoa, for example, Eimeria.

Heteroptera organisms, for example, melon worms (4 like tristis, Antestiopsis spp., Blissus spp, calocoris i5 spp, Campylomma livida, Cavelierus spp· , Beauty A (C/mex India;?), Peanut Yellow Blinde (CreowHai/es/Add), Pepper Margin _ {Dasynus piperis), Dichelops furcatus, Diconocoris hewetti, Meishen Gong Tao (Dysdercus spp· ), Euschistus spp., Eurygaster spp., Heliopeltis spp., Horcias nobilellus, Leptocorisa spp., Leptoglossus phyllopus, genus (Aygws Feather 9·), Cane black long 蝽 (Macropa excflva / (10)), 蝽 蝽, 蝽 · 蝽 蝽 ) ) ) 稻 稻 稻 稻 稻 ) ) ) ) ) ) ) ) ) ) ) ) ) ) ) ) ) ) ) ) ) ) ) ) ) ) ) ) ) ) ) ) ) )蝽(P/ezoi/orws, cotton pseudo-spotted leg 蝽ser/aiws), -20 - 200812490

Pseudacysta persea, Rhodnius spp., Sahlbergella singularis, rice black, sea {Scotinophora spp, net, {Stephcmitis nashi), Tibraca spp., Triatoma spp. Homoptera organisms, for example, the genus Hymenoptera (jqyr recognizes os/pon 5 spp·, Aeneolamia spp., Agonoscena spp,, Aleurodes SPP·, family, whitefly (Aleurol〇bus barodensis) ), Aleurothrixus spp., Amrasca spp., Anuraphis cardui, AonidieHa _ 577;?·' 'Pear worm teeth (for pzW), apple worms spp·), grape rafters (Arboridia) Apicalis), Aspidiella spp., Aspidiotus spp., Atanus spp., Aulacorthum solani ^ ^ ^ {Bemisia spp.) > ^ (Brachycaudus /ze//c^rj ^7), microtubule 蚜明9·), vegetable [blown powder] worm teeth (Brevicoryne, small rice brown planthopper (Ca//zg less ροπα marginata) ^ Carneocephala fulgida, cane cotton 15 (Ceraiovflcimi / /cm /gerfl), Cercopidae, Turtles {Ceroplastes spp), Wan Wan: I Management Field { Chaetosiphon fragaefolii), bb, Dong Xue M Yu (Chionaspis tegalensis), 缉 (Chlorita onukii), 蜗桃票, Chromaphis juglandicola, Chrysomphalus ficus, 蝉 (C/cflt /w/ina mbila), 20 Coccomytilus halli, Coccus spp·, Cryptomyzus rfbis, Dalbulus spp·, Dialeurodes spp, (Diaphorina spp.), Diaspis spp. Drosicha spp., Dysaphis spp., Dysmicoccus spp., 蝉叶蝉 (five m/70 (XSCfl 5/7/7·), apple (mian) fangs (five) , 斑叶蝉-21 - 200812490 {Erythroneura spp·,, leaf 蝉 (five like bihbatus), root fen (Geococcws, glazed leaf 蝉 (//oma/oc/bca, peach

10 15 ^M^^(Hycdopten4sarundinis),_^(Iceryaspp·),··{Idiocerus spp.) , Idioscopus spp. J ^ M ^ (Laodelphax striatellus), post *[Lecanium spp·), proficiency (Lepidosaphes spp ·), 齐莱场 [Lipaphis erysimi)^^^^^[Macrosiphumspp·)' Mahanarva fimbriolata, high % Makisaki {Melanaphis sacchari), Metcalfiella spp•, 暮 各 各 (Metopolophium dirhodum), 禀, 遂平遂Monellia costalis, Monelliopsispecanis, Myzus spp., {Nasonovia ribisnigri, black, caudal release (Nephotettix print/?·), rice brown frisbee lugens), Oncometopia spp· , Orthezia praelonga, Parabemisia myricae ^ yjv ^ (Paratrioza spp.) 9 M ^ (Par/aior/a πρ·), wormworm teeth (corpse emp/z/gws s/7 /7·), Peregrinus maidis, life test (JPhenacoccus spp.), Phloeomyzus passerirdi, Phenodon humuli, Phylodon humuli, Phyloxera spp, I, Pinnaspis Aspidistra^), JPlanococcus spp, Protopulvinaria pyri Formis), Pseudaulacaspis pentagona, Pseudococcus spp., first (JPsyna spp., Pteromalus spp., Pyrilla spp., Fengling {Quadraspidiotus spp·), Quesada Gigas, Rastrococcus spp., Rhopalosiphum spp., oil black ash (for this "·"spp.), "如如,麦二岔财 gram/·/??) , West Indian fine round shield 蛉-22- 20 200812490 articulatus), rice crack (Sogata spp), white backed fly / wrcz / ena), flying years old (Sogflioi / es, horned owl (Si / cocep / za / a festina ), Tenalaphara malayensis, Tinocallis caryaefoliae, Tomaspis spp, Toxoptera spp, Trialeurodes vaporariorum, Trioza SPP·, leafhopper (Typhlocyba spp.), Unaspis spp., grape root nodules (F/Yews v/"yb//z·).

10 15 Hymenoptera organisms, for example, striata φφΓ/οπ SPP·), Hop 丨 ampampa spp., Lasius spp., Monomorium pharaonis , Great Huhai (Vespa spp·, . Isopoda creature, for example, rat vulgare) 'Oniscus aselius, Porcellio scaber, Isoptera, for example, Net termites spp·,, Taiwanese {Odontotermes sppj. Lepidoptera organisms, for example, white caterpillars (jcrom*Cia Wfl/or), electric worms/ewcome/iw), noctuidae, larvae arg//acea), soy moth (jnhcczr幻·α 印Ρ·), cabbage genus (price? factory buckle, cotton leaf perforated moth (Bucculatrix thurberiella), pine ^ J ^ (Bupaluspiniarius), leaf moth (Caeoec ^ flpWa ·), leaf moth (Capwa rei / cw / Cmfl), Carpocapsapomonella, Cheimatobia brumata, Chilo sp/7·', CTzoAionewna/wim/erima, Clysia ambiguella, longitudinally stable leaf moth ( Cnaphalocerus spp), May-23 20 200812490 Earias insulana, Ephestia kuehnie Ua, brown tail moth (five wproc, cut rootworm (Ewxoa πρ·), brown leafhopper

Mt[Feltia spp), MiGalleria mellonella, Helicoverpa spp., Heliothis spp., Hofmannophila 5 pseudospretella, magnanima,

Hyponomeuta padella, Lapkygma spp., Lithocolletis blancardella, Lithophane • antennata, Loxagrotis albicosta, dance [Lymantria spp·,, Canopy caterpillar (Ma/flfc (10) oma new pair r/a), Brassica chinensis (Mame vs. rfl 10 heart-like? Sinking), larvae reenvironment re/7 recommended t/a), armyworm (M sound and 'nocturnal moth!?·), rice Negative mud worm (Ow/ewa or less zae), pine worm (corpse (10) o / b / 7 (wewe), (cotton) red mold mites (Pec " T7 〇 /? / zom, orange fine moth « 仏Along C/ire//a), Pieris spp., Plutella xylostella, XProdenia i5 spp., Pseudaletia spp., 3l aerobic (Pseudoplusia _ zVzc) /wt/elike) 'Wild model (Pyraz^ifl ·Ζ>ζ·/α/ζΧ), (Bug worm) SPP·), Thermesia gemmatalis, Tinea pellionella, Ida bisselliella , QTortrix viridana), woven {Trichoplusia spp). 20 Orthoptera creatures, for example, jc/zeia domesticus' Blatta orientals, BlattUa germanica, GryHotaipa spp. L(Leucophaea maderae) 'Paper made {Locusta spp), _i^{Melanoplus spp), Pazhou University (Per/p/imeM dmeWcima), wasteland 蚱猛 (Sc/z/Wocerca -24 - 200812490 gregflWa) 〇 Siphonaptera creature, for example, Cerciiophynus spp 'Xenopsynci cheopis' 〇 5

10

Symphyla creatures such as 'the garden of the genus immaculate^) Thysanoptera, for example, the rice locust (%/(6) biformis) 'Enneothrips flavens 'the sacred horse (jprankliniella SPP·)' H horse (Heliothrips spp·) 'Hercinothrips femoralis, 'Kakothrips spp,, version of shovel \ horse, R}iipiphorothrips cruentatus, sacred horse {Scirtothrips spp), horse {Taeniothrips cardamoni), horse ( Thrips spp·) o Thysanura creatures, for example, scorpion saccharina. Plant parasitic nematodes include, for example, A. elegans spp.), Aphelenchoides spp., Belortoaimus spp., Bursaphelenchus spp., 1 Ditylenchus dipsaci, raising gold HJ% (Globodera spp.), Heliocotylenchus sigh 7?, Nematodes (Heteroderas/7/7.), Needleworm (Zowg/i/orwHpp.), Rootworm Nematode (Mebidogyne spp.), Root rot line (Pratylenchus SPP·), Radopholus similes, Rotylenchus spp., Trichodorus spp., Dwarf nematode XTylenchorhynchus spp·) XTylenchulus spp.), XTylenchulus semipenetrans, M. Xiphinema spp. ° -25-20. 200812490 Applying the active compound combination of the invention at certain concentrations or improving plant killing agents, safeners, growth Regulators may be used in, for example, anti-caries, fungicides, viricides, or agents, or as agents against MLOs that are resistant to viroids (νι_) = sputum; appropriate ' They are also two = things or then the drive's should be smothered into other Compound. Understand that the plant and plant parts that can be used to treat whole plants can be used to refer to all plant and plant groups, for example, the desired and unwanted wild plants or crop plants are optimal. Method or by biotechnology and genetic engineering === 15 square = aberdeen, including plants that transfer genes and those that are protected by plant-grown and unprotected plant varieties; plant parts can be Refers to all plants and organs on the surface of the plant and in the underground part, for example, shoots, leaves, flowers and roots, examples of which may be leaves, e-rods, tree stems, flowers, fruit bodies, fruits, seeds, Roots, bulbs, and (four) stems 1 Plant parts also include harvested materials and growing parts and materials, such as seedlings, bulbs, stolons, cuttings, and seeds. "Treatment of plants and plant parts with active compound compositions according to the invention, directly treating the plants themselves or acting on their surroundings, in the opposite, living spaces or storage, for example by dipping, sprinkling, evapotranspiration, in a conventional manner Atomization 'distraction, application, injection, and, for propagation material, especially seeds, can be treated by applying one or more layers of coating. -26- 20 200812490 The active compound combination according to the invention is particularly: The object is: r:: The present invention is considered to be more than (4) 'Most of the crop plants caused by pests, the oysters can appear early in the seed storage period and in the soil, and after the germination of the plant, a very short time _ The key point in the attack period is that the roots and seedlings of the growing plants are particularly sensitive, and even a small amount of damage can lead to the death of the whole plant, by using the appropriate composition to The germinated plants are therefore of particular interest. 15 20 The method of treating plant seeds to control pests has been known for a long period of time and is a goal of constant improvement. However, the seed often encounters a series of problems that cannot be satisfactorily solved, so it is necessary to develop methods for protecting the seeds and the plants in the germination so that the crops need not be applied immediately after sowing or after the plants are germinated. Protecting agents, in addition, = = to optimize the amount of active compound applied to provide the most appropriate protection against the seeds and plants in the bud, from attack by pests, but without the active compounds used Injury to the plant itself; in particular, the method of treating the seed should also take into account the insecticidal properties of the internal plant of the transgenic plant, so that the seed and the germinated plant can use the minimum amount of crop protection agent to achieve the most appropriate The present invention is also related, in particular, to a method for protecting a seed and a germinated plant against attack by a pest, comprising: treating the seed according to the combination of the active compounds of the invention; for protecting the seed according to the invention And methods of attacking plants in response to pests include a -27- 200812490 200812490 5

10 15 Method 'The active compound of one of the seeds and the type of the formula> and one! Up to 20 types of insect growth regulator treatment; the invention also includes a method wherein the seed is time, the active compound of the [type] and the species 1 to 2G extract & growth regulator treatment; the invention also relates The invention relates to the treatment of fresh-scented seeds and the plants germinated therefrom according to the present invention, and furthermore, the invention is protected against pests by treatment with the active compound combination according to the invention. Invasive seed; the present invention also relates to a seed which is treated simultaneously with an active compound of the formula and a species of 1 to 20 quinone growth regulator. The present invention also relates to the activity of hydrazine at different points. a compound and a seed of 1 to 2G_U line-touching; a composition according to the invention when the seed is treated with an active compound of the formula I and a seed to a 2() difficult insect growth regulator at different time points The active compound of (d) of the towel may be present on different layers of the seed, wherein the layers comprising a compound of formula I and a class 1 to 20 insect growth regulator may alternatively be separated by an intermediate layer; and also In the latter seed, the active compound of the formula I and to a class i to 2〇 ^ green insect regulators, based on the seed applied to the components in the coating manner thereof, or another layer or as a multilayer. One of the advantages of the present invention is that the particular systemic nature of the combination of compounds according to the invention means that the seed is treated in combination with these active compounds, 'not only protects the seed itself, but also protects the germinating plant from harmful Biological attack, in this way, eliminates the need for immediate treatment at the time of crop planting and shortly thereafter. -28 - 20 200812490 Another advantage is that the insecticidal activity of the individual active compounds is reduced according to the synergistic increase of the active compound combination of the invention. The activity of the two active compounds to be applied and, in addition, the insecticidal activity of the active compound composition according to the invention is much higher than that of the individual active compounds. It is expected that the activity of the two active compounds to be applied separately will make it possible to optimize the amount of active compound applied.

10 15

Similarly, the combination of activated persons according to the present invention can also be applied to the 'specially the seeds of the transgenic genes, from this; the growing plants are tested - the eggs are directly against the pests from f , ^ The active compound composition of the present invention treats such seeds, and the pest can be controlled by the second example of the insecticidal protein, and additionally protected by the active compound combination according to the present invention against According to the present invention, the active compound combination, as described above, is suitable for the protection of any of the plants, varieties of seeds used in agriculture, greenhouses, forestry or horticulture, in particular seeds used in plants: corn, peanuts =1'芸薹: I Ping, Soybean 'cotton' beet (such as sugar beet two meters, Shangliang and millet, wheat, barley, oats, rye, alfalfa, tobacco, horse yam or vegetables (such as tomatoes) The combination of the active compounds of the core is also dependent on the supply: j = the seed, it is important to use the seeds in the treatment of corn, A beans, 4 wheat, and rape or alfalfa. This issue (IV) Active Compound Combination -29· 200812490 The seed of the transgenic gene is also particularly important. It is customary that the type of plant seed to be treated contains at least one polypeptide which can control, in particular, insecticidal properties. Genes that are heterologous in expression, in this context, heterologous genes in the seeds of the transgenic genes may be derived from microorganisms, for example, BaciHus, Rkizobium, pseudomonas, and sand. R. serrata ^S^m^a), Trichoderma (IWc/zoi/erwa), Corynebacterium (C7imMc仏r), cystic endophytic bacteria (G/cw-like) or P. sphaeroides | The invention is therefore particularly suitable for the treatment of a gene which already comprises at least one heterologous source from the genus Bacillus, and which is present in a seed which is active against the transgenic genes of 0 European corn borer and/or corn cutworm, particularly preferably The heterologous gene is derived from S. cerevisiae (eg, (7/milk) in the context of the present invention, the active compound combination according to the invention is applied to the seed either alone or in a suitable formulation, preferably Ground, the seed is enough to avoid It is treated in a steady state where it is damaged during the treatment; 15 Usually 'seeds can be treated at any point between harvesting and sowing. Seeds are usually isolated from plants and have removed cobs, shells, stems, Jackets (laughs), hairs or flesh. When handling seeds, it is usually very important to include the amount of active compound combination according to the invention applied to the seed and/or the amount of additional 20 added to the seed. It is considered that the germination of the plant is not adversely affected or causes damage to the plant, in particular, the active compound which can cause phytotoxicity at a certain application rate. The active compound composition can be converted into Conventional formulations, for example, solutions, emulsions, wettable powders, water- and oil-based suspensions, powders, • 30-200812490 dusts, pastes, soluble powders, soluble granules, suspension-emulsion concentrates Microcapsules infiltrated with active compound, active substance, fertilizer, and coated with ## were used. The long-term production of these ingredients is produced in a known manner, for example,

The substance is mixed with a stretching agent, and the stretching agent refers to a liquid solvent and/or a material of the type I is selectively selected as the surface type _, 卩卩, emulsifier class or eight =

10 15

Classes and/or foam formers; formulations may be formulated as appropriate;;: formulated before use or at the time of use. (d) clothing or preparations suitable for use as a user (4) in addition to the living itself and / or its derived formulations (for example, spray liquid, seed coating liquid is, for example, water, polar and non-polar Organic Chemistry ★ Nightlife, for example, aromatic and non-aromatic hydrocarbons (eg, hydrocarbons, sulfhydryls, steroids, alkylnaphthalenes, chlorobenzenes), alcohols and polyols (appropriate , = = substituted, etherified and / or esterified), ketones (for example, acetone, cyclohexyl), painted scorpions (including fats and oils) and (poly) ethers, unsubstituted And smear, 酼 姑 ' ' ' ' ' ' ' ' ' ' ' ' ' ' ' ' ' ' ' ' ' ' ' ' ' ' ' ' ' ' ' ' ' ' ' ' ' ' ' ' ' ' ' ' ' ' ' ' ' ' ' ' ' ' ' ' ' ' ' ' ' ' ' ' ' ' ' ' ' ' ' ' ' ' ' ' ' ' ' ' ' ' ' ' ' ' ”, 、,六添 If the extender used is water, it is also possible to use, for example, organic=agents as auxiliary solvents. Mainly, suitable liquid solvents are: aryl^', for example, bismuth benzene, hydrazine Benzene or alkylnaphthalenes; chlorinated aromatics $ gasified lunar aliphatic hydrocarbons, for example, chlorobenzenes, ethylene ethides or bismuth sulphate. f and / or special biological properties, suitable adjuvants for blood type are: extenders, solvents and carriers. -31 - v v200812490 aliphatic hydrocarbons, such as cyclohexane or paraffin, for example, petroleum Partitions; minerals and vegetable oils; alcohols, for example, butanol or glycol and their ethers and esters, ketones, for example, acetone, methyl ethyl ketone, methyl isobutyl ketone or cyclohexanone Strong polar solvents such as diterpenoids; and water. Suitable solid carriers are: for example, ammonium salts and ground natural minerals such as kaolin, clay, talc, chalk, quartz, USA Activated clay, montmorillonite or diatomaceous earth, and finely divided synthetic minerals, for example, highly dispersed cerium oxide, alumina and cerium salts; solid carriers suitable for the preparation of granules, for example, milling Broken and divided natural rocks, such as calcite, marble, pumice, sepiolite and dolomite, and synthetic particles of inorganic and organic materials, and particles of organic materials, such as paper, sawdust, coconut Shell, corn cob and grass disaster Suitable emulsifiers and/or foam formers are, for example, nonionic and anionic emulsifiers, for example, polyoxyethylene fatty acid esters, polyoxyethylene aliphatic alcohol ethers, for example, alkyl aryl polyglycol ethers Classes, alkyl sulfonates, alkyl sulfates, aryl sulfonates, and protein hydrolysates; suitable dispersing agents are nonionic and/or ionic materials, for example, the following alcohol-POE- and / Or -pop-ethers, acid and / or p〇pp〇E esters, alkyl aryl and / or POP-POE ethers, fat _ and / or p〇p_p 〇 E adduct, p 〇 E _ and / or POP-polyhydroxy derivatives, p〇E_&/ or p〇p_sorbitol or-sugar adducts 'alkyl or aryl sulfates, · alkyl- or aryl sulfonates and An alkyl or aryl disc salt or an associated p-ether adduct, in addition, suitable oligo- or polymers, for example those derived from vinyl monomers, from acrylics, from EO and / or? The ruthenium itself or in combination, for example, (poly)alcohol-32-200812490 or (poly)amines; it is also possible to use lignin and its sulfonic acid derivatives, unmodified and modified cellulose, aromatic and / Or an aliphatic sulfonic acid and its adduct with methadone. Adhesives, for example, carboxymethyl cellulose and natural and synthetic polymers in the form of powder, granules or milk 5, such as gum arabic, polyvinyl alcohol and polyvinyl acetate, and natural Phospholipids, for example, cephalin and lecithin, as well as synthetic phospholipids, can be used in the formulation. It is also possible to use coloring agents such as inorganic pigments such as iron oxide, titanium dioxide and Prussian blue, and organic dyes such as quinone dyes, azo dyes and metal phthalocyanine dyes, and micronutrients. Ingredients such as iron, sulphur, copper, diamond, molybdenum and zinc. Other possible additives are perfumes, mineral or vegetable oils, optionally modified oils, paraffins and nutrients (including micronutrients) such as salts of iron, lanthanum, boron, copper, diamond, indium and zinc. 15 Stabilizers, for example, cryogenic stabilizers, preservatives, antioxidants, light stabilizers or other agents used to improve chemical and/or physical properties, may also be present in formulating agents. in. The formulation typically comprises between 0.01 and 98% by weight of active compound, preferably between 0.5 and 90%. 20 according to the active compound combination of the present invention, in the form of a commercially available formulation, or from the formulation to a use form, can be combined with other active compounds (eg, insecticides, attractants, infertility agents, sterilization) Agents, acaricides, nematicides, fungicides, growth regulators or herbicides) are used as a mixture, and the insecticides include, for example, phosphates, amino-33-200812490 formates, Carboxylic acid esters, chlorinated hydrocarbons, phenyl ureas, substances produced by microorganisms, and the like. It may also be used in combination with other known active compounds (e.g., herbicides) or with fertilizers and growth regulators. Active compound group according to the invention when used as an insecticide

10 15

The combination may also be used in the form of a commercially available formulation, or from the formulation to a use form in which the mixture is used in combination with a synergistic agent. The synergistic agent is one which enhances the action of the active compound but is not necessarily active per se. Substance. The active compound in the use form formulated from the commercially available formulations may vary widely. The active compound concentration in the use form may range from 0.00000001 to 95% by weight of active compound, preferably 2 It is between 0.00001 and 1% by weight. The manner of application is in a manner suitable for the type of use. As already mentioned above, all plants and their parts can be treated according to the invention, in a preferred embodiment, for the treatment of wild plants, plant cultivars ' or those obtained by conventional biological breeding methods. , for example, those obtained by hybridization or protoplast fusion, and their various parts: a better specific implementation, the duck is genetically engineered by the genetic engineering f1 and obtained by traditional methods, transformed organisms, And its various parts; the so-called "parts of the upper body," or "plant parts," whose meaning is as explained above. Also, the plant for treatment according to the present invention is such that it can be obtained by conventional breeding, by mutation and by recombinant DNA technology, having a novel property ("feature") of 20 200812490, which can be cultivated. Variants (cultivars), homotypes (biotypes) or genotypes (gen〇types). 5

10 15 depending on the plant variety or plant cultivar, its distribution and growth conditions (soil, climate, growth period, nutritional status), the treatment according to the invention may also lead to superadditive ("co-multiplying" effects, thus, For example, reduced application rates and/or augmented activity profiles and/or increased activity of materials and compositions that can be used in accordance with the present invention, preferred plant growth, greater resistance to high or low temperatures, and even drought or Rich or resistant to soil salinity, increased flowering period, easier harvesting, accelerated maturity, higher yield, better quality and/or higher nutritional value, better harvested products The storage stability and/or processability may exceed the actual expected effect. Plants or plant cultivars of preferred transgenic genes to be treated according to the present invention (ie those obtained by genetic engineering methods) Including all those, genetically engineered, to obtain beneficial and useful features of the genetic material of the species' examples of such characteristics are: better plant growth, more resistant to high temperatures or loud, warmer 'more resistant Drought or salt content in water or soil, increased flowering period, easy castration, accelerated ripening, higher yield, better harvest and/or higher nutritional value, better storage of harvested products Stability, workability, and examples of such characteristics that deserve special emphasis are: = and other pests (such as 'insects, genus, plant pathogenic: straight and: ΐ and / or viruses) with better defense Sexuality also increases the plant's miscellaneous compound. The plant that can be mentioned as a transgenic gene is an important crop plant, such as grain (wheat, rice, rice, and, 'beet', beans, and other vegetables. Variety, large; grass horse -35-20 200812490 by vegetables and fruit trees (apple, pear, citrus and vine), and especially to emphasize corn, soybean, horse yam, cotton and rape, especially The emphasis is on the ability to increase plant resistance by the formation of toxins in plants to the ability of 4 & worms, worms, nematodes and oxen and ticks, especially those borrowing 5 from the bacterium (Parts such as / / / group wr / «g7 · (9) life) base Due to materials (eg 'by the genes CrylA (a), CrylA (b), CrylA (c), CryllA, CrylllA 'CryIIIB2, Cry9c, Cry2Ab, Cry3Bb and CrylF _ and also including its composition) "Bt plants,,"; other features that are particularly emphasized are: systemic resistance (8-8), SyStemin, Phytoalexins, elicitors, and resistance genes. Related performance of proteins and toxins to increase the plant's defense against fungi, bacteria and viruses; it is also particularly emphasized that plants have certain herbicidal compounds (eg, imidazolinones, sulfonamides) Increased tolerance of the base ureas, glyphosate or phosphinotricin (eg "PAT" based 15); genes involved in the desired characteristics are undoubtedly also associated with other genes The mixed form appears in the plant of the transgenic gene, and the example of the "Bt plant" which can be mentioned by B is a corn variety, a cotton variety, a soybean variety, and a horse potato sold under the trade name described below. Variety: YIELD GARD® ( For example, corn, cotton, soybeans, KnockOut8 (such as corn), StarLink8 (such as corn), Bollgard8 (cotton), Nucotn8 (cotton) and NewLeaf® (maize), can be mentioned as resistant to herbicides. The plant species are corn, cotton and soybean varieties, which are sold under the trade names Roundup Ready8 (corner, such as corn, cotton, soybean), Liberty Link8 (for phosphinotrix, such as canola) , IMI® (Taste-36-200812490 Oxazolidinone) and STS8 (sulfonyl urea-resistant, such as corn); herbicide-tolerant plants (herbicide-tolerant plants bred in a conventional manner) Vendors (such as corn) under the name Clearfielf®, of course, also apply to plant cultivars that have these genetic characteristics or that will be developed and/or sold in the future with 5 genetic features to be developed. The plants listed can be treated according to the invention in a particularly advantageous manner using the active compound combinations according to the invention, which are also suitable for the treatment of these plants, in particular in the preferred range of active compositions. It is emphasized that the plants are planted at the combination of active compounds specifically mentioned in the present text. The active compound combination according to the invention, which is not active against pests in plants, hygiene and storage products, can also combat animal parasites (external-parasites and endo-parasites) in the field of veterinary medicine, such as hard Wall winds, soft niches, beasts, leafhoppers, flies (fly and fly), parasitic fly larvae, 15 scorpions, head lice, feathers and fleas, these parasites (worms) include: Anoplurida ) organisms, for example, Haematopinus _ spp., Linognathus spp., Pediculus spp., Phtirus spp., buffalo Solenopotes spp.). Mallophagida and Amblycerina and Ischnocerina 2, including, for example, Tdmenopon spp., Menopon spp., Trinoton spp., Bovicola spp., Werneckiella spp. Lepikentron spp., Damalina spp., Trichodectes spp., Felicolaspp. Diptera and Nematocerina and Brachycerina organisms, for example, Aedes spp., Anopheles spp., Culex pipiens Genus spp., Simulium spp., Eusimulium spp., Phlebotomus spp., Lutzomyia spp., Culicoides spp. , genus of the genus (Chrysops spp.), Hybomitra spp., Atylotus spp., Tabanus spp., Haematopota spp., Philipomyia spp. Beetle (Braula spp.), Musca spp., _Hydrotaea spp., Stomoxys spp, Haematobia spp., Morellia spp. ), the toilet genus (Fannia 10 spp·), the genus Glossina spp., the genus Calliphora spp., the green rope (Lucilia spp.), the genus Chrysomyia spp. Genus (Wohlfahrtia spp.), Sarcophaga spp., Oestrus spp., Hypoderma spp., Gasterophil Us spp·), Hippobosca spp., Lipoptena spp., Melophagus spp., Siphonapterida, for example, Pulex spp., 栉 栉 蚤Ctenocephalides spp., Xenopsylla spp., Ceratophyllus spp. Heteropterida organisms, for example, bed bugs (Cimex spp.), 2 TriTriatoma spp., Rhodnius spp., Panstrongylus spp. (Blattarida) creatures, for example, Oriental 蜚蠊 (万^如仏), American cockroach, Blattella germam'ca, Supella spp. -38 - .200812490

10 Acari (Acarina) and post-thoracic and meta- and Mesostigmata organisms, for example, Argas spp., Omithodoros spp. ), Otobius spp., Ixodes spp., Amblyomma spp., Boophilus spp., Dermacentor spp. Haemophysalis spp., Hyalomma spp., Rhipicephalus spp., Dermanyssus spp., Raillietia spp., Pneumonyssus spp ·), Sternostoma spp., Varroa spp. Actinedida (also known as Prostigmata) and Aphidida [Acaridida, also known as no valve Astigmata] organisms, for example, Acarapis spp., Cheyletiella spp., Ornithocheyletia spp., Myobia spp., Psorergates spp. Demodex spp., Trimculcula spp., Listrophoms spp·, Acams s Pp·), Tyrophagus spp., Caloglyphus spp., Hypodectes spp., Pterolichus spp., Psoroptes spp., Chorioptes spp·, ear Otodectes spp., Sarcoptes spp., genus genus (1^(^(^(^8 5卩卩.), Knemidocoptesspp·), genus Cytoditesspp.), Laminosioptes spp. The active compound composition according to the invention is also suitable for use in productive animals that control arthropods to avoid harassment of agriculture, such as cattle, sheep, goats, horses, Pig, scorpion, Lu Cong, buffalo, rabbit, chicken, turkey, duck-39- 20 200812490 Child, goose and bee, other pets, such as dogs, chow, birds and fish, and so-called experimental animals' , money, scorpion gas, big old = with small mice; by controlling these arthropods, can reduce feed: mortality and production (meat, milk, wool, fur, eggs, honey, etc.) 5 纟 use according to this The combination of active compounds of the invention can reach a greater economy: The animal feed. 1 The compounds according to the invention are used in the field of veterinary medicine and in animals. They are administered by internal means in a known manner, such as, for example, a key, a capsule, a drink, a granule, a paste, a bolus. By means of non-digestive administration, for example, injection (intramuscular, subcutaneous, intravenous, intraperitoneal, etc.), via implantation, transnasal administration, via Skin application 'eg m bath, spray m, pour and spot, rinse, sprinkle powder, and with molded articles containing active compounds, such as collars, ears 5, tail rings, limb bandages, reins, Identification device, and so on. 15 μ in bovine, poultry, (iv), etc., active compound combination • may be used as a formulation (eg powder, emulsion, flowable composition) containing the active compound in an amount of from ii 80 〇 / 〇 weight For use, directly or after dilution of 100 to 10,000 times, or as a chemical bath. Furthermore, it has been found that the active compound combination according to the present invention has a strong action of a tailworm for combating insects which destroy industrial materials. The following insects are exemplified and preferred examples, but are not limited to this: A ** class 'for example, 'Tianniu Niu (gong r 叩 办 “ 力 力 力 , , , , , , , , 〇 〇 〇 〇 天 天 天 天 天 天 天 天 天 天j 轰(Anobium punctatum), red hair thief t (Xestobium 200812490 5

10 15

Rufovillosum), Ptilinus pecticornis, Dendrobium pertinex, Ernobius mollis, Priobium carpini, brown stupid (Lyctus, African stupid, Zyci (10) planicollis, Lyctus pubescens, Trogoxylon aequale , Minthes rugicollis, small genus (Xyieborus spec,, Tryptodendron spec, coffee, non-black scorpion, Bostrychus, brown scorpion, brunneus, sinoxylon spec), 咕l亀{Dinoderus minuteus) Hymenopterans, for example, JWvewcMS) 'C/rocerws gigOs taignus, Urocerus augur \ white sacrifice class' such as 'European wood white sacrifice (magic 3 / (^ factory so /? Heart / (: 〇 / / to), Australian white 蠛 (Cr) erma 6revb), desert termites (/fe such as wema indicola) 'Running loose white weave, Reticulitermes flavipes), Reticulitermes santonensis, South view 氙 white binding ^Reticuiitermes /wczykgT^) 'Masioier/wes (Zootermopsis nevadensis) Taiwanese termite formosanus; Western-style fish 'for example' Western Fish (Z coffee is referred to herein as industrial material, understandable refers to inanimate materials, such as 'preferably refers to plastics, detergents, pastes, paper and cardboard, leather, wood And processed wood products and coating compositions. Ready-to-use compositions, if appropriate, may further comprise additional insecticides -41 - 20 200812490 and, suitably, one or more other fungicides. For the additional additives, reference may be made to the above-mentioned insecticides and fungicides. The active compound combinations according to the invention can likewise be applied to objects which are in contact with seawater or salty water. In particular, the hull, the screen, the net, the building, the mooring and the signalling system are used to counteract the contamination of the attachments. Furthermore, the combination of active compounds according to the invention, alone or in combination with other active compounds, may Used as an anti-bioadhesive agent. This active compound combination is also suitable for the control of animal pests in the protection of domestic, sanitary and storage-products, especially in enclosed spaces. Insects, spiders and worms (for example, in residences, workshops, offices, garages, etc.), in order to control these harmful animals, they can be used alone or in combination with other active compounds and adjuvants for the family. Within the insecticidal products used in the home, they are active against sensitive and resistant varieties and all their developmental stages, including: Scorpionidea organisms, for example. Acarina creatures, for example, Persian concealed to resemble 20 pea/cws), drgas, Brassica sinensis Mp·), chicken skin thorns (Dermanyssus, home sweetness ίί/owe pair / cws), blunt Edge worm (OmY/zot/orws wowZmi), jk Rhipicephalus sanguineus, Trombula alfreddugesi, Neutrombicula autumnalis, Dermatophagoides -42- 200812490 pteronissimus, Dermatophagoides forinae 〇 spiders (Araneae ) biology, for example, Aviculariidae, Araneidae; 5

10

Obilines creatures, for example, chelifer), Pseudoscorpiones cheiridium, 1 edge [Opiliones phalangium). Isopoda creatures, for example, the ball mouse (the worm (10) asellus), black, tidal (Porcellio scaber), the genus Diplopoda, for example, zebra guttulatus ^ Polydesmus spp.; Chilopoda creatures, for example, eat fruit and drink spp·. Zygentoma, for example, CYewo/epbma spp., Lepisma saccharina, Lepismodes inquilinus (Blattaria), for example, Oriental 蜚蠊on·(9)Μ// α), German gerwamia), BiatteHa asahinaf, Leucophaea maderae, Panchlora spp·, Parcoblatta spp·, Periplaneta australasiae , American cockroach (Per / /? / (10) eia, brown big cockroach (10) efl), smoked cockroach (Periplaneta fuliginosa), long fH treatment (Supella longipalpa). Saltatoria creatures, such as 'family domesticus' ° -43 - 20 200812490 The genus Dermaptera, for example, the European ball python (For/fcw/a auricularia) ° Isoptera, For example, common dry wood termites (Kalotermes spp.), net termites (Reticulitermes spp.). Psocoptera organisms, for example, Lepinatus spp., Liposcelis spp.

10 15

Coleoptera organisms, for example, Anthrenus spp., Attagenus spp., Dermestes spp., Latheticus oryzae, genus Necrobia spp.), Ptinus spp., family thieves, Sitophilus granaries, Sitophilus oryzae, Sitophilus zeamais, and Stegobium paniceum. Diptera organisms, for example, Aedes aegypti, Aedes aegypti (defies albopictus), Aedes aegypti (jedes), Anopheles spp., Calliphora erythrocephala, Chrysozona Pluvialis, Culex quinquefasciatus, Culex pipiens, Cw/ex Mr, fruit rope (i>oso/7/n7a spp·), toilet rope canicularis, home rope ( Musca domestica), Phlebotomus spp·, cararia rope, black rope spp.), Stomoxys calcitrans, Tipula paludosa, Lepidoptera, for example, small grisella , Gloria mellonena, Plodia interpunctella, Moth (77-type a cloacella), Nete moth (TVwea -44-20. 200812490 pellionella), Tineola bisseniella. Siphonaptera creatures, for example, Ctenocephalides canis, KCtenocephalides felis), KKPulex irritans, KTunga penetrans, Oriental l HXenopsylla cheopis) o

10 15

Hymenoptera organisms, for example, Crowpowo s herculeanus, tickets, Lasius fuliginosus, ♦ Lasius niger ^ ^ ^ (Lasius umbratus) 5 M ^ (Monomorium Pharaonis), Paravespula spp., paving ant (Teirawor/ww caespitum). Anoplura organisms, for example, PeAcw/ws capitis, Pediculus humanus corporis, Pemphigus spp., Phylloera vastatrix, Phthiruspubis. Heteroptera ) Creatures, for example, bed bugs (C/wex hemipterus), odorous (Cimex lectularius), Rhodimis prolixus, blood-sucking prisoners (TWaiowfl / «/e pairs (ms). In the field of household insecticides, they are used alone Or in combination with other suitable active compounds, for example, in combination with phosphates, urethanes, pyrethroids, novels, growth regulators or other known insecticides. The following types are used: aerosols, non-pressurized sprays, such as pumped sprays and atomized sprays, automatic atomization systems, atomizers, foams, gels, with cellulose Or a vaporizer product of a vaporizer sheet made of a polymer, a liquid vapor, a gel and a thin film vaporized product, -45- 20 200812490 paddle-driven steamed product, no consumption _, a slit-type evaporation system, a moth, I am catching bags and catching moths , made into granules or dust, placed in a bait for spreading or used in a lure equipment station. [Embodiment] The good insecticidal and acaricidal activity of the active compound combination according to the invention is followed by The examples illustrate the fact that the individual active compounds exhibit a weak effect and the composition exhibits a much greater effect than the sum of the effects of the individual components. When the activity of the active compound combination always exceeds the sum of the activities of the individual active compounds To have a synergistic effect. The expected activity of a given composition containing two active compounds can be calculated according to the formula of SR· Colby (Weeds 15 (1967), 20-22) as follows: If X Represents the percent kill rate (%) of the untreated control group when the active compound A is applied at an application rate of m g/ha or at a concentration of si ppm, and γ represents the application rate at a g/ha or The percentage of kill rate (0/〇) of the untreated control group when active compound B was applied at a concentration of n ppm, and E represents the application rate at HL and IL g/ha or at concentrations of m and n ppm. Application activity -46- 200812490 x · γ then Ε = X + Υ - 100 If the true kill rate exceeds the calculated value, then the effect of the composition is superadditive, ie, a synergistic effect occurs, In this case, the true observed kill rate needs to exceed the expected kill rate (Ε) calculated using the above formula.

_ Example A Cotton Test Solvent: 7 parts by weight of dimethyl decylamine emulsifier: 2 parts by weight of alkyl aryl polyglycol ether 15 is a formulation which produces a suitable active compound, 1 part by weight of activity The compound is mixed with the amount of solvent and emulsifier, and the concentrate is diluted to the desired concentration with water containing an emulsifier. _ Incorporate the cotton leaf that has been seriously infected with cotton aphid (but the card is added) into the preparation of the active compound at the desired concentration. After the period of the desired period, the percentage of killing is determined, 1%% means that all the insects have been killed; 0% means that no field insects are killed, and the measured kill is killed. Rate into the Colby formula (see Form 1}. In this test, according to the application rate of the following active compound group 25 5 'phase whispered to the hemiplegic secret active compound, _ county increased activity 0 -47- .200812490 Table A, page 1 Insect Cotton Injury Tests Active Compound Concentration (DDm) Kill Rate after 1 Day (%) Compound (la) 0.16 20 Compound (lb) 40 80 0.16 15 Flufenoxuron 100 25 according to the invention: Compound (la) + fluorofenon (1: 625) 0.16 + 100 Measured value * 85 Calculated value ** 40 Lufenuron 100 0 According to the invention: Compound (Ib) + Lu Fenlon (1 · · 625) 〇 · 16 + 1 〇〇 measured value * 75 calculated value ** 15 methoxyfenozide 100 0 According to the invention: compound (la) + mefenfen (1: 625) Xvi 4-1^ Λ- ηα t L· 0.16 + 100 60~~ Calculated value ** 20 艨 The present invention: Compound (lb) + Immolol (1: 25) __1±100 Measured value of $95^^calculated value** m novaluron 100 --- 0 According to the invention: compound (lb) + novalon (1 : 25) _1 ± 100 98 80 measured value = actual measurement Activity ** calculated value = activity calculated using Colby's formula -48- 200812490 Table A, page 2 Insect plant cotton damage (p/ih test killing rate after 6 days of active compound concentration (% Compound (la) 0.16 75 Compound (lb) 0.8 0.16 60 10 Fenfenoxon 100 10 According to the invention: Compound (Ib) + Flufuron (1: 625) 0.16 + 100 Measured value 1 Calculated value 75 75 19 novaluron 100 0 According to the invention: Compound (Ia) + ruthenium (1: 625) 0.16 +100 Measured value 1 Calculated value 2 85 75 Triflumuron 200 0 According to the present Inventive: Compound (Ib) + Sanfulong (1: 250) 0.8 + 200 Measured value 1 Calculated value 2 75 60

-49- 1 measured value = actual measured activity 2 calculated value = activity calculated using Colby's formula 200812490

Example B Peach "(Mjzms /rerWcae) Test Solvent: 7 parts by weight of dimethyl carbamide emulsifier: 2 parts by weight of alkyl aryl polyglycol ether

10 15

To produce a suitable formulation of the active compound, 1 part by weight of the active compound is mixed with the amount of solvent and emulsifier, and the concentrate is diluted to the desired concentration with water containing the emulsifier. Cabbage leaves (7) o/^acea), which has been heavily infected with the green peach (Mj/ζ(10) perWcae), are infiltrated into a solution of the active compound of the desired concentration for treatment. The month of the month 'wo% died, will be determined after a period of time, the total number of killed mites have been killed; 0% means no 埼 *, the ratio of the kill rate of the knife into the Colby formula (See Form 1). The killing is increased and the activity is increased. For example, according to the application rate mixture, the synergistic person described below is administered individually, and (a) does not exhibit synergistic multiplication. • 50- 200812490 Table B, page 1 Insecticide-infested insects (MjzMspers/ciie) Test active compound concentration (ppm) Kill rate after 1 day Compound (la) 0.16 5 Compound (lb) 0.8 10 Lufenlong (liifenurcm) 100 0 According to the invention: Compound (Ia) + Luflon (1 ··625) ❹.16 +100 Measured value 1 Calculated value 2 65 5 According to the invention: Compound (Ib) + Lufenlong (1: 125) 0.8 + 100 Measured value 1 Calculated value μ 65 10 methoxyfenozide 100 0 According to the invention: Compound (la) + fenfenol (1: 625) ❹.16+ 100 Measured value 1 Calculated value 2 45 5 According to the invention: Compound (Ib) + fenfenol (1 ·· 125) 0·8+ 100 Measured value 1 Calculated value 2 25 10 Triflumuron 200 0 According to the invention Compound (la) + Sanfulong (1: 1250) 0.16 + 200 Measured value 1 Calculated value 2 20 5 -51 - 1 Measured value = Actual measured activity 2 Calculated value = Activity calculated using Colby's formula 200812490 B, page 2 Insects of Insects Peach Tests Active Compound Concentration (ppm) Kill Rate after 6 days ί%) Compound (la) 0.16 0 Compound (lb) 0.8 0 Flufenoxuron 100 10 according to the invention: compound (la) + fluorofenon (1: 625) 0-16 + 100 measured value * calculated value ** 45 10 according to the invention: compound (Ib) + fluorine Fenlon (1: 125) 0.8 +100 Measured value * Calculated value h 60 10 Triflumunm 200 0 According to the invention: Compound (Ib) + Sanfulong (1: 250) 0.8 + 200 Measured value* Calculated value ** 15 0 5 * Measured value = actual measured activity ** calculated value = activity calculated using Colby's formula - 52-

Claims (1)

200812490 X. Patent application scope: 1. An active compound composition comprising at least one compound of formula (I) 10 wherein R represents methyl or cyclopropyl, and at least one compound selected from the group consisting of: a) phenylhydrazinoureas, such as chlorfluazuron 15 2·二福隆(diflubenzuron) 3 · Lufenuron 4. Defulong (teflubenzuroii) -53- 20 200812490 5. 三福隆(triflumuron) 10 6. novaluron 15 8. Double bistrifluron 9. flufenoxiiron F -54- 20 200812490 5 1 Fluoroxuron 10 11· poly-urea (noviflumuron) 15 12. Buprofezin? H3 b) chitin synthesis inhibitors, such as 13 · cyromazine -55- 20 200812490 C) Infant hormone mimetic agents, for example 14. pyriproxifen d) molting hormone stimulants, such as 15·fenfeno (tebufenozide) 15 16·Mentfenozide e) Another 17·Chromfenozide -56- 200812490 18·Corne bugs (halofenozide) 20 fenoxycarb 2. Use of the active compound group as defined in the scope of claim 1 -57-20 200812490 5 for use in the control of animal pests An active compound of the formula and one for prevention, : 4^^, . The method is characterized in that a species of 1 to 20 insect growth regulators are used to act on the seeds at different time points. A method of preparing an insecticidal and acaricidal composition, characterized in that the active compound combination 7 is mixed with a stretching agent and/or a surfactant according to the application. • Use of an active compound composition according to claim 1 of the patent application for the treatment of seeds. • Use of an active compound composition according to claim 1 of the patent application for the treatment of a transgenic plant. Use of an active compound composition according to the scope of the patent application for the treatment of seeds of a transgenic plant. 10 • A seed treated with the active compound composition according to claim 1 of the scope of the patent application. lL According to the seed of the patent application, item 10, which is treated with an active compound of formula J and one to 20 insect growth regulators. 12. A seed according to claim 10, which is treated at a different time point by an active compound of formula I and from 1 to 20 insect growth regulators. 200812490 VII. Designation of representative representatives: (1) The representative representative of the case is: (No). (2) A brief description of the symbol of the representative figure: None 8. If there is a chemical formula in this case, please disclose the chemical formula that best shows the characteristics of the invention: