TW200800919A - Substituted pyrimidinyl oxime kinase inhibitors - Google Patents
Substituted pyrimidinyl oxime kinase inhibitors Download PDFInfo
- Publication number
- TW200800919A TW200800919A TW095147765A TW95147765A TW200800919A TW 200800919 A TW200800919 A TW 200800919A TW 095147765 A TW095147765 A TW 095147765A TW 95147765 A TW95147765 A TW 95147765A TW 200800919 A TW200800919 A TW 200800919A
- Authority
- TW
- Taiwan
- Prior art keywords
- alkyl
- group
- alkoxy
- amino
- aryl
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
- C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
- C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
- C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
- C07D239/46—Two or more oxygen, sulphur or nitrogen atoms
- C07D239/48—Two nitrogen atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US75263305P | 2005-12-21 | 2005-12-21 |
Publications (1)
Publication Number | Publication Date |
---|---|
TW200800919A true TW200800919A (en) | 2008-01-01 |
Family
ID=38256842
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
TW095147765A TW200800919A (en) | 2005-12-21 | 2006-12-20 | Substituted pyrimidinyl oxime kinase inhibitors |
Country Status (3)
Country | Link |
---|---|
AR (1) | AR058624A1 (es) |
TW (1) | TW200800919A (es) |
WO (1) | WO2007081630A2 (es) |
Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2015161479A1 (zh) * | 2014-04-24 | 2015-10-29 | 四川大学 | 一种嘧啶类化合物的抗宫颈癌用途 |
TWI750905B (zh) * | 2020-11-19 | 2021-12-21 | 財團法人國家衛生研究院 | 噻唑化合物作為蛋白質激酶抑制劑 |
Families Citing this family (14)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US7989465B2 (en) | 2007-10-19 | 2011-08-02 | Avila Therapeutics, Inc. | 4,6-disubstituted pyrimidines useful as kinase inhibitors |
US7982036B2 (en) | 2007-10-19 | 2011-07-19 | Avila Therapeutics, Inc. | 4,6-disubstitued pyrimidines useful as kinase inhibitors |
US20090111810A1 (en) * | 2007-10-23 | 2009-04-30 | Connolly Peter J | Substituted pyrimidine-5-carboxamide and 5-carboxylic ester kinase inhibitors |
EP2655362A1 (en) | 2010-12-22 | 2013-10-30 | Abbvie Inc. | Hepatitis c inhibitors and uses thereof |
RU2598849C2 (ru) * | 2011-02-24 | 2016-09-27 | Цзянсу Хэнсох Фармасьютикал Ко., Лтд. | Содержащие фосфор соединения в качестве ингибиторов протеинкина3 |
US9464079B2 (en) | 2011-03-23 | 2016-10-11 | Semorex Technologies Ltd. | Treatment of proliferative disorders with a chemiluminescent agent |
CN103058935B (zh) * | 2013-01-15 | 2015-05-06 | 四川大学 | 一种嘧啶类化合物及其制备方法和用途 |
US20160083343A1 (en) | 2013-03-15 | 2016-03-24 | Global Blood Therapeutics, Inc | Compounds and uses thereof for the modulation of hemoglobin |
AR096654A1 (es) * | 2013-06-20 | 2016-01-27 | Ab Science | Derivados de benzimidazol como inhibidores selectivos de proteína quinasa |
EA202092627A1 (ru) | 2013-11-18 | 2021-09-30 | Глобал Блад Терапьютикс, Инк. | Соединения и их применения для модуляции гемоглобина |
CN104744446B (zh) * | 2013-12-30 | 2019-06-25 | 广东东阳光药业有限公司 | 杂芳化合物及其在药物中的应用 |
FI3781561T3 (fi) | 2018-04-18 | 2024-06-13 | Constellation Pharmaceuticals Inc | Metyyliä muuntavien entsyymien modulaattoreita, niiden koostumuksia ja käyttöjä |
EP3797108B1 (en) | 2018-05-21 | 2022-07-20 | Constellation Pharmaceuticals, Inc. | Modulators of methyl modifying enzymes, compositions and uses thereof |
WO2021038419A1 (en) * | 2019-08-23 | 2021-03-04 | Insilico Medicine Ip Limited | Kinase inhibitors and methods of synthesis and treatment |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6878714B2 (en) * | 2001-01-12 | 2005-04-12 | Amgen Inc. | Substituted alkylamine derivatives and methods of use |
DE60234338D1 (de) * | 2001-06-01 | 2009-12-24 | Hoffmann La Roche | Pyrimidin, triazin und pyrazinderivate als glutamatrezeptoren |
HUP0401711A3 (en) * | 2001-06-26 | 2009-07-28 | Bristol Myers Squibb Co | N-heterocyclic inhibitors of tnf-alpha and pharmaceutical compositions containing them |
-
2006
- 2006-12-12 WO PCT/US2006/061890 patent/WO2007081630A2/en active Application Filing
- 2006-12-20 TW TW095147765A patent/TW200800919A/zh unknown
- 2006-12-21 AR ARP060105731A patent/AR058624A1/es not_active Application Discontinuation
Cited By (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2015161479A1 (zh) * | 2014-04-24 | 2015-10-29 | 四川大学 | 一种嘧啶类化合物的抗宫颈癌用途 |
US9840474B2 (en) | 2014-04-24 | 2017-12-12 | Sichuan University | Pyrimidine compounds and use as anti-cervical cancer thereof |
TWI750905B (zh) * | 2020-11-19 | 2021-12-21 | 財團法人國家衛生研究院 | 噻唑化合物作為蛋白質激酶抑制劑 |
Also Published As
Publication number | Publication date |
---|---|
WO2007081630A3 (en) | 2007-12-21 |
AR058624A1 (es) | 2008-02-13 |
WO2007081630A2 (en) | 2007-07-19 |
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