TW200730623A - Reprogramming and genetic modification of cells - Google Patents
Reprogramming and genetic modification of cellsInfo
- Publication number
- TW200730623A TW200730623A TW095141980A TW95141980A TW200730623A TW 200730623 A TW200730623 A TW 200730623A TW 095141980 A TW095141980 A TW 095141980A TW 95141980 A TW95141980 A TW 95141980A TW 200730623 A TW200730623 A TW 200730623A
- Authority
- TW
- Taiwan
- Prior art keywords
- cell
- cells
- reprogramming
- genetic modification
- fusing
- Prior art date
Links
- 238000012239 gene modification Methods 0.000 title abstract 2
- 230000005017 genetic modification Effects 0.000 title abstract 2
- 235000013617 genetically modified food Nutrition 0.000 title abstract 2
- 230000008672 reprogramming Effects 0.000 title abstract 2
- 210000004027 cell Anatomy 0.000 abstract 13
- 210000000349 chromosome Anatomy 0.000 abstract 3
- 229940124647 MEK inhibitor Drugs 0.000 abstract 2
- 238000000034 method Methods 0.000 abstract 2
- 239000002829 mitogen activated protein kinase inhibitor Substances 0.000 abstract 2
- 230000007910 cell fusion Effects 0.000 abstract 1
- 238000012258 culturing Methods 0.000 abstract 1
- 210000001840 diploid cell Anatomy 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/10—Cells modified by introduction of foreign genetic material
- C12N5/12—Fused cells, e.g. hybridomas
- C12N5/16—Animal cells
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/02—Preparation of hybrid cells by fusion of two or more cells, e.g. protoplast fusion
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/0696—Artificially induced pluripotent stem cells, e.g. iPS
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
- C12N2501/60—Transcription factors
- C12N2501/605—Nanog
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
- C12N2501/70—Enzymes
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
- C12N2501/999—Small molecules not provided for elsewhere
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2506/00—Differentiation of animal cells from one lineage to another; Differentiation of pluripotent cells
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2506/00—Differentiation of animal cells from one lineage to another; Differentiation of pluripotent cells
- C12N2506/02—Differentiation of animal cells from one lineage to another; Differentiation of pluripotent cells from embryonic cells
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Genetics & Genomics (AREA)
- Organic Chemistry (AREA)
- Biomedical Technology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical & Material Sciences (AREA)
- Zoology (AREA)
- Biotechnology (AREA)
- Wood Science & Technology (AREA)
- General Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Cell Biology (AREA)
- Microbiology (AREA)
- Physics & Mathematics (AREA)
- Plant Pathology (AREA)
- Molecular Biology (AREA)
- Biophysics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Developmental Biology & Embryology (AREA)
- Transplantation (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Materials For Medical Uses (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB0523039A GB0523039D0 (en) | 2005-11-11 | 2005-11-11 | Reprogramming and genetic modification of cells |
| GB0605998A GB0605998D0 (en) | 2006-03-24 | 2006-03-24 | Reprogramming And Genetic Modification Of Cells |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| TW200730623A true TW200730623A (en) | 2007-08-16 |
Family
ID=37763882
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| TW095141980A TW200730623A (en) | 2005-11-11 | 2006-11-13 | Reprogramming and genetic modification of cells |
Country Status (6)
| Country | Link |
|---|---|
| EP (1) | EP1957643A2 (enExample) |
| JP (1) | JP2009515515A (enExample) |
| AU (1) | AU2006313518A1 (enExample) |
| GB (2) | GB2445706A (enExample) |
| TW (1) | TW200730623A (enExample) |
| WO (1) | WO2007054720A1 (enExample) |
Families Citing this family (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US8129187B2 (en) | 2005-12-13 | 2012-03-06 | Kyoto University | Somatic cell reprogramming by retroviral vectors encoding Oct3/4. Klf4, c-Myc and Sox2 |
| US20090227032A1 (en) | 2005-12-13 | 2009-09-10 | Kyoto University | Nuclear reprogramming factor and induced pluripotent stem cells |
| EP2206724A1 (en) | 2005-12-13 | 2010-07-14 | Kyoto University | Nuclear reprogramming factor |
| US8278104B2 (en) | 2005-12-13 | 2012-10-02 | Kyoto University | Induced pluripotent stem cells produced with Oct3/4, Klf4 and Sox2 |
| GB0701062D0 (en) * | 2007-01-19 | 2007-02-28 | Evocell Ltd | Biological materials and uses thereof |
| JP2010528622A (ja) * | 2007-05-30 | 2010-08-26 | ザ ジェネラル ホスピタル コーポレイション | 体細胞から多能性細胞を生成する方法 |
| JP2008307007A (ja) | 2007-06-15 | 2008-12-25 | Bayer Schering Pharma Ag | 出生後のヒト組織由来未分化幹細胞から誘導したヒト多能性幹細胞 |
| US9213999B2 (en) | 2007-06-15 | 2015-12-15 | Kyoto University | Providing iPSCs to a customer |
| EP2090649A1 (en) | 2008-02-13 | 2009-08-19 | Fondazione Telethon | Method for reprogramming differentiated cells |
| AU2015201026B2 (en) * | 2008-03-17 | 2017-03-16 | The Scripps Research Institute | Combined chemical and genetic approaches for generation of induced pluripotent stem cells |
| JP5951254B2 (ja) * | 2008-03-17 | 2016-07-13 | ザ スクリプス リサーチ インスティテュート | 人工多能性幹細胞を作製するための化学的手法と遺伝的手法の組み合わせ法 |
| JP5346925B2 (ja) | 2008-05-02 | 2013-11-20 | 国立大学法人京都大学 | 核初期化方法 |
| EP2315829B1 (en) | 2008-08-08 | 2015-02-11 | Mayo Foundation For Medical Education And Research | Induced pluripotent stem cells |
| JP5645197B2 (ja) * | 2009-06-23 | 2014-12-24 | 学校法人日本大学 | 幹細胞の未分化状態を維持する新規方法 |
| US20130029416A1 (en) | 2011-07-22 | 2013-01-31 | Tayaramma Thatava | Differentiating induced pluripotent stem cells into glucose-responsive, insulin-secreting progeny |
| EP3283127B1 (en) * | 2015-04-15 | 2020-02-26 | University of Massachusetts | Compositions and methods for xi chromosome reactivation |
| CA3038721A1 (en) | 2016-09-30 | 2018-04-05 | Mayo Foundation For Medical Education And Research | Viral vectors for nuclear reprogramming |
-
2006
- 2006-11-13 TW TW095141980A patent/TW200730623A/zh unknown
- 2006-11-13 WO PCT/GB2006/004218 patent/WO2007054720A1/en not_active Ceased
- 2006-11-13 EP EP06808510A patent/EP1957643A2/en not_active Withdrawn
- 2006-11-13 GB GB0808244A patent/GB2445706A/en not_active Withdrawn
- 2006-11-13 AU AU2006313518A patent/AU2006313518A1/en not_active Abandoned
- 2006-11-13 JP JP2008539502A patent/JP2009515515A/ja active Pending
-
2007
- 2007-02-06 GB GB0702261A patent/GB2434155A/en not_active Withdrawn
Also Published As
| Publication number | Publication date |
|---|---|
| EP1957643A2 (en) | 2008-08-20 |
| WO2007054720A8 (en) | 2008-11-13 |
| GB0808244D0 (en) | 2008-06-11 |
| GB2445706A (en) | 2008-07-16 |
| WO2007054720A1 (en) | 2007-05-18 |
| GB0702261D0 (en) | 2007-03-14 |
| AU2006313518A2 (en) | 2008-06-26 |
| GB2434155A (en) | 2007-07-18 |
| JP2009515515A (ja) | 2009-04-16 |
| AU2006313518A1 (en) | 2007-05-18 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| GB0702261D0 (en) | No title | |
| Ivanov et al. | In vitro models of medulloblastoma: Choosing the right tool for the job | |
| NO20072719L (no) | Serumfritt cellekulturmedium for pattedyrceller | |
| PH12014502574B1 (en) | Methods and compositions for rna-directed target dna modification and for rna-directed modulation of transcription | |
| MX343271B (es) | Procesos de cultivo celular. | |
| NO20064379L (no) | Anvendelse av et serumfritt cellekulturmedium for produsjonen av IL-18BP i pattedyrceller | |
| WO2008154014A3 (en) | A method for culturing mammalian cells to improve recombinant protein production | |
| GB0706626D0 (en) | Medium and culture of embryonic stem cells | |
| ZA200703124B (en) | System and method for production of antibodies in plant cell culture | |
| EP2275531A4 (en) | METHOD FOR IMPROVING A PLURIPOTENTIAL STEM CELL | |
| MX338534B (es) | Poblaciones de celula madre de la placenta. | |
| ATE336567T1 (de) | Zellkulturmedium | |
| WO2010020876A3 (en) | Cell culture method to form aggregates | |
| EA201170025A1 (ru) | Способы повышения жизнеспособности и продукции культуры клеток | |
| NZ599479A (en) | Improved reverse genetics methods for virus rescue | |
| WO2009080299A8 (en) | Sm-protein based secretion engineering | |
| AU2008232699A8 (en) | High expression clones of mammalian cells with fluorescent protein A or G | |
| MY198223A (en) | Cell Culture Medium For Eukaryotic Cells | |
| WO2010115634A8 (en) | Method for improved single cell cloning | |
| WO2007056062A3 (en) | Methods for adapting mammalian cells | |
| AU2003242533A1 (en) | Glutamine-free medium | |
| MX2022008339A (es) | Metodo para producir una composicion que contiene un polipeptido con coloracion suprimida. | |
| MX2007005210A (es) | Medio de cultivo de celula libre de suero para las celulas de los mamiferos. | |
| GB2460977A (en) | Recombinant mammalian cell for screening a substance preventing and treating aids and screening method using the same | |
| WO2004053080A3 (en) | Clonal myeloma cell lines useful for manufacturing proteins in chemically defined media |