TW200637858A - Pharmaceutical compounds - Google Patents

Pharmaceutical compounds

Info

Publication number
TW200637858A
TW200637858A TW095101695A TW95101695A TW200637858A TW 200637858 A TW200637858 A TW 200637858A TW 095101695 A TW095101695 A TW 095101695A TW 95101695 A TW95101695 A TW 95101695A TW 200637858 A TW200637858 A TW 200637858A
Authority
TW
Taiwan
Prior art keywords
pharmaceutical compounds
compounds
tautomers
dichlorophenyl
solvates
Prior art date
Application number
TW095101695A
Other languages
Chinese (zh)
Inventor
Valerio Berdini
Adrian Liam Gill
Gary Trewartha
Andrew James Woodhead
Paul Graham Wyatt
Original Assignee
Astex Therapeutics Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB0501480A external-priority patent/GB0501480D0/en
Priority claimed from GB0501748A external-priority patent/GB0501748D0/en
Application filed by Astex Therapeutics Ltd filed Critical Astex Therapeutics Ltd
Publication of TW200637858A publication Critical patent/TW200637858A/en

Links

Abstract

The invention provides a compound of the formula (I): or salts, tautomers, solvates and N-oxides thereof; wherein: R1 is 2, 6-dichlorophenyl; R2a and R2b are both hydrogen; and R3 is a group: where R4 is C1-4 alkyl. The compounds have activity as inhibitors of CDK kinases and inhibit the proliferation of cancer cells.
TW095101695A 2005-01-21 2006-01-17 Pharmaceutical compounds TW200637858A (en)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US64621705P 2005-01-21 2005-01-21
GB0501480A GB0501480D0 (en) 2005-01-22 2005-01-22 Pharmaceutical compounds
GB0501748A GB0501748D0 (en) 2005-01-27 2005-01-27 Pharmaceutical compounds
US65133905P 2005-02-09 2005-02-09

Publications (1)

Publication Number Publication Date
TW200637858A true TW200637858A (en) 2006-11-01

Family

ID=45699652

Family Applications (3)

Application Number Title Priority Date Filing Date
TW095101695A TW200637858A (en) 2005-01-21 2006-01-17 Pharmaceutical compounds
TW095101704A TW200639170A (en) 2005-01-21 2006-01-17 Pharmaceutical compounds
TW095101705A TW200640922A (en) 2005-01-21 2006-01-17 Pharmaceutical compounds

Family Applications After (2)

Application Number Title Priority Date Filing Date
TW095101704A TW200639170A (en) 2005-01-21 2006-01-17 Pharmaceutical compounds
TW095101705A TW200640922A (en) 2005-01-21 2006-01-17 Pharmaceutical compounds

Country Status (3)

Country Link
GT (3) GT200600015A (en)
MY (1) MY139848A (en)
TW (3) TW200637858A (en)

Also Published As

Publication number Publication date
TW200640922A (en) 2006-12-01
GT200600014A (en) 2006-08-09
GT200600016A (en) 2006-08-09
GT200600015A (en) 2006-08-09
TW200639170A (en) 2006-11-16
MY139848A (en) 2009-11-30

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