TW200635941A - Chemical compounds - Google Patents

Chemical compounds

Info

Publication number
TW200635941A
TW200635941A TW094138749A TW94138749A TW200635941A TW 200635941 A TW200635941 A TW 200635941A TW 094138749 A TW094138749 A TW 094138749A TW 94138749 A TW94138749 A TW 94138749A TW 200635941 A TW200635941 A TW 200635941A
Authority
TW
Taiwan
Prior art keywords
chemical compounds
sarsasapogenin
solvated
crystalline
derivatives
Prior art date
Application number
TW094138749A
Other languages
English (en)
Inventor
Peter David Tiffin
Original Assignee
Phytopharm Plc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Phytopharm Plc filed Critical Phytopharm Plc
Publication of TW200635941A publication Critical patent/TW200635941A/zh

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J71/00—Steroids in which the cyclopenta(a)hydrophenanthrene skeleton is condensed with a heterocyclic ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J71/00—Steroids in which the cyclopenta(a)hydrophenanthrene skeleton is condensed with a heterocyclic ring
    • C07J71/0005—Oxygen-containing hetero ring
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/58—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids containing heterocyclic rings, e.g. danazol, stanozolol, pancuronium or digitogenin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/06—Antiasthmatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00—Drugs for disorders of the muscular or neuromuscular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00—Drugs for disorders of the muscular or neuromuscular system
    • A61P21/04—Drugs for disorders of the muscular or neuromuscular system for myasthenia gravis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A61P25/16—Anti-Parkinson drugs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/20—Hypnotics; Sedatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/04—Anorexiants; Antiobesity agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/02—Non-specific cardiovascular stimulants, e.g. drugs for syncope, antihypotensives

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Diabetes (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Psychiatry (AREA)
  • Hematology (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Pulmonology (AREA)
  • Obesity (AREA)
  • Psychology (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Anesthesiology (AREA)
  • Hospice & Palliative Care (AREA)
  • Virology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Endocrinology (AREA)
  • Child & Adolescent Psychology (AREA)
  • Dermatology (AREA)
  • Emergency Medicine (AREA)
TW094138749A 2004-11-05 2005-11-04 Chemical compounds TW200635941A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB0424528A GB0424528D0 (en) 2004-11-05 2004-11-05 Chemical compounds

Publications (1)

Publication Number Publication Date
TW200635941A true TW200635941A (en) 2006-10-16

Family

ID=33523268

Family Applications (1)

Application Number Title Priority Date Filing Date
TW094138749A TW200635941A (en) 2004-11-05 2005-11-04 Chemical compounds

Country Status (17)

Country Link
US (1) US20080194530A1 (zh)
EP (2) EP2479183A3 (zh)
JP (1) JP2008519020A (zh)
KR (1) KR20070089798A (zh)
CN (2) CN102219826A (zh)
AU (1) AU2005300348A1 (zh)
BR (1) BRPI0517648A (zh)
CA (1) CA2584676A1 (zh)
GB (1) GB0424528D0 (zh)
IL (1) IL182879A0 (zh)
MX (1) MX2007005473A (zh)
NO (1) NO20072794L (zh)
RU (1) RU2007119611A (zh)
SG (1) SG158068A1 (zh)
TW (1) TW200635941A (zh)
WO (1) WO2006048665A2 (zh)
ZA (1) ZA200703630B (zh)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2010084356A1 (en) 2009-01-24 2010-07-29 Phytopharm Plc Treatment of neurotrophic factor mediated disorders
BR112013001422A2 (pt) 2010-07-20 2019-09-24 Phytopharm Plc metodo para tratar ou previnir disturbios induzidos por l-dopa, agonista dopamina e/ou acentuador de dopamina em um individuo que necessita dos mesmos, agente, composição, uso de ou mais agentes e metodo para tratar a doença de parkinson
JP5881525B2 (ja) * 2011-05-16 2016-03-09 ライオン株式会社 サポゲニン安定化組成物の製造方法

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2306635A (en) * 1940-08-03 1942-12-29 Parke Davis & Co Method for the preparation of steroidal carbinols
US2408827A (en) * 1944-05-15 1946-10-08 Parke Davis & Co Steroidal compounds and methods for obtaining the same
US2774714A (en) * 1952-10-10 1956-12-18 Emanuel B Hershberg Process for the extraction of sapogenins from plant materials
US3019220A (en) * 1958-07-17 1962-01-30 Julian Lab Inc Isolation of sapogenins
US4057543A (en) * 1976-07-01 1977-11-08 G. D. Searle & Co. Process for the preparation of 17β-hydroxy-3-oxo-17α-pregn-4-ene-21-carboxylic acid γ-lactone
US4680289A (en) 1985-06-05 1987-07-14 Progenics, Inc. Treatment of obesity and diabetes using sapogenins
JPH04230696A (ja) * 1990-12-28 1992-08-19 Sanwa Shiyouyaku Kk 新規なステロイド系化合物および制癌剤
CN1033754C (zh) * 1993-05-31 1997-01-08 上海第二医科大学 知母皂甙元作为制备β肾上腺素和M胆碱受体双向调节药的用途及其制法
KR100217996B1 (ko) * 1996-12-23 1999-09-01 윤종용 프린트 헤드의 노즐 간격 보상 장치 및 방법
GB9923076D0 (en) 1999-09-29 1999-12-01 Phytopharm Plc Sapogenin derivatives and their use
TR200002774T2 (tr) 1998-03-26 2001-06-21 Phytopharm Plc Alzheimer hastalığının tedavisi için steroit sapogenler ve bunların türevleri
GB0000228D0 (en) 2000-01-06 2000-03-01 Phytopharm Plc Fluoro substituted sapogenins and their use
AT409100B (de) 2000-07-24 2002-05-27 Evg Entwicklung Verwert Ges Vorrichtung zum schweissen einer drahtgittermatte
GB0107822D0 (en) 2001-03-28 2001-05-23 Phytopharm Plc Sapogenin derivatives their synthesis and use methods based upon their use
RU2332999C2 (ru) 2002-03-27 2008-09-10 ФИТОФАРМ ПиЭлСи Терапевтические способы и применения сапогенинов и их производных

Also Published As

Publication number Publication date
JP2008519020A (ja) 2008-06-05
CN102219826A (zh) 2011-10-19
RU2007119611A (ru) 2008-12-10
CN101068827B (zh) 2011-06-08
GB0424528D0 (en) 2004-12-08
KR20070089798A (ko) 2007-09-03
WO2006048665A2 (en) 2006-05-11
EP1809650A2 (en) 2007-07-25
US20080194530A1 (en) 2008-08-14
NO20072794L (no) 2007-07-31
ZA200703630B (en) 2009-10-28
IL182879A0 (en) 2007-08-19
SG158068A1 (en) 2010-01-29
EP2479183A2 (en) 2012-07-25
MX2007005473A (es) 2007-05-24
CN101068827A (zh) 2007-11-07
WO2006048665A3 (en) 2006-09-08
CA2584676A1 (en) 2006-05-11
EP2479183A3 (en) 2013-08-28
AU2005300348A1 (en) 2006-05-11
BRPI0517648A (pt) 2008-10-14

Similar Documents

Publication Publication Date Title
ZA200709856B (en) Fluorene derivatives,compositions containing said derivatives and the use thereof
HK1094433A1 (en) Flocculating agent, method for the production and use thereof
HK1093731A1 (en) Sulfoximine-substituted pyrimidines for use as cdk and/or vegf inhibitors, the production thereof and their use as drugs
WO2007078838A3 (en) Solid biocide composition and sealed biocide article
IL179919A0 (en) Neural stem cells, compositions containing the same and methods for promoting the division thereof
EP1492160A4 (en) EVAPORATOR, MISCELLANEOUS, THESE USES AND EVAPORATING METHOD
AU2006321904A8 (en) 1, 1, 3-trioxo-1 , 2 , 5-thiadiazolidines and their use as PTP-ases inhibitors
IL169318A0 (en) Pyrimidines, methods for the production thereof, and use thereof
WO2006133055A3 (en) Method and composition for increasing the alkalinity of the body
TW200635941A (en) Chemical compounds
MX263097B (es) Inhibidores de entrada a moleculas pequenas.
GB0417803D0 (en) Algorithmic trading
SG155165A1 (en) Crystalline and amorphous forms of smilagenin
WO2008021518A3 (en) Crystalline forms of tiagabine hydrochloride and processes for the preparation of amorphous tiagabine hydrochloride
IL181313A0 (en) 6-phenyl-7-amino-triazolopyrimidines, methods for the production thereof, the use thereof for controlling pathogenic fungi, and agents containing the same
WO2003099783A3 (en) Tropane compounds
AU2003258616A1 (en) Device for turning flat mailing items through 900
AP2244A (en) Topical methadone compositions and methods for using the same.
GB0514628D0 (en) 2,6,8-trisubstituted purines and their different uses
CA118270S (en) Wrench set case
AU2005904583A0 (en) Reminder Device
ZA200404236B (en) Shears or the like.
AU2005904753A0 (en) Male contraceptive device
GB0413845D0 (en) The treatment of emesis
GB0317135D0 (en) The treatment of emesis