TW200606174A - Processes for preparation of 9,11-epoxy steroids and intermediates useful therein - Google Patents
Processes for preparation of 9,11-epoxy steroids and intermediates useful thereinInfo
- Publication number
- TW200606174A TW200606174A TW094131840A TW94131840A TW200606174A TW 200606174 A TW200606174 A TW 200606174A TW 094131840 A TW094131840 A TW 094131840A TW 94131840 A TW94131840 A TW 94131840A TW 200606174 A TW200606174 A TW 200606174A
- Authority
- TW
- Taiwan
- Prior art keywords
- group
- hydroxyalkyl
- hydroxycarbonyl
- alkoxyalkyl
- aryloxy
- Prior art date
Links
Landscapes
- Steroid Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
Multiple novel reaction schemes, novel process steps and novel intermediates are provided for the synthesis of epoxymexrenone and other compounds of Formula I, wherein: -A-A- represents the group -CHR4-CHR5- or -CR4=CR5-R3, R4 and R5 are independently selected from the group consisting of hydrogen, halo, hydroxy, lower alkyl, lower alkoxy, hydroxyalkyl, alkoxyalkyl, hydroxycarbonyl, cyano, aryloxy; R1 represents an alpha-oriented lower alkoxycarbonyl or hydroxyalkyl radical; -B-B- represents the group -CHR6-CHR7- or an alpha- or beta-oriented group: where R6 and R7 are independently selected from the group consisting of hydrogen, halo, lower alkoxy, acyl, hydroxyalkyl, alkoxyalkyl, hydroxycarbonyl, alkyl, alkoxycarbonyl, acyloxyalkyl, cyano and aryloxy; and R8 and R9 are independently selected from the group consisting of hydrogen, hydroxy, halo, lower alkoxy, acyl, hydroxyalkyl, alkoxyalkyl, hydroxycarbonyl, alkyl, alkoxycarbonyl, acyloxyalkyl, cyano and aryloxy, or R8 and R9 together comprise a carbocyclic or heterocyclic ring structure, or R8 or R9 together with R6 or R7 comprise a carbocyclic or heterocyclic ring structure fused to the pentacyclic D ring.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US4938897P | 1997-06-11 | 1997-06-11 |
Publications (2)
Publication Number | Publication Date |
---|---|
TW200606174A true TW200606174A (en) | 2006-02-16 |
TWI277620B TWI277620B (en) | 2007-04-01 |
Family
ID=21959557
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
TW87109305A TWI248443B (en) | 1997-06-11 | 1998-09-03 | Processes for preparation of 9,11-epoxy steroids and intermediates useful therein |
TW94131840A TWI277620B (en) | 1997-06-11 | 1998-09-03 | Processes for preparation of 9,11-epoxy steroids and intermediates useful therein |
Family Applications Before (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
TW87109305A TWI248443B (en) | 1997-06-11 | 1998-09-03 | Processes for preparation of 9,11-epoxy steroids and intermediates useful therein |
Country Status (4)
Country | Link |
---|---|
AR (2) | AR043268A1 (en) |
PL (1) | PL189757B1 (en) |
TW (2) | TWI248443B (en) |
ZA (1) | ZA985088B (en) |
Families Citing this family (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN112723321A (en) * | 2021-01-26 | 2021-04-30 | 呼伦贝尔驰宏矿业有限公司 | Acid cross-linking system and acid cross-linking process for industrial sulfuric acid preparation purification section |
CN114456952B (en) * | 2022-02-22 | 2023-04-14 | 昆明理工大学 | Chrysosporium and application thereof |
-
1997
- 1997-12-11 PL PL97368692A patent/PL189757B1/en not_active IP Right Cessation
-
1998
- 1998-06-11 ZA ZA985088A patent/ZA985088B/en unknown
- 1998-06-11 AR ARP980102772 patent/AR043268A1/en unknown
- 1998-09-03 TW TW87109305A patent/TWI248443B/en not_active IP Right Cessation
- 1998-09-03 TW TW94131840A patent/TWI277620B/en not_active IP Right Cessation
-
2007
- 2007-04-23 AR ARP070101746A patent/AR060624A2/en unknown
Also Published As
Publication number | Publication date |
---|---|
PL189757B1 (en) | 2005-09-30 |
TWI248443B (en) | 2006-02-01 |
ZA985088B (en) | 1999-06-11 |
TWI277620B (en) | 2007-04-01 |
AR060624A2 (en) | 2008-07-02 |
AR043268A1 (en) | 2005-07-27 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
MM4A | Annulment or lapse of patent due to non-payment of fees |